| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stuart J McDougall, Zhi Yi Ong, Rosa Heller, Anna Horton, Kimberly K Thek, Eun A Choi, Gavan P McNally, Andrew J Lawrenc. Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus. Journal of neurochemistry. 2024-07-20. PMID:39032068. |
a subpopulation of nts neurons project to the nucleus accumbens (nac); however, the function of this nts-nac pathway remains unknown. |
2024-07-20 |
2024-07-24 |
mouse |
| Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Ágota Ádám, András Csilla. Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice. Frontiers in neuroanatomy. vol 18. 2024-07-19. PMID:39026519. |
previous quantitative morphometric studies from our laboratory showed a marked reduction and defasciculation of the mesotelencephalic dopaminergic pathway of vpa treated mice, along with a decrease in tissue dopamine in the nucleus accumbens (nac), but not in the caudatoputamen (cpu). |
2024-07-19 |
2024-07-21 |
mouse |
| Freddyson J Martínez-Rivera, Yun Young Yim, Arthur Godino, Angélica Minier-Toribio, Solange Tofani, Leanne M Holt, Angélica Torres-Berrío, Rita Futamura, Caleb J Browne, Tamara Markovic, Peter J Hamilton, Rachael L Neve, Eric J Nestle. Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026727. |
these neurobiological processes in brain reward regions, such as the nucleus accumbens (nac), are orchestrated in large part by transcriptional regulation. |
2024-07-19 |
2024-07-21 |
mouse |
| Alejandro Dorado, Juan Lorenzo Terrasa, Marian van der Meulen, Pedro Montoya, Ana María González-Roldá. Altered endogenous pain inhibitory function in older adults with chronic pain is associated with disruptions in functional connectivity during resting state. The journal of pain. 2024-07-19. PMID:39029880. |
older adults with chronic pain displayed higher connectivity between primary somatosensory cortex and nucleus accumbens (nac) than pain-free older adults. |
2024-07-19 |
2024-07-22 |
human |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |
| Swarup Mitra, Craig T Werner, Treefa Shwani, Ana Garcia Lopez, Dale Federico, Kate Higdon, Xiaofang Li, Pedro H Gobira, Shruthi A Thomas, Jennifer A Martin, Chunna An, Ramesh Chandra, Ian Maze, Rachel Neve, Mary Kay Lobo, Amy M Gancarz, David M Diet. A Novel Role for the Histone Demethylase JMJD3 in Mediating Heroin-induced Relapse-Like Behaviors. Biological psychiatry. 2024-07-17. PMID:39019389. |
we examined how histone demethylase jmjd3 in the nucleus accumbens (nac) influences heroin seeking after abstinence from self-administration. |
2024-07-17 |
2024-07-20 |
Not clear |
| Sarah Warren Gooding, Elinor Lewis, Christine Chau, Suhail Sandhu, Julianna Glienke, Jennifer L Whistle. Nucleus accumbens sub-regions experience distinct dopamine release responses following acute and chronic morphine exposure. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005415. |
recent work suggests that distinct vta projections that target the medial and lateral shell of the nucleus accumbens (nac), may play opposing roles in modulating behavior. |
2024-07-15 |
2024-07-18 |
mouse |
| Elizabeth A Eckenwiler, Anna E Ingebretson, Jeffrey J Stolley, Maxine A Fusaro, Alyssa M Romportl, Jack M Ross, Christopher L Petersen, Eera M Kale, Michael S Clark, Selena S Schattauer, Larry S Zweifel, Julia C Lemo. CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005420. |
the nucleus accumbens (nac) mediates reward learning and motivation. |
2024-07-15 |
2024-07-18 |
Not clear |
| Spencer B Huggett, Sharmila Selveraj, John E McGeary, Ami Ikeda, Emerald Yuan, Lauren B Loeffel, Rohan H C Palme. Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005451. |
this study explores the neurobiological underpinnings of alcohol use disorder (aud) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (pfc), nucleus accumbens (nac), and central amygdala (cea)). |
2024-07-15 |
2024-07-18 |
mouse |
| Heather C Aziz, Regina A Mangier. Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice. Biology of sex differences. vol 15. issue 1. 2024-07-13. PMID:39003495. |
the nucleus accumbens (nac), a striatal brain region composed of the core (nacc) and shell (nacsh), has been linked to risk-taking behavior and implicated in reward seeking and evaluation. |
2024-07-13 |
2024-07-16 |
mouse |
| Alexandra Polyzou, Joachim Fuchs, Cristina Kroon, Androniki Kotoula, Foteini Delis, Paul Turko, Katerina Antoniou, Britta Eickholt, George Leondariti. Cell type-specific and subcellular expression of phospholipid phosphatase-related proteins to modulate lyso-phosphatidic acid synaptic signaling in the developing and adult CNS. Journal of neurochemistry. 2024-07-12. PMID:38994820. |
expression patterns of plppr2,4 and 5 were consistent with previous studies, whereas plppr3 and plppr1 exhibited a unique expression profile in nucleus accumbens (nac) and striatum in later developmental and adult stages, which we verified at the protein level for plppr3. |
2024-07-12 |
2024-07-14 |
mouse |
| Randal A Serafini, Zahra Farzinpour, Vishwendra Patel, Abigail M Kelley, Molly Estill, Kerri D Pryce, Farhana Sakloth, Collin D Teague, Angelica Torres-Berrio, Eric J Nestler, Li Shen, Schahram Akbarian, Anushree N Karkhanis, Robert D Blitzer, Venetia Zachario. Nucleus accumbens myocyte enhancer factor 2C mediates the maintenance of peripheral nerve injury-induced physiological and behavioral maladaptations. Pain. 2024-07-10. PMID:38985454. |
preclinical and clinical work has demonstrated altered plasticity and activity in the nucleus accumbens (nac) under chronic pain states, highlighting critical therapeutic avenues for the management of chronic pain conditions. |
2024-07-10 |
2024-07-12 |
mouse |
| Kimberly L P Long, Nerissa E G Hoglen, Alex J Keip, Robert M Klinkel, DéJenaé L See, Joseph Maa, Jenna C Wong, Michael Sherman, Devanand S Manol. Oxytocin receptor function regulates neural signatures of pair bonding and fidelity in the nucleus accumbens. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979148. |
signaling via the oxytocin receptor (oxtr) in the nucleus accumbens (nac) facilitates social reward as well as pair bond formation between mates in socially monogamous prairie voles |
2024-07-09 |
2024-07-12 |
Not clear |
| Gaojie Pan, Bing Zhao, Mutian Zhang, Yanan Guo, Yuhua Yan, Dan Dai, Xiaoxi Zhang, Hui Yang, Jinfei Ni, Zhili Huang, Xia Li, Shumin Dua. Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State. Neuroscience bulletin. 2024-07-09. PMID:38980648. |
the nucleus accumbens (nac) plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness. |
2024-07-09 |
2024-07-12 |
Not clear |
| Angélica Torres-Berrío, Molly Estill, Vishwendra Patel, Aarthi Ramakrishnan, Hope Kronman, Angélica Minier-Toribio, Orna Issler, Caleb J Browne, Eric M Parise, Yentl Y van der Zee, Deena M Walker, Freddyson J Martínez-Rivera, Casey K Lardner, Romain Durand-de Cuttoli, Scott J Russo, Li Shen, Simone Sidoli, Eric J Nestle. Mono-methylation of lysine 27 at histone 3 confers lifelong susceptibility to stress. Neuron. 2024-07-03. PMID:38959894. |
specifically, mice susceptible to early life stress (els) or chronic social defeat stress (csds) displayed increased h3k27me1 enrichment in the nucleus accumbens (nac), a key brain-reward region. |
2024-07-03 |
2024-07-10 |
mouse |
| Danial Farmani, Seyed Mohammadmisagh Moteshakereh, Mohammad Nikoohemmat, Reyhaneh Askari, Sakineh Salehi, Abbas Haghparas. Restraint stress-induced antinociceptive effects in acute pain: Involvement of orexinergic system in the nucleus accumbens. Behavioural brain research. 2024-07-03. PMID:38960330. |
the studies demonstrated that the nucleus accumbens (nac) is critical in modulating pain. |
2024-07-03 |
2024-07-10 |
rat |
| Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. |
the pfc interacts with the brain's reward system, including the ventral tegmental area (vta) and nucleus accumbens (nac). |
2024-07-02 |
2024-07-06 |
Not clear |
| Kasey L Brida, Emily T Jorgensen, Robert A Phillips, Catherine E Newman, Jennifer J Tuscher, Emily K Morring, Morgan E Zipperly, Lara Ianov, Kelsey D Montgomery, Madhavi Tippani, Thomas M Hyde, Kristen R Maynard, Keri Martinowich, Jeremy J Da. Reelin marks cocaine-activated striatal ensembles, promotes neuronal excitability, and regulates cocaine reward. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948801. |
drugs of abuse activate defined neuronal ensembles in brain reward structures such as the nucleus accumbens (nac), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. |
2024-07-01 |
2024-07-03 |
Not clear |
| Natalia F Sardi, Ana C Pescador, Karla E Torres-Chavez, Luana Fische. Revealing a role of brainstem monoaminergic nuclei on the pronociceptive effect of sleep restriction. Neuropharmacology. 2024-07-01. PMID:38950692. |
we have recently demonstrated the involvement of nucleus accumbens (nac) and anterior cingulate cortex (acc) in the pronociceptive effect of sleep restriction. |
2024-07-01 |
2024-07-04 |
rat |
| Liv Engel, Amy R Wolff, Madelyn Blake, Val L Collins, Sonal Sinha, Benjamin T Saunder. Dopamine neurons drive spatiotemporally heterogeneous striatal dopamine signals during learning. Current biology : CB. 2024-06-26. PMID:38925117. |
we used a fluorescent biosensor to monitor dopamine in the nucleus accumbens (nac) core and shell, dorsomedial striatum (dms), and dorsolateral striatum (dls). |
2024-06-26 |
2024-06-29 |
Not clear |