All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Kimberly C Thibeault, Michael Z Leonard, Veronika Kondev, Soren D Emerson, Rishik Bethi, Alberto J Lopez, Jonathon P Sens, Brett P Nabit, Hannah B Elam, Danny G Winder, Sachin Patel, Drew D Kiraly, Brad A Grueter, Erin S Calipar. A cocaine-activated ensemble exerts increased control over behavior while decreasing in size. Biological psychiatry. 2024-06-20. PMID:38901723. substance use disorder (sud) is characterized by long-lasting changes in reward-related brain regions, such as the nucleus accumbens (nac). 2024-06-20 2024-06-23 Not clear
Laszlo Peczely, Anthony A Grac. The dose-dependent effect of the D2R agonist quinpirole microinjected into the ventral pallidum on information flow in the limbic system. Progress in neuro-psychopharmacology & biological psychiatry. 2024-06-20. PMID:38901759. the ventral pallidum (vp) receives its primary inputs from the nucleus accumbens (nac) and the basolateral amygdala (bla). 2024-06-20 2024-06-23 Not clear
Sydney E Ashton, Paul Sharalla, Naru Kang, Adam T Brockett, Margaret M McCarthy, Matthew R Roesc. Distinct action signals by subregions in nucleus accumbens during STOP-change performance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897724. nucleus accumbens (nac) is thought to contribute to motivated behavior by signaling the value of reward-predicting cues and the delivery of anticipated reward. 2024-06-19 2024-06-22 rat
Dusti Shay, Rebecca Welly, Jiude Mao, Jessica Kinkade, Joshua K Brown, Cheryl S Rosenfeld, Victoria J Vieira-Potte. Knockdown of Esr1 from DRD1-Rich Brain Regions Affects Adipose Tissue Metabolism: Potential Crosstalk between Nucleus Accumbens and Adipose Tissue. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892320. mechanisms are not fully understood, but e2's effects on dopamine (da) activity in the nucleus accumbens (nac) brain region may mediate changes in mood and voluntary physical activity (pa). 2024-06-19 2024-06-21 mouse
Brandon Taraku, Joana R Loureiro, Ashish K Sahib, Artemis Zavaliangos-Petropulu, Noor Al-Sharif, Amber M Leaver, Benjamin Wade, Shantanu Joshi, Roger P Woods, Randall Espinoza, Katherine L Nar. Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression. Brain and behavior. vol 14. issue 6. 2024-06-19. PMID:38894648. major depressive disorder (mdd) is associated with dysfunctional reward processing, which involves functional circuitry of the habenula (hb) and nucleus accumbens (nac). 2024-06-19 2024-06-21 Not clear
Giuseppe Aceto, Luca Nardella, Simona Nanni, Valeria Pecci, Alessia Bertozzi, Sofia Nutarelli, Maria Teresa Viscomi, Claudia Colussi, Marcello D'Ascenzo, Claudio Grass. Glycine-induced activation of GPR158 increases the intrinsic excitability of medium spiny neurons in the nucleus accumbens. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-06-17. PMID:38884814. gpr158 is highly expressed in the nucleus accumbens (nac), a major input structure of the basal ganglia that integrates information from cortical and subcortical structures to mediate goal-directed behaviors. 2024-06-17 2024-06-19 Not clear
Zachary W Hoisington, Alexandra Salvi, Sophie Laguesse, Yann Ehinger, Chhavi Shukla, Khanhky Phamluong, Dorit Ro. The small G-protein Rac1 in the dorsomedial striatum promotes alcohol-dependent structural plasticity and goal-directed learning in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-17. PMID:38886056. actin is a major component of dendritic spines, and we previously found that alcohol alters actin composition and dendritic spine structure in the nucleus accumbens (nac) and the dorsomedial striatum (dms). 2024-06-17 2024-06-21 mouse
Jose A Pochapski, Alexander Gómez-A, Sierra J Stringfield, Hannah Jaggers, Charlotte A Boettiger, Claudio Da Cunha, Donita L Robinso. Adolescent alcohol exposure persistently alters orbitofrontal cortical encoding of Pavlovian conditional stimulus components in female rats. Scientific reports. vol 14. issue 1. 2024-06-14. PMID:38877100. we hypothesized that aie in female rats increases conditional approach to a reward-predictive cue and corresponding neuronal activity in the orbitofrontal cortex (ofc) and nucleus accumbens (nac). 2024-06-14 2024-06-17 rat
Simin Deng, Si Tan, Cuihua Guo, Yanxiong Liu, Xiuhong L. Impaired effective functional connectivity in the social preference of children with autism spectrum disorder. Frontiers in neuroscience. vol 18. 2024-06-14. PMID:38872942. the medial prefrontal cortex (mpfc), amygdala (amyg), and nucleus accumbens (nac) have been identified as critical players in the social preference of individuals with asd. 2024-06-14 2024-06-16 Not clear
Youssef Sari, Ghadeer M S Swiss, Fatin A Alrashedi, Kholoud A Baeshen, Sultan A Alshammari, Shakir D Alsharari, Nemat Ali, Abdullah F Alasmari, Ali Alhoshani, Alaa A Alameen, Wayne E Childers, Magid Abou-Gharbia, Fawaz Alasmar. Effects of novel beta-lactam, MC-100093, and ceftriaxone on astrocytic glutamate transporters and neuroinflammatory factors in nucleus accumbens of C57BL/6 mice exposed to escalated doses of morphine. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 32. issue 7. 2024-06-13. PMID:38868175. in this study, we investigated the effects of escalating doses of morphine and tested the efficacy of novel synthetic non-antibiotic drug, mc-100093, and ceftriaxone in attenuating the effects of morphine exposure in the expression of glt-1, xct, and neuroinflammatory factors (il-6 and tgf-β) in the nucleus accumbens (nac). 2024-06-13 2024-06-15 mouse
Ivette L Gonzalez, Christopher A Turner, Paras R Patel, Noah B Leonardo, Brandon D Luma, Julianna M Richie, Dawen Cai, Cynthia A Chestek, Jill B Becke. Sex Differences in Dopamine Release in Nucleus Accumbens and Dorsal Striatum Determined by Chronic Fast Scan Cyclic Voltammetry: Effects of social housing and repeated stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-12. PMID:38866486. we investigated sex differences in dopamine (da) release in the nucleus accumbens (nac) and dorsolateral striatum (dls) using a chronic 16-channel carbon fiber electrode and fast-scan cyclic voltammetry (fscv). 2024-06-12 2024-06-15 rat
Shinbe Choi, Michael R Noya, Eugene A Kiyatki. Oxygen fluctuations in the brain and periphery induced by intravenous fentanyl: effects of dose and drug experience. Journal of neurophysiology. 2024-06-12. PMID:38863429. to explore this discrepancy, we designed a study incorporating electrochemical assessment of oxygen in the brain (nucleus accumbens; nac) and subcutaneous (sc) space, multi-site thermorecording (brain, skin, muscle), and locomotor activity at varying doses of fentanyl (1.0, 3.0, 10, 30, 90 µg/kg) in rats. 2024-06-12 2024-06-14 rat
Santiago A Forero, Sydney Liu, Netra Shetty, Alexander G Ophi. Re-wiring of the bonded brain: Gene expression among pair bonded female prairie voles changes as they transition to motherhood. Genes, brain, and behavior. vol 23. issue 3. 2024-06-11. PMID:38861664. we measured mrna expression of genes encoding receptors for oxytocin (oxtr), dopamine (d1r and d2r), mu-opioids (oprm1a), and kappa-opioids (oprk1a) within three brain areas processing salience of sociosensory cues (anterior cingulate cortex; acc), pair bonding (nucleus accumbens; nac), and maternal care (medial preoptic area; mpoa). 2024-06-11 2024-06-14 Not clear
Melody C Iacino, Taylor A Stowe, Elizabeth G Pitts, Lacey L Sexton, Shannon L Macauley, Mark J Ferri. A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats. eLife. vol 13. 2024-06-11. PMID:38860652. here, we utilized fast scan cyclic voltammetry and microdialysis to examine differences in dopamine release as well as mechanisms that underlie differential dopamine signaling in the nucleus accumbens (nac) core of adolescent (p28-35) and adult (p70-90) male rats. 2024-06-11 2024-06-14 rat
Yan-Ping Lan, Chen-Zhe Ding, Jian-Xue Xia, Yun-Zhen Yang, Yan-Bin Zha. Analysis of the functional role and mRNA expression of GABABR in the nucleus accumbens of cocaine-addicted rats. Journal of the Chinese Medical Association : JCMA. 2024-06-11. PMID:38860774. the nucleus accumbens (nac) is closely related to addiction-related learning memory, and γ-aminobutyric acid type b receptor (gababr) is a potential target for the treatment of drug addiction. 2024-06-11 2024-06-14 rat
Pan Xu, Gyeongah Park, Xiaoqian Sun, Qian Ge, Zhen Jin, Chien-Hsien Lai, Xiaojie Liu, Qingsong Liu, Rahul Simha, Chen Zeng, Jianyang Du, Hui L. Different emotional states engage distinct descending pathways from the prefrontal cortex. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853906. using in vivo calcium imaging, electrophysiology, and optogenetics, we examined neural circuit dynamics in the medial prefrontal cortex (mpfc), targeting two key areas: the basal lateral amygdala (bla) and nucleus accumbens (nac). 2024-06-10 2024-06-14 Not clear
Richard Quansah Amissah, Hakan Kayir, Malik Asfandyaar Talhat, Ahmad Hassan, Yu Gu, Ron Johnson, Karolina Urban, Jibran Y Khokha. The Journal of pharmacology and experimental therapeutics. 2024-06-06. PMID:38844363. sprague-dawley rats (6 males, 7 females) were implanted with electrodes in the prefrontal cortex (pfc), dorsal hippocampus (dhipp), cingulate cortex (cg), and nucleus accumbens (nac). 2024-06-06 2024-06-10 rat
Roghayeh Mozafari, Fariba Khodagholi, Neda Kaveh, Mohammad Esmail Zibaii, Peter Kalivas, Abbas Haghparas. Blockade of mGluR5 in nucleus accumbens modulates calcium sensor proteins, facilitates extinction, and attenuates reinstated morphine place preference in rats. Journal of psychiatric research. vol 176. 2024-06-04. PMID:38833749. here we focused on the role of mglur5 in the nucleus accumbens (nac) as a main site of glutamate action on the rewarding effects of morphine. 2024-06-04 2024-06-07 rat
Yao Shen, Xinshuang Gong, Liyin Qian, Yuer Ruan, Shujun Lin, Zhaoying Yu, Zizhen Si, Wenting Wei, Yu Li. Inhibition of GSDMD-dependent pyroptosis decreased methamphetamine self-administration in rats. Brain, behavior, and immunity. 2024-06-04. PMID:38834156. the present study firstly investigated whether the membrane pore information induced by gsdmd-dependent pyroptosis was associated with the increased da levels in the ventral tegmental area (vat) and nucleus accumbens (nac) of rats self-administering meth and sy-sh5y cells treated by meth. 2024-06-04 2024-06-07 rat
Megan Ulmer Carnes, Bryan C Quach, Linran Zhou, Shizhong Han, Ran Tao, Meisha Mandal, Amy Deep-Soboslay, Jesse A Marks, Grier P Page, Brion S Maher, Andrew E Jaffe, Hyejung Won, Laura J Bierut, Thomas M Hyde, Joel E Kleinman, Eric O Johnson, Dana B Hancoc. Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-03. PMID:38830989. we used genome-wide genotype, dna methylation, and rna sequencing data in postmortem human nucleus accumbens (nac) to identify cis-methylation/expression quantitative trait loci (meqtls/eqtls), investigate variant-by-cigarette smoking interactions across the genome, and overlay qtl evidence at smoking gwas-identified loci to evaluate their regulatory potential. 2024-06-03 2024-06-06 human