| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sunila G Nair, Nicholas S Strand, John F Neumaie. DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function. Brain research. vol 1511. 2013-12-09. PMID:23085473. |
using a gi/o-coupled dreadd, we found that inhibition of the lhb reduces depression-like behavior in the forced swim test in a manner that suggests enhanced serotonergic activity. |
2013-12-09 |
2023-08-12 |
Not clear |
| Hidenori Aizawa, Shin Yanagihara, Megumi Kobayashi, Kazue Niisato, Takashi Takekawa, Rie Harukuni, Thomas J McHugh, Tomoki Fukai, Yoshikazu Isomura, Hitoshi Okamot. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678132. |
furthermore, this inhibitory effect of lhb lesion on theta maintenance depended upon an intact serotonergic median raphe, suggesting that lhb activity plays an essential role in maintaining hippocampal theta oscillation via the serotonergic raphe. |
2013-08-02 |
2023-08-12 |
rat |
| Hidenori Aizawa, Shin Yanagihara, Megumi Kobayashi, Kazue Niisato, Takashi Takekawa, Rie Harukuni, Thomas J McHugh, Tomoki Fukai, Yoshikazu Isomura, Hitoshi Okamot. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678132. |
since serotonin is known to negatively regulate theta oscillation in the hippocampus, phase-locking activity of the lhb neurons may act, under the influence of the dbb, to maintain the hippocampal theta oscillation by modulating the activity of serotonergic neurons. |
2013-08-02 |
2023-08-12 |
rat |
| Hidenori Aizawa, Shin Yanagihara, Megumi Kobayashi, Kazue Niisato, Takashi Takekawa, Rie Harukuni, Thomas J McHugh, Tomoki Fukai, Yoshikazu Isomura, Hitoshi Okamot. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678132. |
lateral habenula (lhb) has attracted growing interest as a regulator of serotonergic and dopaminergic neurons in the cns. |
2013-08-02 |
2023-08-12 |
rat |
| René Bernard, Rüdiger W Ve. Individual neurons in the rat lateral habenular complex project mostly to the dopaminergic ventral tegmental area or to the serotonergic raphe nuclei. The Journal of comparative neurology. vol 520. issue 11. 2012-09-28. PMID:22492391. |
the modulatory role of the lhb is partially assumed by putative spontaneously active lhb neurons projecting to the dopaminergic ventral tegmental area (vta) and to the serotonergic median (mnr) and dorsal raphe nuclei (dr). |
2012-09-28 |
2023-08-12 |
rat |
| René Bernard, Rüdiger W Ve. Individual neurons in the rat lateral habenular complex project mostly to the dopaminergic ventral tegmental area or to the serotonergic raphe nuclei. The Journal of comparative neurology. vol 520. issue 11. 2012-09-28. PMID:22492391. |
our results show that 1) the distribution of neurons in the lhb projecting to the three monoamine nuclei is similar and exhibits a great overlap, 2) the vast majority of lhb projection neurons target one monoaminergic nucleus only, and 3) very few, heterogeneously distributed lhb neurons project to both dopaminergic and serotonergic nuclei. |
2012-09-28 |
2023-08-12 |
rat |
| W C Poller, R Bernard, C Derst, T Weiss, V I Madai, R W Ve. Lateral habenular neurons projecting to reward-processing monoaminergic nuclei express hyperpolarization-activated cyclic nucleotid-gated cation channels. Neuroscience. vol 193. 2012-01-18. PMID:21798320. |
major projections of lhb neurons target the dopaminergic ventral tegmental area (vta) and the serotonergic dorsal (dr) and median raphe nuclei (mnr). |
2012-01-18 |
2023-08-12 |
rat |
| T R de Jong, K R Measor, M Chauke, B N Harris, W Saltzma. Brief pup exposure induces Fos expression in the lateral habenula and serotonergic caudal dorsal raphe nucleus of paternally experienced male California mice (Peromyscus californicus). Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20547210. |
pup exposure did, however, significantly increase fos-lir in the lateral habenula (lhb) and in predominantly serotonergic neurons in the caudal dorsal raphe nucleus (drc), as compared to pebble exposure. |
2010-12-16 |
2023-08-12 |
mouse |
| Roger Luis Henschel Pobbe, Helio Zangross. The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matter. Neuroscience letters. vol 479. issue 2. 2010-09-27. PMID:20478359. |
chemical stimulation of the lateral nucleus of the habenula (lhb), an area implicated in the regulation of serotonergic activity in raphe nuclei, affects the acquisition of inhibitory avoidance and escape expression of rats submitted to the elevated t-maze test of anxiety. |
2010-09-27 |
2023-08-12 |
rat |
| Simon Hong, Okihide Hikosak. The globus pallidus sends reward-related signals to the lateral habenula. Neuron. vol 60. issue 4. 2009-01-16. PMID:19038227. |
these results suggest that gpi may initiate reward-related signals through its effects on the lhb, which then influences the dopaminergic and serotonergic systems. |
2009-01-16 |
2023-08-12 |
monkey |
| P Kalén, O Lindvall, A Björklun. Electrical stimulation of the lateral habenula increases hippocampal noradrenaline release as monitored by in vivo microdialysis. Experimental brain research. vol 76. issue 1. 1989-08-31. PMID:2753106. |
since the lhb has previously been shown to be a powerful activator of the mesencephalic raphe nuclei we tested whether the effect was mediated via the serotonergic system. |
1989-08-31 |
2023-08-11 |
rat |