| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Creutzfeldt, R Ebert, B Willms, H Frerichs, J C Brow. Gastric inhibitory polypeptide (GIP) and insulin in obesity: increased response to stimulation and defective feedback control of serum levels. Diabetologia. vol 14. issue 1. 1978-04-26. PMID:627329. |
gastric inhibitory polypeptide (gip) and insulin in obesity: increased response to stimulation and defective feedback control of serum levels. |
1978-04-26 |
2023-08-11 |
Not clear |
| K R Sirinek, W G Pace, S E Crockett, T M O'Dorisio, E L Mazzaferri, S Catalan. Insulin-induced attenuation of glucose-stimulated gastric inhibitory polypeptide secretion. American journal of surgery. vol 135. issue 2. 1978-04-17. PMID:626287. |
administration of exogenous insulin before and after intraduodenal glucose results in blunting of the gip response to glucose. |
1978-04-17 |
2023-08-11 |
Not clear |
| K R Sirinek, W G Pace, S E Crockett, T M O'Dorisio, E L Mazzaferri, S Catalan. Insulin-induced attenuation of glucose-stimulated gastric inhibitory polypeptide secretion. American journal of surgery. vol 135. issue 2. 1978-04-17. PMID:626287. |
therefore, the present study suggests the existence of negative feedback regulation of gip release by endogenous insulin (pancreatico-gip axis). |
1978-04-17 |
2023-08-11 |
Not clear |
| W Schlegel, S Raptis, D Grube, E F Pfeiffe. Estimation of cholecystokinin-pancreozymin (CCK) in human plasma and tissue by a specific radioimmunoassay and the immunohistochemical identification of pancreozymin-producing cells in the duodenum of humans. Clinica chimica acta; international journal of clinical chemistry. vol 80. issue 2. 1977-12-29. PMID:562241. |
no significant crossreaction was found with gastrin, motilin, vasoactive polypeptide (vip), gastric inhibitory polypeptide (gip), natural and synthetic secretin, pancreatic glucagon or insulin. |
1977-12-29 |
2023-08-11 |
human |
| b' S A Ross, J C Brown, J Dupr\\xc3\\xa. Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus. Diabetes. vol 26. issue 6. 1977-07-23. PMID:324834.' |
the diabetics were nonobese and treated by diet alone; they exhibited exaggerated increments of plasma irgip in association with delayed and diminished peak increases in plasma immunoreactive insulin, suggesting relative failure of the beta-cell response to gip. |
1977-07-23 |
2023-08-11 |
human |
| b' S A Ross, J C Brown, J Dupr\\xc3\\xa. Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus. Diabetes. vol 26. issue 6. 1977-07-23. PMID:324834.' |
it is suggested that the defective beta-cell response may lead to diminished feedback inhibition of gip secretion by insulin in diabetes mellitus and that the glucagonotropic action of gip may be expressed under these conditions. |
1977-07-23 |
2023-08-11 |
human |
| T Taminato, Y Seino, Y Goto, Y Inoue, S Kadowak. Synthetic gastric inhibitory polypeptide. Stimulatory effect on insulin and glucagon secretion in the rat. Diabetes. vol 26. issue 5. 1977-06-22. PMID:323091. |
effect of synthetic gastric inhibitory polypeptide (gip) on insulin and glucagon secretion was stuied in vivo and in vitro in the rat. |
1977-06-22 |
2023-08-11 |
rat |
| T Taminato, Y Seino, Y Goto, Y Inoue, S Kadowak. Synthetic gastric inhibitory polypeptide. Stimulatory effect on insulin and glucagon secretion in the rat. Diabetes. vol 26. issue 5. 1977-06-22. PMID:323091. |
in in-vitro experiments with isolated pancreatic islets, gip significantly augmented insulin release induced by either 8.3 mm or 16.7 mm glucose, whereas the augmentation of glucagon release was observed at 3.3 mm, 8.3 mm, and 16.7 mm glucose concentrations. |
1977-06-22 |
2023-08-11 |
rat |
| T Taminato, Y Seino, Y Goto, Y Inoue, S Kadowak. Synthetic gastric inhibitory polypeptide. Stimulatory effect on insulin and glucagon secretion in the rat. Diabetes. vol 26. issue 5. 1977-06-22. PMID:323091. |
three peptides, consisting of 1-28, 22-43, and 15-43 amino acids of gip, failed to potentiate insulin and glucagon secretion. |
1977-06-22 |
2023-08-11 |
rat |
| T Taminato, Y Seino, Y Goto, Y Inoue, S Kadowak. Synthetic gastric inhibitory polypeptide. Stimulatory effect on insulin and glucagon secretion in the rat. Diabetes. vol 26. issue 5. 1977-06-22. PMID:323091. |
these results suggest that synthetic gip has a stimulating effect on insulin and glucagon secretion. |
1977-06-22 |
2023-08-11 |
rat |
| R Ebert, R Arnold, W Creutzfeld. Lowering of fasting and food stimulated serum immunoreactive gastric inhibitory polypeptide (GIP) by glucagon. Gut. vol 18. issue 2. 1977-06-22. PMID:856672. |
the effect of intravenous glucagon infusion on serum levels of immunoreactive gip (ir-gip), insulin (iri), gastrin (irg), and on blood glucose has been investigated in six healthy volunteers in the fasting state and during ingestion of a mixed standard meal. |
1977-06-22 |
2023-08-11 |
human |
| W Domschke, S Domschk. [New views on gastrointestinal hormones]. Fortschritte der Medizin. vol 95. issue 14. 1977-06-11. PMID:856699. |
gastric inhibitory polypeptide (gip) inhibits gastric secretion and motility (enterogastrone activity) and together with glucose it stimulates insulin release (incretin activity). |
1977-06-11 |
2023-08-11 |
Not clear |
| S E Crockett, E L Mazzaferri, S Catalan. Gastric inhibitory polypeptide (GIP) in maturity-onset diabetes mellitus. Diabetes. vol 25. issue 10. 1976-12-23. PMID:976601. |
serum gip, insulin, and glucose concentrations were determined during a standard oral glucose tolerance test in 80 individuals, 45 of whom were normal and 35 of whom had adult-onset diabetes mellitus according to usphs criteria. |
1976-12-23 |
2023-08-11 |
Not clear |
| S E Crockett, E L Mazzaferri, S Catalan. Gastric inhibitory polypeptide (GIP) in maturity-onset diabetes mellitus. Diabetes. vol 25. issue 10. 1976-12-23. PMID:976601. |
however, since our current understanding suggests the gip may be an important enteric signal for the release of insulin in man, and because gip has been shown to stimulate the release of immunoreactive glucagon, gip may play a role in the pathogenesis of diabetes mellitus. |
1976-12-23 |
2023-08-11 |
Not clear |
| R A Pederson, J C Brow. The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas. Endocrinology. vol 99. issue 3. 1976-10-29. PMID:954669. |
gastric inhibitory polypeptide (gip) produced a dose-related increase in immunoreactive insulin (iri) from the perfused isolated rat pancreas. |
1976-10-29 |
2023-08-11 |
rat |
| E F Pfeiffer, S Raptis, R Ziegle. [Interaction between gastrointestinal hormones and endocrine regulation]. Zeitschrift fur Gastroenterologie. vol 14 Suppl. 1976-10-20. PMID:8883. |
today we are mainly interested in the interaction between intermediary metabolism and incretory intestinal function; this is characterized by the joint action of conventional glandular hormones such as insulin and pancreatic glucagon as well as by the incretion of diffuse intestinal organs, hormones such as secretin, pancreozymin, motilin, vip and gip. |
1976-10-20 |
2023-08-11 |
human |
| E F Pfeiffer, S Raptis, R Ziegle. [Interaction between gastrointestinal hormones and endocrine regulation]. Zeitschrift fur Gastroenterologie. vol 14 Suppl. 1976-10-20. PMID:8883. |
gip ("gastric inhibitory peptide"), apart form acting upon the intestinal tract, also causes a marked rise in insulin production; this gip possibly is the factor responsible for the difference in glucose tolerance following i. v. or oral administration of glucose, something that scientists have been trying to discover for a long time. |
1976-10-20 |
2023-08-11 |
human |
| W Creutzfeldt, R Ebert, R Arnold, H Freichs, J C Brow. Gastric inhibitory polypeptide (GIP), gastrin and insulin: response to test meal in coeliac disease and after duodeno-pancreatectomy. Diabetologia. vol 12. issue 3. 1976-10-20. PMID:955338. |
gastric inhibitory polypeptide (gip), gastrin and insulin: response to test meal in coeliac disease and after duodeno-pancreatectomy. |
1976-10-20 |
2023-08-11 |
Not clear |
| S E Crockett, S Cataland, J M Falko, E L Mazzaferr. The insulinotropic effect of endogenous gastric inhibitory polypeptide in normal subjects. The Journal of clinical endocrinology and metabolism. vol 42. issue 6. 1976-08-23. PMID:932174. |
this study was designed to investigate the effects of simultaneous fat ingestion, a potent stimulus for gip release, and intravenous glucose infusion upon endogenous serum gip and insulin concentrations in normal subjects. |
1976-08-23 |
2023-08-11 |
human |
| S E Crockett, S Cataland, J M Falko, E L Mazzaferr. The insulinotropic effect of endogenous gastric inhibitory polypeptide in normal subjects. The Journal of clinical endocrinology and metabolism. vol 42. issue 6. 1976-08-23. PMID:932174. |
serum glucose, insulin (iri), and gip concentrations were measured at intervals between 15 and 180 minutes following each stimulus. |
1976-08-23 |
2023-08-11 |
human |