| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
cultured chicken hepatocytes were used to investigate whether insulin and gh interact to regulate insulin-like growth factor-i (igf-i) production in vitro. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
in the first set of experiments hepatocytes were preincubated for 6 h in hormone-free medium, and the effects of various combinations of insulin and gh on igf-i production over the next 24 h were quantified by radioimmunoassay. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
by insulin, 1.90 +/- 0.24-fold by gh and 4.46 +/- 0.68-fold by a combination of insulin and gh. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
these results demonstrate that insulin and gh interact synergistically to stimulate igf-i production in vitro. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
the synergism with gh occurred at physiological concentrations of insulin with half-maximal stimulation occurring at an insulin concentration of 6 ng/ml. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
in hepatocytes which had been exposed to insulin immediately before the start of the experiment, the presence of insulin was no longer required for maximal stimulation of igf-i production by gh. |
1991-05-15 |
2023-08-11 |
chicken |
| B Houston, I E O'Neil. Insulin and growth hormone act synergistically to stimulate insulin-like growth factor-I production by cultured chicken hepatocytes. The Journal of endocrinology. vol 128. issue 3. 1991-05-15. PMID:2013745. |
this in-vitro system will facilitate the study of the molecular basis of the interaction between insulin and gh. |
1991-05-15 |
2023-08-11 |
chicken |
| G W Kazmer, R H Oyle. Plasma growth hormone and insulin concentrations in, and free fatty acid release from adipose tissue cultured in vitro from Holstein cows of differing cow index during early and late lactation. Domestic animal endocrinology. vol 8. issue 1. 1991-05-10. PMID:2013227. |
early lactation cows averaged greater (p less than .05) daily milk production (33.4 vs 22.1 kg), greater (p less than .05) plasma growth hormone (gh) concentrations (3.9 vs 3.0 ng/ml) but lesser (p less than .01) insulin (ins) concentrations (.49 vs .73 ng/ml) than ll cows. |
1991-05-10 |
2023-08-11 |
cattle |
| P Tollet, B Enberg, A Mod. Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factor-I (IGF-I), and GH receptor messenger RNA expression in primary rat hepatocytes: a hormonal interplay with insulin, IGF-I, and thyroid hormone. Molecular endocrinology (Baltimore, Md.). vol 4. issue 12. 1991-05-07. PMID:2082191. |
growth hormone (gh) regulation of cytochrome p-450iic12, insulin-like growth factor-i (igf-i), and gh receptor messenger rna expression in primary rat hepatocytes: a hormonal interplay with insulin, igf-i, and thyroid hormone. |
1991-05-07 |
2023-08-11 |
rat |
| P Tollet, B Enberg, A Mod. Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factor-I (IGF-I), and GH receptor messenger RNA expression in primary rat hepatocytes: a hormonal interplay with insulin, IGF-I, and thyroid hormone. Molecular endocrinology (Baltimore, Md.). vol 4. issue 12. 1991-05-07. PMID:2082191. |
by investigating the effects of insulin, igf-i, t3, and corticosterone, alone or in combinations, in the presence or absence of gh we concluded that gh is indeed the inducer of p-450(15)beta mrna and igf-i mrna. |
1991-05-07 |
2023-08-11 |
rat |
| P Tollet, B Enberg, A Mod. Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factor-I (IGF-I), and GH receptor messenger RNA expression in primary rat hepatocytes: a hormonal interplay with insulin, IGF-I, and thyroid hormone. Molecular endocrinology (Baltimore, Md.). vol 4. issue 12. 1991-05-07. PMID:2082191. |
no significant effect of insulin was observed on ghr mrna expression, but a translational or posttranslational effect on ghr was seen, in that insulin increased the binding of gh to the cells 4-fold. |
1991-05-07 |
2023-08-11 |
rat |
| H M Payne-Robinson, J F Doherty, M H Golden, D T Simeo. The effect of DPT inoculation on the hormonal control of glucose homeostasis in children recovered from malnutrition. The West Indian medical journal. vol 39. issue 4. 1991-05-06. PMID:2082566. |
plasma insulin (ins), growth hormone (gh) and interleukin-1 (il-1) were measured by radioimmunoassay; plasma glucose (glu) by a glucose oxidase method; and red cell insulin binding (%sb) was determined, using a-14 monoiodinated insulin. |
1991-05-06 |
2023-08-11 |
Not clear |
| L S Phillips, J B Harp, S Goldstein, J Klein, C I Pa. Regulation and action of insulin-like growth factors at the cellular level. The Proceedings of the Nutrition Society. vol 49. issue 3. 1991-05-02. PMID:1964219. |
in the liver, the combined presence of gh, insulin, and critical metabolic fuels such as essential amino acids results in increased levels of igf-1 messenger rna, increased production of a high-mw igf-1 precursor, and increased release of igf-1 into the circulation, permitting action on distant target tissues bearing specific receptors for igf-1. |
1991-05-02 |
2023-08-11 |
Not clear |
| L S Phillips, J B Harp, S Goldstein, J Klein, C I Pa. Regulation and action of insulin-like growth factors at the cellular level. The Proceedings of the Nutrition Society. vol 49. issue 3. 1991-05-02. PMID:1964219. |
in extrahepatic tissues, both 'general' anabolic hormones (insulin and gh) as well as 'specific' hormones (e.g. |
1991-05-02 |
2023-08-11 |
Not clear |
| J Møller, J O Jørgensen, N Møller, K W Hansen, E B Pedersen, J S Christianse. Expansion of extracellular volume and suppression of atrial natriuretic peptide after growth hormone administration in normal man. The Journal of clinical endocrinology and metabolism. vol 72. issue 4. 1991-04-25. PMID:1826008. |
a significant gh induced increase in serum insulin growth factor i was observed. |
1991-04-25 |
2023-08-11 |
human |
| P G Campbell, T C Skaar, J R Vega, C R Baumrucke. Secretion of insulin-like growth factor-I (IGF-I) and IGF-binding proteins from bovine mammary tissue in vitro. The Journal of endocrinology. vol 128. issue 2. 1991-04-22. PMID:1706405. |
the addition of prolactin, insulin and cortisol, with or without gh, did not affect secretion of either igf-i or igfbp. |
1991-04-22 |
2023-08-11 |
human |
| D A Fryburg, R A Gelfand, E J Barret. Growth hormone acutely stimulates forearm muscle protein synthesis in normal humans. The American journal of physiology. vol 260. issue 3 Pt 1. 1991-04-12. PMID:2003602. |
forearm deep vein gh rose to 35 +/- 6 ng/ml in response to gh, whereas systemic levels of gh, insulin, and insulin-like growth factor i (igf-i) were unchanged. |
1991-04-12 |
2023-08-11 |
Not clear |
| D A Fryburg, R A Gelfand, E J Barret. Growth hormone acutely stimulates forearm muscle protein synthesis in normal humans. The American journal of physiology. vol 260. issue 3 Pt 1. 1991-04-12. PMID:2003602. |
in the absence of any change in systemic gh, igf-i, or insulin, these findings suggest that locally infused gh stimulates skeletal muscle protein synthesis. |
1991-04-12 |
2023-08-11 |
Not clear |
| P Roupas, S Y Chou, R J Towns, J L Kosty. Growth hormone inhibits activation of phosphatidylinositol phospholipase C in adipose plasma membranes: evidence for a growth hormone-induced change in G protein function. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 5. 1991-04-11. PMID:1848008. |
pituitary growth hormone (gh) functions physiologically to oppose the actions of insulin on carbohydrate and lipid metabolism by interfering with metabolic events that occur after insulin binds to its receptor. |
1991-04-11 |
2023-08-11 |
mouse |
| P Roupas, S Y Chou, R J Towns, J L Kosty. Growth hormone inhibits activation of phosphatidylinositol phospholipase C in adipose plasma membranes: evidence for a growth hormone-induced change in G protein function. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 5. 1991-04-11. PMID:1848008. |
recently, we found that insulin rapidly stimulates a phosphatidylinositol phospholipase c (pi-plc) in adipose tissue of obese (ob/ob) mice and that this effect of insulin is blocked by treatment of the animals with s-carboxymethylated human gh (rcm-hgh), a derivative having mainly anti-insulin activity. |
1991-04-11 |
2023-08-11 |
mouse |