| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Otani, H Nawashiro, N Nomura, S Fukui, N Tsuzuki, S Ishihara, K Shim. A role of glial fibrillary acidic protein in hippocampal degeneration after cerebral trauma or kainate-induced seizure. Acta neurochirurgica. Supplement. vol 86. 2004-03-09. PMID:14753450. |
however, little is known about the role of gfap in the hippocampal degeneration after brain injury. |
2004-03-09 |
2023-08-12 |
mouse |
| N Otani, H Nawashiro, N Nomura, S Fukui, N Tsuzuki, S Ishihara, K Shim. A role of glial fibrillary acidic protein in hippocampal degeneration after cerebral trauma or kainate-induced seizure. Acta neurochirurgica. Supplement. vol 86. 2004-03-09. PMID:14753450. |
these results indicate that gfap plays a crucial role in the hippocampal neurodegeneration after cns insult. |
2004-03-09 |
2023-08-12 |
mouse |
| Suzana Braga-de-Souza, Roberto Len. Temporal and spatial regulation of chondroitin sulfate, radial glial cells, growing commissural axons, and other hippocampal efferents in developing hamsters. The Journal of comparative neurology. vol 468. issue 2. 2004-02-10. PMID:14648681. |
developing hamster brains from embryonic day (e) 13 to postnatal day (p) 7 had 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (dii) crystals implanted into the hippocampus or were processed for fluorescent immunohistochemistry against chondroitin sulfate (cs) glycosaminoglycans and glial fibrillary acidic protein (gfap). |
2004-02-10 |
2023-08-12 |
Not clear |
| A Abdel-Rahman, Suzanne Abou-Donia, Eman El-Masry, Ashok Shetty, Mohamed Abou-Doni. Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum. Journal of toxicology and environmental health. Part A. vol 67. issue 2. 2004-02-04. PMID:14675905. |
these alterations were associated with significant neuronal cell death, reduced microtubule-associated protein (map-2) expression, and increased glial fibrillary acidic protein (gfap) expression in the cerebral cortex and the hippocampal subfields ca1 and ca3. |
2004-02-04 |
2023-08-12 |
rat |
| Beth A Luellen, Diane B Miller, Angela C Chisnell, Dennis L Murphy, James P O'Callaghan, Anne Milasincic Andrew. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14561848. |
striatal da was decreased to 60 to 80% of control during the first 48 h but returned to normal by 72 h. reactive gliosis, which occurs in response to neurodegeneration was not evident by immunocytochemistry but was detected by enzyme-linked immunosorbent assay, where glial fibrillary acidic protein (gfap) was increased to 130% of control in cortex, hippocampus, and brain stem 48 to 72 h post-treatment. |
2004-01-29 |
2023-08-12 |
mouse |
| Beth A Luellen, Diane B Miller, Angela C Chisnell, Dennis L Murphy, James P O'Callaghan, Anne Milasincic Andrew. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14561848. |
thus, 2'-nh2-mptp causes severe and immediate decrements in 5-ht and ne in frontal cortex and hippocampus, yet induces a modest gfap response compared with other mptp analogs that have their primary effect on da. |
2004-01-29 |
2023-08-12 |
mouse |
| Minoru Fujiki, Hidenori Kobayashi, Tatsuya Abe, Keisuke Ishi. Astroglial activation accompanies heat shock protein upregulation in rat brain following single oral dose of geranylgeranylacetone. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575900. |
the present study evaluated the consequences of oral gga on astrocytic activation and the expression of hsp and revealed that a single oral dose caused a transient increase in the immunoreactivity (ir) of hsp70 and glial fibrillary acidic protein (gfap) in the hippocampus of the rat brain. |
2004-01-22 |
2023-08-12 |
rat |
| Jee-Ching Hsu, Ying-Shiung Lee, Chen-Nen Chang, Huo-Li Chuang, Eng-Ang Ling, Chyn-Tair La. Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus. Cells, tissues, organs. vol 173. issue 4. 2004-01-08. PMID:12766354. |
western blots of hippocampal tissues corroborated the above-mentioned morphological findings in that expression of no-synthase (nos) was decreased while that of ox-42 and gfap was increased in the sleep-deprived rats. |
2004-01-08 |
2023-08-12 |
rat |
| Z Soltys, K Janeczko, O Orzyłowska-Sliwińska, M Zaremba, S Januszewski, B Oderfeld-Nowa. Morphological transformations of cells immunopositive for GFAP, TrkA or p75 in the CA1 hippocampal area following transient global ischemia in the rat. A quantitative study. Brain research. vol 987. issue 2. 2003-12-12. PMID:14499962. |
morphological transformations of cells immunopositive for gfap, trka or p75 in the ca1 hippocampal area following transient global ischemia in the rat. |
2003-12-12 |
2023-08-12 |
rat |
| Z Soltys, K Janeczko, O Orzyłowska-Sliwińska, M Zaremba, S Januszewski, B Oderfeld-Nowa. Morphological transformations of cells immunopositive for GFAP, TrkA or p75 in the CA1 hippocampal area following transient global ischemia in the rat. A quantitative study. Brain research. vol 987. issue 2. 2003-12-12. PMID:14499962. |
in the presented study, we analyzed quantitatively the morphological transformations of cells immunopositive for gfap or ngf receptors in the stratum radiatum of the ca1 hippocampal area in different survival periods after ischemia, evoked by 10-min cardiac arrest in adult rats. |
2003-12-12 |
2023-08-12 |
rat |
| D Champagne, D Pearson, D Dea, J Rochford, J Poirie. The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946703. |
specifically, we examined the effects of probucol on apoe production and its receptors (low density lipoprotein receptor [ldlr] and low density lipoprotein receptor-related protein [lrp]), astroglial marker of cell damage (glial fibrillary acidic protein [gfap]), markers of neuronal synaptic plasticity and integrity (synaptosomal associated protein of 25 kda [snap-25] and synaptophysin) as well as cholesterol biosynthesis (3-hydroxy-3-methylglutaryl coenzyme a reductase [hmgcoar]) in the hippocampus. |
2003-12-05 |
2023-08-12 |
human |
| Y Ikegami, S Goodenough, Y Inoue, P R Dodd, P A Wilce, I Matsumot. Increased TUNEL positive cells in human alcoholic brains. Neuroscience letters. vol 349. issue 3. 2003-12-04. PMID:12951203. |
seven out of eleven alcoholics exhibited tunel-positive cells in both superior frontal cortex and hippocampus, which were co-localized with gfap immunoreactivity. |
2003-12-04 |
2023-08-12 |
human |
| Neelima B Chauhan, Terry Lichtor, George J Siege. Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus. Brain research. vol 982. issue 2. 2003-12-01. PMID:12915257. |
3- and 24-month-old wild-type mice received juxta-amygdala injection of abeta42 and hippocampal sections were analyzed for glial fibrillary acidic protein (gfap)- and snap-25-ir at intervals after injections. |
2003-12-01 |
2023-08-12 |
mouse |
| Kun Zou, Daesung Kim, Atsuko Kakio, Kyunghee Byun, Jian-Sheng Gong, Jaewoo Kim, Myeungju Kim, Naoya Sawamura, Sei-ichi Nishimoto, Katsumi Matsuzaki, Bonghee Lee, Katsuhiko Yanagisawa, Makoto Michikaw. Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535944. |
abeta1-42 injection into the rat entorhinal cortex (ec) caused the hyperphosphorylation of tau on both sides of ec and hippocampus and increased the number of glial fibrillary acidic protein (gfap)-positive astrocytes in the ipsilateral ec, which were prevented by the concurrent injection of abeta1-40. |
2003-11-24 |
2023-08-12 |
rat |
| Ali Abdel-Rahman, Anjelika Dechkovskaia, Heena Mehta-Simmons, Xiangrong Guan, Wasiuddin Khan, Mohamed Abou-Doni. Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. Journal of toxicology and environmental health. Part A. vol 66. issue 21. 2003-11-18. PMID:14555401. |
a rise in glial fibrillary acidic protein (gfap) immunostaining was observed in the ca1 subfield of hippocampus and cerebellum on pnd 30 in female and male offspring of mothers treated with either nicotine or nicotine in combination with chlorpyrifos, but to a lesser extent in males. |
2003-11-18 |
2023-08-12 |
rat |
| Ali Abdel-Rahman, Anjelika Dechkovskaia, Heena Mehta-Simmons, Xiangrong Guan, Wasiuddin Khan, Mohamed Abou-Doni. Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. Journal of toxicology and environmental health. Part A. vol 66. issue 21. 2003-11-18. PMID:14555401. |
data suggest that maternal exposure to nicotine and chlorpyrifos, alone or in combination, produces differential alterations in brain regional ache activity and expression of gfap in cerebellum and hippocampus in offspring on pnd 30. |
2003-11-18 |
2023-08-12 |
rat |
| Ya-Ping Lu, Mei Zeng, Xiang-You Hu, Hao Xu, Dick F Swaab, Rivka Ravid, Jiang-Ning Zho. Estrogen receptor alpha-immunoreactive astrocytes are increased in the hippocampus in Alzheimer's disease. Experimental neurology. vol 183. issue 2. 2003-10-31. PMID:14552888. |
eralpha immunoreactivity was observed in neurons and glial fibrillary acidic protein (gfap)-immunoreactive astrocytes in the hippocampus both in controls and ad cases. |
2003-10-31 |
2023-08-12 |
human |
| Alicia A Babcock, William A Kuziel, Serge Rivest, Trevor Owen. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 21. 2003-09-16. PMID:12944523. |
in situ hybridization combined with immunohistochemistry for ionized binding calcium adapter molecule (iba)1 or glial fibrillary acidic protein (gfap) identified iba1+ microglia and gfap+ astrocytes as major sources of mcp-1/ccl2 within the lesion-reactive hippocampus. |
2003-09-16 |
2023-08-12 |
mouse |
| Vitali Filippov, Golo Kronenberg, Tatjyana Pivneva, Katja Reuter, Barbara Steiner, Li Ping Wang, Masahiro Yamaguchi, Helmut Kettenmann, Gerd Kemperman. Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Molecular and cellular neurosciences. vol 23. issue 3. 2003-09-11. PMID:12837622. |
based on the expression of glial fibrillary acidic protein (gfap), a recent hypothesis considered stem or progenitor cells in the adult hippocampus to be a type of astrocyte. |
2003-09-11 |
2023-08-12 |
mouse |
| R C MacPhail, J P O'Callaghan, J Coh. Acquisition, steady-state performance, and the effects of trimethyltin on the operant behavior and hippocampal GFAP of Long-Evans and Fischer 344 rats. Neurotoxicology and teratology. vol 25. issue 4. 2003-07-28. PMID:12798965. |
acquisition, steady-state performance, and the effects of trimethyltin on the operant behavior and hippocampal gfap of long-evans and fischer 344 rats. |
2003-07-28 |
2023-08-12 |
rat |