Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Anne-Maj Samuelsson, Eva Jennische, Hans-Arne Hansson, Agneta Holmän. Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABA(A) dysregulation and impaired spatial learning. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 5. 2006-05-31. PMID:16357100. |
because the hippocampus is a key area for learning and memory, we evaluated 4- and 24-wk-old rats for the effects of early and late prenatal exposure to interleukin-6 (il-6) on hippocampal morphology, expression of mrna for il-6, the gamma-aminobutyric acid receptor (gaba(aalpha5)), the nr1 subunit of the n-methyl-d-aspartate receptor, and glial fibrillary acidic protein (gfap), caspase-3 protein and mrna levels, and learning abilities. |
2006-05-31 |
2023-08-12 |
rat |
Beth A Luellen, Matthew E Szapacs, Christopher K Materese, Anne M Andrew. The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF. Neuropharmacology. vol 50. issue 3. 2006-05-24. PMID:16288930. |
1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-nh2-mptp) causes long-term depletions in cortical and hippocampal serotonin (5-ht) and norepinephrine (ne) that are accompanied by acute elevations in glial fibrillary acidic protein (gfap) and argyrophilia. |
2006-05-24 |
2023-08-12 |
mouse |
G Baydas, M Ozer, A Yasar, S T Koz, M Tuzc. Melatonin prevents oxidative stress and inhibits reactive gliosis induced by hyperhomocysteinemia in rats. Biochemistry. Biokhimiia. vol 71 Suppl 1. 2006-05-10. PMID:16487076. |
western blot analysis revealed an increase in glial fibrillary acidic protein (gfap) contents both in hippocampus and frontal cortex (p < 0.001) of hyperhomocysteinemic rats compared to the controls. |
2006-05-10 |
2023-08-12 |
rat |
G Baydas, M Ozer, A Yasar, S T Koz, M Tuzc. Melatonin prevents oxidative stress and inhibits reactive gliosis induced by hyperhomocysteinemia in rats. Biochemistry. Biokhimiia. vol 71 Suppl 1. 2006-05-10. PMID:16487076. |
administration of melatonin significantly decreased gfap contents in hippocampus and cortex (p < 0.05). |
2006-05-10 |
2023-08-12 |
rat |
B C Gray, P Skipp, V M O'Connor, V H Perr. Increased expression of glial fibrillary acidic protein fragments and mu-calpain activation within the hippocampus of prion-infected mice. Biochemical Society transactions. vol 34. issue Pt 1. 2006-03-27. PMID:16417481. |
using the intracerebrally injected me7 strain of prion agent to model disease, we identified an expected increase in gfap (glial fibrillary acidic protein) but additionally noted an accumulation of gfap cleavage fragments in hippocampal homogenates. |
2006-03-27 |
2023-08-12 |
mouse |
B C Gray, P Skipp, V M O'Connor, V H Perr. Increased expression of glial fibrillary acidic protein fragments and mu-calpain activation within the hippocampus of prion-infected mice. Biochemical Society transactions. vol 34. issue Pt 1. 2006-03-27. PMID:16417481. |
a time-dependent increase in hippocampal mu-calpain immunoreactivity within astrocytes suggests that its proteolytic activity may account for the cleavage of gfap that is observed in the me7 model. |
2006-03-27 |
2023-08-12 |
mouse |
M C Silva, J Rocha, C S Pires, L C Ribeiro, G Brolese, M C Leite, L M V Almeida, F Tramontina, D R Ziegler, C A Gonçalve. Transitory gliosis in the CA3 hippocampal region in rats fed on a ketogenic diet. Nutritional neuroscience. vol 8. issue 4. 2006-03-16. PMID:16491652. |
we found a transitory increment in gfap in the ca3 hippocampal region, but not in the ca1 or dentate gyrus (dg). |
2006-03-16 |
2023-08-12 |
rat |
Hyman M Schipper, David A Bennett, Adrienne Liberman, Julia L Bienias, Julie A Schneider, Jeremiah Kelly, Zoe Arvanitaki. Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment. Neurobiology of aging. vol 27. issue 2. 2006-03-14. PMID:16399210. |
oxidative stress was measured as the percentage of astrocytes expressing heme oxygenase-1 (ho-1) in post mortem temporal cortex and hippocampus after dual ho-1/glial fibrillary acidic protein (gfap) immunohistochemistry. |
2006-03-14 |
2023-08-12 |
Not clear |
Maria C Vanzani, Ruben F Iacono, Roberto L Caccuri, Maria I Berri. Immunochemical and morphometric features of astrocyte reactivity vs. plaque location in Alzheimer's disease. Medicina. vol 65. issue 3. 2006-02-23. PMID:16042131. |
the quantitative relationship between glial fibrillary acidic protein (gfap) hyper-reactivity and beta-amyloid protein (betaap) deposition was investigated by double immunoperoxidase labeling of hippocampal and entorhinal cortex sections from five alzheimer's disease (ad) cases and five age-matched controls. |
2006-02-23 |
2023-08-12 |
Not clear |
Maria C Vanzani, Ruben F Iacono, Roberto L Caccuri, Maria I Berri. Immunochemical and morphometric features of astrocyte reactivity vs. plaque location in Alzheimer's disease. Medicina. vol 65. issue 3. 2006-02-23. PMID:16042131. |
in contrast, the mean number of gfap (+) cells was significantly greater in the hippocampus than in the entorhinal cortex from ad cases (49 vs.39). |
2006-02-23 |
2023-08-12 |
Not clear |
Maria C Vanzani, Ruben F Iacono, Roberto L Caccuri, Maria I Berri. Immunochemical and morphometric features of astrocyte reactivity vs. plaque location in Alzheimer's disease. Medicina. vol 65. issue 3. 2006-02-23. PMID:16042131. |
since an increased number of gfap (+) cells in the hippocampus was not accompanied by an increased number and/or perimeter of neighbouring plaques, such differential hyper-reactivity in samples from ad patients, as well as in those with normal aging, seems to depend partially on the regional location of the involved astrocyte. |
2006-02-23 |
2023-08-12 |
Not clear |
Mary E McAsey, Craig Cady, Lindsay M Jackson, Miao Li, Shari Randall, Britto P Nathan, Robert G Strubl. Time course of response to estradiol replacement in ovariectomized mice: brain apolipoprotein E and synaptophysin transiently increase and glial fibrillary acidic protein is suppressed. Experimental neurology. vol 197. issue 1. 2006-02-08. PMID:16226751. |
western blotting of homogenates from somatosensory cortex, hippocampus, olfactory bulb and cerebellum was performed to obtain concentrations of glial fibrillary acidic protein (gfap), apolipoprotein e (apoe) and synaptophysin (syn). |
2006-02-08 |
2023-08-12 |
mouse |
Cíntia Eickhoff Battú, Graça F R S Godinho, Ana Paula Thomazi, Lúcia M V de Almeida, Carlos Alberto Gonçalves, Trícia Kommers, Susana T Wofchu. Ontogenetic changes in glial fibrillary acid protein phosphorylation, glutamate uptake and glutamine synthetase activity in olfactory bulb of rats. Neurochemical research. vol 30. issue 9. 2006-02-06. PMID:16292502. |
phosphorylation of the glial fibrillary acidic protein (gfap) in hippocampal and cerebellar slices from immature rats is stimulated by glutamate. |
2006-02-06 |
2023-08-12 |
rat |
Han Kyu Lee, Young Jun Seo, Seong Soo Choi, Min Soo Kwon, Eon Jeong Shim, Jin Young Lee, Hong Won Su. Role of gamma-aminobutyricacidB(GABA(B)) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus. Experimental & molecular medicine. vol 37. issue 6. 2006-02-01. PMID:16391514. |
ka increased the phosphorylated extracellular signal-regulated kinase (p-erk) and ca(2+)/calmodulin-dependent protein kinase ii (p-camk ii) immunoreactivities (irs) 30 min after ka treatment, and c-fos, c-jun ir 2 h, and glial fibrillary acidic protein (gfap), complement receptor type 3 (ox-42) ir 1 day in hippocampal area in ka-injected mice. |
2006-02-01 |
2023-08-12 |
mouse |
Han Kyu Lee, Young Jun Seo, Seong Soo Choi, Min Soo Kwon, Eon Jeong Shim, Jin Young Lee, Hong Won Su. Role of gamma-aminobutyricacidB(GABA(B)) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus. Experimental & molecular medicine. vol 37. issue 6. 2006-02-01. PMID:16391514. |
activated astrocytes, which was presented by gfap ir, and activated microglia, which was presented by the ox-42 ir, may be a good indicator for measuring the cell death in hippocampal regions by ka excitotoxicity. |
2006-02-01 |
2023-08-12 |
mouse |
Ronald Jabs, Tatjana Pivneva, Kerstin Hüttmann, Alexandra Wyczynski, Christiane Nolte, Helmut Kettenmann, Christian Steinhäuse. Synaptic transmission onto hippocampal glial cells with hGFAP promoter activity. Journal of cell science. vol 118. issue Pt 16. 2006-01-24. PMID:16076898. |
using transgenic mice expressing green fluorescent protein (egfp) under the control of the human gfap promoter, we tested for synaptic input to identified glial cells in the hippocampus. |
2006-01-24 |
2023-08-12 |
mouse |
Tian-Ming Yuan, Hui-Min Yu, Wei-Zhong Gu, Jian-Ping L. White matter damage and chemokine induction in developing rat brain after intrauterine infection. Journal of perinatal medicine. vol 33. issue 5. 2005-12-12. PMID:16238536. |
the numbers of gfap-positive cells of the e. coli-treated group pups were marked increased in periventricular white matter and hippocampus at p7 compared with the control group but no significant different levels of gfap expression in corpus callosum were found between two groups. |
2005-12-12 |
2023-08-12 |
rat |
Graciela Beatriz Garcia, Maria Eugenia Biancardi, Ariel Dario Quirog. Vanadium (V)-induced neurotoxicity in the rat central nervous system: a histo-immunohistochemical study. Drug and chemical toxicology. vol 28. issue 3. 2005-11-21. PMID:16051558. |
gfap and s-100 immunohistochemistry showed enlarged astrocytes in cerebellum and hippocampus in the v(+5)-exposed animals. |
2005-11-21 |
2023-08-12 |
rat |
M Mahiuddin Ahmed, Mohammad Arif, Toshiyuki Chikuma, Takeshi Kat. Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment. Neurochemistry international. vol 47. issue 4. 2005-09-08. PMID:15985312. |
the expression of gfap and cd11b immunohistochemically increased in the hippocampus of the ptz-treated rat as compared with controls. |
2005-09-08 |
2023-08-12 |
rat |
Tushar D Patel, Feng C Zho. Ontogeny of 5-HT1A receptor expression in the developing hippocampus. Brain research. Developmental brain research. vol 157. issue 1. 2005-08-12. PMID:15939084. |
in addition to postmitotic neurons, we have observed that s100 and gfap positive glia transiently express 5ht1a during early postnatal development of the hippocampus. |
2005-08-12 |
2023-08-12 |
rat |