All Relations between gfap and hippocampus

Publication Sentence Publish Date Extraction Date Species
Dayanne Terra Tenório Nonato, Gislei Frota Aragão, Raquel Magalhães Castelo Branco Craveiro, Maria Gonçalves Pereira, Silvânia Maria Mendes Vasconcelos, Deysi Viviana Tenazoa Wong, Roberto César Pereira Lima Júnior, Pedro Marcos Gomes Soares, Marcos Aurélio de Sousa Lima, Ana Maria Sampaio Assreuy, Edna Maria Camelo Chave. Polysaccharide-rich extract of Genipa americana leaves protects seizures and oxidative stress in the mice model of pentylenetetrazole-induced epilepsy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364734. ptz increased glial fibrillar acid proteins (gfap) and iba-1 in hippocampus, which was reversed by pre-ga (gfap: 1.9 ± 0.23 vs ptz: 3.1 ± 1.3 and iba-1: 2.2 ± 0.8 vs ptz: 3.2 ± 1.4). 2024-02-16 2024-02-19 mouse
V R Varma, Y An, P R Kac, M Bilgel, A Moghekar, T Loeffler, D Amschl, J Troncoso, K Blennow, H Zetterberg, N J Ashton, S M Resnick, M Thambisett. Longitudinal progression of blood biomarkers reveals a key role of astrocyte reactivity in preclinical Alzheimer's disease. medRxiv : the preprint server for health sciences. 2024-02-12. PMID:38343809. in the 5xfad transgenic model of ad, we observed greater gfap levels in the cortex and hippocampus of transgenic mice relative to wild-type prior to the development of cognitive impairment. 2024-02-12 2024-02-15 mouse
Grigorios Kyriatzis, Anne Bernard, Angélique Bôle, Michel Khrestchatisky, Lotfi Ferha. In the Rat Hippocampus, Pilocarpine-Induced Status Epilepticus Is Associated with Reactive Glia and Concomitant Increased Expression of CD31, PDGFRβ, and Collagen IV in Endothelial Cells and Pericytes of the Blood-Brain Barrier. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338969. in the hippocampus, increased expression of mrna encoding the glial proteins gfap and iba1 confirmed neuroinflammatory status. 2024-02-10 2024-02-12 rat
Patrycja Kupnicka, Joanna Listos, Maciej Tarnowski, Agnieszka Kolasa, Patrycja Kapczuk, Anna Surówka, Jakub Kwiatkowski, Kamil Janawa, Dariusz Chlubek, Irena Baranowska-Bosiack. The Effect of Prenatal and Neonatal Fluoride Exposure to Morphine-Induced Neuroinflammation. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255899. we provide evidence that both morphine administration and fluoride exposure have an impact on the inflammatory response by altering the expression of cox-1, cox-2, ionized calcium-binding adapter molecule (iba1), and glial fibrillary acidic protein (gfap) in brain structures involved in dependence development, such as the prefrontal cortex, striatum, hippocampus, and cerebellum. 2024-01-23 2024-01-25 rat
Ting Zhan, Shanshan Tang, Junpei Du, Jingshuang Liu, Bodong Yu, Yuxin Yang, Yuting Xie, Yanting Qiu, Guodong Li, Yun Ga. Implication of lncRNA MSTRG.81401 in Hippocampal Pyroptosis Induced by P2X7 Receptor in Type 2 Diabetic Rats with Neuropathic Pain Combined with Depression. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256257. in the dnp + mdd rats, elevated levels in hippocampal p2x7 receptor mrna and protein were observed, along with increased co-expression of p2x7 and the astrocytic marker glial fibrillary acidic protein (gfap). 2024-01-23 2024-01-25 rat
Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong B. Innovative Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging and Its Utility in Whole-Brain Visualization. ACS omega. vol 9. issue 2. 2024-01-22. PMID:38250363. based on the assessment of glial cell responses in the hippocampus and neocortex regions using gfap and iba1 biomarkers, cy5-peg2 seems to have minimal adverse effects on brain immune response or neuronal health. 2024-01-22 2024-01-24 Not clear
Jiang-Ping Wei, Zi-Xuan Zhao, Jing Zeng, Fang-Hong Shang, Lei Hua, Yong Yang, Xiao-Mei Zhan. [Yigong Powder regulates CXCL12/CXCR4 signaling to reduce glutamate release and prevent cognitive decline in mouse model of aging]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 23. 2024-01-11. PMID:38212005. the immunofluorescence assay was employed to detect the expression of ionized calcium-binding adapter molecule 1(iba1), glial fibrillary acidic protein(gfap), chemokine c-x-c-motif ligand 12(cxcl12), chemokine c-x-c-motif receptor 4(cxcr4) in the hippocampus and observe the positional relationship between iba1, gfap, and cxcr4. 2024-01-11 2024-01-14 mouse
Xue Wang, Xiaomei Fu, Xiurong Luo, Yiyi Lai, Chuipu Cai, Yanfang Liao, Zhao Dai, Shuhuan Fang, Jiansong Fan. Network Proximity Analysis Deciphers the Pharmacological Mechanism of Osthole against D-Galactose Induced Cognitive Disorder in Rats. Molecules (Basel, Switzerland). vol 29. issue 1. 2024-01-11. PMID:38202603. among them, the pro-apoptotic markers (bax), anti-apoptotic protein (bcl-2), the microgliosis (iba-1), astro-cytosis (gfap), and inflammatory cytokines (tnf-r1) were evaluated in both hippocampus and cortex. 2024-01-11 2024-01-13 rat
Xiaonan Wang, Fuping Zhang, Le Niu, Junni Yan, Huanhuan Liu, Di Wang, Juan Hui, Haiyue Dai, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity. Journal of affective disorders. 2023-12-30. PMID:38159655. moreover, rtms ameliorated the reduction in gfap and glt-1 expression, alleviated the decrease in bdnf, psd95 and synapsin-1 expression, also reversed the expression levels of bax and bcl2 in the hippocampus of cums-induced rats. 2023-12-30 2024-01-05 rat
Nan Yan, Zhengdong Wang, Zhou Li, Yang Zheng, Nan Chang, Kangjie Xu, Qian Wang, Xiaoxu Dua. Arsenic Exposure Induces Neuro-immune Toxicity in the Cerebral Cortex and the Hippocampus via Neuroglia and NLRP3 Inflammasome Activation in C57BL/6 Mice. Biological trace element research. 2023-12-26. PMID:38148432. in addition, immunofluorescence staining showed that 25 and 50 mg/l arsenic all increased the expression of cd11b and glial fibrillary acidic protein (gfap) in the cerebral cortex and hippocampus (p < 0.05). 2023-12-26 2023-12-29 mouse
Doodipala Samba Reddy, Tanveer Singh, Sreevidhya Ramakrishnan, Madeline Huber, Xin W. The Journal of pharmacology and experimental therapeutics. 2023-12-10. PMID:38071567. additionally, vx-treated animals exhibited a reduced inflammatory response with decreased gfap(+) astrogliosis and iba1(+) microgliosis in the hippocampus, amygdala, and other regions. 2023-12-10 2023-12-17 Not clear
Octavio Fabián Mercado-Gómez, Virginia Selene Arriaga-Ávila, Angélica Vega-García, Sandra Orozco-Suarez, Vadim Pérez-Koldenkova, Juan José Camarillo-Sánchez, Marcelino Álvarez-Herrera, Rosalinda Guevara-Guzmá. Daytime-Restricted Feeding Ameliorates Oxidative Stress by Increasing NRF2 Transcriptional Factor in the Rat Hippocampus in the Pilocarpine-Induced Acute Seizure Model. Brain sciences. vol 13. issue 10. 2023-10-30. PMID:37891811. the cellular distribution of the nrf2 and sod2 proteins in the pyramidal cell layer of both the ca1 and ca3 hippocampal subfields and astrocytes (gfap marker) were quantified using immunofluorescence and immunohistochemistry, respectively. 2023-10-30 2023-11-08 rat
Rehab Nady, Rasha R Ahmed, Nadia Moustafa, Manal Abdul-Hami. TNF-α blockage by etanercept restores spatial learning and reduces cellular degeneration in the hippocampus during liver cirrhosis. Tissue & cell. vol 85. 2023-10-21. PMID:37865039. the excised brains were also immunohistochemically stained with glial fibrillary acidic protein (gfap) to estimate both the number and integrity of hippocampal astrocytes. 2023-10-21 2023-11-08 rat
Gehua Wen, Xiaoni Zhan, Xiaoming Xu, Xi Xia, Shukun Jiang, Xinghua Ren, Weishu Ren, Haoyang Lou, Lei Lu, Anca Hermenean, Jun Yao, Lina Gao, Baoman Li, Yan Lu, Xu W. Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model. Molecular neurobiology. 2023-10-15. PMID:37840071. meanwhile, ketamine reduced the level of hippocampus nlrp3 and the expression of its downstream molecules in chronic unpredictable mild stress (cums) mice model by western blot and reduced the colocalization of gfap and gsdmd by nearly 25% via immunofluorescent staining. 2023-10-15 2023-11-08 mouse
Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and gfap in the hippocampus of chronically stressed rats in a sex-specific manner. 2023-10-05 2023-10-07 rat
Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. to this end, we studied possible alterations in hippocampal glial fibrillary acidic protein (gfap) and synaptophysin (syn) in cus rats previously housed in ee. 2023-10-05 2023-10-07 rat
Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. cus reduced the expression of syn in all hippocampal areas, whereas lower gfap expression was evident only in ca1 and ca3. 2023-10-05 2023-10-07 rat
Steffi De Meyer, Elena R Blujdea, Jolien Schaeverbeke, Mariska Reinartz, Emma S Luckett, Katarzyna Adamczuk, Koen Van Laere, Patrick Dupont, Charlotte E Teunissen, Rik Vandenberghe, Koen Poese. Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes. Brain : a journal of neurology. 2023-10-03. PMID:37787146. whole-brain voxelwise analyses revealed that low aβ1-42/aβ1-40 predicted aβ accumulation within the precuneus and frontal regions, high gfap and nfl predicted grey matter loss within hippocampal regions and low aβ1-42/aβ1-40 predicted grey matter loss in lateral temporal regions. 2023-10-03 2023-10-07 human
Guoquan Zhang, Qinghan Ren, Ying Lin, Dezheng Zhou, Li Huang, Wen Li, Hong Chang, Guowei Huang, Guowei Huang, Zhenshu Li, Jing Ya. Parental folic acid deficiency delays neurobehavioral development in rat offspring by inhibiting the differentiation of neural stem cells into neurons. The Journal of nutritional biochemistry. 2023-10-03. PMID:37788724. for in vivo study, neurobehavioral indexes, and neuron-specific nuclear protein (neun) and glial fibrillary acidic protein (gfap) expression in the brain hippocampus and cerebral cortex of offspring were measured at different time points. 2023-10-03 2023-10-07 rat
Courtney Cross, Maya Davies, Emma Bateman, Elise Crame, Paul Joyce, Anthony Wignall, Amin Ariaee, Marc Gladman, Hannah Wardill, Joanne M Bowe. Fibre-rich diet attenuates chemotherapy-related neuroinflammation in mice. Brain, behavior, and immunity. 2023-09-27. PMID:37757978. in the context of 5-fu, the diet reduced gfap expression in the ca1 region of the hippocampus (p < 0.0001) as well as the midbrain (p = 0.0216). 2023-09-27 2023-10-07 mouse