| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H A G Teive, E R Pereira, J A A Zavala, M C Lange, L de Paola, S Raskin, L C Werneck, T Hamada, J A McGrat. Generalized dystonia and striatal calcifications with lipoid proteinosis. Neurology. vol 63. issue 11. 2005-08-04. PMID:15596773. |
lp was recently mapped to the 1q21 locus and shown to result from mutations in the extracellular matrix protein 1 gene (ecm1). |
2005-08-04 |
2023-08-12 |
Not clear |
| Ien Chan, Andrew P South, John A McGrath, Noritaka Oyama, Balbir S Bhogal, Martin M Black, Takahiro Hamad. Rapid diagnosis of lipoid proteinosis using an anti-extracellular matrix protein 1 (ECM1) antibody. Journal of dermatological science. vol 35. issue 2. 2005-02-02. PMID:15265527. |
rapid diagnosis of lipoid proteinosis using an anti-extracellular matrix protein 1 (ecm1) antibody. |
2005-02-02 |
2023-08-12 |
Not clear |
| I Chan, N Oyama, S M Neill, F Wojnarowska, M M Black, J A McGrat. Characterization of IgG autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Clinical and experimental dermatology. vol 29. issue 5. 2004-12-30. PMID:15347336. |
indeed, circulating igg autoantibodies to the glycoprotein extracellular matrix protein 1 (ecm1) have been demonstrated in the sera of about 75% of affected individuals. |
2004-12-30 |
2023-08-12 |
Not clear |
| W Van Hougenhouck-Tulleken, I Chan, T Hamada, H Thornton, T Jenkins, W H I McLean, J A McGrath, M Ramsa. Clinical and molecular characterization of lipoid proteinosis in Namaqualand, South Africa. The British journal of dermatology. vol 151. issue 2. 2004-12-16. PMID:15327549. |
mutations within the extracellular matrix protein 1 (ecm1) gene cause lip. |
2004-12-16 |
2023-08-12 |
Not clear |
| Noritaka Oyama, Ien Chan, Sallie M Neill, Andrew P South, Fenella Wojnarowska, Yoshio Kawakami, David D'Cruz, Kirti Mepani, Graham J Hughes, Balbir S Bhogal, Fumio Kaneko, Martin M Black, John A McGrat. Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus. The Journal of clinical investigation. vol 113. issue 11. 2004-06-29. PMID:15173881. |
lichen sclerosus is a common, acquired chronic inflammatory skin disease of unknown etiology, although circulating autoantibodies to the glycoprotein extracellular matrix protein 1 (ecm1) have been detected in most patients' sera. |
2004-06-29 |
2023-08-12 |
human |
| Erwin Pauws, Geertruda J M Veenboer, Jan W A Smit, Jan J M de Vijlder, Hans Morreau, Carrie Ris-Stalper. Genes differentially expressed in thyroid carcinoma identified by comparison of SAGE expression profiles. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14715705. |
a tag coding for extracellular matrix protein 1 (ecm1) is absent in the normal thyroid sage library and present 55 times in the tumor. |
2004-06-01 |
2023-08-12 |
Not clear |
| I Cha. The role of extracellular matrix protein 1 in human skin. Clinical and experimental dermatology. vol 29. issue 1. 2004-03-01. PMID:14723723. |
extracellular matrix protein 1 (ecm1) was first identified in 1994 as an 85-kda glycoprotein secreted by a mouse osteogenic stromal cell line. |
2004-03-01 |
2023-08-12 |
mouse |
| Luping Wang, Jiyao Yu, Jian Ni, Xue-Ming Xu, Jianjin Wang, Haoyong Ning, Xu-Fang Pei, Jinguo Chen, Shanmin Yang, Charles B Underhill, Lei Liu, Joeri Liekens, Joseph Merregaert, Lurong Zhan. Extracellular matrix protein 1 (ECM1) is over-expressed in malignant epithelial tumors. Cancer letters. vol 200. issue 1. 2003-11-12. PMID:14550953. |
extracellular matrix protein 1 (ecm1) is over-expressed in malignant epithelial tumors. |
2003-11-12 |
2023-08-12 |
human |
| Luping Wang, Jiyao Yu, Jian Ni, Xue-Ming Xu, Jianjin Wang, Haoyong Ning, Xu-Fang Pei, Jinguo Chen, Shanmin Yang, Charles B Underhill, Lei Liu, Joeri Liekens, Joseph Merregaert, Lurong Zhan. Extracellular matrix protein 1 (ECM1) is over-expressed in malignant epithelial tumors. Cancer letters. vol 200. issue 1. 2003-11-12. PMID:14550953. |
the extracellular matrix protein 1 (ecm1) is a secreted protein that has been implicated with cell proliferation, angiogenesis and differentiation. |
2003-11-12 |
2023-08-12 |
human |
| I Chan, A El-Zurghany, B Zendah, M Benghazil, N Oyama, T Hamada, J A McGrat. Molecular basis of lipoid proteinosis in a Libyan family. Clinical and experimental dermatology. vol 28. issue 5. 2003-10-30. PMID:12950350. |
the disorder has recently been shown to result from loss-of-function mutations in the extracellular matrix protein 1 gene (ecm1) on 1q21. |
2003-10-30 |
2023-08-12 |
Not clear |
| Noritaka Oyama, Ien Chan, Sallie M Neill, Takahiro Hamada, Andrew P South, Vesarat Wessagowit, Fenella Wojnarowska, David D'Cruz, Graham J Hughes, Martin M Black, John A McGrat. Autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Lancet (London, England). vol 362. issue 9378. 2003-07-30. PMID:12867112. |
the clinicopathological similarities between lichen sclerosus and lipoid proteinosis, which results from mutations in extracellular matrix protein 1 (ecm1), suggest this protein as an autoantigen. |
2003-07-30 |
2023-08-12 |
Not clear |
| Maurizio Mongiat, Jian Fu, Rachel Oldershaw, Robert Greenhalgh, Allen M Gown, Renato V Iozz. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. The Journal of biological chemistry. vol 278. issue 19. 2003-06-30. PMID:12604605. |
perlecan protein core interacts with extracellular matrix protein 1 (ecm1), a glycoprotein involved in bone formation and angiogenesis. |
2003-06-30 |
2023-08-12 |
human |
| Maurizio Mongiat, Jian Fu, Rachel Oldershaw, Robert Greenhalgh, Allen M Gown, Renato V Iozz. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. The Journal of biological chemistry. vol 278. issue 19. 2003-06-30. PMID:12604605. |
among the strongest interacting clones, we isolated a approximately 1.6-kb cdna insert that encoded extracellular matrix protein 1 (ecm1), a secreted glycoprotein involved in bone formation and angiogenesis. |
2003-06-30 |
2023-08-12 |
human |
| Takahiro Hamada, Vesarat Wessagowit, Andrew P South, Gabrielle H S Ashton, Ien Chan, Noritaka Oyama, Apatorn Siriwattana, Prachiya Jewhasuchin, Somyot Charuwichitratana, Devinder M Thappa, Balasubramanian Jeevankumar, Patsy Lenane, Bernice Krafchik, Kanokvalai Kulthanan, Hiroshi Shimizu, Tamer I Kaya, Mehmet E Erdal, Mauro Paradisi, Amy S Paller, Mariko Seishima, Takashi Hashimoto, John A McGrat. Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation. The Journal of investigative dermatology. vol 120. issue 3. 2003-05-12. PMID:12603844. |
extracellular matrix protein 1 gene (ecm1) mutations in lipoid proteinosis and genotype-phenotype correlation. |
2003-05-12 |
2023-08-12 |
human |
| Takahiro Hamada, Vesarat Wessagowit, Andrew P South, Gabrielle H S Ashton, Ien Chan, Noritaka Oyama, Apatorn Siriwattana, Prachiya Jewhasuchin, Somyot Charuwichitratana, Devinder M Thappa, Balasubramanian Jeevankumar, Patsy Lenane, Bernice Krafchik, Kanokvalai Kulthanan, Hiroshi Shimizu, Tamer I Kaya, Mehmet E Erdal, Mauro Paradisi, Amy S Paller, Mariko Seishima, Takashi Hashimoto, John A McGrat. Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation. The Journal of investigative dermatology. vol 120. issue 3. 2003-05-12. PMID:12603844. |
the autosomal recessive disorder lipoid proteinosis results from mutations in extracellular matrix protein 1 (ecm1), a glycoprotein expressed in several tissues (including skin) and composed of two alternatively spliced isoforms, ecm1a and ecm1b, the latter lacking exon 7 of this 10-exon gene (ecm1). |
2003-05-12 |
2023-08-12 |
human |
| T Hamad. Lipoid proteinosis. Clinical and experimental dermatology. vol 27. issue 8. 2003-03-19. PMID:12472532. |
recently, lipoid proteinosis was mapped to 1q21 and pathogenetic loss-of-function mutations were identified in the extracellular matrix protein 1 gene (ecm1). |
2003-03-19 |
2023-08-12 |
Not clear |
| Takahiro Hamada, W H Irwin McLean, Michele Ramsay, Gabrielle H S Ashton, Arti Nanda, Trefor Jenkins, Isobel Edelstein, Andrew P South, Oliver Bleck, Vesarat Wessagowit, Rajeev Mallipeddi, Guy E Orchard, Hong Wan, Patricia J C Dopping-Hepenstal, Jemima E Mellerio, Neil V Whittock, Colin S Munro, Maurice A M van Steensel, Peter M Steijlen, Jian Ni, Lurong Zhang, Takashi Hashimoto, Robin A J Eady, John A McGrat. Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1). Human molecular genetics. vol 11. issue 7. 2002-09-11. PMID:11929856. |
lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ecm1). |
2002-09-11 |
2023-08-12 |
Not clear |
| Takahiro Hamada, W H Irwin McLean, Michele Ramsay, Gabrielle H S Ashton, Arti Nanda, Trefor Jenkins, Isobel Edelstein, Andrew P South, Oliver Bleck, Vesarat Wessagowit, Rajeev Mallipeddi, Guy E Orchard, Hong Wan, Patricia J C Dopping-Hepenstal, Jemima E Mellerio, Neil V Whittock, Colin S Munro, Maurice A M van Steensel, Peter M Steijlen, Jian Ni, Lurong Zhang, Takashi Hashimoto, Robin A J Eady, John A McGrat. Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1). Human molecular genetics. vol 11. issue 7. 2002-09-11. PMID:11929856. |
using a candidate gene approach (comparison of control versus lp gene expression in cultured fibroblasts) and subsequent direct sequencing of genomic dna, we identified six different homozygous loss-of-function mutations in the extracellular matrix protein 1 gene (ecm1). |
2002-09-11 |
2023-08-12 |
Not clear |
| M M Deckers, P Smits, M Karperien, J Ni, P Tylzanowski, P Feng, D Parmelee, J Zhang, E Bouffard, R Gentz, C W Löwik, J Merregaer. Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro. Bone. vol 28. issue 1. 2001-06-07. PMID:11165938. |
two mrnas are transcribed from the extracellular matrix protein 1 gene (ecm1): ecm1a and an alternatively spliced ecm1b. |
2001-06-07 |
2023-08-12 |
mouse |
| Z Han, J Ni, P Smits, C B Underhill, B Xie, Y Chen, N Liu, P Tylzanowski, D Parmelee, P Feng, I Ding, F Gao, R Gentz, D Huylebroeck, J Merregaert, L Zhan. Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 6. 2001-05-10. PMID:11292659. |
extracellular matrix protein 1 (ecm1) has angiogenic properties and is expressed by breast tumor cells. |
2001-05-10 |
2023-08-12 |
mouse |