| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Geeta Lal, Lakshmi Padmanabha, Rachael Nicholson, Brian J Smith, Lurong Zhang, James R Howe, Robert A Robinson, M Sue O'Dorisi. ECM1 expression in thyroid tumors--a comparison of real-time RT-PCR and IHC. The Journal of surgical research. vol 149. issue 1. 2008-09-16. PMID:18374945. |
increased extracellular matrix 1 (ecm1) expression, as determined by real-time reverse transcriptase-polymerase chain reaction (rt-pcr), has been recently proposed as a novel and independent diagnostic marker for malignant thyroid nodules. |
2008-09-16 |
2023-08-12 |
Not clear |
| Sandy Sercu, Mei Zhang, Noritaka Oyama, Uwe Hansen, Abdoel E L Ghalbzouri, Gu Jun, Kristof Geentjens, Lurong Zhang, Joseph H Merregaer. Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin. The Journal of investigative dermatology. vol 128. issue 6. 2008-06-24. PMID:18200062. |
interaction of extracellular matrix protein 1 with extracellular matrix components: ecm1 is a basement membrane protein of the skin. |
2008-06-24 |
2023-08-12 |
human |
| Sandy Sercu, Mei Zhang, Noritaka Oyama, Uwe Hansen, Abdoel E L Ghalbzouri, Gu Jun, Kristof Geentjens, Lurong Zhang, Joseph H Merregaer. Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin. The Journal of investigative dermatology. vol 128. issue 6. 2008-06-24. PMID:18200062. |
the extracellular matrix protein 1 (ecm1) is a secreted glycoprotein, which plays an important role in the structural and functional biology of the skin as demonstrated by the identification of loss-of-function mutations in ecm1 as cause of the genodermatosis lipoid proteinosis, characterized by reduplication of the skin basement membrane and hyalinization of the underlying dermis. |
2008-06-24 |
2023-08-12 |
human |
| Sandy Sercu, Mei Zhang, Noritaka Oyama, Uwe Hansen, Abdoel E L Ghalbzouri, Gu Jun, Kristof Geentjens, Lurong Zhang, Joseph H Merregaer. Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin. The Journal of investigative dermatology. vol 128. issue 6. 2008-06-24. PMID:18200062. |
to search for binding partner(s) of ecm1, we tested the in vitro binding activity of ecm1a, a major isoform of four ecm1 splice variants, to different skin extracellular matrix proteins (such as laminin 332, collagen type iv, and fibronectin) and polysaccharides (such as hyaluronan, heparin, and chondroitin sulfate a) with solid-phase binding assay. |
2008-06-24 |
2023-08-12 |
human |
| S Sercu, L Zhang, J Merregaer. The extracellular matrix protein 1: its molecular interaction and implication in tumor progression. Cancer investigation. vol 26. issue 4. 2008-06-02. PMID:18443958. |
the extracellular matrix protein 1 (ecm1) is expressed around blood vessels, which suggest a role for ecm1 in angiogenesis. |
2008-06-02 |
2023-08-12 |
chicken |
| S Sercu, Y Poumay, F Herphelin, J Liekens, L Beek, A Zwijsen, V Wessagowit, D Huylebroeck, J A McGrath, J Merregaer. Functional redundancy of extracellular matrix protein 1 in epidermal differentiation. The British journal of dermatology. vol 157. issue 4. 2008-03-06. PMID:17711528. |
extracellular matrix protein 1 (ecm1) is a secreted protein expressed in skin. |
2008-03-06 |
2023-08-12 |
Not clear |
| Ien Chan, Lu Liu, Takahiro Hamada, Gomathy Sethuraman, John A McGrat. The molecular basis of lipoid proteinosis: mutations in extracellular matrix protein 1. Experimental dermatology. vol 16. issue 11. 2008-01-07. PMID:17927570. |
in 2002, the disorder was mapped to a locus on chromosome 1q21 and pathogenic mutations were identified in the ecm1 gene, which encodes for the glycoprotein extracellular matrix protein 1 (ecm1). |
2008-01-07 |
2023-08-12 |
Not clear |
| Beibei Han, Xinglian Zhang, Qiang Liu, Xixue Chen, Xuejun Zh. Homozygous missense mutation in the ECM1 gene in Chinese siblings with lipoid proteinosis. Acta dermato-venereologica. vol 87. issue 5. 2007-12-14. PMID:17721643. |
lipoid proteinosis is caused by loss-of-function mutations in the glycoprotein extracellular matrix protein 1 (ecm1). |
2007-12-14 |
2023-08-12 |
Not clear |
| T Uchida, H Hayashi, M Inaoki, T Miyamoto, W Fujimot. A failure of mucocutaneous lymphangiogenesis may underlie the clinical features of lipoid proteinosis. The British journal of dermatology. vol 156. issue 1. 2007-05-17. PMID:17199583. |
lipoid proteinosis (lip) (omim 247100) is a rare autosomal recessive disease caused by loss of function mutations in the extracellular matrix protein 1 gene, ecm1, on chromosome 1q21. |
2007-05-17 |
2023-08-12 |
Not clear |
| Nicolae Mirancea, Ingrid Hausser, Dieter Metze, Hans-Jürgen Stark, Petra Boukamp, Dirk Breitkreut. Junctional basement membrane anomalies of skin and mucosa in lipoid proteinosis (hyalinosis cutis et mucosae). Journal of dermatological science. vol 45. issue 3. 2007-04-18. PMID:17175139. |
excessive basement membrane (bm) deposition in skin and mucosa is characteristic for lipoid proteinosis (lp; hyalinosis cutis et mucosae), an inherited disease caused by extracellular matrix protein 1 (ecm1) mutations. |
2007-04-18 |
2023-08-12 |
Not clear |
| Norihiro Fujimoto, Joseph Terlizzi, Sirpa Aho, Raymond Brittingham, Andrzej Fertala, Noritaka Oyama, John A McGrath, Jouni Uitt. Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions. Experimental dermatology. vol 15. issue 4. 2006-07-19. PMID:16512877. |
extracellular matrix protein 1 (ecm1), an approximately 85-kda glycoprotein with broad tissue distribution, harbors mutations in lipoid proteinosis (lp), a heritable disease characterized by reduplication of basement membranes and hyalinization of dermis, associated with neurologic disorders. |
2006-07-19 |
2023-08-12 |
human |
| Norihiro Fujimoto, Joseph Terlizzi, Sirpa Aho, Raymond Brittingham, Andrzej Fertala, Noritaka Oyama, John A McGrath, Jouni Uitt. Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions. Experimental dermatology. vol 15. issue 4. 2006-07-19. PMID:16512877. |
in this study, we explored ecm1 protein-protein interactions utilizing yeast two-hybrid genetic screen of human placental library, which identified nine interacting proteins, including matrix metalloproteinase 9 (mmp9). |
2006-07-19 |
2023-08-12 |
human |
| C S Sander, S Sercu, M Ziemer, U C Hipler, P Elsner, J J Thiele, J Merregaer. Expression of extracellular matrix protein 1 (ECM1) in human skin is decreased by age and increased upon ultraviolet exposure. The British journal of dermatology. vol 154. issue 2. 2006-06-08. PMID:16433788. |
expression of extracellular matrix protein 1 (ecm1) in human skin is decreased by age and increased upon ultraviolet exposure. |
2006-06-08 |
2023-08-12 |
human |
| C S Sander, S Sercu, M Ziemer, U C Hipler, P Elsner, J J Thiele, J Merregaer. Expression of extracellular matrix protein 1 (ECM1) in human skin is decreased by age and increased upon ultraviolet exposure. The British journal of dermatology. vol 154. issue 2. 2006-06-08. PMID:16433788. |
the extracellular matrix protein 1 (ecm1) is expressed in human skin and plays an important role in its normal structure and function. |
2006-06-08 |
2023-08-12 |
human |
| I Lupo, A B Cefalu, M R Bongiorno, O Daniele, V Valenti, D Noto, R Camarda, G Savettieri, M Aricò, M R Avern. A novel mutation of the extracellular matrix protein 1 gene (ECM1) in a patient with lipoid proteinosis (Urbach-Wiethe disease) from Sicily. The British journal of dermatology. vol 153. issue 5. 2006-02-03. PMID:16225617. |
a novel mutation of the extracellular matrix protein 1 gene (ecm1) in a patient with lipoid proteinosis (urbach-wiethe disease) from sicily. |
2006-02-03 |
2023-08-12 |
Not clear |
| I Lupo, A B Cefalu, M R Bongiorno, O Daniele, V Valenti, D Noto, R Camarda, G Savettieri, M Aricò, M R Avern. A novel mutation of the extracellular matrix protein 1 gene (ECM1) in a patient with lipoid proteinosis (Urbach-Wiethe disease) from Sicily. The British journal of dermatology. vol 153. issue 5. 2006-02-03. PMID:16225617. |
mutations within the extracellular matrix protein 1 (ecm1) gene cause lp. |
2006-02-03 |
2023-08-12 |
Not clear |
| S Desmet, S A Devos, I Chan, T Hamada, I Dhooge, J A McGrath, J M Naeyaer. Clinical and molecular abnormalities in lipoid proteinosis. European journal of dermatology : EJD. vol 15. issue 5. 2006-01-18. PMID:16172042. |
the diagnosis was confirmed by histology and identification of a homozygous frameshift mutation, 501insc, in exon 6 of the gene encoding extracellular matrix protein 1, ecm1. |
2006-01-18 |
2023-08-12 |
Not clear |
| Cezary Kowalewski, Anna Kozłowska, Ien Chan, Marta Górska, Katarzyna Woźniak, Stefania Jabłońska, John A McGrat. Three-dimensional imaging reveals major changes in skin microvasculature in lipoid proteinosis and lichen sclerosus. Journal of dermatological science. vol 38. issue 3. 2005-10-27. PMID:15927815. |
pathogenic mutations have been found in the extracellular matrix protein 1 gene (ecm1). |
2005-10-27 |
2023-08-12 |
Not clear |
| Norihiro Fujimoto, Joseph Terlizzi, Raymond Brittingham, Andrzej Fertala, John A McGrath, Jouni Uitt. Extracellular matrix protein 1 interacts with the domain III of fibulin-1C and 1D variants through its central tandem repeat 2. Biochemical and biophysical research communications. vol 333. issue 4. 2005-09-07. PMID:15990087. |
extracellular matrix protein 1 (ecm1), a widely expressed glycoprotein, has been shown to harbor mutations in lipoid proteinosis (lp), an autosomal recessive disorder characterized by profound alterations in the extracellular matrix of connective tissue. |
2005-09-07 |
2023-08-12 |
Not clear |
| Norihiro Fujimoto, Joseph Terlizzi, Raymond Brittingham, Andrzej Fertala, John A McGrath, Jouni Uitt. Extracellular matrix protein 1 interacts with the domain III of fibulin-1C and 1D variants through its central tandem repeat 2. Biochemical and biophysical research communications. vol 333. issue 4. 2005-09-07. PMID:15990087. |
since distinct splice variants of ecm1 and fibulin-1 have been shown to be co-expressed in tissues affected in lp, we propose that altered ecm1/fibulin-1 interactions may play a role in the pathogenesis of this disease as well as in a number of processes involving the extracellular matrix of connective tissues. |
2005-09-07 |
2023-08-12 |
Not clear |