Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J G Liu, R Li, G Q Li. l-S.R-daurisoline protects cultured hippocampal neurons against glutamate neurotoxicity by reducing nitric oxide production. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 20. issue 1. 1999-12-09. PMID:10437119. |
to explore mechanisms of l-s.r-daurisoline (ds)-mediated protection of cultured hippocampal neurons from sodium glutamate (glu) cytotoxicity. |
1999-12-09 |
2023-08-12 |
Not clear |
R J Jense. Responses of directionally selective retinal ganglion cells to activation of AMPA glutamate receptors. Visual neuroscience. vol 16. issue 2. 1999-07-02. PMID:10367956. |
previous studies in the rabbit retina have shown that drugs which block ampa glutamate receptors abolish directional selectivity in on-off directionally selective (ds) ganglion cells. |
1999-07-02 |
2023-08-12 |
rabbit |
A Oka, S Takashim. The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains. Acta neuropathologica. vol 97. issue 3. 1999-06-30. PMID:10090675. |
we investigated the expression of metabotropic glutamate receptor 5 (mglur5), a subtype of group i mglurs, in the cerebral cortex of cases with down's syndrome (ds), using immunohistochemistry and immunoblotting with this receptor. |
1999-06-30 |
2023-08-12 |
Not clear |
N M Grzywacz, D K Merwine, F R Amtho. Complementary roles of two excitatory pathways in retinal directional selectivity. Visual neuroscience. vol 15. issue 6. 1999-02-26. PMID:9839976. |
this supported the notion that glutamate provides the main excitatory drive to ds cells, that is, the one responsible for contrast sensitivity. |
1999-02-26 |
2023-08-12 |
rabbit |
C A Kittila, S C Masse. Pharmacology of directionally selective ganglion cells in the rabbit retina. Journal of neurophysiology. vol 77. issue 2. 1997-05-22. PMID:9065840. |
in this report we describe extracellular recordings made from on and on-off directionally selective (ds) ganglion cells in the rabbit retina during perfusion with agonists and antagonists to acetylcholine (ach), glutamate, and gamma-aminobutyric acid (gaba). |
1997-05-22 |
2023-08-12 |
rabbit |
F Lai, C X Chen, K C Carter, K Nishikur. Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases. Molecular and cellular biology. vol 17. issue 5. 1997-05-15. PMID:9111310. |
double-stranded (ds) rna-specific adenosine deaminase converts adenosine residues into inosines in dsrna and edits transcripts of certain cellular and viral genes such as glutamate receptor (glur) subunits and hepatitis delta antigen. |
1997-05-15 |
2023-08-12 |
human |
D Risser, G Lubec, N Cairns, M Herrera-Marschit. Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome. Life sciences. vol 60. issue 15. 1997-04-17. PMID:9096240. |
aspartate (asp), glutamate (glu), noradrenaline (na), dopamine (da) and its acidic metabolites dopac and hva, serotonin (5-ht) and its metabolite 5-hiaa were simultaneously investigated in post-mortem tissue samples from right parahippocampal gyrus (temporal cortex) and frontal cortical pole (frontal cortex) of adults with down syndrome (ds), and of neurologically healthy controls by use of high performance liquid chromatography (hplc). |
1997-04-17 |
2023-08-12 |
human |
A Manfridi, M Manci. Desynchronized (REM) sleep inhibition induced by carbachol microinjections into the nucleus basalis of Meynert is mediated by the glutamatergic system. Experimental brain research. vol 109. issue 1. 1996-11-27. PMID:8740223. |
pretreatment with these glutamate receptor antagonists counteracted the effect of carbachol on ds. |
1996-11-27 |
2023-08-12 |
rat |
A Manfridi, M Manci. Desynchronized (REM) sleep inhibition induced by carbachol microinjections into the nucleus basalis of Meynert is mediated by the glutamatergic system. Experimental brain research. vol 109. issue 1. 1996-11-27. PMID:8740223. |
moreover, our results tend to indicate that the decrease in ds following the injection of carbachol into the nbm is related to the release of endogenous glutamate. |
1996-11-27 |
2023-08-12 |
rat |
J H Brandstätter, U Greferath, T Euler, H Wässl. Co-stratification of GABAA receptors with the directionally selective circuitry of the rat retina. Visual neuroscience. vol 12. issue 2. 1995-07-25. PMID:7786855. |
bipolar cells, which could provide synaptic input to the ds circuitry, were stained with antibodies against the glutamate transporter glt-1. |
1995-07-25 |
2023-08-12 |
rat |
M Geoffroy, B Lambolez, E Audinat, B Hamon, F Crepel, J Rossier, R T Kad. Reduction of desensitization of a glutamate ionotropic receptor by antagonists. Molecular pharmacology. vol 39. issue 5. 1991-06-21. PMID:1709719. |
voltage-clamp current responses to qa, ampa, and glutamate (glu) exhibited a rapid increase followed by a decrease to a desensitized steady state (ds). |
1991-06-21 |
2023-08-11 |
rat |
b' N I Kalinina, G G Kurchavy\\xc4\\xa. [Properties of the response of frog motoneurons to glutamate application]. Neirofiziologiia = Neurophysiology. vol 20. issue 6. 1989-06-30. PMID:3249604.' |
the reversal potential (e) of the glutamate response produced by iontophoretically applied glutamate and that of the epsp's recorded from three synaptic inputs produced by reticular formation (rf), dorsal roots (ds), and microstimulation of presynaptic terminals (pt) at the point of glutamate application were compared at the same motoneuron of the isolated frog spinal cord using current-chop technique. |
1989-06-30 |
2023-08-11 |
Not clear |
M D Simpson, P Slater, A J Cross, D M Mann, M C Royston, J F Deakin, G P Reynold. Reduced D-[3H]aspartate binding in Down's syndrome brains. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2540884. |
the binding of d-[3h]aspartate to glutamate uptake sites was measured in post-mortem brains from subjects with down's syndrome (ds) and age-matched controls. |
1989-06-15 |
2023-08-11 |
human |
M D Simpson, P Slater, A J Cross, D M Mann, M C Royston, J F Deakin, G P Reynold. Reduced D-[3H]aspartate binding in Down's syndrome brains. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2540884. |
this study suggests that the reduction in glutamate uptake sites in ds is more substantial and widespread than in alzheimer's disease. |
1989-06-15 |
2023-08-11 |
human |