| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miyoung Yang, Joong-Sun Kim, Myoung-Sub Song, Jong-Choon Kim, Taekyun Shin, Seung-Sook Lee, Sung-Ho Kim, Changjong Moo. Dose-response and relative biological effectiveness of fast neutrons: induction of apoptosis and inhibition of neurogenesis in the hippocampus of adult mice. International journal of radiation biology. vol 86. issue 6. 2010-06-16. PMID:20470197. |
our study compared the effects of high linear energy transfer (let) fast neutrons on the induction of apoptosis and reduction of neurogenesis in the hippocampus of adult icr mice with those of low-let (60)co gamma-rays, to evaluate the relative biological effectiveness (rbe) of fast neutrons in the adult hippocampal dentate gyrus (dg). |
2010-06-16 |
2023-08-12 |
mouse |
| Takashi Kitamura, Yoshito Saitoh, Akiko Murayama, Hiroyuki Sugiyama, Kaoru Inokuch. LTP induction within a narrow critical period of immature stages enhances the survival of newly generated neurons in the adult rat dentate gyrus. Molecular brain. vol 3. 2010-06-15. PMID:20426820. |
previous study showed that high-frequency stimulation (hfs) of perforant path fibers to the hippocampal dentate gyrus (dg) induces the long-term potentiation (ltp) in the dg, and enhances the survival of newly generated neurons in the dg. |
2010-06-15 |
2023-08-12 |
rat |
| Matthew N Hill, Andrea K Titterness, Anna C Morrish, Erica J Carrier, Tiffany T-Y Lee, Joana Gil-Mohapel, Boris B Gorzalka, Cecilia J Hillard, Brian R Christi. Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. Hippocampus. vol 20. issue 4. 2010-06-14. PMID:19489006. |
voluntary exercise increased proliferation of progenitor cells, as evidenced by the increase in the number of ki-67 positive cells in the granule cell layer of the dentate gyrus (dg) in the hippocampus. |
2010-06-14 |
2023-08-12 |
Not clear |
| Patricia Mathieu, Ana Paula Piantanida, Fernando Pitoss. Chronic expression of transforming growth factor-beta enhances adult neurogenesis. Neuroimmunomodulation. vol 17. issue 3. 2010-06-14. PMID:20134202. |
neural stem cells reside in two neurogenic regions of the adult brain: the dentate gyrus of the hippocampus (dg) and the subventricular zone (svz). |
2010-06-14 |
2023-08-12 |
rat |
| Lintao Qu, Richard Boyce, L Stan Leun. Seizures in the developing brain result in a long-lasting decrease in GABA(B) inhibitory postsynaptic currents in the rat hippocampus. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20026210. |
additionally, hippocampal neurons of early-life seizure rats, as compared to those in control rats, showed a more depolarized resting membrane potential in both ca1 and dg, and a larger input resistance but reduced spike frequency adaptation in dg neurons. |
2010-06-08 |
2023-08-12 |
rat |
| Chenbo Zeng, Fenghui Pan, Lynne A Jones, Miranda M Lim, Elizabeth A Griffin, Yvette I Sheline, Mark A Mintun, David M Holtzman, Robert H Mac. Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain research. vol 1319. 2010-06-07. PMID:20064490. |
our data demonstrate that the number of edu-positive cells in the dentate gyrus of the hippocampus (dg) slightly increased in an edu dose-dependent manner in both the control and voluntary exercise (running) mouse groups. |
2010-06-07 |
2023-08-12 |
mouse |
| B D Eadie, W N Zhang, F Boehme, J Gil-Mohapel, L Kainer, J M Simpson, B R Christi. Fmr1 knockout mice show reduced anxiety and alterations in neurogenesis that are specific to the ventral dentate gyrus. Neurobiology of disease. vol 36. issue 2. 2010-06-03. PMID:19666116. |
the process of neurogenesis appears abnormal in young adult fmr1 ko mice, with significantly fewer bromodeoxyuridine-positive cells surviving for at least 4 weeks in the ventral subregion of the dentate gyrus (dg), a hippocampal subregion more closely associated with emotion than the dorsal dg. |
2010-06-03 |
2023-08-12 |
mouse |
| Giuliana Caronia, Jennifer Wilcoxon, Polina Feldman, Elizabeth A Grov. Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 18. 2010-06-02. PMID:20445055. |
given that no anatomical defects appeared in the double mutant telencephalon outside the dg, our observations support a growing literature that implicates the hippocampus in circuitry mediating fear and anxiety. |
2010-06-02 |
2023-08-12 |
mouse |
| Eric M Blalock, Richard Grondin, Kuey-chu Chen, Olivier Thibault, Veronique Thibault, Jignesh D Pandya, Amy Dowling, Zhiming Zhang, Patrick Sullivan, Nada M Porter, Philip W Landfiel. Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 17. 2010-05-24. PMID:20427664. |
in six young adult and six aging female rhesus monkeys, we analyzed gene expression in two major hippocampal subdivisions critical for memory/cognitive function [hippocampus proper, or cornu ammonis (ca), and dentate gyrus (dg)]. |
2010-05-24 |
2023-08-12 |
monkey |
| Avi Ring, Rita Tanso, Jens Noraber. The use of organotypic hippocampal slice cultures to evaluate protection by non-competitive NMDA receptor antagonists against excitotoxicity. Alternatives to laboratory animals : ATLA. vol 38. issue 1. 2010-05-18. PMID:20377305. |
quantitative densitometric image analysis of propidium iodide uptake in hippocampal regions ca1, ca3 and dg, showed that, after exposure to 10microm nmda for 24 hours, gk11 was the most potent of the three drugs, with an ic50 of about 50nm and complete protection at 250nm. |
2010-05-18 |
2023-08-12 |
Not clear |
| Feng Guo, Feng Sun, Jun-Ling Yu, Qing-Hua Wang, Da-Yu Tu, Xiao-Yuan Mao, Rui Liu, Kun-Can Wu, Ni Xie, Li-Ying Hao, Ji-Qun Ca. Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus. Brain research bulletin. vol 81. issue 4-5. 2010-05-06. PMID:19853022. |
in this study, the glutamate concentration in sers hippocampus was increased compared with that of control rats by high performance liquid chromatography; the mrna expressions of glast and mglur1 in sers hippocampus were significantly lower than those in control rats hippocampus, whereas an abundant increase in mrna for glt-1 was observed by rt-pcr; eaac-1 and mglur1 protein in sers and control rats were localized widely in the hippocampus including ca1, ca3 and dentate gyrus regions by immunohistochemistry; the number of glast and mglur1-positive cells in the hippocampus of sers were less than those in control rats, especially for ca3 and dg region; the protein expression of glt-1 was up-regulated, but the protein expressions of glast and mglur1 were down-regulated in ser hippocampus by western blot. |
2010-05-06 |
2023-08-12 |
rat |
| Sung Koo Kim, In Koo Hwang, Ki-Yeon Yoo, Dae Young Yoo, Eunjoo Bae, Choong Hyun Lee, Jung Hoon Choi, Ji Won Choi, Je Kyung Seong, Yeo Sung Yoon, Moo-Ho Wo. Pregnancy inhibits cell proliferation and neuroblast differentiation without neuronal damage in the hippocampal dentate gyrus in C57BL/6N mice. Brain research. vol 1315. 2010-05-06. PMID:20026318. |
in this study, we monitored neuronal damage, cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus (dg) at age-matched virgin control (17- to 18-week-old), gestation day (gd) 14.5, 16.5 and 18.5 (17- to 18-week-old dams), using neun for mature neurons, terminal deoxynucleotidyl dutp nick-end labeling (tunel) and fluoro-jade b (f-j b) for neuronal death, ki67 for cell proliferation and doublecortin (dcx) for neuroblast differentiation in c57bl/6 mice. |
2010-05-06 |
2023-08-12 |
mouse |
| Sung Koo Kim, In Koo Hwang, Ki-Yeon Yoo, Dae Young Yoo, Eunjoo Bae, Choong Hyun Lee, Jung Hoon Choi, Ji Won Choi, Je Kyung Seong, Yeo Sung Yoon, Moo-Ho Wo. Pregnancy inhibits cell proliferation and neuroblast differentiation without neuronal damage in the hippocampal dentate gyrus in C57BL/6N mice. Brain research. vol 1315. 2010-05-06. PMID:20026318. |
these results suggest that cell proliferation and neuroblast differentiation in dg of the hippocampus is decreased during gestation. |
2010-05-06 |
2023-08-12 |
mouse |
| Irina S Balan, Gary Fiskum, Tibor Kristia. Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique. Brain research. vol 1316. 2010-05-06. PMID:20036220. |
the ischemic insult resulted in a greater than 50% decline in the rate of formazan generation in the ca1 pyramidal neuronal layer of the hippocampus and in the parietal cortex and striatum, but not in the ca3 and dentate gyrus (dg) subregions of the hippocampus. |
2010-05-06 |
2023-08-12 |
rat |
| Arata Nakamura, Taro Kadowaki, Shin-ichi Sakakibara, Kanji Yoshimoto, Koichi Hirata, Shuichi Ued. Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection. Anatomical science international. vol 85. issue 1. 2010-05-03. PMID:19582544. |
after neonatal 5,7-dht injection, most serotonergic fibers in the hippocampus of 2-week-old mam rats had degenerated, while a small number of serotonergic fibers in the stratum lacunosum-moleculare (slm) of the hippocampus and in the hilus adjacent to the granular cell layer of the dentate gyrus (dg) had not. |
2010-05-03 |
2023-08-12 |
rat |
| Arata Nakamura, Taro Kadowaki, Shin-ichi Sakakibara, Kanji Yoshimoto, Koichi Hirata, Shuichi Ued. Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection. Anatomical science international. vol 85. issue 1. 2010-05-03. PMID:19582544. |
regenerating serotonergic fibers from the slm first extended terminals into the hippocampal heterotopia, then fibers from the hilus reinnervated the dg and some fibers extended to the heterotopia. |
2010-05-03 |
2023-08-12 |
rat |
| Nadège Sarrazin, Francesco Di Blasi, Valérie Roullot-Lacarrière, Françoise Rougé-Pont, Anne Le Roux, Pierre Costet, Jean-Michel Revest, Pier Vincenzo Piazz. Transcriptional effects of glucocorticoid receptors in the dentate gyrus increase anxiety-related behaviors. PloS one. vol 4. issue 11. 2010-04-26. PMID:19888328. |
we focused our study on a mouse line that expressed deltagr almost selectively in the glutamatergic neurons of the dentate gyrus (dg) of the hippocampus. |
2010-04-26 |
2023-08-12 |
mouse |
| Norifumi Shioda, Yui Yamamoto, Feng Han, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino, Kohji Fukunag. A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice. The Journal of pharmacology and experimental therapeutics. vol 333. issue 1. 2010-04-22. PMID:20068029. |
in the adult brain, neurogenesis persistently occurs in the subgranular zone of the hippocampal dentate gyrus (dg), and impaired neurogenesis is implicated in depressive behaviors and poor learning memory. |
2010-04-22 |
2023-08-12 |
mouse |
| Chandrasekharan L Indulekha, Rajendran Sanalkumar, Anoopkumar Thekkuveettil, Jackson Jame. Seizure induces activation of multiple subtypes of neural progenitors and growth factors in hippocampus with neuronal maturation confined to dentate gyrus. Biochemical and biophysical research communications. vol 393. issue 4. 2010-04-20. PMID:20171185. |
in our study, using pilocarpine-induced seizure model, we showed that seizure initiated activation of multiple progenitors in the entire hippocampal area such as dg, ca1 and ca3. |
2010-04-20 |
2023-08-12 |
Not clear |
| Chandrasekharan L Indulekha, Rajendran Sanalkumar, Anoopkumar Thekkuveettil, Jackson Jame. Seizure induces activation of multiple subtypes of neural progenitors and growth factors in hippocampus with neuronal maturation confined to dentate gyrus. Biochemical and biophysical research communications. vol 393. issue 4. 2010-04-20. PMID:20171185. |
type-3 (dcx(+ve)) progenitors showed increased expression of immature neurons only in dg region by 3 days after seizure induction indicating maturation of progenitors happens only in microenvironment of dg even though progenitors are activated in ca1 and ca3 regions of hippocampus. |
2010-04-20 |
2023-08-12 |
Not clear |