| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jariya Umka Welbat, Apiwat Sirichoat, Wunnee Chaijaroonkhanarak, Parichat Prachaney, Wanassanun Pannangrong, Poungrat Pakdeechote, Bungorn Sripanidkulchai, Peter Wigmor. Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival. Nutrients. vol 8. issue 5. 2017-02-28. PMID:27213437. |
these results indicate that vpa treatment caused impairments of spatial working memory, cell proliferation and survival in the subgranular zone (sgz) of the hippocampal dentate gyrus (dg). |
2017-02-28 |
2023-08-13 |
rat |
| Sueun Lee, Sohi Kang, Juhwan Kim, Seongwook Yoon, Sung-Ho Kim, Changjong Moo. Enhanced expression of immediate-early genes in mouse hippocampus after trimethyltin treatment. Acta histochemica. vol 118. issue 7. 2017-02-27. PMID:27614947. |
mice (7 weeks old, c57bl/6) administered tmt (2.6mg/kg intraperitoneally) presented severe neurodegenerative lesions in the dentate gyrus (dg) and showed behavioral seizure activity on days 1-4 post-treatment, after which the lesions and behavior recovered spontaneously over time. |
2017-02-27 |
2023-08-13 |
mouse |
| Anne Albrecht, Sebastian Ivens, Ismini E Papageorgiou, Gürsel Çalışkan, Nasrin Saiepour, Wolfgang Brück, Gal Richter-Levin, Uwe Heinemann, Oliver Stor. Shifts in excitatory/inhibitory balance by juvenile stress: A role for neuron-astrocyte interaction in the dentate gyrus. Glia. vol 64. issue 6. 2017-02-24. PMID:26875694. |
in the current study, we investigated the long-lasting impact of js on the expression of molecular factors for glutamate and γ-aminobutyric acid (gaba) uptake and turnover in sublayers of the dentate gyrus (dg) using laser microdissection and quantitative real-time polymerase chain reaction. |
2017-02-24 |
2023-08-13 |
rat |
| Sahreh Shabani, Alireza Sarkaki, Seyyed Ali Mard, Akram Ahangarpour, Layasadat Khorsandi, Yaghoob Farboo. Central and peripheral administrations of levothyroxine improved memory performance and amplified brain electrical activity in the rat model of Alzheimer's disease. Neuropeptides. vol 59. 2017-02-14. PMID:27640349. |
neuronal single unit recording was assessed from hippocampal dentate gyrus (dg). |
2017-02-14 |
2023-08-13 |
rat |
| Jianying Tian, Yougen Luo, Weiwei Chen, Shengsen Yang, Hao Wang, Jing Cui, Zhiyan Lu, Yuanye Lin, Yongyi B. MeHg Suppressed Neuronal Potency of Hippocampal NSCs Contributing to the Puberal Spatial Memory Deficits. Biological trace element research. vol 172. issue 2. 2017-02-03. PMID:26743863. |
mehg exposure induced defects in spatial learning and memory accompanied by a decrease in number of doublecortin (dcx)-positive cells in the dentate gyrus (dg). |
2017-02-03 |
2023-08-13 |
rat |
| Faramarz Faghihi, Ahmed A Moustaf. Impaired neurogenesis of the dentate gyrus is associated with pattern separation deficits: A computational study. Journal of integrative neuroscience. vol 15. issue 3. 2017-02-03. PMID:27650784. |
the separation of input patterns received from the entorhinal cortex (ec) by the dentate gyrus (dg) is a well-known critical step of information processing in the hippocampus. |
2017-02-03 |
2023-08-13 |
Not clear |
| Noura M S Osman, Ayman S Amer, Soha Abdelwaha. Effects of Ginko biloba leaf extract on the neurogenesis of the hippocampal dentate gyrus in the elderly mice. Anatomical science international. vol 91. issue 3. 2017-02-02. PMID:26297531. |
we used anti-caspase-3 as a marker of apoptosis, anti-gfap as a marker of neural stem cells, anti-ki-67 as a specific marker for cellular proliferation and anti-doublecortin (dcx) to detect newly born neurons in the hippocampal dentate gyrus (dg) of aged male mice. |
2017-02-02 |
2023-08-13 |
mouse |
| Hiroyoshi Inaba, Takuya Kishimoto, Satoru Oishi, Kan Nagata, Shunsuke Hasegawa, Tamae Watanabe, Satoshi Kid. Vitamin B1-deficient mice show impairment of hippocampus-dependent memory formation and loss of hippocampal neurons and dendritic spines: potential microendophenotypes of Wernicke-Korsakoff syndrome. Bioscience, biotechnology, and biochemistry. vol 80. issue 12. 2017-01-30. PMID:27576603. |
importantly, ptd mice exhibit a decrease in neurons in the ca1, ca3, and dentate gyrus (dg) regions of the hippocampus and reduced density of wide dendritic spines in the dg. |
2017-01-30 |
2023-08-13 |
mouse |
| Masanari Kanemitsu, Yukiko Fueta, Toru Ishidao, Shuji Aou, Hajime Hor. Development of a direct exposure system for studying the mechanisms of central neurotoxicity caused by volatile organic compounds. Industrial health. vol 54. issue 1. 2017-01-23. PMID:26320726. |
both 6.4 and 2.2 mm of 1-bp did not change the paired-pulse response, but fully suppressed long-term potentiation in the dentate gyrus (dg) of hippocampal slices obtained from rats, suggesting that 1-bp decreases synaptic plasticity in the dg at the concentrations tested. |
2017-01-23 |
2023-08-13 |
rat |
| Sui-Jun Guo, Yu Cui, Zhen-Zhen Huang, Huan Liu, Xue-Qin Zhang, Jin-Xiang Jiang, Wen-Jun Xi. Orexin A-mediated AKT signaling in the dentate gyrus contributes to the acquisition, expression and reinstatement of morphine-induced conditioned place preference. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25757577. |
accumulating evidence indicates that the hippocampal dentate gyrus (dg), a critical brain region contributing to learning and memory, is involved in the addiction and relapse to abused drugs. |
2017-01-10 |
2023-08-13 |
rat |
| Joel Zylberberg, Robert A Hyde, Ben W Strowbridg. Dynamics of robust pattern separability in the hippocampal dentate gyrus. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26482936. |
the dentate gyrus (dg) is thought to perform pattern separation on inputs received from the entorhinal cortex, such that the dg forms distinct representations of different input patterns. |
2017-01-06 |
2023-08-13 |
Not clear |
| K E Boschen, M J Ruggiero, A Y Klintsov. Neonatal binge alcohol exposure increases microglial activation in the developing rat hippocampus. Neuroscience. vol 324. 2017-01-03. PMID:26996510. |
on pd10, microglial cell counts and area of cell territory were assessed using unbiased stereology in the hippocampal subfields ca1, ca3 and dentate gyrus (dg), and hippocampal expression of pro- and anti-inflammatory genes was analyzed. |
2017-01-03 |
2023-08-13 |
rat |
| Luis E B Bettio, Vivian B Neis, Francis L Pazini, Patricia S Brocardo, Anna R Patten, Joana Gil-Mohapel, Brian R Christie, Ana Lúcia S Rodrigue. The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation. The European journal of neuroscience. vol 43. issue 8. 2016-12-30. PMID:26779605. |
quantitative microscopic analysis did not reveal significant alterations in the numbers of ki-67- and proliferating cell nuclear antigen (pcna)-positive cells in the hippocampal dentate gyrus (dg) of guanosine-treated mice. |
2016-12-30 |
2023-08-13 |
mouse |
| Mohsen Nategh, Sara Nikseresht, Fariba Khodagholi, Fereshteh Motamed. Inactivation of nucleus incertus impairs passive avoidance learning and long term potentiation of the population spike in the perforant path-dentate gyrus evoked field potentials in rats. Neurobiology of learning and memory. vol 130. 2016-12-30. PMID:26927304. |
in the present study we aimed to address if ni is involved in an avoidance learning task as well as dentate gyrus (dg) short-term and long-term potentiation. |
2016-12-30 |
2023-08-13 |
rat |
| Jeong-Hwi Cho, Joon Ha Park, Ji Hyeon Ahn, Jae-Chul Lee, In Koo Hwang, Seung Min Park, Ji Yun Ahn, Dong Won Kim, Jun Hwi Cho, Jong-Dai Kim, Young-Myeong Kim, Moo-Ho Won, Il-Jun Kan. Vanillin and 4-hydroxybenzyl alcohol promotes cell proliferation and neuroblast differentiation in the dentate gyrus of mice via the increase of brain-derived neurotrophic factor and tropomyosin-related kinase B. Molecular medicine reports. vol 13. issue 4. 2016-12-30. PMID:26935641. |
in the present study, the effects of vanillin and 4‑hba were first investigated on cell proliferation, as well as neuronal differentiation and integration of granule cells in the dentate gyrus (dg) of adolescent mice using ki‑67, doublecortin (dcx) immunohistochemistry and 5‑bromo‑2'‑deoxyuridine (brdu)/feminizing locus on x 3 (neun) double immunofluorescence. |
2016-12-30 |
2023-08-13 |
mouse |
| Xinwei Li, Deyu Li, Qiongling Li, Yuxia Li, Kuncheng Li, Shuyu Li, Ying Ha. Hippocampal subfield volumetry in patients with subcortical vascular mild cognitive impairment. Scientific reports. vol 6. 2016-12-19. PMID:26876151. |
we utilized an automated hippocampal subfield segmentation method provided by freesurfer to estimate the volume of several hippocampal subfields, including the cornu ammonis (ca) areas, the dentate gyrus (dg), the subiculum and the presubiculum. |
2016-12-19 |
2023-08-13 |
Not clear |
| Jun-Cheng Weng, Maria A Tikhonova, Jian-Horng Chen, Mei-Shiuan Shen, Wan-Yun Meng, Yen-Ting Chang, Ke-Hsin Chen, Keng-Chen Liang, Ching-Sui Hung, Tamara G Amstislavskaya, Ying-Jui H. Ceftriaxone prevents the neurodegeneration and decreased neurogenesis seen in a Parkinson's disease rat model: An immunohistochemical and MRI study. Behavioural brain research. vol 305. 2016-12-16. PMID:26940602. |
the results showed that mptp lesioning resulted in decreased neuronal activity and density in the nigrostriatal dopaminergic (daergic) system and the hippocampal ca1, ca3, and dentate gyrus (dg) areas and reduced neurogenesis in the dg, but in hyperactivity in the subthalamic nucleus (stn). |
2016-12-16 |
2023-08-13 |
rat |
| Sung S Choi, Sang-Rae Lee, Hong J Le. Neurorestorative Role of Stem Cells in Alzheimer's Disease: Astrocyte Involvement. Current Alzheimer research. vol 13. issue 4. 2016-12-15. PMID:27018261. |
neurogenesis is maintained in both neonatal and adult brain, although it is dramatically reduced in aged neurogenic brain region such as the subgranular layer and subventricular zone of the dentate gyrus (dg). |
2016-12-15 |
2023-08-13 |
Not clear |
| F L'Episcopo, J Drouin-Ouellet, C Tirolo, A Pulvirenti, R Giugno, N Testa, S Caniglia, M F Serapide, G Cisbani, R A Barker, F Cicchetti, B Marchett. GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions. Cell death & disease. vol 7. 2016-12-15. PMID:27124580. |
we identified a disease and stage-dependent upregulation of gsk-3β mrna and protein levels in the hd hippocampus, with the active isoform pgsk-3β-tyr(216) being strongly expressed in dentate gyrus (dg) neurons and astrocytes at a time when phosphorylation of tau at the at8 epitope was also present in these same neurons. |
2016-12-15 |
2023-08-13 |
mouse |
| Helen E Scharfman, Catherine E Myer. Corruption of the dentate gyrus by "dominant" granule cells: Implications for dentate gyrus function in health and disease. Neurobiology of learning and memory. vol 129. 2016-12-13. PMID:26391451. |
the dentate gyrus (dg) and area ca3 of the hippocampus are highly organized lamellar structures which have been implicated in specific cognitive functions such as pattern separation and pattern completion. |
2016-12-13 |
2023-08-13 |
Not clear |