Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Soraya Martín-Suárez, Oihane Abiega, Ana Ricobaraza, Rubén Hernandez-Alcoceba, Juan Manuel Encina. Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32793597. |
hippocampal neurogenesis, the process by which neural stem cells (nscs) continuously generate new neurons in the dentate gyrus (dg) of most mammals including humans, is chiefly regulated by neuronal activity. |
2020-09-28 |
2023-08-13 |
mouse |
Patrícia Patrício, António Mateus-Pinheiro, Nuno Dinis Alves, Mónica Morais, Ana João Rodrigues, João Miguel Bessa, Nuno Sousa, Luísa Pint. miR-409 and miR-411 Modulation in the Adult Brain of a Rat Model of Depression and After Fluoxetine Treatment. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32848656. |
previous microarray analysis from our group has disclosed molecular players in the hippocampal dentate gyrus (dg), in the context of depression and antidepressant treatment. |
2020-09-28 |
2023-08-13 |
rat |
Hao Wang, Glen M Abel, Daniel R Storm, Zhengui Xi. Cadmium Exposure Impairs Adult Hippocampal Neurogenesis. Toxicological sciences : an official journal of the Society of Toxicology. 2020-09-28. PMID:31271426. |
adult hippocampal neurogenesis is a process in which adult neural progenitor/stem cells (anpcs) in the subgranular zone (sgz) of the dentate gyrus (dg) generate functional new neurons in the hippocampus which contributes to hippocampus-dependent learning and memory. |
2020-09-28 |
2023-08-13 |
mouse |
Ryan D Webler, Sasha Fulton, Tarique D Perera, Jeremy D Copla. Maturational phase of hippocampal neurogenesis and cognitive flexibility. Neuroscience letters. vol 711. 2020-09-28. PMID:31430544. |
dentate gyrus (dg) neurogenesis may facilitate pattern separation by blocking memory retrieval via inhibition of non-neurogenic downstream ca3 neurons. |
2020-09-28 |
2023-08-13 |
Not clear |
Mary Youssef, Piray Atsak, Jovani Cardenas, Stylianos Kosmidis, E David Leonardo, Alex Dranovsk. Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30858462. |
the long-term behavioral consequences of early life stress may therefore be due in part to interference with hippocampal development, in particular with assembly of the dentate gyrus (dg) region of the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
Golo Kronenberg, Karen Gertz, Ria Uhlemann, Melanie T C Kuffner, Imke Kirste, Junfeng An, Nafisa M Jadavji, Bjoern H Schott, Thomas Scheffel, Matthias Endres, Rainer Hellweg, Christoph Harm. Reduced Hippocampal Neurogenesis in Mice Deficient in Apoptosis Repressor with Caspase Recruitment Domain (ARC). Neuroscience. vol 416. 2020-09-24. PMID:31356897. |
in the adult hippocampal dentate gyrus (dg), the majority of newly generated cells are eliminated by apoptotic mechanisms. |
2020-09-24 |
2023-08-13 |
mouse |
Darya Frank, Marcelo A Montemurro, Daniela Montald. Pattern Separation Underpins Expectation-Modulated Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 17. 2020-09-23. PMID:32161140. |
all subfields showed more dissimilar representations for unexpected items, with dentate gyrus (dg) and ca3 being more sensitive to expectation violation than ca1. |
2020-09-23 |
2023-08-13 |
human |
Shauna M Stark, C Brock Kirwan, Craig E L Star. Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity. Trends in cognitive sciences. vol 23. issue 11. 2020-09-22. PMID:31597601. |
the hippocampus is critical for learning and memory, relying in part on pattern separation processes supported by the dentate gyrus (dg) to prevent interference from overlapping memory representations. |
2020-09-22 |
2023-08-13 |
Not clear |
Mahsa Pourhamzeh, Roghaye Mozafari, Shole Jamali, Fereshteh Motamedi, Reza Ahadi, Abbas Haghparas. Involvement of orexin receptors within the hippocampal dentate gyrus in morphine-induced reinstatement in food-deprived rats. Behavioural brain research. vol 375. 2020-09-22. PMID:31422071. |
the orexinergic terminals innervate neurons of the hippocampal dentate gyrus (dg) which is a key structure in the maintenance and reinstatement of drug addiction. |
2020-09-22 |
2023-08-13 |
rat |
Shoji Nishida, Ryota Araki, Akihiro Baba, Sota Asari, Shin Tachibana, Yuki Nakajima, Arimi Iwakumo, Takeshi Yab. Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice. Journal of pharmacological sciences. vol 143. issue 2. 2020-09-15. PMID:32173264. |
in the dentate gyrus (dg) of the hippocampus, decreased number of newborn mature neurons and increased number of immature neurons were observed in low folate diet-fed mice. |
2020-09-15 |
2023-08-13 |
mouse |
Zahra Shabani, Javad Mahmoudi, Fereshteh Farajdokht, Saeed Sadigh-Etegha. An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis. Archives of medical research. vol 51. issue 4. 2020-09-15. PMID:32279909. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz), which is in the dentate gyrus (dg) of the hippocampus, are the central regions of neurogenesis in the brain. |
2020-09-15 |
2023-08-13 |
Not clear |
Janasha Goffigan-Holmes, Dafne Sanabria, Johana Diaz, Debra Flock, Raul Chavez-Valde. Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory. Developmental neuroscience. 2020-09-12. PMID:30861522. |
in both anterior and posterior coronal brain sections, hippocampal calb1 expression doubled between p11 and p40 due to an increase in the cornus ammonis (ca) field (kruskal-wallis [kw] p < 0.001) and not the dentate gyrus (dg). |
2020-09-12 |
2023-08-13 |
mouse |
Sara Elfarrash, Nanna Møller Jensen, Nelson Ferreira, Cristine Betzer, Jervis Vermal Thevathasan, Robin Diekmann, Mohamed Adel, Nisreen Mansour Omar, Mohamed Z Boraie, Sabry Gad, Jonas Ries, Deniz Kirik, Sadegh Nabavi, Poul Henning Jense. Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta neuropathologica communications. vol 7. issue 1. 2020-09-11. PMID:31856920. |
pff injection at dentate gyrus (dg) templates the formation of endogenous α-synuclein aggregates in axons and cell bodies of this region that spread to ca3 and ca1 regions. |
2020-09-11 |
2023-08-13 |
mouse |
Pascal J D Goetghebeur, Keith A Wesnes, Steven D Targu. D-Cycloserine Improves Difficult Discriminations in a Pattern Separation Task in Alzheimer's Disease Patients with Dementia. Journal of Alzheimer's disease : JAD. vol 69. issue 2. 2020-09-10. PMID:30958353. |
recent fmri studies in human identified that pattern separation ability is associated with increased activity in the hippocampal dentate gyrus (dg), whereas no such dg changes are seen during pattern completion. |
2020-09-10 |
2023-08-13 |
human |
Runrui Zhang, Marcelo Boareto, Anna Engler, Angeliki Louvi, Claudio Giachino, Dagmar Iber, Verdon Taylo. Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus. Cell reports. vol 28. issue 6. 2020-09-09. PMID:31390563. |
neural stem cells (nscs) in the adult mouse hippocampal dentate gyrus (dg) are mostly quiescent, and only a few are in cell cycle at any point in time. |
2020-09-09 |
2023-08-13 |
mouse |
Tao Wang, Melissa T Maltez, Heow Won Lee, Monir Ahmad, Hong-Wei Wang, Frans H H Leene. Effect of exercise training on the FNDC5/BDNF pathway in spontaneously hypertensive rats. Physiological reports. vol 7. issue 24. 2020-09-08. PMID:31883222. |
bdnf mrna was lower in the dentate gyrus (dg) of shr, which was normalized by exercise. |
2020-09-08 |
2023-08-13 |
rat |
Kyung-Ran Kim, Seung Yeon Lee, Sang Ho Yoon, Yoonsub Kim, Hyeon-Ju Jeong, Sanghyeon Lee, Young Ho Suh, Jong-Sun Kang, Hana Cho, Suk-Ho Lee, Myoung-Hwan Kim, Won-Kyung H. Kv4.1, a Key Ion Channel For Low Frequency Firing of Dentate Granule Cells, Is Crucial for Pattern Separation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 11. 2020-09-08. PMID:32047055. |
the dentate gyrus (dg) in the hippocampus may play key roles in remembering distinct episodes through pattern separation, which may be subserved by the sparse firing properties of granule cells (gcs) in the dg. |
2020-09-08 |
2023-08-13 |
mouse |
Jiuyang Ding, Shanshan Hu, Yunle Meng, Chen Li, Jian Huang, Yitong He, Pingming Qi. Alpha-Synuclein deficiency ameliorates chronic methamphetamine induced neurodegeneration in mice. Toxicology. vol 438. 2020-08-31. PMID:32278788. |
meth increased α-syn level in the stratum oriens, pyramidal layer, stratum radiatum and stratum moleculare of hippocampal ca1, ca2 and ca3, polymorph layer of hippocampal dentate gyrus (dg), and substantia nigra (sn). |
2020-08-31 |
2023-08-13 |
mouse |
Tao Xu, Xinyuan Yu, Jing Deng, Shu Ou, Xi Liu, Teng Wang, Ying Liu, Juan Yang, Changhong Tan, Jinxian Yuan, Yangmei Che. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell death & disease. vol 10. issue 11. 2020-08-26. PMID:31672961. |
here, we found that cxcr7 was upregulated in the hippocampal dentate gyrus (dg) of mice subjected to kainic acid (ka)-induced epilepsy and in the brain tissues of patients with temporal lobe epilepsy. |
2020-08-26 |
2023-08-13 |
mouse |
Alexandra T Keinath, Andrés Nieto-Posadas, Jennifer C Robinson, Mark P Brando. DG-CA3 circuitry mediates hippocampal representations of latent information. Nature communications. vol 11. issue 1. 2020-08-26. PMID:32541860. |
we then hypothesize that the representation of latent information in ca1 is mediated by pattern separation/completion processes instantiated upstream within the dentate gyrus (dg) and ca3 subregions. |
2020-08-26 |
2023-08-13 |
Not clear |