| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyung-Ran Kim, Yoonsub Kim, Hyeon-Ju Jeong, Jong-Sun Kang, Sang Hun Lee, Yujin Kim, Suk-Ho Lee, Won-Kyung H. Impaired pattern separation in Tg2576 mice is associated with hyperexcitable dentate gyrus caused by Kv4.1 downregulation. Molecular brain. vol 14. issue 1. 2021-04-09. PMID:33785038. |
based on previous studies suggesting a critical role of dentate gyrus (dg) in pattern separation, we investigated functional changes in dg of tg2576 mice. |
2021-04-09 |
2023-08-13 |
mouse |
| Dongseok Park, Seungjoon Kim, Hyeonho Kim, Jungsu Shin, Hyeji Jung, Ji Won U. Seizure progression triggered by IQSEC3 loss is mitigated by reducing activated microglia in mice. Glia. vol 68. issue 12. 2021-04-06. PMID:32645240. |
in the current study, we show that mice with hippocampal dentate gyrus (dg)-specific iqsec3 knockdown (kd) exhibit microglial activation and death of dg granule cell. |
2021-04-06 |
2023-08-13 |
mouse |
| Rebecca M Ruddy, Daniel Derkach, Parvati Dadwal, Cindi M Morshea. Cranial irradiation in juvenile mice leads to early and sustained defects in the stem and progenitor cell pools and late cognitive impairments. Brain research. vol 1727. 2021-04-05. PMID:31715143. |
several rodent models have demonstrated that these cognitive deficits may be correlated with damage to neural progenitor cells in the subventricular zone (svz) and dentate gyrus (dg), the two neurogenic niches of the brain. |
2021-04-05 |
2023-08-13 |
mouse |
| Ning-Ning Cai, Zheng-Zhu Wang, Xian-Chun Zhu, Yu Jiang, Wen-Qian Zhu, Rui Yang, Xue-Ming Zhan. Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus. Journal of chemical neuroanatomy. vol 105. 2021-04-02. PMID:32027950. |
since the neurogenesis in the hippocampal dentate gyrus (dg) is more important to learning, memory and cognition, here we further examined their effects on the adult dg neurogenesis. |
2021-04-02 |
2023-08-13 |
mouse |
| José Carlos Delgado-González, Carlos de la Rosa-Prieto, Diana Lucía Tarruella-Hernández, Nuria Vallejo-Calcerrada, Sandra Cebada-Sánchez, Ricardo Insausti, Emilio Artacho-Pérul. Neuronal volume of the hippocampal regions in ageing. Journal of anatomy. vol 237. issue 2. 2021-04-01. PMID:32314379. |
this study analysed the neuronal islands of layer ii of the entorhinal cortex (ec), the neuronal clumps of the external principal layer of the presubiculum (prs) and the dentate granule cells of the dentate gyrus (dg), which represent the prominent structural regions within the hf circuit. |
2021-04-01 |
2023-08-13 |
human |
| Branden R Nelson, Rebecca D Hodge, Ray Am Daza, Prem Prakash Tripathi, Sebastian J Arnold, Kathleen J Millen, Robert F Hevne. Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches. eLife. vol 9. 2021-03-30. PMID:32238264. |
the hippocampal dentate gyrus (dg) is a unique brain region maintaining neural stem cells (ncss) and neurogenesis into adulthood. |
2021-03-30 |
2023-08-13 |
mouse |
| Ghazaleh Omidi, Seyed Asaad Karimi, Siamak Shahidi, Nafiseh Faraji, Alireza Komak. Coenzyme Q10 supplementation reverses diabetes-related impairments in long-term potentiation induction in hippocampal dentate gyrus granular cells: An in vivo study. Brain research. vol 1726. 2021-03-29. PMID:31560865. |
the population spike (ps) amplitude and slope of excitatory post synaptic potentials (epsps) were measured in dentate gyrus (dg) area in response to the stimulation applied to the perforant path (pp). |
2021-03-29 |
2023-08-13 |
rat |
| Aline Siteneski, Gislaine Olescowicz, Francis L Pazini, Anderson Camargo, Daiane B Fraga, Patricia S Brocardo, Joana Gil-Mohapel, Mauricio P Cunha, Ana Lúcia S Rodrigue. Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 3. 2021-03-26. PMID:31974720. |
immunohistochemical analyses to evaluate hippocampal cell proliferation, neuronal survival, and neuronal commitment and maturation, as well as expression of fndc5 c-terminal fragment were performed in the entire, dorsal, and ventral dentate gyrus (dg) of the hippocampus. |
2021-03-26 |
2023-08-13 |
mouse |
| Heekyung Lee, Zitong Wang, Scott L Zeger, Michela Gallagher, James J Knieri. Heterogeneity of Age-Related Neural Hyperactivity along the CA3 Transverse Axis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 4. 2021-03-26. PMID:33257325. |
we suggest that, in combination with altered inputs from the entorhinal cortex and dentate gyrus (dg), the proximal ca3 region of aged rats may switch from its normal function that reflects the pattern separation output of the dg and instead performs a computation that reflects an abnormal bias toward pattern completion. |
2021-03-26 |
2023-08-13 |
rat |
| Xiaomin Zhang, Peter Jona. Integration of spatial and non-spatial information by heterogeneous dentate gyrus granule cells. Journal of life sciences (Westlake Village, Calif.). vol 2. issue 4. 2021-03-26. PMID:33409506. |
it is divided into three main subregions: the dentate gyrus (dg), the ca3 area, and the ca1 region, which are linearly interconnected to form a so-called trisynaptic circuit. |
2021-03-26 |
2023-08-13 |
Not clear |
| A González-Maciel, R M Romero-Velázquez, A Alfaro-Rodríguez, P Sanchez Aparicio, R Reynoso-Roble. Prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. Journal of chemical neuroanatomy. vol 103. 2021-03-23. PMID:31794794. |
apoptosis was detected at three postnatal ages using the tunel technique in the ca1, and ca3 regions of the hippocampus and in the dentate gyrus (dg); neurogenesis was assessed in the dg using an antibody against doublecortin. |
2021-03-23 |
2023-08-13 |
rat |
| Christina Strauch, Denise Manahan-Vaugha. Orchestration of Hippocampal Information Encoding by the Piriform Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 1. 2021-03-22. PMID:31220213. |
in behaving rats, test-pulse stimulation of the anterior piriform cortex (apc) evoked field potentials in the dentate gyrus (dg). |
2021-03-22 |
2023-08-13 |
rat |
| Irene Puig-Parnau, Soleil Garcia-Brito, Nastaran Faghihi, Carme Gubern, Laura Aldavert-Vera, Pilar Segura-Torres, Gemma Huguet, Elisabet Kádá. Intracranial Self-Stimulation Modulates Levels of SIRT1 Protein and Neural Plasticity-Related microRNAs. Molecular neurobiology. vol 57. issue 6. 2021-03-19. PMID:32219698. |
we used openarray to select mirna candidates differentially expressed in the dentate gyrus (dg) of icss-treated (3 sessions, 45' session/day) and sham rats. |
2021-03-19 |
2023-08-13 |
rat |
| Zane R Lybrand, Sonal Goswami, Jingfei Zhu, Veronica Jarzabek, Nikolas Merlock, Mahafuza Aktar, Courtney Smith, Ling Zhang, Parul Varma, Kyung-Ok Cho, Shaoyu Ge, Jenny Hsie. A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy. Nature communications. vol 12. issue 1. 2021-03-18. PMID:33658509. |
in the mammalian hippocampus, adult-born granule cells (abgcs) contribute to the function of the dentate gyrus (dg). |
2021-03-18 |
2023-08-13 |
mouse |
| Jasper O Nuninga, René C W Mandl, Marco P Boks, Steven Bakker, Metten Somers, Sophie M Heringa, Wendy Nieuwdorp, Hans Hoogduin, René S Kahn, Peter Luijten, Iris E C Somme. Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:30867562. |
in the animal analog of ect, neurogenesis in the dentate gyrus (dg) of the hippocampus is observed. |
2021-03-17 |
2023-08-13 |
human |
| Mathias Lundberg, Sophie Curbo, Hannes Bohman, Ingrid Agartz, Sven-Ove Ögren, Cesare Patrone, Shiva Mansour. Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy. Bioscience reports. vol 40. issue 1. 2021-03-16. PMID:31919522. |
the antipsychotic drug clozapine was shown to counteract the observed decrease in brdu-labelled cells in hippocampal dentate gyrus (dg). |
2021-03-16 |
2023-08-13 |
mouse |
| Amir Segev, Masaya Yanagi, Daniel Scott, Sarah A Southcott, Jacob M Lister, Chunfeng Tan, Wei Li, Shari G Birnbaum, Saïd Kourrich, Carol A Tamming. Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:30038231. |
in this study, we used a subfield-specific glun1 knockout mouse with a disease-like molecular perturbation expressed only in hippocampal dentate gyrus (dg) and assessed its association with hippocampal physiology and psychosis-like behaviors. |
2021-03-15 |
2023-08-13 |
mouse |
| Jasmin Weninger, Maurice Meseke, Shaleen Rana, Eckart Förste. Heat-Shock Induces Granule Cell Dispersion and Microgliosis in Hippocampal Slice Cultures. Frontiers in cell and developmental biology. vol 9. 2021-03-12. PMID:33693000. |
granule cell dispersion (gcd) has been found in the dentate gyrus (dg) of patients with temporal lobe epilepsy (tle) and a history of febrile seizures but was also recently observed in pediatric patients that did not suffer from epilepsy. |
2021-03-12 |
2023-08-13 |
Not clear |
| Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Ch. Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. Journal of neurochemistry. vol 155. issue 4. 2021-03-10. PMID:32314365. |
a 9.4-tesla mr imaging system was used to study dti indices, namely fractional anisotropy (fa), mean diffusivity (md), and intervoxel coherence (ic) in the hippocampal ca1 and dentate gyrus (dg) areas. |
2021-03-10 |
2023-08-13 |
Not clear |
| Scott D Sawchuk, Hannah M O Reid, Katie J Neale, James Shin, Brian R Christi. Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus. Brain plasticity (Amsterdam, Netherlands). vol 6. issue 1. 2021-03-10. PMID:33680851. |
we examined how acute ethanol (etoh) exposure affects long term depression (ltd) in the dentate gyrus (dg) of the hippocampus in juvenile rats. |
2021-03-10 |
2023-08-13 |
rat |