| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deep R Sharma, Bokun Cheng, Manoj Kumar Jaiswal, Xusheng Zhang, Ajeet Kumar, Nirzar Parikh, Divya Singh, Hardik Sheth, Merina Varghese, Kostantin Dobrenis, Xiaolei Zhang, Patrick R Hof, Patric K Stanton, Praveen Ballab. Elevated insulin growth factor-1 in dentate gyrus induces cognitive deficits in pre-term newborns. Cerebral cortex (New York, N.Y. : 1991). 2023-01-16. PMID:36646459. |
here, we show that prematurity and associated neonatal stress disrupt dentate gyrus (dg) development and induce long-term cognitive deficits and that these effects are mediated by insulin growth factor-1 (igf1). |
2023-01-16 |
2023-08-14 |
Not clear |
| Yoon Ji Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yan. Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices. STAR protocols. vol 4. issue 1. 2023-01-12. PMID:36633949. |
longitudinal synaptic connections between dentate gyrus (dg) granule neurons in the hippocampus have been found to be correlated with increased anxiety. |
2023-01-12 |
2023-08-14 |
mouse |
| Masoumeh Nazari, Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Kourosh Arami, Alireza Komak. Underlying mechanisms of long-term potentiation during the inhibition of the cannabinoid CB1 and GABAB receptors in the dentate gyrus of hippocampus. BMC neuroscience. vol 24. issue 1. 2023-01-12. PMID:36635629. |
in our previous work, we showed that cb1 antagonists increased the population spike (ps) amplitude, field excitatory post-synaptic potential (fepsp), and the ltp induction in the dentate gyrus (dg) of the rat hippocampus while the gaba |
2023-01-12 |
2023-08-14 |
mouse |
| Yuanduo Liu, Hongying Ma, Yangyang Wang, Boxu Ren, Lian Liu, Anbang Sun, Fengru Tan. Neonatal exposure to low-dose X-ray causes behavioral defects and abnormal hippocampal development in mice. IUBMB life. 2023-01-11. PMID:36629313. |
neuroinflammatory cells were observed in the dentate gyrus (dg) and ca3 areas of the hippocampus at pd3 + 1. |
2023-01-11 |
2023-08-14 |
mouse |
| Nien-Chu Shih, Nyoman D Kurniawan, Ryan P Cabeen, Laura Korobkova, Ellen Wong, Helena C Chui, Kristi A Clark, Carol A Miller, Debra Hawes, Kymry T Jones, Farshid Sepehrban. Microstructural mapping of dentate gyrus pathology in Alzheimer's disease: A 16.4 Tesla MRI study. NeuroImage. Clinical. vol 37. 2023-01-11. PMID:36630864. |
the dentate gyrus (dg) is an integral portion of the hippocampal formation, and it is composed of three layers. |
2023-01-11 |
2023-08-14 |
human |
| Lívia Neves, Bruno Lobão-Soares, Ana Paula de Castro Araujo, Alan Michel Bezerra Furtunato, Izabela Paiva, Nicholy Souza, Anne Kelly Morais, George Nascimento, Elaine Gavioli, Adriano Bretanha Lopes Tort, Flávio Freitas Barbosa, Hindiael Belchio. Theta and gamma oscillations in the rat hippocampus support the discrimination of object displacement in a recognition memory task. Frontiers in behavioral neuroscience. vol 16. 2023-01-09. PMID:36620858. |
studies on hippocampal lesions in rodents have shown that dentate gyrus (dg) and ca3 are necessary to detect object displacement in memory tasks. |
2023-01-09 |
2023-08-14 |
rat |
| Matthew A De Niear, Garrett R Smith, Mercedes Robinson, Malcolm Moses-Hampton, Puneet G Lakhmani, Nicholas A Upright, Emma L Krause, Julio J Ramire. Lesion-induced sprouting promotes neurophysiological integration of septal and entorhinal inputs to granule cells in the dentate gyrus of rats. Neurobiology of learning and memory. 2023-01-09. PMID:36621561. |
axonal sprouting of dentate gyrus (dg) afferents after entorhinal cortex (ec) lesion is a model preparation to assess lesion-induced functional reorganization in a denervated target structure. |
2023-01-09 |
2023-08-14 |
rat |
| Satoshi Deyama, Shun Aoki, Rinako Sugie, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. Intranasal Administration of Resolvin E1 Produces Antidepressant-Like Effects via BDNF/VEGF-mTORC1 Signaling in the Medial Prefrontal Cortex. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023-01-09. PMID:36622634. |
additionally, local infusion of rve1 into the medial prefrontal cortex (mpfc) or dorsal hippocampal dentate gyrus (dg) produces antidepressant-like effects. |
2023-01-09 |
2023-08-14 |
mouse |
| Jacqueline A Bonds, Elif Tunc-Ozcan, Sara R Dunlop, Radhika Rawat, Chian-Yu Peng, John A Kessle. Why Some Mice Are Smarter Than Others: The Impact of Bone Morphogenetic Protein Signaling on Cognition. eNeuro. 2023-01-03. PMID:36596594. |
examination of micro-dissected dentate gyrus (dg) after cognitive testing showed a highly significant negative correlation between levels of bone morphometric protein (bmp) signaling and recognition memory. |
2023-01-03 |
2023-08-14 |
mouse |
| Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications. vol 11. issue 1. 2023-01-03. PMID:36597124. |
the dentate gyrus (dg), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the alzheimer's type due to alzheimer's disease (dat-ad), but less is known about the susceptibility of the dg to other tauopathies. |
2023-01-03 |
2023-08-14 |
human |
| Shirley Jaqueline Szriber, Leonardo Santana Novaes, Nilton Barreto Dos Santos, Carolina Demarchi Munhoz, Deise Carla Almeida Leite-Dellov. Imbalance in the ratio between mineralocorticoid and glucocorticoid receptors and neurodegeneration in the dentate gyrus of aged dogs. Veterinary world. vol 15. issue 11. 2023-01-02. PMID:36590120. |
given the aging changes in dogs' dentate gyrus (dg) and the possible involvement of cortisol receptors in this process, this study aimed to evaluate the expression of mr and gr and neuronal degeneration in this hippocampal region of aged dogs. |
2023-01-02 |
2023-08-14 |
Not clear |
| Azahara Oliva, Antonio Fernandez-Ruiz, Lindsay A Karab. CA2 orchestrates hippocampal network dynamics. Hippocampus. 2022-12-28. PMID:36575880. |
the hippocampus is composed of various subregions: ca1, ca2, ca3, and the dentate gyrus (dg). |
2022-12-28 |
2023-08-14 |
Not clear |
| Eu-Gene Kim, Wonseok Chang, SangYep Shin, Anjana Silwal Adhikari, Geun Hee Seol, Dae-Yong Song, Sun Seek Mi. Maternal separation in mice leads to anxiety-like/aggressive behavior and increases immunoreactivity for glutamic acid decarboxylase and parvalbumin in the adolescence ventral hippocampus. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 27. issue 1. 2022-12-28. PMID:36575939. |
gad67-positive neurons were increased in the hippocampal regions we observed: dentate gyrus (dg), ca3, ca1, subiculum, presubiculum, and parasubiculum. |
2022-12-28 |
2023-08-14 |
mouse |
| Youri G Bolsius, Pim R A Heckman, Camilla Paraciani, Sophia Wilhelm, Frank Raven, Elroy L Meijer, Martien J H Kas, Steve Ramirez, Peter Meerlo, Robbert Haveke. Recovering object-location memories after sleep deprivation-induced amnesia. Current biology : CB. 2022-12-28. PMID:36577400. |
here, we show that hippocampal object-location memories formed under sleep deprivation conditions can be successfully retrieved multiple days following training, using optogenetic dentate gyrus (dg) memory engram activation or treatment with the clinically approved phosphodiesterase 4 (pde4) inhibitor roflumilast. |
2022-12-28 |
2023-08-14 |
mouse |
| Alyssa M Ash, Elena Regele-Blasco, Désirée R Seib, Erin Chahley, Patrick D Skelton, Bryan W Luikart, Jason S Snyde. Adult-born Neurons Inhibit Developmentally-born Neurons during Spatial Learning. Neurobiology of learning and memory. 2022-12-26. PMID:36572174. |
ongoing neurogenesis in the dentate gyrus (dg) subregion of the hippocampus results in a heterogenous population of neurons. |
2022-12-26 |
2023-08-14 |
rat |
| Anita Lewczuk, Barbara Zablocka, Malgorzata Beresewicz-Halle. Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region? Molecular neurobiology. 2022-12-22. PMID:36547847. |
an example of endogenous neuroprotection is ischemia-resistance of the hippocampal regions comprising the ca2, ca3, ca4 and dentate gyrus subfields (here abbreviated to ca2-4,dg) which can be contrasted with the ischemia-vulnerable ca1 region. |
2022-12-22 |
2023-08-14 |
Not clear |
| Jessy D Martinez, William P Brancaleone, Kathryn G Peterson, Lydia G Wilson, Sara J Ato. Atypical hypnotic compound ML297 restores sleep architecture immediately following emotionally-valenced learning, to promote memory consolidation and hippocampal network activation during recall. Sleep. 2022-12-13. PMID:36510822. |
we find that improvements in cfm consolidation due to ml297 are sleep-dependent, and are associated with increased numbers of highly-activated dentate gyrus (dg), ca1, and ca3 neurons during cfm recall. |
2022-12-13 |
2023-08-14 |
mouse |
| Kıymet Kübra Tüfekci, Elfide Gizem Bakirhan, Funda Terz. A Maternal High-Fat Diet Causes Anxiety-Related Behaviors by Altering Neuropeptide Y1 Receptor and Hippocampal Volumes in Rat Offspring: the Potential Effect of N-Acetylcysteine. Molecular neurobiology. 2022-12-11. PMID:36502431. |
stereological data indicated significant decreases in the total volume of the hippocampus and ca1 and dentate gyrus (dg) regions in the obese (ob) group (p < 0.01). |
2022-12-11 |
2023-08-14 |
rat |
| Meng-Ying Liu, Lu-Lu Wei, Xian-Hui Zhu, Hua-Chen Ding, Xiang-Hu Liu, Huan Li, Yuan-Yuan Li, Zhou Han, Lian-Di Li, Zi-Wei Du, Ya-Ping Zhou, Jing Zhang, Fan Meng, Yu-Lin Tang, Xiao Liu, Chun Wang, Qi-Gang Zho. Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor. Molecular psychiatry. 2022-12-09. PMID:36481932. |
we found that the level of tert in the dentate gyrus (dg) of the hippocampus during the developmental stage determines the responses of the hpa axis to stressful events in adulthood through modulating the excitability of the dentate granular cells (dgcs) rather than the expression of gr. |
2022-12-09 |
2023-08-14 |
mouse |
| Anirudh R Acharya, Lars Emil Larsen, Jean Delbeke, Wytse J Wadman, Kristl Vonck, Alfred Meurs, Paul Boon, Robrecht Raed. In vivo inhibition of epileptiform afterdischarges in rat hippocampus by light-activated chloride channel, stGtACR2. CNS neuroscience & therapeutics. 2022-12-09. PMID:36482869. |
the present study investigated whether activation of stgtacr2 in granule cells of the dentate gyrus (dg) inhibits epileptic afterdischarges in a rat model. |
2022-12-09 |
2023-08-14 |
rat |