| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Gu, J R Forsayeth, S Verrall, X M Yu, Z W Hal. Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells. The Journal of cell biology. vol 114. issue 4. 1991-09-17. PMID:1869588. |
high expression of delta or gamma subunits also each inhibited formation of a heterodimer with alpha and the other subunit. |
1991-09-17 |
2023-08-11 |
mouse |
| Y Gu, J R Forsayeth, S Verrall, X M Yu, Z W Hal. Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells. The Journal of cell biology. vol 114. issue 4. 1991-09-17. PMID:1869588. |
these results are consistent with a defined pathway for achr assembly in which alpha delta and alpha gamma heterodimers are formed first, followed by association with the beta subunit and with each other to form the complete achr. |
1991-09-17 |
2023-08-11 |
mouse |
| S D Thompson, A R Manzo, J Pelkonen, M Larche, J L Hurwit. Developmental T cell receptor gene rearrangements: relatedness of the alpha/beta and gamma/delta T cell precursor. European journal of immunology. vol 21. issue 8. 1991-09-13. PMID:1831133. |
as evidence that gamma/delta and alpha/beta gene rearrangements appeared concomitantly in individual precursors, it was found that: (a) multiple adult thymocytes bore alpha gene rearrangements on one chromosome and delta gene rearrangements on the homologous chromosome, and (b) v gamma 3-j gamma 1 rearrangements, prominent joins in the early gamma/delta t cell population, were also prominent in the early alpha/beta t cell subset. |
1991-09-13 |
2023-08-11 |
Not clear |
| Y Tasaki, R Takamori, Y Koshihar. Prostaglandin D2 metabolite stimulates collagen synthesis by human osteoblasts during calcification. Prostaglandins. vol 41. issue 4. 1991-09-13. PMID:1871375. |
northern blot analysis showed that 10(-5) m delta 12-pgj2 and 10(-8) m 1,25(oh)2d3 enhanced the transcription of type i procollagen (alpha 1) mrna levels in osteoblasts. |
1991-09-13 |
2023-08-11 |
human |
| A E Lacerda, H S Kim, P Ruth, E Perez-Reyes, V Flockerzi, F Hofmann, L Birnbaumer, A M Brow. Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature. vol 352. issue 6335. 1991-09-12. PMID:1650913. |
complementary dnas encoding the five subunits of the dihydropyridine receptor, alpha 1, beta, gamma, alpha 2 and delta, have been cloned and it is now recognized that alpha 2 and delta are derived from a common precursor. |
1991-09-12 |
2023-08-11 |
mouse |
| A E Lacerda, H S Kim, P Ruth, E Perez-Reyes, V Flockerzi, F Hofmann, L Birnbaumer, A M Brow. Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature. vol 352. issue 6335. 1991-09-12. PMID:1650913. |
the alpha 1 subunit can itself produce ca2+ currents, as was demonstrated using mouse l cells lacking alpha 2 delta, beta and gamma (our unpublished results). |
1991-09-12 |
2023-08-11 |
mouse |
| B Zhang, S Watanabe, K Akiyama, T Li, K Fukushima, K Tsutsui, S Sek. Peplomycin-induced DNA repair synthesis in permeable mouse ascites sarcoma cells. Acta medica Okayama. vol 45. issue 2. 1991-09-11. PMID:1714230. |
analyses using selective inhibitors for dna polymerases showed that both dna polymerase beta and aphidicolin-sensitive dna polymerases (dna polymerase alpha and/or delta) were involved in the repair dna synthesis. |
1991-09-11 |
2023-08-11 |
mouse |
| J A Bluestone, R Q Cron, T A Barrett, B Houlden, A I Sperling, A Dent, S Hedrick, B Rellahan, L A Mati. Repertoire development and ligand specificity of murine TCR gamma delta cells. Immunological reviews. vol 120. 1991-09-09. PMID:1650760. |
in addition, at least 6 different v delta gene products (v delta 2,4,5,6,v alpha 10, v alpha 11) are expressed in peripheral lymphoid tissue. |
1991-09-09 |
2023-08-11 |
mouse |
| J A Bluestone, R Q Cron, T A Barrett, B Houlden, A I Sperling, A Dent, S Hedrick, B Rellahan, L A Mati. Repertoire development and ligand specificity of murine TCR gamma delta cells. Immunological reviews. vol 120. 1991-09-09. PMID:1650760. |
although the tg+ tcr gamma delta cells are tolerized by thymic clonal tolerance similar to tcr alpha beta cells, the epithelial tg+ tcr gamma delta cells are subjected to non-deletional tolerance (anergy). |
1991-09-09 |
2023-08-11 |
mouse |
| A Carbone, R Harbeck, A Dallas, D Nemazee, T Finkel, R O'Brien, R Kubo, W Bor. Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies. Immunological reviews. vol 120. 1991-09-09. PMID:1830862. |
alpha beta t-lymphocyte depleted mice, a model for gamma delta t-lymphocyte functional studies. |
1991-09-09 |
2023-08-11 |
mouse |
| A Carbone, R Harbeck, A Dallas, D Nemazee, T Finkel, R O'Brien, R Kubo, W Bor. Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies. Immunological reviews. vol 120. 1991-09-09. PMID:1830862. |
suppression of alpha beta t-cell development results in the loss of alloantigen reactivity and of b-cell help, suggesting that gamma delta and alpha beta populations differ in their functional capabilities. |
1991-09-09 |
2023-08-11 |
mouse |
| A Carbone, R Harbeck, A Dallas, D Nemazee, T Finkel, R O'Brien, R Kubo, W Bor. Alpha beta T-lymphocyte depleted mice, a model for gamma delta T-lymphocyte functional studies. Immunological reviews. vol 120. 1991-09-09. PMID:1830862. |
alpha beta-suppressed mice and rats may provide model systems for studies on gamma delta cell function in vivo. |
1991-09-09 |
2023-08-11 |
mouse |
| K Selmaj, C F Brosnan, C S Rain. Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 15. 1991-09-04. PMID:1830662. |
twenty-eight of 43 ms lesions contained tcr gamma delta cells and these were most frequently found in chronically demyelinated areas, in contrast to the previously studied cd4+, cd8+ (tcr alpha beta) population, which predominated in more active lesions. |
1991-09-04 |
2023-08-11 |
Not clear |
| M E Roth, P O Holman, D M Kran. Nonrandom use of J alpha gene segments. Influence of V alpha and J alpha gene location. Journal of immunology (Baltimore, Md. : 1950). vol 147. issue 3. 1991-08-30. PMID:1907305. |
the repertoire of alpha beta and gamma delta cells is shaped first by genetic processes that control rearrangement and expression and then by intercellular processes that "select" cells expressing only particular receptors. |
1991-08-30 |
2023-08-11 |
Not clear |
| Y Obata, O Taguchi, Y Matsudaira, H Hasegawa, N Hamasima, T Takahash. Abnormal thymic development, impaired immune function and gamma delta T cell lymphomas in a TL transgenic mouse strain. The Journal of experimental medicine. vol 174. issue 2. 1991-08-28. PMID:1713249. |
these events are associated with the abolishment of t cell receptor (tcr) alpha beta lineage of the t cell differentiation, leading to preponderance of cells belonging to the tcr gamma delta l3t4-lyt-2- double negative (dn) lineage. |
1991-08-28 |
2023-08-11 |
mouse |
| C L Yang, S J Zhang, N L Toomey, T N Palmer, M Y Le. Induction of DNA polymerase activities in the regenerating rat liver. Biochemistry. vol 30. issue 30. 1991-08-27. PMID:1677271. |
the levels of dna polymerase alpha and delta activities in regenerating liver extracts were determined by the use of the dna polymerase alpha specific inhibitor, buadatp [2-(p-n-butylanilino)-9-(2-deoxy-beta-d-ribofuranosyl) adenine 5'-triphosphate], and monoclonal antibodies. |
1991-08-27 |
2023-08-11 |
rat |
| S M Sine, T Claudi. Stable expression of the mouse nicotinic acetylcholine receptor in mouse fibroblasts. Comparison of receptors in native and transfected cells. The Journal of biological chemistry. vol 266. issue 21. 1991-08-23. PMID:1713208. |
the biochemical, pharmacological, and single channel measurements indicate at least 95% of the surface achrs on am4 cells are alpha 2 beta gamma delta pentamers. |
1991-08-23 |
2023-08-11 |
mouse |
| H S Lillehoj, L D Baco. Increase of intestinal intraepithelial lymphocytes expressing CD8 antigen following challenge infection with Eimeria acervulina. Avian diseases. vol 35. issue 2. 1991-08-22. PMID:1830202. |
eimerian infection-induced changes in the intestinal intraepithelial lymphocyte (iel) subpopulations expressing cd8 antigen (cytotoxic/suppressor t cells) or antigen-specific t cell receptor (tcr) heterodimer alpha beta (tcr2) or gamma delta (tcr1) were investigated in f2 crosses of 15i5 b-congenic chickens differing for the major histocompatibility complex (mhc). |
1991-08-22 |
2023-08-11 |
Not clear |
| R Scolla. T-cell subset relationships in thymocyte development. Current opinion in immunology. vol 3. issue 2. 1991-08-20. PMID:1676890. |
however, the exact nature of the events that lead uncommitted cells to choose a particular lineage (either alpha beta/gamma delta or cd4+/cd8+) has still not been determined. |
1991-08-20 |
2023-08-11 |
Not clear |
| A Winot. Regulation of the early stages of T-cell development. Current opinion in immunology. vol 3. issue 2. 1991-08-20. PMID:1829896. |
studies at the transcriptional level of t-cell receptor gene regulation have started to yield important clues about how different t-cell-specific genes can share the same transcription factors and how alpha beta and gamma delta t cells are differentially regulated. |
1991-08-20 |
2023-08-11 |
mouse |