| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Sheehy, C A Emler, T W Mak, J P Pande. Human genes for the immunoglobulin gamma-chain (Gm) allotypes and for the T cell receptor alpha-chain are distantly linked or unlinked. Experimental and clinical immunogenetics. vol 8. issue 1. 1991-11-06. PMID:1832881. |
since the genes for two of the t cell receptor (tcr) chains (alpha and delta) and for the immunoglobulin (ig) heavy chains (alpha, gamma, delta, epsilon and mu) are all on the long arm of human chromosome 14, it is of interest to determine if they are genetically linked and, if so, how strongly. |
1991-11-06 |
2023-08-11 |
human |
| S J Frank, L E Samelson, R D Klausne. The structure and signalling functions of the invariant T cell receptor components. Seminars in immunology. vol 2. issue 2. 1991-11-04. PMID:2151801. |
in addition to the clone-specific alpha beta or gamma delta heterodimer antigen recognition element, each tcr has five invariant chains--the cd3-gamma, -delta, and -epsilon chains and a zeta zeta or zeta eta disulfide dimer. |
1991-11-04 |
2023-08-11 |
Not clear |
| J A Punt, R T Kubo, T Saito, T H Finkel, S Kathiresan, K J Blank, Y Hashimot. Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins. The Journal of experimental medicine. vol 174. issue 4. 1991-11-01. PMID:1717631. |
we described, however, a cd4+/cd8+ transformed murine thymocyte, kkf, that expresses surface tcr-beta chains in the absence of gamma, delta, and alpha proteins; these beta chains are only weakly associated with cd3-epsilon and cd3-zeta. |
1991-11-01 |
2023-08-11 |
Not clear |
| M P Lefran. Organization of the human T-cell receptor genes. European cytokine network. vol 1. issue 3. 1991-11-01. PMID:2129796. |
whereas the conventional t-cell receptors are heterodimers of alpha and beta chains, expressed at the surface of cd3+ cd4+ and cd3+ cd8+ t lymphocytes, the gamma delta t-cell receptors are found at the surface of a subset of t-lymphocytes of phenotype cd3+ cd4- cd8-. |
1991-11-01 |
2023-08-11 |
human |
| M P Lefran. Organization of the human T-cell receptor genes. European cytokine network. vol 1. issue 3. 1991-11-01. PMID:2129796. |
the synthesis of the t-cell receptor chains results from the junction (or rearrangement) of dna segments: variable (v) gene and joining (j) segment for the alpha and gamma chains, v gene, d (diversity) and j segments for the beta and delta chains. |
1991-11-01 |
2023-08-11 |
human |
| J P Allison, W L Havra. The immunobiology of T cells with invariant gamma delta antigen receptors. Annual review of immunology. vol 9. 1991-10-31. PMID:1832874. |
the restricted localization and expression of invariant antigen receptors may equip the epithelial gamma delta t cells to perform specialized functions which differ from those of circulating alpha beta and gamma delta tcr+ cells. |
1991-10-31 |
2023-08-11 |
Not clear |
| A Convit, P Czobor, J Volavk. Lateralized abnormality in the EEG of persistently violent psychiatric inpatients. Biological psychiatry. vol 30. issue 4. 1991-10-31. PMID:1912127. |
the number of instances of violence as well as the number of staff interventions were related to increased delta band activity and to decreased alpha band activity in the temporal and the parietooccipital areas. |
1991-10-31 |
2023-08-11 |
Not clear |
| W Scheule. EEG sleep activities react topographically different to GABAergic sleep modulation by flunitrazepam: relationship to regional distribution of benzodiazepine receptor subtypes? Neuropsychobiology. vol 23. issue 4. 1991-10-31. PMID:1966625. |
an increase in power density was found in the frontal regions for the alpha 2 and sigma 1 frequency band whereas a decrease in power density was emphasized in the posterior regions for the delta and alpha 1 frequency band. |
1991-10-31 |
2023-08-11 |
Not clear |
| G Milligan, F M Mitchell, I Mullaney, S J McClue, F R McKenzi. The role and specificity of guanine nucleotide binding proteins in receptor-effector coupling. Symposia of the Society for Experimental Biology. vol 44. 1991-10-31. PMID:1966633. |
with this approach we have been able to demonstrate that a delta opioid receptor-mediated inhibition of adenylate cyclase in neuroblastoma x glioma, ng108-15, cell membranes is transduced specifically by gi2 and in the same cell that alpha 2 adrenergic inhibition of ca2+ currents is transduced by go. |
1991-10-31 |
2023-08-11 |
Not clear |
| J C Jones, T Stevnsner, M R Mattern, V A Boh. Effect of specific enzyme inhibitors on replication, total genome DNA repair and on gene-specific DNA repair after UV irradiation in CHO cells. Mutation research. vol 255. issue 2. 1991-10-30. PMID:1656249. |
we tested inhibitors of dna polymerase alpha and delta (aphidicolin), of poly(adpr) polymerase (3-aminobenzamide), of ribonucleotide reductase (hydroxyurea), of topoisomerase i (camptothecin), and of topoisomerase ii (merbarone, vp-16). |
1991-10-30 |
2023-08-11 |
Not clear |
| D Gagliardi, F Penin, D C Gauthero. Large-scale purification and characterization of the five subunits of F1-ATPase from pig heart mitochondria. Biochimica et biophysica acta. vol 1059. issue 3. 1991-10-29. PMID:1832960. |
removal of endogenous nucleotides from that enzyme before dissociation led to the efficient separation of the alpha and gamma subunits from beta, delta and epsilon subunits. |
1991-10-29 |
2023-08-11 |
rat |
| K Imoto, T Konno, J Nakai, F Wang, M Mishina, S Num. A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor. FEBS letters. vol 289. issue 2. 1991-10-28. PMID:1717313. |
from the results obtained, we conclude that a ring of uncharged polar residues comprising threonine 244 of the alpha-subunit (alpha t244), beta s250, gamma t253 and delta s258 (referred to as the central ring) and the anionic intermediate ring, which are adjacent to each other in the assumed alpha-helical configuration of the m2-containing transmembrane segment, together form a narrow channel constriction of short length, located close to the cytoplasmic side of the membrane. |
1991-10-28 |
2023-08-11 |
xenopus_laevis |
| W Born, R Harbeck, R L O'Brie. Possible links between immune system and stress response: the role of gamma delta T lymphocytes. Seminars in immunology. vol 3. issue 1. 1991-10-24. PMID:1680012. |
the response of gamma delta cells to hsp 60 differs from that of alpha beta t cells and b cells in several ways: the frequency of reactive gamma delta clones is high. |
1991-10-24 |
2023-08-11 |
Not clear |
| D Singer, M Biel, I Lotan, V Flockerzi, F Hofmann, N Dasca. The roles of the subunits in the function of the calcium channel. Science (New York, N.Y.). vol 253. issue 5027. 1991-10-24. PMID:1716787. |
the channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha 2, delta, beta, and gamma (alpha 2 and delta are encoded by a single messenger rna). |
1991-10-24 |
2023-08-11 |
xenopus_laevis |
| D Singer, M Biel, I Lotan, V Flockerzi, F Hofmann, N Dasca. The roles of the subunits in the function of the calcium channel. Science (New York, N.Y.). vol 253. issue 5027. 1991-10-24. PMID:1716787. |
the alpha 2, delta, and gamma subunits also have pronounced effects on its macroscopic characteristics, such as kinetics, voltage dependence of activation and inactivation, and enhancement by a dihydropyridine agonist. |
1991-10-24 |
2023-08-11 |
xenopus_laevis |
| V N Kakkanaiah, M Nagarkatti, J A Bluestone, P S Nagarkatt. CD4-CD8- thymocytes from MRL-lpr/lpr mice exhibit abnormal proportions of alpha beta- and gamma delta-TCR+ cells and demonstrate defective responsiveness when activated through the TCR. Cellular immunology. vol 137. issue 2. 1991-10-22. PMID:1832583. |
the dn thymocytes from young lpr or mrl-(+/+) mice demonstrated strong and similar proliferative responsiveness to stimulation with pma + calcium ionophore or pma + il-2, or to immobilized mab directed against the tcrs (cd3, alpha beta and gamma delta). |
1991-10-22 |
2023-08-11 |
mouse |
| C Grégoire, N Rebaï, F Schweisguth, A Necker, G Mazza, N Auphan, A Millward, A M Schmitt-Verhulst, B Malisse. Engineered secreted T-cell receptor alpha beta heterodimers. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 18. 1991-10-21. PMID:1716770. |
two of these antibodies were found to react specifically with the products of the v alpha 2 (v delta 8) and v beta 2 gene segments, respectively. |
1991-10-21 |
2023-08-11 |
mouse |
| D M Psatta, R Goldstein, M Mate. EEG mapping in mentally retarded children by synthetic arginine vasotocin administration. Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie. vol 29. issue 1-2. 1991-10-21. PMID:1892783. |
it resulted from a significant reduction in the percent amount of theta and delta activity and from the increase in alpha activity. |
1991-10-21 |
2023-08-11 |
Not clear |
| T W Groghan, J L Davignon, J Evans, J P Allison, R A Eisenberg, J A Frelinger, P L Cohe. Diminished expression of the T cell receptor on the expanded lymphocyte population in MRL/Mp-lpr/lpr mice. Autoimmunity. vol 2. issue 2. 1991-10-21. PMID:2562377. |
dna and rna were prepared from mrl/mp-lpr/lpr (lpr) and congenic mrl/mp(-)+/+ (+/+) mice by standard techniques and studied by southern blot, northern blot, and dot blot analysis using the cdnas tt11, specific for the tcr alpha chain; 86t5, specific for the tcr beta chain; and t3 delta; specific for the subunit of the t3 molecule. |
1991-10-21 |
2023-08-11 |
mouse |
| N Dahmen, L Kowalzick, S Spadari, G Koc. Arabinose furanosyl thymidine: uptake, phosphorylation and incorporation into DNA of mammalian cells. In vivo (Athens, Greece). vol 4. issue 1. 1991-10-17. PMID:1966522. |
incorporation into dna was studied under different conditions, including selective inhibition of the different cellular dna polymerases by aphidicolin (that inhibits polymerases alpha and delta) and dideoxythymidine (that preferentially inhibits polymerases beta and gamma). |
1991-10-17 |
2023-08-11 |
Not clear |