| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Ohanian, J Ohanian, L Shaw, S Scarth, P J Parker, A M Heagert. Identification of protein kinase C isoforms in rat mesenteric small arteries and their possible role in agonist-induced contraction. Circulation research. vol 78. issue 5. 1996-06-18. PMID:8620600. |
phorbol esters, which activate pkc and cause smooth muscle contraction, downregulated only the alpha and delta isoforms. |
1996-06-18 |
2023-08-12 |
rat |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
calnexin associates exclusively with individual cd3 delta and t cell antigen receptor (tcr) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit tcr complexes. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
most t lymphocytes express on their surfaces an oligomeric protein complex consisting of clonotypic alpha beta polypeptides associated with invariant cd3-gamma delta epsilon and zeta chains, designated the t cell antigen receptor (tcr) complex. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
here, we studied the role of glucose (glc) trimming and calnexin association in the oligomerization of tcr alpha and cd3 delta glycoproteins in murine splenic t lymphocytes, a model cell type for efficient assembly of complete tcr complexes. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
we show that removal of glc residues from both cd3 delta proteins and tcr alpha proteins occurred prior to their association with any other tcr components and that calnexin specifically interacted with unassembled tcr alpha and cd3 delta proteins containing incompletely trimmed oligosaccharides. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
interestingly, we found that removal of glc residues from glycan chains was necessary for efficient association of calnexin with tcr alpha glycoproteins but not with cd3 delta glycoproteins. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
these studies define glc trimming and calnexin association as initial molecular events in the translation of cd3 delta and tcr alpha proteins occurring coincident with or immediately after their translocation into the endoplasmic reticulum and preceding the ordered pairing of tcr chains. |
1996-06-18 |
2023-08-12 |
Not clear |
| J E van Leeuwen, K P Kears. Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor (TCR) alpha proteins containing incompletely trimmed glycans that are not assembled into multisubunit TCR complexes. The Journal of biological chemistry. vol 271. issue 16. 1996-06-18. PMID:8621641. |
in addition, these data document that calnexin assembly with cd3 delta and tcr alpha glycoproteins involves both glycan-dependent and glycan-independent mechanisms. |
1996-06-18 |
2023-08-12 |
Not clear |
| K Fujihashi, S Kawabata, T Hiroi, M Yamamoto, J R McGhee, S Nishikawa, H Kiyon. Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 8. 1996-06-18. PMID:8622984. |
the sources of these two cytokines for gamma delta t cells were neighboring epithelial cells (il-7) and alpha beta t cells (il-2 and il-7). |
1996-06-18 |
2023-08-12 |
Not clear |
| K Fujihashi, S Kawabata, T Hiroi, M Yamamoto, J R McGhee, S Nishikawa, H Kiyon. Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 8. 1996-06-18. PMID:8622984. |
cytokine signaling by il-2 and il-7 from alpha beta t cells and epithelial cells was necessary for the expression of il-7r and il-2r, respectively, on a subset of gamma delta t cells (e.g., gamma delta (dim) t cells) in mucosa-associated tissue for subsequent activation and cell division. |
1996-06-18 |
2023-08-12 |
Not clear |
| F Jouen-Beades, D Gilbert, S Ramzaoui, F Borsa-Lebas, G Humbert, F Tro. Similarity of expression of activation markers and CD28 on gamma delta and alpha beta-receptor T cells in HIV infection. Clinical immunology and immunopathology. vol 79. issue 2. 1996-06-17. PMID:8620625. |
similarity of expression of activation markers and cd28 on gamma delta and alpha beta-receptor t cells in hiv infection. |
1996-06-17 |
2023-08-12 |
human |
| F Jouen-Beades, D Gilbert, S Ramzaoui, F Borsa-Lebas, G Humbert, F Tro. Similarity of expression of activation markers and CD28 on gamma delta and alpha beta-receptor T cells in HIV infection. Clinical immunology and immunopathology. vol 79. issue 2. 1996-06-17. PMID:8620625. |
moreover, an increased expression of cd38 and/or hla-dr molecules was found on gamma delta t cells as reported for alpha beta t cells indicating that all categories of circulating t lymphocytes share similar phenotypic abnormalities in hiv-infected patients. |
1996-06-17 |
2023-08-12 |
human |
| S Tsuji, D Char, R P Bucy, M Simonsen, C H Chen, M D Coope. Gamma delta T cells are secondary participants in acute graft-versus-host reactions initiated by CD4+ alpha beta T cells. European journal of immunology. vol 26. issue 2. 1996-06-13. PMID:8617313. |
gamma delta t cells are secondary participants in acute graft-versus-host reactions initiated by cd4+ alpha beta t cells. |
1996-06-13 |
2023-08-12 |
human |
| S Tsuji, D Char, R P Bucy, M Simonsen, C H Chen, M D Coope. Gamma delta T cells are secondary participants in acute graft-versus-host reactions initiated by CD4+ alpha beta T cells. European journal of immunology. vol 26. issue 2. 1996-06-13. PMID:8617313. |
to examine the role of t cell subpopulations in an acute graft-versus-host (gvh) reaction, gamma delta t cells and alpha beta t cells expressing one of the two prototypic v beta families were negatively isolated from adult blood samples and injected into allogeneic chick embryos. |
1996-06-13 |
2023-08-12 |
human |
| S Tsuji, D Char, R P Bucy, M Simonsen, C H Chen, M D Coope. Gamma delta T cells are secondary participants in acute graft-versus-host reactions initiated by CD4+ alpha beta T cells. European journal of immunology. vol 26. issue 2. 1996-06-13. PMID:8617313. |
however, host gamma delta t cells were recruited into the donor alpha beta t cell-initiated lesions, where they were activated and induced to proliferate. |
1996-06-13 |
2023-08-12 |
human |
| P Tiffin, H Ashton, R Marsh, F Kamal. Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers. Psychopharmacology. vol 121. issue 4. 1996-06-12. PMID:8619015. |
prior to caffeine administration, poor sleepers compared to normal sleepers had faster heart rates, lower ratings for concentration and relaxation, poorer performance on the dsst, greater cnv magnitude, faster peak alpha frequency and lower delta, theta and beta power. |
1996-06-12 |
2023-08-12 |
Not clear |
| W R Waters, J A Har. Cryptosporidium parvum infection in T-cell receptor (TCR)-alpha- and TCR-delta-deficient mice. Infection and immunity. vol 64. issue 5. 1996-06-06. PMID:8613403. |
mice deficient in either alpha beta or gamma delta t cells were more susceptible to infection with the protozoan parasite cryptosporidium parvum than were control mice. |
1996-06-06 |
2023-08-12 |
mouse |
| W R Waters, J A Har. Cryptosporidium parvum infection in T-cell receptor (TCR)-alpha- and TCR-delta-deficient mice. Infection and immunity. vol 64. issue 5. 1996-06-06. PMID:8613403. |
these data indicate that alpha beta t cells are important for resistance to c. parvum while gamma delta t cells have a less critical role. |
1996-06-06 |
2023-08-12 |
mouse |
| V Luntz-Leybman, A Rotter, D Zdilar, A Frosthol. Uncoupling of GABAA/benzodiazepine receptor alpha 1, beta 2, and gamma 2 subunit mRNA expression in cerebellar Purkinje cells of staggerer mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 12. 1996-06-06. PMID:8613747. |
the mammalian gabaa/benzodiazepine (gabaa/bz) receptor is comprised of several subunit isoforms: alpha 1-6, beta 1-13, gamma 1-3 and delta. |
1996-06-06 |
2023-08-12 |
mouse |
| F Croquet, A Bréhier, S Gil, J Davy, J Fége. Five isoenzymes of protein kinase C are expressed in normal and STZ-diabetic rat hepatocytes: effect of phorbol 12-myristate 13-acetate. Biochimica et biophysica acta. vol 1315. issue 3. 1996-06-04. PMID:8611654. |
using isoenzyme-specific antisera, five protein kinase cs (pkcs) were detected in cytosol and membrane hepatocytes from normal rats: pkc alpha (80 kda), pkc beta ii (40, 50, 55, 85 kda), pkc delta (74, 76 kda), pkc epsilon (95 kda), pkc zeta (65, 70 kda). |
1996-06-04 |
2023-08-12 |
rat |