| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pamela M Greenwood, Ming-Kuan Lin, Ramya Sundararajan, Karl J Fryxell, Raja Parasurama. Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. Psychology and aging. vol 29. issue 2. 2015-03-18. PMID:24956005. |
since these genes encode enzymes influencing levels of extracellular dopamine, important for wm, we reasoned that individuals with low activity alleles of each snp (less efficient degradation of dopamine by comt and less efficient conversion of dopamine to norepinephrine by dbh) would have higher levels of extracellular dopamine and therefore better wm performance. |
2015-03-18 |
2023-08-13 |
Not clear |
| Pamela M Greenwood, Ming-Kuan Lin, Ramya Sundararajan, Karl J Fryxell, Raja Parasurama. Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. Psychology and aging. vol 29. issue 2. 2015-03-18. PMID:24956005. |
we found that age increased the combined effect on wm of the comt and dbh genes encoding enzymes controlling levels of extracellular dopamine. |
2015-03-18 |
2023-08-13 |
Not clear |
| Elizabeth S Barrie, David Weinshenker, Anurag Verma, Sarah A Pendergrass, Leslie A Lange, Marylyn D Ritchie, James G Wilson, Helena Kuivaniemi, Gerard Tromp, David J Carey, Glenn S Gerhard, Murray H Brilliant, Scott J Hebbring, Joseph F Cubells, Julia K Pinsonneault, Greg J Norman, Wolfgang Sade. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation research. vol 115. issue 12. 2015-02-12. PMID:25326128. |
dopamine β-hydroxylase (dbh) catalyzes the conversion of dopamine to norepinephrine in the central nervous system and peripherally. |
2015-02-12 |
2023-08-13 |
human |
| Piotr Chmielarz, Justyna Kuśmierczyk, Rosanna Parlato, Günther Schütz, Irena Nalepa, Grzegorz Kreine. Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety- and depressive-like behavior in mice. PloS one. vol 8. issue 8. 2015-01-22. PMID:23977333. |
we crossed transgenic mice expressing the cre recombinase under the dopamine beta-hydroxylase (dbh) promoter with animals harboring the floxed gr gene. |
2015-01-22 |
2023-08-12 |
mouse |
| Jonathan N Flak, Brent Myers, Matia B Solomon, Jessica M McKlveen, Eric G Krause, James P Herma. Role of paraventricular nucleus-projecting norepinephrine/epinephrine neurons in acute and chronic stress. The European journal of neuroscience. vol 39. issue 11. 2015-01-16. PMID:24766138. |
following intra-pvn injection of saporin toxin conjugated to a dopamine beta-hydroxylase (dbh) antibody (dsap), in rats pvn dbh immunoreactivity was almost completely eliminated, but immunoreactive afferents to other key regions involved in stress integration were spared (e.g. |
2015-01-16 |
2023-08-13 |
rat |
| Hortensia Alonso-Navarro, Felix Javier Jimenez-Jimenez, Elena Garcia-Martin, Jose A G Agunde. Genomic and pharmacogenomic biomarkers of Parkinson's disease. Current drug metabolism. vol 15. issue 2. 2014-11-24. PMID:24694231. |
nor did polymorphisms in genes related to dopamine or serotonin drd, dat, th, ddc, dbh, mao, comt, slc6a4, mtr, mthfr, oxidative stress noq1, noq2, mephx, hfe, gpx, cat, mnsod, hfe, ho-1, ho-2, nfe2l2, keap1, inflammatory processes, ils, tnf, act, nos, hnmt, abp1, hrhs, trophic and growth factors bdnf, fgf, or mitochondrial metabolism and function. |
2014-11-24 |
2023-08-13 |
cat |
| Miwa Komatsu, Nobuto Shibata, Tohru Ohnuma, Bolati Kuerban, Katrin Tomson, Aiko Toda, Yuko Tagata, Tomoko Nakada, Hiromi Shimazaki, Heii Ara. Polymorphisms in the aldehyde dehydrogenase 2 and dopamine β hydroxylase genes are not associated with Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 4. 2014-11-07. PMID:24201835. |
the activity of dopamine β hydroxylase (dbh) is reduced in the hippocampus and neocortex in the ad brain. |
2014-11-07 |
2023-08-12 |
Not clear |
| Hong-Bin Zhao, Hui Ma, Xiao-Qin Ha, Ping Zheng, Xiao-Yun Li, Ming Zhang, Ju-Zi Dong, Yin-Shu Yan. Salidroside induces rat mesenchymal stem cells to differentiate into dopaminergic neurons. Cell biology international. vol 38. issue 4. 2014-10-30. PMID:24323403. |
the expression of dopamine neurons markers, such as dopamine-beta-hydroxy (dbh), dopa decarboxylase (ddc) and tyrosine hydroxylase (th), was significantly upregulated after treatment with salidroside for 1-12 days. |
2014-10-30 |
2023-08-12 |
rat |
| Zenon Pidsudk. Immunohistochemical characteristics and distribution of neurons in the paravertebral, prevertebral and pelvic ganglia supplying the urinary bladder in the male pig. Journal of molecular neuroscience : MN. vol 52. issue 1. 2014-09-25. PMID:24122239. |
the combined retrograde tracing and immunohistochemistry for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin(som), galanin (gal), vasoactive intestinal polypeptide(vip), nitric oxide synthase (nos), calcitonin gene related peptide (cgrp), substance p (sp), choline acetyltransferase (chat) and vesicular acetylcholine transporter(vacht) were applied in the experiment. |
2014-09-25 |
2023-08-12 |
Not clear |
| Riadh Nciri, Ezzeddine Bourogaa, Samira Jbahi, Mohamed Salah Allagui, Abdelfattah Elfeki, Christian Vincent, Françoise Crout. Chronic neuroprotective effects of low concentration lithium on SH-SY5Y cells: possible involvement of stress proteins and gene expression. Neural regeneration research. vol 9. issue 7. 2014-09-10. PMID:25206881. |
cdna arrays showed that pyruvate kinase 2 (pkm2) and calmodulin 3 (cam 3) expression levels were significantly down-regulated, phosphatase protein pp2a expression was lightly down-regulated, and casein kinase ii (ck2), threonine/tyrosine phosphatase 7 (pyst2), and dopamine beta-hydroxylase (dbh) expression levels were significantly up-regulated. |
2014-09-10 |
2023-08-13 |
Not clear |
| Yan Wang, Phillip R Musich, Moises A Serrano, Yue Zou, Jia Zhang, Meng-Yang Zh. Effects of DSP4 on the noradrenergic phenotypes and its potential molecular mechanisms in SH-SY5Y cells. Neurotoxicity research. vol 25. issue 2. 2014-09-07. PMID:23996700. |
dopamine β-hydroxylase (dbh) and norepinephrine (ne) transporter (net) are the noradrenergic phenotypes for their functional importance to noradrenergic neurons. |
2014-09-07 |
2023-08-12 |
Not clear |
| C M Ragan, J S Lonstei. Differential postpartum sensitivity to the anxiety-modulating effects of offspring contact is associated with innate anxiety and brainstem levels of dopamine beta-hydroxylase in female laboratory rats. Neuroscience. vol 256. 2014-08-27. PMID:24161285. |
levels of dopamine β-hydroxylase (dbh, norepinephrine synthesizing enzyme) and tryptophan hydroxylase-2 (tph2, serotonin synthesizing enzyme) were measured in the brainstem and dorsal raphe, respectively. |
2014-08-27 |
2023-08-12 |
rat |
| Debra A Cooper, Heather L Kimmel, Daniel F Manvich, Karl T Schmidt, David Weinshenker, Leonard L Howel. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 350. issue 1. 2014-08-26. PMID:24817036. |
one of many biochemical actions of disulfiram is inhibition of dopamine β-hydroxylase (dbh), the enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons. |
2014-08-26 |
2023-08-13 |
rat |
| Hongqiang Sun, Fan Wang, Hongzhen Fan, Quanzhi Yan, Kaiyan Cui, Wei Yuan, Fushuai Zhao, Lili Zhao, Jie Yuan, Fude Yang, Thomas R Kosten, Xiang Yang Zhan. The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients. PloS one. vol 8. issue 8. 2014-08-21. PMID:23951054. |
previous studies have indicated that some genetic polymorphisms of immune system and dopamine beta-hydroxylase (dbh) genes may be involved in the pathogenesis of td. |
2014-08-21 |
2023-08-12 |
human |
| Nathan J VanDusen, Joshua W Vincentz, Beth A Firulli, Marthe J Howard, Michael Rubart, Anthony B Firull. Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Developmental biology. vol 388. issue 2. 2014-07-07. PMID:24565998. |
in both cases, hand2 loss-of-function dramatically reduces expression of dopamine beta hydroxylase (dbh), a gene encoding a crucial catecholaminergic biosynthetic enzyme. |
2014-07-07 |
2023-08-12 |
Not clear |
| Lorenza S Colzato, Mischa de Rover, Wery P M van den Wildenberg, Sander Nieuwenhui. Genetic marker of norepinephrine synthesis predicts individual differences in post-error slowing: a pilot study. Neuropsychologia. vol 51. issue 13. 2014-06-25. PMID:23962674. |
in a sample of 100 healthy adults, we studied the dependency of an individual's size of pes on the dbh5'-ins/del polymorphism-a variation in the dbh gene associated with the production of the enzyme dopamine β-hydroxylase, which catalyzes the conversion of dopamine to norepinephrine. |
2014-06-25 |
2023-08-12 |
Not clear |
| U W Preuss, F M Wurst, M Ridinger, D Rujescu, C Fehr, G Koller, B Bondy, N Wodarz, M Soyka, P Zil. Association of functional DBH genetic variants with alcohol dependence risk and related depression and suicide attempt phenotypes: results from a large multicenter association study. Drug and alcohol dependence. vol 133. issue 2. 2014-06-23. PMID:23906995. |
dopamine-beta-hydroxylase (dbh) metabolizes the conversion of dopamine to noradrenaline. |
2014-06-23 |
2023-08-12 |
Not clear |
| M Khalilur Rahman, M Iqbal Choudhary, M Arif, M Monzur Morshe. Dopamine-β-Hydroxylase Activity and Levels of Its Cofactors and Other Biochemical Parameters in the Serum of Arsenicosis Patients of Bangladesh. International journal of biomedical science : IJBS. vol 10. issue 1. 2014-04-08. PMID:24711750. |
dopamine-β-hydroxylase (dbh) is a neurotransmitter (catecholamine)-mediating enzyme, which catalyzes the formation of norepinephrine from dopamine. |
2014-04-08 |
2023-08-13 |
Not clear |
| Z Pidsudk. Immunohistochemical characteristics and distribution of neurons in the intramural ganglia supplying the urinary bladder in the male pig. Polish journal of veterinary sciences. vol 16. issue 4. 2014-04-03. PMID:24597296. |
twelve tm-thick cryostat sections were processed for double-labelling immunofluorescence with antibodies against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), calcitonin gene-related peptide (cgrp), substance p (sp) and vesicular acetylcholine transporter (vacht). |
2014-04-03 |
2023-08-12 |
Not clear |
| Yan Fan, Ping Chen, Ying Li, Kui Cui, Daniel M Noel, Elizabeth D Cummins, Daniel J Peterson, Russell W Brown, Meng-Yang Zh. Corticosterone administration up-regulated expression of norepinephrine transporter and dopamine β-hydroxylase in rat locus coeruleus and its terminal regions. Journal of neurochemistry. vol 128. issue 3. 2014-03-12. PMID:24111919. |
in situ hybridization measurements showed that cort ingestion significantly increased mrna levels of norepinephrine transporter (net) and dopamine β-hydroxylase (dbh) in the lc region. |
2014-03-12 |
2023-08-12 |
rat |