| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bruno Igreja, Nuno Pires, Ana Loureiro, Lyndon Wright, Patrício Soares-da-Silv. Cardiometabolic and Inflammatory Benefits of Sympathetic Down-Regulation with Zamicastat in Aged Spontaneously Hypertensive Rats. ACS pharmacology & translational science. vol 2. issue 5. 2020-09-28. PMID:32259069. |
one strategy to mitigate the sns overdrive is by restricting the biosynthesis of norepinephrine via the inhibition of dopamine β-hydroxylase (dbh). |
2020-09-28 |
2023-08-13 |
rat |
| Bruno Igreja, Nuno Pires, Ana Loureiro, Lyndon Wright, Patrício Soares-da-Silv. Cardiometabolic and Inflammatory Benefits of Sympathetic Down-Regulation with Zamicastat in Aged Spontaneously Hypertensive Rats. ACS pharmacology & translational science. vol 2. issue 5. 2020-09-28. PMID:32259069. |
zamicastat is a new dbh inhibitor that decreases norepinephrine and increases dopamine levels in peripherally sympathetic-innervated tissues. |
2020-09-28 |
2023-08-13 |
rat |
| Caroline E Boyle, Anjum Parkar, Amanda Barror, Leszek Kubi. Noradrenergic terminal density varies among different groups of hypoglossal premotor neurons. Journal of chemical neuroanatomy. vol 100. 2020-09-11. PMID:31128245. |
we then used dual immunohistochemistry and brightfield microscopy to count dopamine beta-hydroxylase (dbh)-positive axon terminals closely apposed to ctb cells located in five anatomically distinct xii premotor regions. |
2020-09-11 |
2023-08-13 |
rat |
| Anna Vavřínová, Michal Behuliak, Michal Bencze, Ivana Vaněčková, Josef Zich. Which sympathoadrenal abnormalities of adult spontaneously hypertensive rats can be traced to a prehypertensive stage? Hypertension research : official journal of the Japanese Society of Hypertension. vol 42. issue 7. 2020-09-08. PMID:30651588. |
in the adrenal glands of adult shr, the expression of catecholamine biosynthetic enzymes th, ddc, dbh and pnmt was decreased along the amounts of dopamine and noradrenaline (50% and 38%, respectively, p < 0.001). |
2020-09-08 |
2023-08-13 |
rat |
| Shubhrajit Roy, Sampurna Ghosh, Sreyashi Bhattacharya, Arpan Saha, Shyamal Kumar Das, Prasanta Kumar Gangopadhyay, Ashish Bavdekar, Kunal Ray, Mainak Sengupta, Jharna Ra. Dopamine β hydroxylase (DBH) polymorphisms do not contribute towards the clinical course of Wilson's disease in Indian patients. The journal of gene medicine. vol 21. issue 9. 2020-07-17. PMID:31265749. |
dopamine β hydroxylase (dbh) polymorphisms do not contribute towards the clinical course of wilson's disease in indian patients. |
2020-07-17 |
2023-08-13 |
Not clear |
| Shubhrajit Roy, Sampurna Ghosh, Sreyashi Bhattacharya, Arpan Saha, Shyamal Kumar Das, Prasanta Kumar Gangopadhyay, Ashish Bavdekar, Kunal Ray, Mainak Sengupta, Jharna Ra. Dopamine β hydroxylase (DBH) polymorphisms do not contribute towards the clinical course of Wilson's disease in Indian patients. The journal of gene medicine. vol 21. issue 9. 2020-07-17. PMID:31265749. |
dopamine β hydroxylase (dbh) encodes a copper-dependent mono-oxygenase that converts dopamine to norepinephrine, thereby regulating the endogenous dopamine content in the neurons. |
2020-07-17 |
2023-08-13 |
Not clear |
| Pang Tao, Zhao Jing, Gao Shou-Hong, Piao Shu-Juan, Jiao Jian-Peng, Lu Wen-Quan, Chen Wan-Shen. Effects of leptin on norepinephrine in acute ischemic stroke. Die Pharmazie. vol 74. issue 8. 2020-06-11. PMID:31526440. |
leptin administration increased noradrenaline concentration and dopamine β-monooxygenase (dbh) but decreased noradrenaline transporter (net) expression in primary cerebral neurons. |
2020-06-11 |
2023-08-13 |
mouse |
| R Yoshiyuki Osamura, O Yasuda, K Kawai, S Hori, H Suemizu, N Onoda, Tong H Jo. Immunohistochemical localization of catecholamine-synthesizing enzymes in human pheochromocytomas. Endocrine pathology. vol 1. issue 2. 2020-05-04. PMID:32357604. |
a total of 17 (10 adrenal and 7 extraadrenal) pheochromocytomas were examined immunohistochemically for the localization of catecholamine-synthesizing enzymes-tyrosine hydroxylase (th), dopamine β-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt)-as well as the marker peptides for pheochrornocytomas (i.e., met-enkephalin-arggly-leu [meagl]). |
2020-05-04 |
2023-08-13 |
human |
| Wiebke Bensmann, Nicolas Zink, Larissa Arning, Christian Beste, Ann-Kathrin Stoc. The Presynaptic Regulation of Dopamine and Norepinephrine Synthesis Has Dissociable Effects on Different Kinds of Cognitive Conflicts. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31183808. |
we investigated the effects of presynaptic differences in dopamine and norepinephrine synthesis with the help of the tyrosine hydroxylase (th) rs10770141 and the dopamine-β-hydroxylase (dbh) rs1611115, rs6271, and rs1611122 polymorphisms. |
2020-04-06 |
2023-08-13 |
human |
| Armaz Aschrafi, Adama Berndt, Jeffrey A Kowalak, Jenna R Gale, Anthony E Gioio, Barry B Kapla. Angiotensin II mediates the axonal trafficking of tyrosine hydroxylase and dopamine β-hydroxylase mRNAs and enhances norepinephrine synthesis in primary sympathetic neurons. Journal of neurochemistry. vol 150. issue 6. 2020-03-23. PMID:31306490. |
in the present study, the hypothesis was tested that ang ii induces ne synthesis in rat primary scg neurons via the modulation of the trafficking of the mrnas encoding the catecholamine synthesizing enzymes th and dopamine β-hydroxylase (dbh). |
2020-03-23 |
2023-08-13 |
rat |
| Zhijuan Wang, Yedan Gai, Jinlian Zhou, Jiali Liu, Sheng Cu. miR-375 mediates the CRF signaling pathway to regulate catecholamine biosynthesis by targeting Sp1 in porcine adrenal gland. Stress (Amsterdam, Netherlands). vol 22. issue 3. 2020-02-18. PMID:30714474. |
functional studies showed that mir-375 negatively regulated cats synthesis in primary cells by affecting the expression of the cats synthetases tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine-n-methyltransferase (pnmt). |
2020-02-18 |
2023-08-13 |
mouse |
| Arunibha Ghosh, Tamal Sadhukhan, Subhajit Giri, Arindam Biswas, Shyamal Kumar Das, Kunal Ray, Jharna Ra. Dopamine β Hydroxylase (DBH) is a potential modifier gene associated with Parkinson's disease in Eastern India. Neuroscience letters. vol 706. 2019-12-27. PMID:31082450. |
dopamine β hydroxylase (dbh) is a potential modifier gene associated with parkinson's disease in eastern india. |
2019-12-27 |
2023-08-13 |
Not clear |
| Arunibha Ghosh, Tamal Sadhukhan, Subhajit Giri, Arindam Biswas, Shyamal Kumar Das, Kunal Ray, Jharna Ra. Dopamine β Hydroxylase (DBH) is a potential modifier gene associated with Parkinson's disease in Eastern India. Neuroscience letters. vol 706. 2019-12-27. PMID:31082450. |
the dopamine β-hydroxylase (dbh) maintains cellular dopamine content and regulates dopamine turn over in neurons. |
2019-12-27 |
2023-08-13 |
Not clear |
| Z Pidsudko, Ż Listowska, A Franke-Radowiecka, M Klimczuk, M Załęcki, J Kaleczy. Distribution and chemical coding of urinary bladder apex-projecting neurons in aorticorenal and testicular ganglia of the male pig. Polish journal of veterinary sciences. vol 22. issue 2. 2019-12-09. PMID:31269360. |
the presence of tyrosine hydroxylase (th) or dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), nitric oxide synthase (nos) and vesicular acetylcholine transporter (vacht) were investigated. |
2019-12-09 |
2023-08-13 |
Not clear |
| Carla L Busceti, Rosangela Ferese, Domenico Bucci, Larisa Ryskalin, Stefano Gambardella, Michele Madonna, Ferdinando Nicoletti, Francesco Forna. Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures. International journal of molecular sciences. vol 20. issue 12. 2019-11-27. PMID:31197099. |
on the other hand, dopamine beta-hydroxylase (dbh) increases only after very high doses of corticosterone. |
2019-11-27 |
2023-08-13 |
mouse |
| J Kuchinka, Monika Chrzanowska, T Kude. Adrenergic and cholinergic innervation of the atrioventricular valves in chinchilla (Chinchilla laniger). Folia morphologica. vol 76. issue 4. 2019-11-20. PMID:28553858. |
double immunocytochemical staining was also used for the expression of vesicular acetylcholine transporter (vacht) and dopamine beta hydroxylase (dbh). |
2019-11-20 |
2023-08-13 |
Not clear |
| T R A Mercado, C A Fontes Ribeiro, T Morgadinho, M A V Abre. Influence of Concurrent Heroin and Cocaine Abuse on the Adrenergic and Serotonergic Systems in Man Annals of the New York Academy of Sciences. vol 844. issue 1. 2019-11-20. PMID:29090807. |
free and sulfoconjugated catecholamines and serotonin (5-hydroxytryptamine, 5-ht) were measured by high-performance liquid chromatography with electrochemical detection (hplc-ecd); plasma dopamine (da)-b-hydroxylase (dbh) activity was determined by a hplc technique. |
2019-11-20 |
2023-08-13 |
human |
| A R Murtazina, Yu O Nikishina, L K Dil'mukhametova, A Ya Sapronova, M V Ugrumo. The Role of the Brain in the Regulation of Peripheral Noradrenaline-producing Organs in Rats During Morphogenesis. Doklady. Biochemistry and biophysics. vol 486. issue 1. 2019-08-29. PMID:31367831. |
in this study, we used a rat model that allowed blocking the synthesis of noradrenalin in the brain and evaluated gene expression and protein levels of noradrenaline key synthesis enzymes such as tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) in peripheral noradrenaline-producing organs. |
2019-08-29 |
2023-08-13 |
rat |
| Chikaya Deura, Shiori Minabe, Kana Ikegami, Naoko Inoue, Yoshihisa Uenoyama, Kei-Ichiro Maeda, Hiroko Tsukamur. Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons. The Journal of reproduction and development. vol 65. issue 2. 2019-08-28. PMID:30662010. |
48 h after the wga injection, brain sections were taken from the forebrain, midbrain and hindbrain and subjected to double immunohistochemistry for wga and dopamine β-hydroxylase (dbh) or crh. |
2019-08-28 |
2023-08-13 |
rat |
| Caroline S Johnson, Jaideep S Bains, Alan G Watt. Neurotransmitter diversity in pre-synaptic terminals located in the parvicellular neuroendocrine paraventricular nucleus of the rat and mouse hypothalamus. The Journal of comparative neurology. vol 526. issue 8. 2019-06-26. PMID:29424419. |
here we use immunohistochemistry with high-resolution 3-dimensional image analyses to examine the arrangement of single- and co-occurring gaba, glutamate, and catecholamine markers in synaptophysin-defined pre-synaptic terminals in the pvhmpd of unstressed rats and crh-ires-cre;ai14 transgenic mice: respectively, vesicular glutamate transporter 2 (vglut2), vesicular gaba transporter (vgat), dopamine β-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt). |
2019-06-26 |
2023-08-13 |
mouse |