| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pierre-Olivier Gaudreault, Sarah G King, Pias Malaker, Nelly Alia-Klein, Rita Z Goldstei. Whole-brain white matter abnormalities in human cocaine and heroin use disorders: association with craving, recency, and cumulative use. Molecular psychiatry. 2022-11-12. PMID:36369361. |
our study assessed whole-brain wm integrity in three subgroups of individuals addicted to drugs, encompassing those with cocaine (cud) or heroin (hud) use disorder, compared to healthy controls (ctl). |
2022-11-12 |
2023-08-14 |
human |
| Verica Milivojevic, Lily Charron, Nia Fogelman, Gretchen Hermes, Rajita Sinh. Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. Biomolecules. vol 12. issue 11. 2022-11-11. PMID:36358943. |
this study tested whether potentiation of the neuroactive steroid system with the precursor pregnenolone (preg) affects stress- and cue-induced cocaine craving, anxiety and autonomic response in individuals with cocaine use disorder (cud). |
2022-11-11 |
2023-08-14 |
human |
| Verica Milivojevic, Lily Charron, Nia Fogelman, Gretchen Hermes, Rajita Sinh. Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. Biomolecules. vol 12. issue 11. 2022-11-11. PMID:36358943. |
findings indicate that pregnenolone decreases stress- and cocaine cue-provoked craving and anxiety and reduces stress-induced autonomic arousal in individuals with cud. |
2022-11-11 |
2023-08-14 |
human |
| Elise E DeVito, James Poling, Theresa Babuscio, Charla Nich, Kathleen M Carroll, Mehmet Sofuogl. Modafinil Does Not Reduce Cocaine Use in Methadone-Maintained Individuals. Drug and alcohol dependence reports. vol 2. 2022-10-31. PMID:36310662. |
there are no approved medications for the treatment of cocaine use disorder (cud). |
2022-10-31 |
2023-08-14 |
Not clear |
| Sarah A Schoenrock, Leona Gagnon, Ashley Olson, Michael Leonardo, Vivek M Philip, Hao He, Laura G Reinholdt, Stacey J Sukoff Rizzo, James D Jentsch, Elissa J Chesler, Lisa M Tarantin. The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization. Frontiers in behavioral neuroscience. vol 16. 2022-10-24. PMID:36275853. |
despite the prevalence of cocaine use disorder (cud) and the personal and societal problems it presents, there are currently no approved pharmaceutical treatments. |
2022-10-24 |
2023-08-14 |
mouse |
| Lauren S Bailey, Jared R Bagley, James D Wherry, Elissa J Chesler, Anushree Karkhanis, James D Jentsch, Lisa M Tarantin. Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice. Psychopharmacology. 2022-10-14. PMID:36239767. |
cocaine use disorder (cud) is a highly heritable form of substance use disorder, with genetic variation accounting for a substantial proportion of the risk for transitioning from recreational use to a clinically impairing addiction. |
2022-10-14 |
2023-08-14 |
mouse |
| Ahmet O Ceceli, Yuefeng Huang, Greg Kronberg, Pias Malaker, Pazia Miller, Sarah King, Pierre Olivier Gaudreault, Natalie McClain, Lily Gabay, Devarshi Vasa, Jeffrey H Newcorn, Defne Ekin, Nelly Alia-Klein, Rita Z Goldstei. Common and distinct fronto-striatal volumetric changes in heroin and cocaine use disorders. Brain : a journal of neurology. 2022-10-06. PMID:36200376. |
we hypothesized parallel gray matter volume (gmv) changes associated with human heroin or cocaine use disorder (hud/cud): lower gmv of vmpfc/nacc in hud and ifg in cud, and putamen gmv to be associated with addiction severity measures (including craving) across both. |
2022-10-06 |
2023-08-14 |
human |
| Elizabeth K C Schwartz, Noah R Wolkowicz, Joao P De Aquino, R Ross MacLean, Mehmet Sofuogl. Cocaine Use Disorder (CUD): Current Clinical Perspectives. Substance abuse and rehabilitation. vol 13. 2022-09-12. PMID:36093428. |
cocaine use disorder (cud): current clinical perspectives. |
2022-09-12 |
2023-08-14 |
Not clear |
| Elizabeth K C Schwartz, Noah R Wolkowicz, Joao P De Aquino, R Ross MacLean, Mehmet Sofuogl. Cocaine Use Disorder (CUD): Current Clinical Perspectives. Substance abuse and rehabilitation. vol 13. 2022-09-12. PMID:36093428. |
cocaine use disorder (cud) is a devastating disorder, impacting both individuals and society. |
2022-09-12 |
2023-08-14 |
Not clear |
| Elizabeth K C Schwartz, Noah R Wolkowicz, Joao P De Aquino, R Ross MacLean, Mehmet Sofuogl. Cocaine Use Disorder (CUD): Current Clinical Perspectives. Substance abuse and rehabilitation. vol 13. 2022-09-12. PMID:36093428. |
in this review, we provide an overview of cud, including risk factors for cud, common co-occurring disorders, acute and chronic effects of cocaine use, and currently available pharmacological and behavioral treatments. |
2022-09-12 |
2023-08-14 |
Not clear |
| Jane E Joseph, Nicholas Bustos, Kathleen Crum, Julianne Flanagan, Nathaniel L Baker, Karen Hartwell, Megan Moran Santa-Maria, Kathleen Brady, Aimee McRae-Clar. Oxytocin moderates corticolimbic social stress reactivity in cocaine use disorder and healthy controls. Comprehensive psychoneuroendocrinology. vol 11. 2022-08-15. PMID:35967924. |
the present study examined the effect of intransasal ot (24 iu) versus placebo (pbo) on corticolimbic functional connectivity associated with acute social stress in individuals with cocaine use disorder (cud; n = 67) and healthy controls (hc; n = 52). |
2022-08-15 |
2023-08-14 |
Not clear |
| Andrea Miuli, Gianluca Mancusi, Mauro Pettorruso, Francesco Di Carlo, Katia Clemente, Ilenia Di Meo, Antea d'Andrea, Giulia Pernaci, Teresa Di Crosta, Giacomo d'Andrea, Giovanna Bubbico, Giovanni Martinotti, Massimo di Giannantoni. Impact of sleep disorders and disease duration on neurotrophins levels in cocaine use disorder. Neuroscience letters. 2022-07-19. PMID:35850320. |
convergent lines of evidence suggest neurotrophins alterations could be involved into the pathophysiology of cocaine use disorder (cud) and insomnia. |
2022-07-19 |
2023-08-14 |
Not clear |
| Wenchao Li, Chun Zhang, Yang Yang Wang, Lifei Xiao, Yan Feng, Xianhao Huo, Chaofan Wang, Yu Sun, Feng Wang, Tao Su. Alterations of RNAs in the insula related to cocaine-induced condition place preference in adolescent mice. Biochemical and biophysical research communications. vol 621. 2022-07-12. PMID:35820280. |
it reminds us that cocaine may have a potential role in post-transcriptional regulation, but the alteration of insula-expression profile in adolescent cocaine use disorder (cud) has not been reported. |
2022-07-12 |
2023-08-14 |
mouse |
| Andrea Cippitelli, Gilles Zribi, Lawrence Tol. PPL-103: A mixed opioid partial agonist with desirable anti-cocaine properties. Progress in neuro-psychopharmacology & biological psychiatry. 2022-07-07. PMID:35798174. |
cocaine use disorder (cud) is a persistent public health problem for which no effective medications are available. |
2022-07-07 |
2023-08-14 |
rat |
| Andrea Cippitelli, Gilles Zribi, Lawrence Tol. PPL-103: A mixed opioid partial agonist with desirable anti-cocaine properties. Progress in neuro-psychopharmacology & biological psychiatry. 2022-07-07. PMID:35798174. |
because chronic cocaine use induces changes in the kappa opioid receptor/dynorphin system, we hypothesized that a kappa partial agonist, such as ppl-103, would attenuate the aversive properties of the upregulated kappa system, resulting in effective treatment approach for cud. |
2022-07-07 |
2023-08-14 |
rat |
| Andrea Cippitelli, Gilles Zribi, Lawrence Tol. PPL-103: A mixed opioid partial agonist with desirable anti-cocaine properties. Progress in neuro-psychopharmacology & biological psychiatry. 2022-07-07. PMID:35798174. |
we tested the effects of ppl-103 on cocaine self-administration models that recapitulate core aspects of cud in humans. |
2022-07-07 |
2023-08-14 |
rat |
| Fang Zheng, Zhenyu Jin, Jing Deng, Xiabin Chen, Xirong Zheng, Guojun Wang, Kyungbo Kim, Linyue Shang, Ziyuan Zhou, Chang-Guo Zha. Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism. Bioconjugate chemistry. 2022-06-29. PMID:35767675. |
it is particularly challenging to develop a truly effective pharmacotherapy for cocaine use disorder (cud) treatment. |
2022-06-29 |
2023-08-14 |
Not clear |
| María Flores-López, Nuria García-Marchena, Pedro Araos, Nerea Requena-Ocaña, Oscar Porras-Perales, Sandra Torres-Galván, Juan Suarez, Nieves Pizarro, Rafael de la Torre, Gabriel Rubio, Juan Jesús Ruiz-Ruiz, Fernando Rodríguez de Fonseca, Antonia Serrano, Francisco Javier Pavón-Moró. Sex Differences in Plasma Lysophosphatidic Acid Species in Patients with Alcohol and Cocaine Use Disorders. Brain sciences. vol 12. issue 5. 2022-05-28. PMID:35624975. |
the sud group was divided according to the diagnosis of aud and/or cocaine use disorder (cud). |
2022-05-28 |
2023-08-13 |
human |
| Nuria García-Marchena, Alberto Marcos, María Flores-López, Mario Moreno-Fernández, Nerea Requena-Ocaña, Oscar Porras-Perales, Sandra Torres-Galván, Pedro Araos, Antonia Serrano, Roberto Muga, Juan Jesús Ruiz-Ruiz, Fernando Rodríguez de Fonseca, Emilio Ambrosio, Francisco Javier Pavón-Moró. Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625874. |
because most psychiatric disorders and biomarkers show sex differences, we investigated amino acids in men and women with alcohol and/or cocaine use disorders (aud and/or cud) and psychiatric comorbidity. |
2022-05-28 |
2023-08-13 |
human |
| Christiann H Gaines, Sarah A Schoenrock, Joseph Farrington, David F Lee, Lucas J Aponte-Collazo, Ginger D Shaw, Darla R Miller, Martin T Ferris, Fernando Pardo-Manuel de Villena, Lisa M Tarantin. Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains. Frontiers in psychiatry. vol 13. 2022-05-23. PMID:35599758. |
cocaine use disorders (cud) are devastating for affected individuals and impose a significant societal burden, but there are currently no fda-approved therapies. |
2022-05-23 |
2023-08-13 |
mouse |