| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaqueline B Schuch, Natália Becker, Francisco Diego Rabelo-da-Ponte, Felipe Ornell, Hellen J M Freitas, Fernando P Rebelatto, Anne O Sordi, Flavio Pechansky, Lisia von Diemen, Felix H P Kessle. Assessment of cognitive functioning using the Mini Mental State Examination in men with Alcohol and Crack Cocaine Use Disorder. Trends in psychiatry and psychotherapy. 2023-03-08. PMID:36889679. |
our aim was to evaluate the cognitive performance of individuals with alcohol and/or crack cocaine use disorder (aud, cud, and polysubstance use) using the mmse, and to investigate the impact of substance use profile, and the moderation effect of educational level on mmse performance. |
2023-03-08 |
2023-08-14 |
Not clear |
| Eric Poisel, Lea Zillich, Fabian Streit, Josef Frank, Marion M Friske, Jerome C Foo, Naguib Mechawar, Gustavo Turecki, Anita C Hansson, Markus M Nöthen, Marcella Rietschel, Rainer Spanagel, Stephanie H Wit. DNA methylation in cocaine use disorder-An epigenome-wide approach in the human prefrontal cortex. Frontiers in psychiatry. vol 14. 2023-03-03. PMID:36865068. |
cocaine use disorder (cud) is characterized by a loss of control over cocaine intake and is associated with structural, functional, and molecular alterations in the human brain. |
2023-03-03 |
2023-08-14 |
human |
| Giselle A Funchal, Jaqueline B Schuch, Aline Zaparte, Breno Sanvicente-Vieira, Thiago W Viola, Rodrigo Grassi-Oliveira, Moisés E Baue. COCAINE USE DISORDER AND CHILDHOOD MALTREATMENT ARE ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS AND INCREASED INFLAMMATION. Acta neuropsychiatrica. 2023-02-27. PMID:36847141. |
cocaine use disorder (cud) has been associated with early life adversity and activated cellular immune responses. |
2023-02-27 |
2023-08-14 |
Not clear |
| Brian Sabato, Paulo Sérgio de Almeida Augusto, Raissa Lima Gonçalves Pereira, Felipe Coutinho Batista Esteves, Sordaini M Caligiorne, Bruna Rodrigues Dias Assis, Sóstenes Apolo Correia Marcelino, Larissa Pires do Espírito Santo, Karine Dias Dos Reis, Leonardo Da Silva Neto, Gisele Goulart, Ângelo de Fátima, Felipe Pierezan, Ricardo Toshio Fujiwara, Maila Castro, Frederico Garci. Safety and immunogenicity of the anti-cocaine vaccine UFMG-VAC-V4N2 in a non-human primate model. Vaccine. 2023-02-23. PMID:36822966. |
our research group developed a new vaccine candidate, the ufmg-v4n2, to treat cocaine use disorders (cud) using an innovative carrier based on calixarenes. |
2023-02-23 |
2023-08-14 |
Not clear |
| Luba Yammine, Jessica C Balderas, Michael F Weaver, Joy M Schmit. Feasibility of Exenatide, a GLP-1R Agonist, for Treating Cocaine Use Disorder: A Case Series Study. Journal of addiction medicine. 2023-02-17. PMID:36799773. |
no medications have yet been proven to be effective for the treatment of cocaine use disorder (cud). |
2023-02-17 |
2023-08-14 |
human |
| Zhenxiang Gao, T John Winhusen, Maria Gorenflo, Udi E Ghitza, Pamela B Davis, David C Kaelber, Rong X. Repurposing ketamine to treat cocaine use disorder: Integration of artificial intelligence-based prediction, expert evaluation, clinical corroboration, and mechanism of action analyses. Addiction (Abingdon, England). 2023-02-15. PMID:36792381. |
cocaine use disorder (cud) is a significant public health issue for which there is no food and drug administration (fda) approved medication. |
2023-02-15 |
2023-08-14 |
Not clear |
| Michal M Graczyk, Barbara J Sahakian, Trevor W Robbins, Karen D Ersch. Genotype-by-diagnosis interaction influences self-control in human cocaine addiction. Translational psychiatry. vol 13. issue 1. 2023-02-11. PMID:36774338. |
patients with cocaine use disorder (cud, n = 79) and healthy unrelated participants with no history of drug abuse (n = 54) completed the stop-signal task. |
2023-02-11 |
2023-08-14 |
human |
| Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestle. Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances. vol 9. issue 6. 2023-02-10. PMID:36763659. |
cocaine use disorder (cud) is an intractable syndrome, and rising overdose death rates represent a substantial public health crisis that exacts tremendous personal and financial costs on patients and society. |
2023-02-10 |
2023-08-14 |
mouse |
| Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestle. Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances. vol 9. issue 6. 2023-02-10. PMID:36763659. |
integration of comprehensive transcriptomic datasets from mouse cocaine self-administration models revealed evolutionarily conserved gene networks in cud that implicate especially d1 medium spiny neurons as drivers of cocaine-induced plasticity. |
2023-02-10 |
2023-08-14 |
mouse |
| Christina R Merritt, Ashley E Smith, Kamil Khanipov, George Golovko, Kelly T Dineley, Noelle C Anastasio, Kathryn A Cunningha. Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex. Frontiers in pharmacology. vol 13. 2023-01-02. PMID:36588704. |
drug overdose deaths involving cocaine have skyrocketed, an outcome attributable in part to the lack of fda-approved medications for the treatment of cocaine use disorder (cud), highlighting the need to identify new pharmacotherapeutic targets. |
2023-01-02 |
2023-08-14 |
rat |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
cocaine use disorder (cud) is closely associated with brain structure alterations, which are mainly analyzed using voxel-based morphometric and traditional volumetric methods with certain limitations. |
2022-12-29 |
2023-08-14 |
Not clear |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
this study conducted vertex-wise shape analysis to examine the effects of cocaine use on surface-based alterations of the basal ganglia in cud. |
2022-12-29 |
2023-08-14 |
Not clear |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
related to hcs, cud individuals showed regional surface atrophy of the left medial anterior thalamus, right medial posterior thalamus, and right dorsal anterior caudate, which were found to exhibit more significant surface atrophy in cud individuals with onset age of cocaine use below 18. |
2022-12-29 |
2023-08-14 |
Not clear |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
furthermore, surface-based alteration of the right dorsal anterior caudate was significantly associated with years of cocaine use and the onset age of cocaine use in cud individuals. |
2022-12-29 |
2023-08-14 |
Not clear |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
furthermore, both cud individuals with onset age of cocaine use below 18 and cud individuals with onset age of cocaine use above 18 showed similar significant relationship patterns between regional surface alteration of right dorsal anterior caudate and the onset age of cocaine use. |
2022-12-29 |
2023-08-14 |
Not clear |
| Hui Xu, Cheng Xu, Chenguang Gu. Cocaine use disorder is associated with widespread surface-based alterations of the basal ganglia. Journal of psychiatric research. vol 158. 2022-12-29. PMID:36580868. |
these findings shed light on the effect of cocaine use on basal ganglia, help us understand the neural basis of cocaine dependence, and further provide effective interventions for cud. |
2022-12-29 |
2023-08-14 |
Not clear |
| Omeed Rahimi, Jianjing Cao, Jenny Lam, Steven R Childers, Rana Rais, Linda J Porrino, Amy Newman, Michael A Nade. The Journal of pharmacology and experimental therapeutics. 2022-12-12. PMID:36507847. |
while there are no fda-approved treatments for cocaine use disorder (cud), several modafinil analogs have demonstrated promise in reducing cocaine self-administration and reinstatement in rats. |
2022-12-12 |
2023-08-14 |
rat |
| Angela Sanna, Valentina Bini, Paola Badas, Giorgio Corona, Gabriele Sanna, Lara Marcasciano, Maria Chiara De Vivo, Marco Dian. Role of maintenance treatment on long-term efficacy of bilateral iTBS of the prefrontal cortex in treatment-seeking cocaine addicts: A retrospective analysis. Frontiers in psychiatry. vol 13. 2022-11-25. PMID:36424992. |
this study explores the long-term outcome of bilateral intermittent theta-burst stimulation (itbs) of the prefrontal cortex (pfc) in cocaine use disorder (cud) and the possible influence of maintenance treatment in improving abstinence and decreasing do rates. |
2022-11-25 |
2023-08-14 |
Not clear |
| Augusto Martins Lucas Bittencourt, Bárbara Luiza Belmonte da Silveira, Lucca Pizzato Tondo, Leonardo Melo Rothmann, Alexandre Rosa Franco, Pedro Eugenio Mazzucchi Santana Ferreira, Thiago Wendt Viola, Rodrigo Grassi-Oliveir. Cingulate cortical thickness in cocaine use disorder: mediation effect between early life stress and cocaine consumption. Acta neuropsychiatrica. 2022-11-23. PMID:36416534. |
early-life stress (els) is an important moderator of cocaine use disorder (cud). |
2022-11-23 |
2023-08-14 |
Not clear |
| Joanna Jastrzębska, Małgorzata Frankowska, Irena Smaga, Magdalena Hubalewska-Mazgaj, Agata Suder, Renata Pieniążek, Edmund Przegaliński, Małgorzata Fili. Evaluation of the 5-HT Pharmacological reports : PR. 2022-11-14. PMID:36374478. |
evaluation of the 5-ht epidemiological data indicate a high rate of comorbidity of depression and cocaine use disorder (cud). |
2022-11-14 |
2023-08-14 |
Not clear |