| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naveen Sendhilnathan, Anna Ipata, Michael E Goldber. Mid-lateral cerebellar complex spikes encode multiple independent reward-related signals during reinforcement learning. Nature communications. vol 12. issue 1. 2021-11-24. PMID:34753927. |
although the cerebellum has been implicated in simple reward-based learning recently, the role of complex spikes (cs) and simple spikes (ss), their interaction and their relationship to complex reinforcement learning and decision making is still unclear. |
2021-11-24 |
2023-08-13 |
Not clear |
| Naveen Sendhilnathan, Anna Ipata, Michael E Goldber. Mid-lateral cerebellar complex spikes encode multiple independent reward-related signals during reinforcement learning. Nature communications. vol 12. issue 1. 2021-11-24. PMID:34753927. |
in a different context, cs from the same cerebellar area also responded in a cell-type and learning independent manner to the stimulus that signaled the beginning of the trial. |
2021-11-24 |
2023-08-13 |
Not clear |
| Neil P M Todd, Sendhil Govender, James G Colebatc. Non-invasive recording from the human cerebellum during a classical conditioning paradigm using the otolith-evoked blink reflex. Neuroscience letters. vol 765. 2021-11-08. PMID:34582972. |
the emg associated with the eyeblink for the ur occurred at a similar time to the expected post-cfr pause in the spontaneous cerebellar activity, or electrocerebellogram (eceg), while hypothesised conditioned pausing in the eceg was also observed in cs alone trials. |
2021-11-08 |
2023-08-13 |
human |
| Adrian Handforth, Eric J Lan. Increased Purkinje Cell Complex Spike and Deep Cerebellar Nucleus Synchrony as a Potential Basis for Syndromic Essential Tremor. A Review and Synthesis of the Literature. Cerebellum (London, England). vol 20. issue 2. 2021-11-05. PMID:33048308. |
we searched pubmed for papers describing factors that affect cs synchrony or cerebellar circuits potentially related to tremor. |
2021-11-05 |
2023-08-13 |
rat |
| Shinji Kakei, Mario Manto, Hirokazu Tanaka, Hiroshi Mitom. Pathophysiology of Cerebellar Tremor: The Forward Model-Related Tremor and the Inferior Olive Oscillation-Related Tremor. Frontiers in neurology. vol 12. 2021-07-16. PMID:34262527. |
although this type of regular tremor does not necessarily accompany ataxia, the aberrant io activities (i.e., aberrant cs activities) may induce secondary maladaptation of cerebellar forward models through aberrant patterns of long-term depression (ltd) and/or long-term potentiation (ltp) of the cerebellar circuitry. |
2021-07-16 |
2023-08-13 |
Not clear |
| Adam B Steinmetz, John H Freema. Intracerebellar cannabinoid administration impairs delay but not trace eyeblink conditioning. Behavioural brain research. vol 378. 2021-04-28. PMID:31560921. |
to more precisely assess the effects of cannabinoids on cerebellar learning mechanisms the current study examined the effects of the cannabinoid agonist win55,212-2 (win) infusion into the area of the cerebellar cortex necessary for ebc (the eyeblink microzone) in rats during short delay (250 ms cs), long delay (750 ms cs), and trace (250 ms cs, 500 ms trace interval) ebc. |
2021-04-28 |
2023-08-13 |
rat |
| Da-Bing Li, Juan Yao, Lin Sun, Bing Wu, Xuan Li, Shu-Lei Liu, Jing-Ming Hou, Hong-Liang Liu, Jian-Feng Sui, Guang-Yan W. Reevaluating the ability of cerebellum in associative motor learning. Scientific reports. vol 9. issue 1. 2020-10-07. PMID:30988338. |
here, we used direct optogenetic stimulation of mossy fibers in the middle cerebellar peduncle (mcp) as a conditioned stimulus (cs) replacement for the peripheral cs (eg, a tone cs or a light cs) paired with a periorbital shock unconditioned stimulus (us) to examine the ability of the cerebellum to learn the dec and the tec with various trace intervals. |
2020-10-07 |
2023-08-13 |
rat |
| Da-Bing Li, Juan Yao, Lin Sun, Bing Wu, Xuan Li, Shu-Lei Liu, Jing-Ming Hou, Hong-Liang Liu, Jian-Feng Sui, Guang-Yan W. Reevaluating the ability of cerebellum in associative motor learning. Scientific reports. vol 9. issue 1. 2020-10-07. PMID:30988338. |
we show that all rats quickly acquired the dec, indicating that direct optogenetic stimulation of mossy fibers in the left mcp is a very effective and sufficient cs to establish dec and to limit the motor learning process inside the cerebellum. |
2020-10-07 |
2023-08-13 |
rat |
| Da-Bing Li, Juan Yao, Lin Sun, Bing Wu, Xuan Li, Shu-Lei Liu, Jing-Ming Hou, Hong-Liang Liu, Jian-Feng Sui, Guang-Yan W. Reevaluating the ability of cerebellum in associative motor learning. Scientific reports. vol 9. issue 1. 2020-10-07. PMID:30988338. |
moreover, pharmacological blocking glutamatergic and gabaergic inputs to the pn from the extra-cerebellar and cerebellar regions has no significant effect on the dec and tec learning with the optogenetic cs. |
2020-10-07 |
2023-08-13 |
rat |
| b' Lara Jehi, Nathalie Jett\\xc3\\xa. Not all that glitters is gold: A guide to surgical trials in epilepsy. Epilepsia open. vol 1. issue 1-2. 2020-09-30. PMID:29588926.' |
abstracts were screened to identify resective, palliative (e.g., corpus callosotomy, multiple subpial transection [mst]), ablative (e.g., laser interstitial thermal therapy [litt], gamma knife radiosurgery [rs]), and neuromodulation (e.g., cerebellar stimulation [cs], hippocampal stimulation [hs], repetitive transcranial magnetic stimulation [rtms], responsive neurostimulation [rns], thalamic stimulation [ts], trigeminal nerve stimulation [tns], and vagal nerve stimulation [vns]) rcts. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mallory Kerner-Rossi, Maria Gulinello, Steven Walkley, Kostantin Dobreni. Pathobiology of Christianson syndrome: Linking disrupted endosomal-lysosomal function with intellectual disability and sensory impairments. Neurobiology of learning and memory. vol 165. 2020-07-30. PMID:29772390. |
christianson syndrome (cs) is a recently described rare neurogenetic disorder presenting early in life with a broad range of neurological symptoms, including severe intellectual disability with nonverbal status, hyperactivity, epilepsy, and progressive ataxia due to cerebellar atrophy. |
2020-07-30 |
2023-08-13 |
mouse |
| Tadashi Shiohama, Jeremy McDavid, Jacob Levman, Emi Takahash. Quantitative brain morphological analysis in CHARGE syndrome. NeuroImage. Clinical. vol 23. 2020-06-29. PMID:31154243. |
while several neuroimaging studies have revealed abnormalities such as hypoplasia of the semicircular canal, olfactory nerve, cerebellum, and brainstem, no quantitative analysis of brain morphology in cs has been reported. |
2020-06-29 |
2023-08-13 |
human |
| Tianyu Tang, Timothy A Blenkinsop, Eric J Lan. Complex spike synchrony dependent modulation of rat deep cerebellar nuclear activity. eLife. vol 8. 2020-05-18. PMID:30624204. |
the results suggest that cs synchrony is a key control parameter of cerebellar output. |
2020-05-18 |
2023-08-13 |
rat |
| Thomas Michael Ernst, Anna Evelina Brol, Marcel Gratz, Christoph Ritter, Ulrike Bingel, Marc Schlamann, Stefan Maderwald, Harald H Quick, Christian Josef Merz, Dagmar Timman. The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm. eLife. vol 8. 2020-02-07. PMID:31464686. |
an event-related design allowed us to separate cerebellar fmri signals related to the visual conditioned stimulus (cs) from signals related to the subsequent unconditioned stimulus (us; an aversive electric shock). |
2020-02-07 |
2023-08-13 |
human |
| Lauren B Burhans, Bernard G Schreur. Inactivation of the interpositus nucleus during unpaired extinction does not prevent extinction of conditioned eyeblink responses or conditioning-specific reflex modification. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869952. |
because the shape and timing of crm closely resembles the conditioned eyeblink response (cr) to the tone conditioned stimulus (cs), we previously tested whether crs and crm share a common neural substrate, the interpositus nucleus of the cerebellum (ip), and found that ip inactivation during conditioning blocked the development of both crs and the timing aspect of crm. |
2020-01-09 |
2023-08-13 |
rabbit |
| A Namm, A Arend, M Aunapu. Expression of Pax2 protein during the formation of the central nervous system in human embryos. Folia morphologica. vol 73. issue 3. 2019-11-20. PMID:25346342. |
at later stages (cs 16-20) pax2 expression was observed in the midbrain-hindbrain boundary and also in the developing diencephalon and cerebellum. |
2019-11-20 |
2023-08-13 |
human |
| Sean J Farley, Heba Albazboz, Benjamin J De Corte, Jason J Radley, John H Freema. Amygdala central nucleus modulation of cerebellar learning with a visual conditioned stimulus. Neurobiology of learning and memory. vol 150. 2019-09-16. PMID:29535041. |
however, given that the cea projects to the medial auditory thalamus, a critical part of the auditory cs pathway in ebc, the cea influence on cerebellar learning could be specific to auditory stimuli. |
2019-09-16 |
2023-08-13 |
rat |
| Lang-Qian Zhang, Juan Yao, Jie Gao, Lin Sun, Li-Ting Wang, Jian-Feng Su. Modulation of eyeblink conditioning through sensory processing of conditioned stimulus by cortical and subcortical regions. Behavioural brain research. vol 359. 2019-04-03. PMID:30385367. |
using delay ebc (debc), a standard paradigm in which the unconditioned stimulus (us) is delayed and co-terminates with the conditioned stimulus (cs), converging lines of evidence has been accumulated and shows that the essential neural circuit mediating ebc resides in the cerebellum and brainstem. |
2019-04-03 |
2023-08-13 |
Not clear |
| Nian Wang, Robert J Anderson, Alexandra Badea, Gary Cofer, Russell Dibb, Yi Qi, G Allan Johnso. Whole mouse brain structural connectomics using magnetic resonance histology. Brain structure & function. vol 223. issue 9. 2019-03-08. PMID:30225830. |
compared to the fully sampled results at the same scan time, the subtle anatomical details of the brain, such as cortical layers, dentate gyrus, and cerebellum, were better visualized using cs due to the higher spatial resolution. |
2019-03-08 |
2023-08-13 |
mouse |
| Lara Fernandez, Brendan P Major, Wei-Peng Teo, Linda K Byrne, Peter G Enticot. The Impact of Stimulation Intensity and Coil Type on Reliability and Tolerability of Cerebellar Brain Inhibition (CBI) via Dual-Coil TMS. Cerebellum (London, England). vol 17. issue 5. 2018-11-06. PMID:29730789. |
cbi can be indexed via a dual-coil transcranial magnetic stimulation protocol, whereby a conditioning stimulus (cs) is delivered to the cerebellum in advance of a test stimulus (ts) to m1. |
2018-11-06 |
2023-08-13 |
human |