| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiunn-Min Shieh, Yih-Jeng Tsai, Ming-Chieh Ma, Chih-Li Chen, Wen-Bin W. The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555391. |
the cox-2 protein and mrna expression was found higher in nps than that in the control and crssnp patients' nasal tissues, mainly located at the epithelium and subepithelial stroma. |
2024-03-30 |
2024-04-02 |
human |
| Bernat Martí-García, Simon L Priestnall, Emma Holmes, Alejandro Suárez-Bonne. Olfactory neuroblastoma in a domestic cat and review of the literature. Veterinary clinical pathology. 2023-07-19. PMID:37468966. |
interestingly, and similar to nasal carcinomas, neoplastic cells diffusely neo-expressed cox-2. |
2023-07-19 |
2023-08-14 |
cat |
| Dah-Renn Fu, Tsuyoshi Kadosaw. Comparison of epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) immunohistochemical expression and outcomes in canine nasal carcinomas treated with radiation therapy. The Journal of veterinary medical science. 2022-07-19. PMID:35851267. |
comparison of epidermal growth factor receptor (egfr) and cyclooxygenase-2 (cox-2) immunohistochemical expression and outcomes in canine nasal carcinomas treated with radiation therapy. |
2022-07-19 |
2023-08-14 |
human |
| Dah-Renn Fu, Tsuyoshi Kadosaw. Comparison of epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) immunohistochemical expression and outcomes in canine nasal carcinomas treated with radiation therapy. The Journal of veterinary medical science. 2022-07-19. PMID:35851267. |
the expression of epidermal growth factor receptor (egfr) and cyclooxygenase-2 (cox-2) has been reported in human nasopharyngeal and canine nasal carcinomas. |
2022-07-19 |
2023-08-14 |
human |
| Dah-Renn Fu, Tsuyoshi Kadosaw. Comparison of epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) immunohistochemical expression and outcomes in canine nasal carcinomas treated with radiation therapy. The Journal of veterinary medical science. 2022-07-19. PMID:35851267. |
the present study measured egfr and cox-2 expression and calculated correlations between these proteins and clinical variables and outcomes in dogs with nasal carcinoma treated with radiation therapy. |
2022-07-19 |
2023-08-14 |
human |
| Dah-Renn Fu, Tsuyoshi Kadosaw. Comparison of epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) immunohistochemical expression and outcomes in canine nasal carcinomas treated with radiation therapy. The Journal of veterinary medical science. 2022-07-19. PMID:35851267. |
before treatment, the immunohistochemistry of egfr and cox-2 was performed in 67 biopsied tissues from canine nasal carcinomas. |
2022-07-19 |
2023-08-14 |
human |
| L-F Wang, C-H Lee, S-S Liang, C-C Hung, Y-R Wu, C-Y Chien, C-H Lee, J Y-F Che. Mucin 5AC is significantly upregulated in exosomes from the nasal lavage fluid and may promote the expression of COX-2, VEGF and MMP-9: an implication in nasal polyp pathogenesis. Rhinology. vol 59. issue 3. 2021-06-08. PMID:34091656. |
mucin 5ac is significantly upregulated in exosomes from the nasal lavage fluid and may promote the expression of cox-2, vegf and mmp-9: an implication in nasal polyp pathogenesis. |
2021-06-08 |
2023-08-13 |
human |
| Min Young Seo, Ki Ryung Kim, Jung Joo Lee, Gwanghui Ryu, Seung Hoon Lee, Sang Duk Hong, Hun-Jong Dhong, Chung-Hwan Baek, Seung-Kyu Chung, Hyo Yeol Ki. Therapeutic effect of topical administration of red onion extract in a murine model of allergic rhinitis. Scientific reports. vol 9. issue 1. 2020-09-21. PMID:30814581. |
allergic symptom score, serum total and ova specific ige, cytokine levels of nasal mucosa (interleukin (il)-4, il-5, il-10, il-13, ifn-γ, tnf-α and cox-2) and eosinophilic infiltration were higher in allergic mouse group than negative control group. |
2020-09-21 |
2023-08-13 |
mouse |
| Y Huang, H Lou, C Wang, L Zhan. Impact of cigarette smoke and IL-17A activation on asthmatic patients with chronic rhinosinusitis Rhinology. vol 57. issue 1. 2019-07-12. PMID:30609423. |
ilc3 cells were associated with il-17a, il-22, ahr, and cox-2 mrna expression.conclusions: cigarette smoking was related to lesser improvement in asthma control after nasal surgery and to il-17a activation in the nasal tissues of patients with inflammatory airways. |
2019-07-12 |
2023-08-13 |
Not clear |
| Meng Fu, Shulian Fu, Saihong Ni, Liyuan Zou, Yumei Liu, Tie Hon. Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis. International immunopharmacology. vol 49. 2018-05-01. PMID:28558302. |
after administration of egcg, the number of sneezes and the occurrence of nasal rubbing were significantly decreased, the concentrations of immunoglobulin e (ige) and histamine were suppressed in ar mouse serum, the levels of interleukin (il)-1β, il-4, and il-6 were reduced in ar mice nasal lavage fluid (nlf), and the nasal mucosa mrna and protein expression of cyclooxygenase 2 (cox-2), il-1β, il-4, and il-6 were inhibited. |
2018-05-01 |
2023-08-13 |
mouse |
| Jarosław Miłoński, Hanna Zielińska-Bliźniewska, Karolina Przybyłowska, Piotr Pietkiewicz, Barbara Korzycka-Zaborowska, Ireneusz Majsterek, Jurek Olszewsk. Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 272. issue 12. 2016-06-15. PMID:25573836. |
significance of cyclooxygenase-2(cox-2), periostin (postn) and interleukin-4(il-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps. |
2016-06-15 |
2023-08-13 |
Not clear |
| Jarosław Miłoński, Hanna Zielińska-Bliźniewska, Karolina Przybyłowska, Piotr Pietkiewicz, Barbara Korzycka-Zaborowska, Ireneusz Majsterek, Jurek Olszewsk. Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 272. issue 12. 2016-06-15. PMID:25573836. |
the purpose of this paper was to evaluate the level of cyclooxygenase-2 (cox-2), periostin (postn) and interleukin-4(il-4) gene expression in patients with chronic rhinosinusitis with nasal polyps, without polyps and with a nasal septum deviation. |
2016-06-15 |
2023-08-13 |
Not clear |
| Jarosław Miłoński, Hanna Zielińska-Bliźniewska, Karolina Przybyłowska, Piotr Pietkiewicz, Barbara Korzycka-Zaborowska, Ireneusz Majsterek, Jurek Olszewsk. Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 272. issue 12. 2016-06-15. PMID:25573836. |
the studies revealed an increased level of postn, il-4 gene expression and a decreased level of cox-2 gene expression that may be associated with the development of chronic rhinosinusitis with nasal polyps. |
2016-06-15 |
2023-08-13 |
Not clear |
| Simona Cancedda, Silvia Sabattini, Giuliano Bettini, Vito F Leone, Paola Laganga, Federica Rossi, Rossella Terragni, Giacomo Gnudi, Massimo Vignol. Combination of radiation therapy and firocoxib for the treatment of canine nasal carcinoma. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. vol 56. issue 3. 2016-05-19. PMID:25703137. |
cyclooxygenase-isoform-2 (cox-2) is expressed in 71-95% of canine nasal carcinomas and has been implicated in tumor growth and angiogenesis. |
2016-05-19 |
2023-08-13 |
Not clear |
| Simona Cancedda, Silvia Sabattini, Giuliano Bettini, Vito F Leone, Paola Laganga, Federica Rossi, Rossella Terragni, Giacomo Gnudi, Massimo Vignol. Combination of radiation therapy and firocoxib for the treatment of canine nasal carcinoma. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. vol 56. issue 3. 2016-05-19. PMID:25703137. |
dogs with histologically confirmed, previously untreated nasal carcinomas were randomized to receive the combination of a selective cox-2 inhibitor (firocoxib) and palliative rt (group 1) or rt and placebo (group 2). |
2016-05-19 |
2023-08-13 |
Not clear |
| Ling-Feng Wang, Chen-Yu Chien, Yi-Hsin Yang, Tzyh-Chyuan Hour, Sheau-Fang Yang, Hau-Ren Chen, Ke-Li Tsai, Jenq-Yuh Ko, Jeff Yi-Fu Che. Autophagy is deficient and inversely correlated with COX-2 expression in nasal polyps: a novel insight into the inflammation mechanism. Rhinology. vol 53. issue 3. 2015-11-16. PMID:26363168. |
autophagy is deficient and inversely correlated with cox-2 expression in nasal polyps: a novel insight into the inflammation mechanism. |
2015-11-16 |
2023-08-13 |
Not clear |
| Tae Young Jang, Chang-Shin Park, Kyu-Sung Kim, Min-Jeong Heo, Young Hyo Ki. Benzaldehyde suppresses murine allergic asthma and rhinitis. International immunopharmacology. vol 22. issue 2. 2015-06-09. PMID:25107441. |
the number of nose-scratching events in 10 min, levels of total and ovalbumin-specific ige in serum, differential counts of inflammatory cells in bronchoalveolar lavage (bal) fluid, titers of th2 cytokines (il-4, il-5, il-13) in bal fluid, histopathologic findings of lung and nasal tissues, and expressions of proteins involved in apoptosis (bcl-2, bax, caspase-3), inflammation (cox-2), antioxidation (extracellular sod, ho-1), and hypoxia (hif-1α, vegf) in lung tissue were evaluated. |
2015-06-09 |
2023-08-13 |
mouse |
| Xianying Meng, Xu Wu, Yibing Yua. [Significances of COX-2, p21, Ki-67 expression and HPV infection in nasal inverted papilloma]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 28. issue 23. 2015-05-30. PMID:25980147. |
[significances of cox-2, p21, ki-67 expression and hpv infection in nasal inverted papilloma]. |
2015-05-30 |
2023-08-13 |
Not clear |
| Xianying Meng, Xu Wu, Yibing Yua. [Significances of COX-2, p21, Ki-67 expression and HPV infection in nasal inverted papilloma]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 28. issue 23. 2015-05-30. PMID:25980147. |
to investigate the significance of expression of cox-2, p21, ki67 and hpv in nasal inverted papilloma. |
2015-05-30 |
2023-08-13 |
Not clear |
| Huajing Li, Zhigui Shan, Bowei Wang, Lizhong Li. [Expressions of EOS and COX-2 in nasal polyps in patients with aspirin triad syndrome and its significance]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 26. issue 11. 2015-05-16. PMID:22934333. |
[expressions of eos and cox-2 in nasal polyps in patients with aspirin triad syndrome and its significance]. |
2015-05-16 |
2023-08-12 |
Not clear |