| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Lesner, G Kupryszewski, K Rolk. Chromogenic substrates of bovine beta-trypsin: the influence of an amino acid residue in P1 position on their interaction with the enzyme. Biochemical and biophysical research communications. vol 285. issue 5. 2001-09-13. PMID:11478806. |
the cucurbita maxima trypsin inhibitor cmti-iii molecule was used as a vehicle to design and synthesize a series of trypsin chromogenic substrates modified in position p1: ac-ala-val-abu-pro-x-pna, where x = orn, lys, arg, har, arg(no(2)), cit, hci, phe(p-cn), phe(p-nh(2)); pna = p-nitroanilide. |
2001-09-13 |
2023-08-12 |
cat |
| N Sakura, K Kurosawa, T Hashimot. Structure-activity relationships of neuromedin U. IV. Absolute requirement of the arginine residue at position 7 of dog neuromedin U-8 for contractile activity. Chemical & pharmaceutical bulletin. vol 48. issue 8. 2000-12-28. PMID:10959581. |
to examine the role of both arg residues at positions 5 and 7 of dog neuromedin u-8 (d-nmu-8; pglu1-phe-leu-phe-arg5-pro-arg7-asn8-nh2) for smooth muscle contractile activity on isolated chicken crop, d-nmu-8 analogs were synthesized where either arg residue was systematically replaced by various amino acids [x: ala, thr, glu, gln, lys, orn, his, citrulline (cit) or homoarginine (har)]. |
2000-12-28 |
2023-08-12 |
dog |
| T R Mackle, D A Dwyer, K L Ingvartsen, P Y Chouinard, D A Ross, D E Bauma. Evaluation of whole blood and plasma in the interorgan supply of free amino acids for the mammary gland of lactating dairy cows. Journal of dairy science. vol 83. issue 6. 2000-11-14. PMID:10877395. |
concentrations of aa in red blood cells were either higher (asn+asp, gly, his, leu, met, orn, ser, tau, thr, and tyr), lower (ala, arg, cit, cys, ile, and val), or similar (gln+glu, phe, and pro) to that of plasma. |
2000-11-14 |
2023-08-12 |
Not clear |
| M X Li, T Nakajima, T Fukushige, K Kobayashi, N Seiler, T Sahek. Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator. Biochimica et biophysica acta. vol 1455. issue 1. 1999-10-22. PMID:10524224. |
ammonium chloride injection caused an increase in ornithine (orn) 5 min after injection and an increase in the sum of orn, citrulline (cit) and arginine (arg) for at least 15 min in the liver of control mice, but no increase in orn, cit and arg in the liver of spf-ash mice. |
1999-10-22 |
2023-08-12 |
mouse |
| M X Li, T Nakajima, T Fukushige, K Kobayashi, N Seiler, T Sahek. Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator. Biochimica et biophysica acta. vol 1455. issue 1. 1999-10-22. PMID:10524224. |
similar effects were observed with cit and orn at the same dose, and a long-lasting effect with an ornithine aminotransferase inactivator, 5-(fluoromethyl)ornithine, at a much lower dose. |
1999-10-22 |
2023-08-12 |
mouse |
| S Masumi, M Moriyama, Y Kannan, M Ohta, O Koshitani, O Sawamoto, S Toyoshima, K Ishikawa, M Miyoshi, T Sugan. Characteristics of nitrogen metabolism in rats with thioacetamide-induced liver cirrhosis. Toxicology. vol 132. issue 2-3. 1999-08-19. PMID:10433379. |
in the malnourished precirrhotic stage (stage 1) and the malnourished cirrhotic stage (stage 2), the aromatic amino acids (aaa), glu, asp, orn, arg and cit increased, and the branched-chain amino acids (bcaa) decreased slightly. |
1999-08-19 |
2023-08-12 |
human |
| S Masumi, M Moriyama, Y Kannan, M Ohta, O Koshitani, O Sawamoto, S Toyoshima, K Ishikawa, M Miyoshi, T Sugan. Characteristics of nitrogen metabolism in rats with thioacetamide-induced liver cirrhosis. Toxicology. vol 132. issue 2-3. 1999-08-19. PMID:10433379. |
the increases in glu, asp, orn and cit might have resulted from overproduction in the liver, because these contents of the liver increased in stage 2. |
1999-08-19 |
2023-08-12 |
human |
| A Bernhardt, M Drewello, M Schutkowsk. The solid-phase synthesis of side-chain-phosphorylated peptide-4-nitroanilides. The journal of peptide research : official journal of the American Peptide Society. vol 50. issue 2. 1997-10-02. PMID:9273898. |
preformed building blocks fmoc-xaa-nh-np (xaa = cit, cys, gln, his, lys, orn, ser, thr, tyr, trp) can be attached via side chain to the 2-chlorotritylchloride linker of the resin. |
1997-10-02 |
2023-08-12 |
Not clear |
| A Bernhardt, M Drewello, M Schutkowsk. The solid-phase synthesis of side-chain-phosphorylated peptide-4-nitroanilides. The journal of peptide research : official journal of the American Peptide Society. vol 50. issue 2. 1997-10-02. PMID:9273898. |
we synthesised a set of tetrapeptide-4-nitroanilides with the general structure suc-ala-phe-pro-xaa-nh-np (xaa = asp, cit, cys, glu, gln, his, lys, orn, ser, thr, tyr, trp). |
1997-10-02 |
2023-08-12 |
Not clear |
| M S Piepenbrink, T R Overton, J H Clar. Response of cows fed a low crude protein diet to ruminally protected methionine and lysine. Journal of dairy science. vol 79. issue 9. 1997-02-13. PMID:8899531. |
the dmi; yields of milk, 3.5% fcm, total n, protein n, and whey n; plasma concentrations of arg, cit, his, ile, leu, orn, phe, pro, tyr, val, and urea n were greater for cows fed the 18% cp diet. |
1997-02-13 |
2023-08-12 |
Not clear |
| L Castillo, M Sánchez, J Vogt, T E Chapman, T C DeRojas-Walker, S R Tannenbaum, A M Ajami, V R Youn. Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis. The American journal of physiology. vol 268. issue 2 Pt 1. 1995-03-21. PMID:7864114. |
the plasma fluxes of ornithine (orn), arginine (arg), and citrulline (cit) and rate of conversion of labeled ornithine-to-citrulline (qorn-->cit) were estimated in six healthy adult men receiving an arginine-rich or arginine-free l-amino acid-based diet, each for 6 days. |
1995-03-21 |
2023-08-12 |
human |
| J Guinard, H Rulqui. Effect of graded levels of duodenal infusions of casein on mammary uptake in lactating cows. 2. Individual amino acids. Journal of dairy science. vol 77. issue 11. 1995-02-09. PMID:7814706. |
infusions of casein linearly increased the arterial concentrations of all essential aa and several nonessential aa (pro, tyr, orn, and cit) and increased, or tended to increase, linearly the mammary arteriovenous differences of all aa except glu and ala. absorption ability of the mammary gland was not reduced in vivo. |
1995-02-09 |
2023-08-12 |
Not clear |
| b' H N\\xc3\\xa1dvorn\\xc3\\xadkov\\xc3\\xa1, O Sch\\xc3\\xbcck, V Teplan, J Kasl\\xc3\\xadkov\\xc3\\xa1, D Tomkov\\xc3\\xa1, V Reitschl\\xc3\\xa4gerov\\xc3\\xa. [Renal excretion of amino acids in patients on a regular dialysis program]. Vnitrni lekarstvi. vol 40. issue 4. 1994-06-14. PMID:8184580.' |
the reduced tubular transport of some of the investigated amino acids (cys, lys, cit, met, asn+gln, orn, ile) was significantly related with the drop of tubular sodium transport. |
1994-06-14 |
2023-08-12 |
human |
| V Tõugu, H Meos, M Haga, A Aaviksaar, H D Jakubk. Peptide synthesis by chymotrypsin in frozen solutions. Free amino acids as nucleophiles. FEBS letters. vol 329. issue 1-2. 1993-09-21. PMID:8354404. |
the efficiency of amino acids in the formation of the corresponding dipeptides depended on the substrate used, and decreased in the order ser,thr,gln > lys > cit > ala > ala > gly > asn > arg > glu > val > orn > asp with no peptide formed with his, leu, ile and pro) for n-maleyl-l-tyrosine ethyl ester and ser > lys > orn > arg,cit > gln > thr > asn > ala > gly (with no peptide formed with glu, val, asp, his, leu, ile and pro) for l-tyrosine ethyl ester. |
1993-09-21 |
2023-08-12 |
Not clear |
| M D Hanigan, C C Calvert, E J DePeters, B L Reis, R L Baldwi. Kinetics of amino acid extraction by lactating mammary glands in control and sometribove-treated Holstein cows. Journal of dairy science. vol 75. issue 1. 1992-04-08. PMID:1541729. |
extractions of asn, his, thr, arg, tyr, met, cystathionine, cystine, ile, phe, orn, glu, gly, tau, cit, leu, and val were correlated linearly with arterial concentrations (r2 greater than .15) of each aa. |
1992-04-08 |
2023-08-11 |
Not clear |
| M D Hanigan, C C Calvert, E J DePeters, B L Reis, R L Baldwi. Kinetics of amino acid extraction by lactating mammary glands in control and sometribove-treated Holstein cows. Journal of dairy science. vol 75. issue 1. 1992-04-08. PMID:1541729. |
extractions of asp, glu, ser, asn, gly, gln, tau, his, cit, thr, pro, tyr, val, cystine, ile, leu, trp, orn, and lys also were correlated with arteriovenous differences of met. |
1992-04-08 |
2023-08-11 |
Not clear |
| M Gekle, S Silbernag. Basolateral uptake and tubular metabolism of L-citrulline in the isolated-perfused non-filtering kidney of the African clawed toad (Xenopus laevis). Pflugers Archiv : European journal of physiology. vol 419. issue 5. 1992-03-05. PMID:1775371. |
and (c) is this cit, entering the cell from the peritubular side, metabolized to arg and ornithine (orn)? |
1992-03-05 |
2023-08-11 |
rat |
| M S Edmonds, K R Lowry, D H Bake. Urea cycle metabolism: effects of supplemental ornithine or citrulline on performance, tissue amino acid concentrations and enzymatic activity in young pigs fed arginine-deficient diets. Journal of animal science. vol 65. issue 3. 1987-12-14. PMID:3667436. |
two experiments were conducted with young pigs to determine the efficacy of ornithine (orn) or citrulline (cit) as precursors of arginine (arg). |
1987-12-14 |
2023-08-11 |
Not clear |
| M S Edmonds, K R Lowry, D H Bake. Urea cycle metabolism: effects of supplemental ornithine or citrulline on performance, tissue amino acid concentrations and enzymatic activity in young pigs fed arginine-deficient diets. Journal of animal science. vol 65. issue 3. 1987-12-14. PMID:3667436. |
1, pigs were individually fed an arg-deficient, semipurified diet (.18% arg) supplemented with .3% arg or an equimolar quantity of orn or cit. |
1987-12-14 |
2023-08-11 |
Not clear |
| M S Edmonds, K R Lowry, D H Bake. Urea cycle metabolism: effects of supplemental ornithine or citrulline on performance, tissue amino acid concentrations and enzymatic activity in young pigs fed arginine-deficient diets. Journal of animal science. vol 65. issue 3. 1987-12-14. PMID:3667436. |
supplemental arg or cit increased rate and efficiency of weight gain, but orn addition was without effect. |
1987-12-14 |
2023-08-11 |
Not clear |