Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Vladislav Volarevic, Marija Milovanovic, Biljana Ljujic, Nada Pejnovic, Nebojsa Arsenijevic, Ulf Nilsson, Hakon Leffler, Miodrag L Luki. Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice. Hepatology (Baltimore, Md.). vol 55. issue 6. 2012-08-02. PMID:22213244. |
the level of tumor necrosis factor alpha (tnfα), interferon gamma (ifnγ), and interleukin (il)-17 and -4 in the sera and the number of tnfα-, ifnγ-, and il-17- and -4-producing cluster of differentiation (cd)4(+) cells as well as il-12-producing cd11c(+) dcs were lower, whereas the number of il-10-producing cd4(+) t cells and f4/80(+) macrophages were significantly higher in livers of gal-3(-/-) mice. |
2012-08-02 |
2023-08-12 |
mouse |
Alvaro Darriba, Paula Pazo-Álvarez, Almudena Capilla, Elena Amened. Oscillatory brain activity in the time frequency domain associated to change blindness and change detection awareness. Journal of cognitive neuroscience. vol 24. issue 2. 2012-06-04. PMID:21671737. |
relative to no-change and cd, cb was associated with a pronounced theta power enhancement at parietal-occipital and occipital sites and broadly distributed alpha power suppression during the processing of the prechange display. |
2012-06-04 |
2023-08-12 |
Not clear |
Abhishek Basu, Rakesh Chatterjee, Saumen Datt. Expression, purification, structural and functional analysis of SycB: a type three secretion chaperone from Yersinia enterocolitica. The protein journal. vol 31. issue 1. 2012-04-12. PMID:22170450. |
far uv cd spectra confirm that sycb is predominantly alpha helical. |
2012-04-12 |
2023-08-12 |
Not clear |
A Tinsley, E A Macklin, J R Korzenik, B E Sand. Validation of the functional assessment of chronic illness therapy-fatigue (FACIT-F) in patients with inflammatory bowel disease. Alimentary pharmacology & therapeutics. vol 34. issue 11-12. 2012-03-16. PMID:21999576. |
internal consistency was measured by cronbach's alpha; test-retest reliability by the intraclass correlation coefficient (icc); validity by the correlation of the facit-f score with c-reactive protein (crp) erythrocyte sedimentation rate (esr), haematocrit (hct) and disease activity as measured by the harvey-bradshaw index (hbi; cd) and simple clinical colitis activity index (sccai; uc). |
2012-03-16 |
2023-08-12 |
Not clear |
Nuray Yazıhan, Mehtap Kaçar Koçak, Ethem Akçıl, Onur Erdem, Ahmet Sayal, Cengiz Güven, Nalan Akyüre. Involvement of galectin-3 in cadmium-induced cardiac toxicity. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology. vol 11. issue 6. 2012-01-25. PMID:21788204. |
the present study was focused to evaluate roles of tumor necrosis factor alpha (tnf-α) and interleukin-6 (il-6) in cd toxicity and their relationships with galectin-3 levels. |
2012-01-25 |
2023-08-12 |
Not clear |
Michael B Sprakes, P John Hamlin, Lisa Warren, Dan Greer, Alexander C For. Adalimumab as second line anti-tumour necrosis factor alpha therapy for Crohn's disease: A single centre experience. Journal of Crohn's & colitis. vol 5. issue 4. 2012-01-13. PMID:21683302. |
non-response, loss of response, or intolerance to anti-tumour necrosis factor alpha (anti-tnfα) therapy is well recognised in crohn's disease (cd) patients. |
2012-01-13 |
2023-08-12 |
Not clear |
Saleh A Naser, Claudia Romero, Princess Urbina, Najih Naser, John Valentin. Cellular infiltration and cytokine expression correlate with fistulizing state in Crohn's disease. Clinical and vaccine immunology : CVI. vol 18. issue 9. 2012-01-12. PMID:21752952. |
the purpose of this study was to determine the degree of infiltration of different cell subpopulations (tissue dendritic macrophages, t-helper cells, cytotoxic t lymphocytes, monocytes, neutrophils, and b cells) and the expression of the cytokines interleukin-12 (il-12) and tumor necrosis factor alpha (tnf-α) in inflamed and noninflamed resected tissues from crohn's disease (cd) and non-cd patients. |
2012-01-12 |
2023-08-12 |
human |
C Savoye-Collet, G Savoye, E Koning, J N Dacher, E Lerebour. Fistulizing perianal Crohn's disease: contrast-enhanced magnetic resonance imaging assessment at 1 year on maintenance anti-TNF-alpha therapy. Inflammatory bowel diseases. vol 17. issue 8. 2011-12-27. PMID:21744430. |
the aim of the study was to assess perianal fistulas by magnetic resonance imaging (mri) in patients with severe fistulizing crohn's disease (cd) using maintenance antitumor necrosis factor alpha (tnf-α) therapy and to correlate mri changes with clinical outcome. |
2011-12-27 |
2023-08-12 |
Not clear |
Stefan Schreibe. Certolizumab pegol for the treatment of Crohn's disease. Therapeutic advances in gastroenterology. vol 4. issue 6. 2011-11-10. PMID:22043230. |
in this article we provide a contemporary overview of available clinical data on certolizumab pegol, a pegylated anti-tumor necrosis factor (tnf) alpha agent that comprises a uniquely small protein, and its emerging role as a therapy for crohn's disease (cd). |
2011-11-10 |
2023-08-12 |
Not clear |
Kiera Murphy, Orla O'Sullivan, Mary C Rea, Paul D Cotter, R Paul Ross, Colin Hil. Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters. PloS one. vol 6. issue 7. 2011-10-13. PMID:21760885. |
indeed, thuricin cd and subtilosin a are the only antimicrobials known to possess these unusual structures and are known as the sactibiotics (sulplur to alpha carbon-containing antibiotics). |
2011-10-13 |
2023-08-12 |
Not clear |
W Reinisch, C Dejaco, T Feichtenschlager, T Haas, A Kaser, W Miehsler, G Novacek, W Petritsch, R Platzer, H Tilg, H Vogelsang, P Knoflac. [Infliximab therapy for Crohn's disease - a practical guideline: actualised consensus of the working group for chronic inflammatory bowel diseases of the Austrian Society for Gastroenterology and Hepatology]. Zeitschrift fur Gastroenterologie. vol 49. issue 4. 2011-09-02. PMID:21442574. |
infliximab is a monoclonal antibody against tumor necrosis factor alpha (tnf-α), which is approved for the treatment of chronic inflammatory bowel disease (ibd) such as crohn's disease (cd), fistulating crohn's disease (fcd), ulcerative colitis (uc), and paediatric ulcerative colitis (puc) from 6 years onwards. |
2011-09-02 |
2023-08-12 |
Not clear |
M J Stillman, A Presta, Z Gui, D T Jian. Spectroscopic studies of copper, silver and gold-metallothioneins. Metal-based drugs. vol 1. issue 5-6. 2011-07-14. PMID:18476257. |
(113)cd nmr spectroscopic and x-ray crystallographic data show that mammalian cd(7)-mt and zn(7)-mt have a two domain structure, with metal-thiolate clusters of the form m(4)(s(cys))(11) (the alpha domain) and m(3)(s(cys))(9) (the beta domain). |
2011-07-14 |
2023-08-12 |
rabbit |
Subrata Ghosh, Remo Panaccion. Anti-adhesion molecule therapy for inflammatory bowel disease. Therapeutic advances in gastroenterology. vol 3. issue 4. 2011-07-14. PMID:21180606. |
although biologic agents directed against tumor necrosis factor alpha (tnfα) continue to be an effective therapeutic strategy for patients with inflammatory bowel disease (ibd), approximately 30% of patients with crohn's disease (cd) who are refractory to standard treatment do not respond to induction therapy with tnfα inhibitors and, of those who initially respond, 50% or more cease to respond within a year. |
2011-07-14 |
2023-08-12 |
human |
Kalyan Ray Parashette, Raghavendra Charan Makam, Carmen Cuffar. Infliximab therapy in pediatric Crohn's disease: a review. Clinical and experimental gastroenterology. vol 3. 2011-07-14. PMID:21694847. |
anti-tumor necrosis factor alpha (tnf-α) therapy has re-defined our treatment paradigms in managing patients with crohn's disease (cd) and ulcerative colitis. |
2011-07-14 |
2023-08-12 |
Not clear |
Z Han, C Li, S Han, Y Han, J Qiu, Y Shi, J Wang, A Sun, J Ding, K Wu, D Fa. Meta-analysis: polymorphisms in TNF-alpha gene promoter and Crohn's disease. Alimentary pharmacology & therapeutics. vol 32. issue 2. 2011-06-17. PMID:20456305. |
tumour necrosis factor alpha (tnf-alpha) is involved in the pathogenesis of crohn's disease (cd). |
2011-06-17 |
2023-08-12 |
Not clear |
Yin Shi, En-Hua Zhou, Huan-Gan Wu, Ci-Li Zhou, Qian-Yao Wang, Li Q. Moxibustion treatment restoring the intestinal epithelium barrier in rats with Crohn's disease by down-regulating tumor necrosis factor alpha, tumor necrosis factor receptor 1, and tumor necrosis factor receptor 2. Chinese journal of integrative medicine. vol 17. issue 3. 2011-06-14. PMID:21359923. |
to investigate whether moxibustion regulates tumor necrosis factor alpha (tnf-α), tumor necrosis factor receptor 1 (tnfr1), and tnfr2 in the intestinal mucosa and to explore whether moxibustion could be used by means of this mechanism, to repair the intestinal epithelium barrier disruption in crohn's disease (cd). |
2011-06-14 |
2023-08-12 |
rat |
Raktim Mukherjee, Sudeep Banerjee, Niraj Joshi, Prem Kumar Singh, Darshee Baxi, A V Ramachandra. A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage. Cardiovascular toxicology. vol 11. issue 1. 2011-05-23. PMID:21046280. |
present study evaluates cardioprotective role of melatonin (mel), alpha lipoic acid (ala), a combination of melatonin and alpha lipoic acid (mel + ala) against cadmium (cd)-induced oxidative damage. |
2011-05-23 |
2023-08-12 |
rat |
Sa'ad Y Salim, Johan D Söderhol. Importance of disrupted intestinal barrier in inflammatory bowel diseases. Inflammatory bowel diseases. vol 17. issue 1. 2011-05-12. PMID:20725949. |
the main cytokine that seems to drive these changes is tumor necrosis factor alpha in cd, whereas interleukin (il)-13 may be more important in uc. |
2011-05-12 |
2023-08-12 |
human |
Christopher W am Ende, Hai Yun Meng, Mao Ye, Anil K Pandey, Neal J Zondl. Design of lanthanide fingers: compact lanthanide-binding metalloproteins. Chembiochem : a European journal of chemical biology. vol 11. issue 12. 2010-12-29. PMID:20623571. |
cd spectra of the peptide-lanthanide complexes are similar to those of zinc fingers and other beta beta alpha proteins. |
2010-12-29 |
2023-08-12 |
Not clear |
W Aaron Shoults-Wilson, Jason M Unrine, James Rickard, Marsha C Blac. Comparison of metal concentrations in Corbicula fluminea and Elliptio hopetonensis in the Altamaha River system, Georgia, USA. Environmental toxicology and chemistry. vol 29. issue 9. 2010-12-27. PMID:20821660. |
concentrations of as, cd, cu, hg, and pb were found to be significantly (alpha = 0.05) positively correlated between the two species. |
2010-12-27 |
2023-08-12 |
Not clear |