Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
N J Greenfield, S E Hitchcock-DeGregor. Conformational intermediates in the folding of a coiled-coil model peptide of the N-terminus of tropomyosin and alpha alpha-tropomyosin. Protein science : a publication of the Protein Society. vol 2. issue 8. 1993-10-28. PMID:8401212. |
when the cd spectrum of striated muscle alpha alpha-tropomyosin was examined as a function of temperature, the unfolding was also not totally cooperative. |
1993-10-28 |
2023-08-12 |
Not clear |
M Kotani, Y Yamamura, M Tsudo, T Tamatani, F Kitamura, M Miyasak. Generation of monoclonal antibodies to the rabbit interleukin-2 receptor alpha chain (CD25) and its distribution in HTLV-1-transformed rabbit T cells. Japanese journal of cancer research : Gann. vol 84. issue 7. 1993-10-08. PMID:8370651. |
together with mabs against various rabbit cd antigens that we reported previously, these neutralizing mabs to il-2r alpha will be valuable for studies of human retrovirus infections, such as those induced by htlv-1 or hiv, in rabbits. |
1993-10-08 |
2023-08-12 |
human |
M Yiangou, J Papaconstantino. The differential induction of alpha 1-acid glycoprotein and serum amyloid A genes by heavy metals. Biochimica et biophysica acta. vol 1174. issue 2. 1993-09-24. PMID:8357829. |
we have investigated the differential regulation of the mouse (balb/c) acute phase reactants, alpha 1-acid glycoprotein and serum amyloid a by heavy metals (hg, cd, pb, cu, ni and zn). |
1993-09-24 |
2023-08-12 |
mouse |
J Mo, M E Holtzer, A Holtze. Further characterization of the kinetic folding intermediate of alpha alpha-tropomyosin and of its 142-281 subsequence. Biopolymers. vol 33. issue 5. 1993-09-03. PMID:8343577. |
the backbone cd spectrum from 250 to 212 nm for the kinetic folding intermediate of alpha alpha-tropomyosin (alpha alpha-tm) and nonpolymerizable alpha alpha-tm was obtained. |
1993-09-03 |
2023-08-12 |
Not clear |
M Bourke, M O'Donovan, F M Stevens, C F McCarth. Alpha 1-antitrypsin phenotypes in coeliac patients and a control population in the west of Ireland. Irish journal of medical science. vol 162. issue 5. 1993-08-20. PMID:8335451. |
alpha 1 antitrypsin or protease inhibitor (pi) phenotyping was carried out on 111 coeliac disease patients (cd) and 250 controls. |
1993-08-20 |
2023-08-12 |
Not clear |
F Petronzelli, G Multari, P Ferrante, M Bonamico, G Rabuffo, L Campea, M C Mazzill. Different dose effect of HLA-DQ alpha beta heterodimers in insulin-dependent diabetes mellitus and celiac disease susceptibility. Human immunology. vol 36. issue 3. 1993-07-30. PMID:8320134. |
to compare the quantitative effect of the dq alpha beta heterodimers dq alpha 52 arg+, beta 57 asp- and dq alpha 1*0501, beta 1*0201 on susceptibility to iddm and cd, we characterized, at the genomic level, the dq alpha 52 and dq beta 57 residues of 50 iddm italian patients observed in rome. |
1993-07-30 |
2023-08-12 |
human |
F Petronzelli, G Multari, P Ferrante, M Bonamico, G Rabuffo, L Campea, M C Mazzill. Different dose effect of HLA-DQ alpha beta heterodimers in insulin-dependent diabetes mellitus and celiac disease susceptibility. Human immunology. vol 36. issue 3. 1993-07-30. PMID:8320134. |
in fact, the highest risk of iddm is for subjects alpha ss, beta ss that could express, by either cis- or trans-association, four susceptible heterodimers and decreases in proportion to the number of these; in regard to cd, the highest risk was found for individuals who carried only one predisposing heterodimer. |
1993-07-30 |
2023-08-12 |
human |
K E Lundin, H Scott, T Hansen, G Paulsen, T S Halstensen, O Fausa, E Thorsby, L M Solli. Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. The Journal of experimental medicine. vol 178. issue 1. 1993-07-23. PMID:8315377. |
the findings suggest preferential mucosal presentation of gluten-derived peptides by hla-dq(alpha 1*0501, beta 1*0201) in cd, which may explain the hla association. |
1993-07-23 |
2023-08-12 |
human |
C Astbury, R Platt, J S Dixon, P Le Gallez, J Hill, H A Bir. Optimizing the assessment of disease activity during treatment with anti-rheumatoid drugs. British journal of rheumatology. vol 32. issue 6. 1993-07-13. PMID:8099519. |
over a 48-week study period, changes in cytidine deaminase (cd), beta 2-microglobulin, alpha 1-acid glycoprotein (alpha 1-agp), serum antibodies to clostridium perfringens alpha-toxin, pre-albumin and caeruloplasmin were compared to a group of established clinical and laboratory assessments including plasma viscosity, crp haemoglobin and platelet count during treatment with the established second-line drugs, d-penicillamine (n = 20), sulphasalazine (n = 17), gold (n = 12) and hydroxychloroquine (n = 18). |
1993-07-13 |
2023-08-12 |
Not clear |
C Astbury, R Platt, J S Dixon, P Le Gallez, J Hill, H A Bir. Optimizing the assessment of disease activity during treatment with anti-rheumatoid drugs. British journal of rheumatology. vol 32. issue 6. 1993-07-13. PMID:8099519. |
overall, the assessments showing the greatest degree of change were plasma viscosity, articular index, summated change score, platelet count, cd, white cell count, alpha 1-agp, crp and pain score. |
1993-07-13 |
2023-08-12 |
Not clear |
K Park, A Perczel, G D Fasma. Differentiation between transmembrane helices and peripheral helices by the deconvolution of circular dichroism spectra of membrane proteins. Protein science : a publication of the Protein Society. vol 1. issue 8. 1993-07-08. PMID:1338977. |
the deconvoluted cd spectrum for the alpha t helix was characterized by a positive red-shifted band in the range 195-200 nm (+95,000 deg cm2 dmol-1), with the intensity of the negative band at 208 nm being slightly less negative than that of the 222-nm band (-50,000 and -60,000 deg cm2 dmol-1, respectively) in comparison with the regular alpha helix, with a positive band at 190 nm and two negative bands at 208 and 222 nm with magnitudes of +70,000, -30,000, and -30,000 deg cm2 dmol-1, respectively. |
1993-07-08 |
2023-08-11 |
Not clear |
J Rizo, F J Blanco, B Kobe, M D Bruch, L M Gierasc. Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments. Biochemistry. vol 32. issue 18. 1993-06-11. PMID:8387821. |
all these comparisons were facilitated by the use of upfield shifts of h alpha protons in helical regions relative to random coil chemical shifts, which also yielded estimates of helical content that correlated well with the cd results. |
1993-06-11 |
2023-08-12 |
Not clear |
E Gazit, Y Sha. Structural and functional characterization of the alpha 5 segment of Bacillus thuringiensis delta-endotoxin. Biochemistry. vol 32. issue 13. 1993-05-05. PMID:8384882. |
the alpha-helical content of the peptides, assessed in methanol by circular dichroism (cd), was 58% and 24% for alpha 5 and p-alpha 5, respectively. |
1993-05-05 |
2023-08-12 |
human |
b' Y Blancuzzi, A Padilla, J Parello, A Cav\\xc3\\xa. Symmetrical rearrangement of the cation-binding sites of parvalbumin upon Ca2+/Mg2+ exchange. A study by 1H 2D NMR. Biochemistry. vol 32. issue 5. 1993-04-13. PMID:8095405.' |
similarly, chemical shift effects, which selectively involve nh and c alpha h resonances (as well as side-chain resonances) in both cd and ef sites, point to a symmetrical behavior of both cation-binding sites upon ca2+/mg2+ exchange. |
1993-04-13 |
2023-08-12 |
Not clear |
A Pastore, R De Francesco, M A Castiglione Morelli, D Nalis, R Cortes. The dimerization domain of LFB1/HNF1 related transcription factors: a hidden four helix bundle? Protein engineering. vol 5. issue 8. 1993-03-16. PMID:1337605. |
in previous papers we have described the conformational stability as determined by cd and the secondary structure by nmr studies of a peptide with the amino acid sequence of the dimerization domain of lfb1/hnf1 alpha. |
1993-03-16 |
2023-08-11 |
Not clear |
B Malavasi, M F Rasetti, P Roma, R Fogliatto, P Allevi, A L Catapano, G Gall. Evidence for the presence of 7-hydroperoxycholest-5-en-3 beta-ol in oxidized human LDL. Chemistry and physics of lipids. vol 62. issue 3. 1993-01-28. PMID:1468120. |
the concentration of 7-hydroperoxycholest-5-en-3 beta-ol decreased with oxidation time with a concomitant increase of cholest-5-en-3 beta, 7 alpha-diol (7 alpha oh), cholest-5-en-3 beta, 7 beta-diol (7 beta oh), cholesta-3,5-dien-7-one (cd) and cholest-5-en-3 beta-ol-7-one (7co). |
1993-01-28 |
2023-08-11 |
human |
K Hundegger, M Stufler, U Karbac. Enteric protein loss as a marker of intestinal inflammatory activity in Crohn's disease: comparability of enteric clearance and stool concentration of alpha-1-antitrypsin? Zeitschrift fur Gastroenterologie. vol 30. issue 10. 1992-12-21. PMID:1441675. |
intestinal alpha 1-antitrypsin (alpha 1-at) clearance has been shown a reliable index of intestinal inflammatory activity in crohn's disease (cd). |
1992-12-21 |
2023-08-11 |
Not clear |
K Hundegger, M Stufler, U Karbac. Enteric protein loss as a marker of intestinal inflammatory activity in Crohn's disease: comparability of enteric clearance and stool concentration of alpha-1-antitrypsin? Zeitschrift fur Gastroenterologie. vol 30. issue 10. 1992-12-21. PMID:1441675. |
in 60 controls and in 70 patients with cd, in 21 patients before and after treatment, fecal alpha 1-at concentration and the ratio of stool and serum alpha 1-at concentration were compared with alpha 1-at clearance. |
1992-12-21 |
2023-08-11 |
Not clear |
K Hundegger, M Stufler, U Karbac. Enteric protein loss as a marker of intestinal inflammatory activity in Crohn's disease: comparability of enteric clearance and stool concentration of alpha-1-antitrypsin? Zeitschrift fur Gastroenterologie. vol 30. issue 10. 1992-12-21. PMID:1441675. |
alpha 1-at clearance (104 +/- 14 vs. 17.5 +/- 2 ml/d, p < 0.0001) as well as fecal alpha 1-at concentration (155 +/- 21 vs. 30 +/- 3 mg/100 ml, p < 0.0001) and stool/serum alpha 1-at concentration ratio (45 +/- 6 vs. 12 +/- 1) were significantly higher in cd patients than in controls. |
1992-12-21 |
2023-08-11 |
Not clear |
T Loftsson, J Baldvinsdótti. Degradation of tauromustine (TCNU) in aqueous solutions. Acta pharmaceutica Nordica. vol 4. issue 3. 1992-12-18. PMID:1418640. |
hydroxypropyl-alpha-cyclodextrin (hp alpha cd) had the largest stabilizing effect. |
1992-12-18 |
2023-08-11 |
Not clear |