| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kantorow, J Horwitz, M A van Boekel, W W de Jong, J Piatigorsk. Conversion from oligomers to tetramers enhances autophosphorylation by lens alpha A-crystallin. Specificity between alpha A- and alpha B-crystallin subunits. The Journal of biological chemistry. vol 270. issue 29. 1995-08-22. PMID:7615520. |
circular dichroism (cd) spectra of alpha-crystallin revealed little or no change in secondary and tertiary structures in 1% deoxycholate, alpha a2d, a truncated form of bovine alpha a that exists as a tetramer, was as active for autophosphorylation in the absence of deoxycholate as intact alpha a was in the presence of deoxycholate. |
1995-08-22 |
2023-08-12 |
chicken |
| X R Yao, H Flaswinkel, M Reth, D W Scot. Immunoreceptor tyrosine-based activation motif is required to signal pathways of receptor-mediated growth arrest and apoptosis in murine B lymphoma cells. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 2. 1995-08-16. PMID:7608543. |
here, we demonstrate that cross-linking of cd8:ig alpha or cd:ig beta with anti-cd8 mab effectively induced cell growth arrest and apoptosis characterized by [3h]thymidine release and dna fragmentation; in contrast, cd8:gamma 2a or truncated cd8:ig alpha lacking the itam could not do so. |
1995-08-16 |
2023-08-12 |
Not clear |
| G Paulsen, K E Lundin, H A Gjertsen, T Hansen, L M Sollid, E Thorsb. HLA-DQ2-restricted T-cell recognition of gluten-derived peptides in celiac disease. Influence of amino acid substitutions in the membrane distal domain of DQ beta 1*0201. Human immunology. vol 42. issue 2. 1995-06-15. PMID:7744618. |
we have recently shown that gluten-specific cd4+ t cells from the small intestinal mucosa of cd patients are predominantly restricted by the cd-associated hla-dq(alpha 1*0501, beta 1*0201) heterodimer. |
1995-06-15 |
2023-08-12 |
Not clear |
| J A Hubbard, L K MacLachlan, E Meenan, C J Salter, D G Reid, P Lahouratate, J Humphries, N Stevens, D Bell, W A Nevill. Conformation of the cytoplasmic domain of phospholamban by NMR and CD. Molecular membrane biology. vol 11. issue 4. 1995-05-16. PMID:7711836. |
evidence for this is provided by alpha ch chemical shifts and low nh chemical shift temperature coefficients, small nh-alpha ch intraresidue scalar coupling constants, a substantial number of distinctive interresidue nuclear overhauser effects (noes) [dnn(i, i + 1), d alpha n(i, i + 3), d alpha beta(i, i + 3) and d alpha n(i, i + 4)] and characteristic cd bands at 190 (positive), 206 (negative) and 222 nm (negative). |
1995-05-16 |
2023-08-12 |
Not clear |
| X Xu, L G Cooper, P J DiMario, J W Nelso. Helix formation in model peptides based on nucleolin TPAKK motifs. Biopolymers. vol 35. issue 1. 1995-05-04. PMID:7696559. |
when trifluoroethanol (tfe) is added, more extensive structural changes are observed, resembling helical structure based on nmr nuclear overhauser effect (noe) and c alpha proton chemical shift changes, and cd spectra. |
1995-05-04 |
2023-08-12 |
Not clear |
| O Saitoh, H Matsumoto, K Sugimori, K Sugi, K Nakagawa, H Miyoshi, I Hirata, R Matsuse, K Uchida, S Ohshib. Intestinal protein loss and bleeding assessed by fecal hemoglobin, transferrin, albumin, and alpha-1-antitrypsin levels in patients with colorectal diseases. Digestion. vol 56. issue 1. 1995-04-27. PMID:7895935. |
levels of all 4 proteins were significantly increased in patients with colonic cancer and ulcerative colitis (uc) compared to levels in control subjects, while fecal alpha 1-antitrypsin was particularly elevated in colonic crohn's disease (cd). |
1995-04-27 |
2023-08-12 |
human |
| O Saitoh, H Matsumoto, K Sugimori, K Sugi, K Nakagawa, H Miyoshi, I Hirata, R Matsuse, K Uchida, S Ohshib. Intestinal protein loss and bleeding assessed by fecal hemoglobin, transferrin, albumin, and alpha-1-antitrypsin levels in patients with colorectal diseases. Digestion. vol 56. issue 1. 1995-04-27. PMID:7895935. |
in cd, however, the difference in alpha 1-antitrypsin concentration was significant. |
1995-04-27 |
2023-08-12 |
human |
| K E Lundin, H Scott, O Fausa, E Thorsby, L M Solli. T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. Human immunology. vol 41. issue 4. 1995-04-12. PMID:7883596. |
however, a small percentage of cd patients do not carry this dq heterodimer, and most of them instead carry dq (alpha 1*0301, beta 1*0302) (dq8). |
1995-04-12 |
2023-08-12 |
Not clear |
| J J Piscatelli, S A Cohen, C S Berenson, P Lanc. Determinants of differential liver-colonizing potential of variants of the MCA-38 murine colon cancer cell line. Clinical & experimental metastasis. vol 13. issue 2. 1995-04-07. PMID:7882616. |
differing patterns of membrane sialylation may have contributed to the contrasting hepatic tumorigenicities of ld and cd cells; beta-galactoside alpha 2,6-sialyltransferase mrna levels and activity were approximately four-fold higher in ld than cd cells and qualitative and quantitative differences existed between their ganglioside profiles. |
1995-04-07 |
2023-08-12 |
mouse |
| I Kirman, O H Nielsen, E Kjaersgaard, J Brynsko. Interleukin-2 receptor alpha and beta chain expression by circulating alpha beta and gamma delta T cells in inflammatory bowel disease. Digestive diseases and sciences. vol 40. issue 2. 1995-03-16. PMID:7851192. |
to elucidate this, interleukin-2 receptor (il-2r) alpha and il-2r beta single chain expression and coexpression by peripheral blood tcr alpha beta + cells and tcr gamma delta + cells was studied in 21 patients with ulcerative colitis (uc), 25 with crohn's disease (cd), and 15 controls. |
1995-03-16 |
2023-08-12 |
Not clear |
| I Kirman, O H Nielsen, E Kjaersgaard, J Brynsko. Interleukin-2 receptor alpha and beta chain expression by circulating alpha beta and gamma delta T cells in inflammatory bowel disease. Digestive diseases and sciences. vol 40. issue 2. 1995-03-16. PMID:7851192. |
in contrast, the percentages of il-2r alpha-beta + and il-2r alpha + beta + tcr gamma delta + cells were increased in patients with inactive uc (p < 0.01), but not in cd. |
1995-03-16 |
2023-08-12 |
Not clear |
| E Gazit, Y Sha. The assembly and organization of the alpha 5 and alpha 7 helices from the pore-forming domain of Bacillus thuringiensis delta-endotoxin. Relevance to a functional model. The Journal of biological chemistry. vol 270. issue 6. 1995-03-16. PMID:7852320. |
circular dichroism (cd) spectroscopy revealed that alpha 7 adopts a predominantly alpha-helical structure in methanol, similar to what has been found for alpha 5, and consistent with its structure in the intact molecule. |
1995-03-16 |
2023-08-12 |
Not clear |
| S Simsek, P Noris, M Lozano, M Pico, A E von dem Borne, A Ribera, D Gallard. Cys209 Ser mutation in the platelet membrane glycoprotein Ib alpha gene is associated with Bernard-Soulier syndrome. British journal of haematology. vol 88. issue 4. 1995-02-14. PMID:7819107. |
previous studies with monoclonal antibodies directed against gp ib alpha (cd 42b) and gp ix (cd 42a) demonstrated the absence of gp ib alpha and presence of small amounts of gp ix on the surface of the patient's platelets. |
1995-02-14 |
2023-08-12 |
Not clear |
| R W Wood. Contributions of tryptophan side chains to the far-ultraviolet circular dichroism of proteins. European biophysics journal : EBJ. vol 23. issue 4. 1995-01-27. PMID:7805627. |
the observation that simple tryptophan derivatives such as n-acetyl-l-tryptophan methylamide have positive cd near 220 nm implies either that these derivatives prefer the alpha r region over the beta region, or that there is little preference for chi 2 < 180 degrees over chi 2 > 180 degrees. |
1995-01-27 |
2023-08-12 |
Not clear |
| I Safonova, U Reichert, B Shroot, G Ailhaud, P Grimald. Fatty acids and retinoids act synergistically on adipose cell differentiation. Biochemical and biophysical research communications. vol 204. issue 2. 1994-11-30. PMID:7980506. |
the most potent synergy was observed with compound cd 367, a potent agonist of rars as well as with compound am 580, a specific agonist of rar alpha. |
1994-11-30 |
2023-08-12 |
Not clear |
| I Safonova, U Reichert, B Shroot, G Ailhaud, P Grimald. Fatty acids and retinoids act synergistically on adipose cell differentiation. Biochemical and biophysical research communications. vol 204. issue 2. 1994-11-30. PMID:7980506. |
northern blot analysis of poly(a)+ mrna from cells treated with compound cd 367, alpha-bromopalmitate, or a combination of both agonists, did not show a dramatic effect, if any, on the expression of rar alpha, rar gamma, rxr alpha and rxr beta genes. |
1994-11-30 |
2023-08-12 |
Not clear |
| R MacColl, I Lam, C Y Choi, J Ki. Exciton splitting in phycoerythrin 545. The Journal of biological chemistry. vol 269. issue 41. 1994-11-17. PMID:7929246. |
the cd spectra of the separated alpha and beta polypeptides, under conditions where the polypeptide structure is denatured, have no negative bands. |
1994-11-17 |
2023-08-12 |
Not clear |
| M Congia, F Cucca, F Frau, R Lampis, L Melis, M G Clemente, A Cao, S De Virgilii. A gene dosage effect of the DQA1*0501/DQB1*0201 allelic combination influences the clinical heterogeneity of celiac disease. Human immunology. vol 40. issue 2. 1994-11-14. PMID:7928444. |
among the patients of group i, having the fully expressed form of cd and a mean age of 3 years at disease onset, a significant increase of drb1*0301, dqa1*0501, dqb1*0201 homozygotes, encoding in cis two dq (alpha 1*0501, beta 1*0201) susceptibility heterodimers, was observed when compared either with the patients of group ii (piii < 0.012) or with healthy individuals (pi < 10(-6)). |
1994-11-14 |
2023-08-12 |
Not clear |
| M Congia, F Cucca, F Frau, R Lampis, L Melis, M G Clemente, A Cao, S De Virgilii. A gene dosage effect of the DQA1*0501/DQB1*0201 allelic combination influences the clinical heterogeneity of celiac disease. Human immunology. vol 40. issue 2. 1994-11-14. PMID:7928444. |
genotype analysis showed that only three patients (all in group i) failed to form in trans or in cis the dq (alpha 1*0501, beta 1*0201) heterodimer and carried the dqa1*0101,dqb1*0501 haplotype, suggesting its possible role in cd susceptibility. |
1994-11-14 |
2023-08-12 |
Not clear |
| L H Conti, D G Costello, L A Martin, M F White, M E Abre. Mouse strain differences in the behavioral effects of corticotropin-releasing factor (CRF) and the CRF antagonist alpha-helical CRF9-41. Pharmacology, biochemistry, and behavior. vol 48. issue 2. 1994-10-20. PMID:8090821. |
the effect of the corticotropin-releasing factor (crf) antagonist alpha-helical crf9-41 (alpha h crf9-41; 25 and 50 micrograms) was examined in four strains of mice (balb/c, nih swiss, cf-1, and cd) in the elevated plus-maze anxiolytic test and found to significantly increase percent open arm activity in only the balb/c mice. |
1994-10-20 |
2023-08-12 |
mouse |