Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mayur Narkhede, Nancy L Bartlett, Sami Ibrahimi, Leslie Popplewell, Anna Seto, Jamie Bates, Yeonju Lee, Vaishnavi Ganti, Ling Han, Tianling Chen, Manish R Pate. A phase 1 first-in-human study of GS-0189, an anti-signal regulatory protein alpha (SIRPα) monoclonal antibody, in patients with relapsed/refractory (R/R) non-Hodgkin lymphoma (NHL). EJHaem. vol 4. issue 2. 2023-05-19. PMID:37206279. |
signal regulatory protein alpha (sirpα) is the receptor for cluster of differentiation (cd)47, a potent "don't eat me" signal for macrophages. |
2023-05-19 |
2023-08-14 |
Not clear |
Jie Gu, Kongdong Li, Hong Lin, Yanwei Wang, Yang Zhou, Dongfeng Chen, Xin Gu, Haifeng Sh. Cadmium induced immunosuppression through TLR-IκBα-NFκB signaling by promoting autophagic degradation. Ecotoxicology and environmental safety. vol 259. 2023-05-17. PMID:37196523. |
the results showed that cd exposure inhibited cona-induced the expressions of tumor necrosis factor alpha (tnf-α) and interferon gamma (ifn-γ) in mouse spleen tissues. |
2023-05-17 |
2023-08-14 |
mouse |
Razan Hayati Zulkeflee, Rosnah Bahar, Marne Abdullah, Muhammad Amiro Rasheeq Mohd Radzi, Alina Md Fauzi, Rosline Hassa. Application of Targeted Next-Generation Sequencing for the Investigation of Thalassemia in a Developing Country: A Single Center Experience. Diagnostics (Basel, Switzerland). vol 13. issue 8. 2023-05-16. PMID:37189480. |
other than that, cd 142 (hba2:c.427t>c) and another non-deletional alpha thalassemia and alpha triplication were also not picked up by the gap-pcr methods. |
2023-05-16 |
2023-08-14 |
Not clear |
Li-Jun Chen, Feng-Hua Tan, Zhe-Zhi Li, Wei Liu, Bo Ly. Contrasting responses of cuticular bacteria of Pardosa pseudoannulata under cadmium stress. Ecotoxicology and environmental safety. vol 255. 2023-03-29. PMID:36989947. |
the alpha diversity analysis showed that the high background of cd concentration (cd) reduced bacterial alpha diversity, and short-term cd (scd) stress elevated bacterial richness and diversity. |
2023-03-29 |
2023-08-14 |
spider |
Nicoletta Manzo, Giorgio Leodori, Giulia Ruocco, Daniele Belvisi, Shabbir Hussain I Merchant, Giovanni Fabbrini, Alfredo Berardelli, Antonella Cont. Cortical mechanisms of sensory trick in cervical dystonia. NeuroImage. Clinical. vol 37. 2023-02-15. PMID:36791488. |
differently, the "no touch", "passive", or "examiner touch" conditions did not show significant differences in eeg or emg changes determined by st execution/mimicking between cd patients with or without st. a higher desynchronization within alpha and theta bands in the sensorimotor and posterior parietal areas correlated with a more significant activity decrease in the contralateral scm muscle, findings from this study suggest that st-related changes in the activity of sensorimotor and posterior parietal areas may restore dystonic posture and that both motor and sensory components contribute to the st effect. |
2023-02-15 |
2023-08-14 |
Not clear |
Hua Yang, Yang Xun, Hua Yo. The landscape overview of CD47-based immunotherapy for hematological malignancies. Biomarker research. vol 11. issue 1. 2023-02-02. PMID:36726125. |
cluster of differentiation (cd) 47, which is found on both healthy and malignant cells, regulates macrophage-mediated phagocytosis by sending a "don't eat me" signal to the signal regulatory protein alpha (sirpα) receptor. |
2023-02-02 |
2023-08-14 |
Not clear |
Bauer O Alvarenga, Jacqueline B Paiva, Andrei I S Souza, Denise R Rodrigues, Polyana C Tizioto, Antonio J Piantino Ferreir. Metagenomics analysis of the morphological aspects and bacterial composition of broiler feces. Poultry science. vol 102. issue 2. 2022-12-24. PMID:36565637. |
the alpha diversity (shannon's index) revealed that the cd group showed greater diversity, and was significantly different from fp-2, fp-3, and rm-1. |
2022-12-24 |
2023-08-14 |
chicken |
Yu Chen, Guolin Zhang, Yuewen Yang, Shuangshuang Zhang, Haozheng Jiang, Kang Tian, Arenbaoligao, Dapeng Che. The treatment of inflammatory bowel disease with monoclonal antibodies in Asia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-12-08. PMID:36481399. |
since the 1997 report on the use of infliximab (a monoclonal antibody against tumor necrosis factor alpha [tnf-α]) in patients with cd, mabs have expanded therapeutic options and have also complicated initial management options and subsequent treatment. |
2022-12-08 |
2023-08-14 |
Not clear |
Nagasai Adusumilli, Jennifer Aronica, Frank Glass, Adam Friedma. Concurrent Interstitial Granulomatous Dermatitis and TNF-α Antagonist-Induced Lupus Syndrome Secondary to Adalimumab for Crohn's Disease. Journal of drugs in dermatology : JDD. vol 21. issue 11. 2022-11-07. PMID:36342727. |
here we report tnf-α antagonist-induced lupus syndrome (tails) revealed by interstitial granulomatous dermatitis (igd), in the atypical context of crohn's disease (cd). |
2022-11-07 |
2023-08-14 |
Not clear |
Marwa M M Refaie, Rehab Ahmed Rifaai, Michael Atef Fawzy, Sayed Shehat. Dapagliflozin Guards Against Cadmium-Induced Cardiotoxicity via Modulation of IL6/STAT3 and TLR2/TNFα Signaling Pathways. Cardiovascular toxicology. 2022-10-15. PMID:36242756. |
our data revealed that cd could induce cardiotoxicity with significant increase in serum cardiac enzymes, heart weight, tissue malondialdehyde (mda), tumor necrosis factor alpha (tnfα), nuclear factor kappa b (nfκb), toll like receptor2 (tlr2), interleukin 6 (il6) and caspase3 immunoexpression with abnormal histopathological changes. |
2022-10-15 |
2023-08-14 |
rat |
Kenneth Schmidt, Janelle Noel-MacDonnell, Carrie Vyhlidal, Daniel P Heruth, Vivekanand Singh, Atif A Ahmed, Taina Hudson, Veronica Williams, Valentina Shakhnovic. Characterization of the Mucosally-Adherent Duodenal Microbiome in Children with and without Crohn's Disease. Pharmaceuticals (Basel, Switzerland). vol 15. issue 7. 2022-07-27. PMID:35890149. |
bacterial relative abundance, alpha and beta composition, and diversity, were compared across duodenal and ti samples from the controls and cd groups with and without chronic active inflammation (118 samples from 73 children total; approx. |
2022-07-27 |
2023-08-14 |
Not clear |
Kyoung-Ho Oh, Seung-Hoon Le. COVID-19 and Fungal Diseases. Antibiotics (Basel, Switzerland). vol 11. issue 6. 2022-06-24. PMID:35740209. |
coronavirus disease-2019 (covid-19) can cause secondary bacterial and fungal infections by affecting the expression of pro-inflammatory markers, such as tumor necrosis alpha and certain cytokines, as well as the numbers of cd |
2022-06-24 |
2023-08-14 |
Not clear |
Eon-Joo Yun, Saba Imdad, Junho Jang, Jinhan Park, Byunghun So, Jin-Hee Kim, Chounghun Kan. Diet Is a Stronger Covariate than Exercise in Determining Gut Microbial Richness and Diversity. Nutrients. vol 14. issue 12. 2022-06-24. PMID:35745235. |
however, the shannon alpha diversity index was higher in the hfd and hfx groups than in the cd and ex groups. |
2022-06-24 |
2023-08-14 |
mouse |
Wenxue Wang, Zhongjian Liu, Wei Yue, Ling Zhu, Huijie Zhong, Chao Yang, Tian He, Ping Wan, Jiawei Gen. Mucosa-Colonizing Microbiota Correlate With Host Autophagy Signaling in Patients With Inflammatory Bowel Disease. Frontiers in microbiology. vol 13. 2022-06-13. PMID:35694307. |
we found the ulcerative colitis (uc) patients exhibited more severe dysbiosis than the crohn's disease (cd) patients, as represented by alpha diversity, community phenotypes, and functional annotation compared with the control population. |
2022-06-13 |
2023-08-14 |
Not clear |
Frode Lerang, René Holst, Magne Henriksen, Henrik Wåhlberg, Lars-Petter Jelsness-Jørgense. Antitumour necrosis factor alpha treatment in Crohn's disease: long-term efficacy, side effects and need for surgery. Scandinavian journal of gastroenterology. 2022-02-21. PMID:35188443. |
to examine the long-term efficacy and side effects of antitumour necrosis factor alpha (anti-tnf) therapy in patients with crohn's disease (cd), the need for surgery and the clinical outcome after discontinuing anti-tnf therapy. |
2022-02-21 |
2023-08-13 |
Not clear |
R Durga Priyadharshini, S Ponkarpagam, K N Vennila, Kuppanagounder P Elang. Spectroscopic and theoretical evidences for the surface binding of voglibose drug with DNA. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 271. 2022-01-22. PMID:35063822. |
binding of voglibose (vog), an alpha glucosidase inhibitor, with ct-dna has been investigated using various spectroscopic techniques including uv-vis, fluorescence and circular dichroism (cd) coupled with relative viscosity. |
2022-01-22 |
2023-08-13 |
Not clear |
Hui Li, Guolei Zhang, Wei Wang, Changbao Chen, Lili Jiao, Wei W. Preparation, Characterization, and Bioavailability of Host-Guest Inclusion Complex of Ginsenoside Re with Gamma-Cyclodextrin. Molecules (Basel, Switzerland). vol 26. issue 23. 2021-12-10. PMID:34885811. |
the solubility parameters of g-re in alpha (α), beta (β), and gamma (γ) cyclodextrin (cd) were investigated. |
2021-12-10 |
2023-08-13 |
Not clear |
Yan Deng, Shaodong Fu, Emmannuel Konadu Sarkodie, Shuangfei Zhang, Luhua Jiang, Yili Liang, Huaqun Yin, Lianyang Bai, Xueduan Liu, Hongwei Liu, Huidan Jian. Ecological responses of bacterial assembly and functions to steep Cd gradient in a typical Cd-contaminated farmland ecosystem. Ecotoxicology and environmental safety. vol 229. 2021-12-10. PMID:34890983. |
bacterial diversity and richness were significantly lower in highly polluted sites, and random forest analysis indicated that cd gradient played a decisive role in reducing alpha diversity. |
2021-12-10 |
2023-08-13 |
Not clear |
Naomi Karmi, Amber Bangma, Lieke M Spekhorst, Hendrik M van Dullemen, Marijn C Visschedijk, Gerard Dijkstra, Rinse K Weersma, Michiel D Voskuil, Eleonora A M Feste. Polygenetic risk scores do not add predictive power to clinical models for response to anti-TNFα therapy in inflammatory bowel disease. PloS one. vol 16. issue 9. 2021-11-18. PMID:34534227. |
anti-tumour necrosis factor alpha (tnfα) therapy is widely used in the management of crohn's disease (cd) and ulcerative colitis (uc). |
2021-11-18 |
2023-08-13 |
Not clear |
Chnasu Lee, Minae An, Je-Gun Joung, Woong-Yang Park, Dong Kyung Chang, Young-Ho Kim, Sung Noh Hon. TNFα Induces LGR5+ Stem Cell Dysfunction In Patients With Crohn's Disease. Cellular and molecular gastroenterology and hepatology. 2021-11-14. PMID:34700029. |
tumor necrosis factor alpha (tnfα) is considered a major tissue damage-promoting effector in crohn's disease (cd) pathogenesis. |
2021-11-14 |
2023-08-13 |
Not clear |