| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernanda da Silva Rodrigues, William Robert Newton, Isadora D'Ávila Tassinari, Felipe Henrique da Cunha Xavier, Adél Marx, Luciano Stürmer de Fraga, Karen Wright, Renata Padilha Guedes, Victorio Bambini-J. Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ. Neurochemistry international. 2024-05-18. PMID:38761855. |
cannabidiol prevents lps-induced inflammation by inhibiting the nlrp3 inflammasome and inos activity in bv2 microglia cells via cb2 receptors and pparγ. |
2024-05-18 |
2024-05-27 |
Not clear |
| Guanbo Xie, Xinwei Gao, Qingchun Guo, Haizhen Liang, Lan Yao, Wenjuan Li, Baiping Ma, Ning Wu, Xiao Han, Jin L. Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation through its action on CB2 receptors in the brain of male mice. Brain, behavior, and immunity. 2024-05-17. PMID:38759736. |
cannabidiol ameliorates ptsd-like symptoms by inhibiting neuroinflammation through its action on cb2 receptors in the brain of male mice. |
2024-05-17 |
2024-05-27 |
mouse |
| Maurício Dos Santos Pereira, Gabriel Henrique Dias de Abreu, Leonardo Calaça Arruda Vanderlei, Rita Raisman-Vozari, Francisco Silveira Guimarães, Hui-Chen Lu, Patrick Pierre Michel, Elaine Del Be. 4'-fluorocannabidiol associated with capsazepine restrains L-DOPA-induced dyskinesia in hemiparkinsonian mice: Contribution of anti-inflammatory and anti-glutamatergic mechanisms. Neuropharmacology. 2024-03-30. PMID:38554815. |
we tested the efficacy of 4'-fluorocannabidiol (4'-f-cbd), a semisynthetic cannabidiol derivative, and hu-910, a cannabinoid receptor 2 (cb2) agonist in resolving l-dopa-induced dyskinesia (lid). |
2024-03-30 |
2024-04-02 |
mouse |
| Shlok Bodke, Nachiket Joshi, Rajasekhar Reddy Alavala, Divya Suare. In silico exploration of CB2 receptor agonist in the management of neuroinflammatory conditions by pharmacophore modeling. Computational biology and chemistry. vol 110. 2024-03-20. PMID:38507844. |
in the present study, six different pharmacophore hypotheses were generated from cannabidiol (cbd)-cannabinoid receptor subtype-2 (cb2) and then zinc database was screened for identification of hit molecules. |
2024-03-20 |
2024-03-23 |
Not clear |
| Natalia Mansur Haddad, Leonardo Peroni De Jesus, Mauricio Serpa, Martinus Van De Bilt, Leda Talib, Alana Costa, Wagner Gattaz, Alexandre Andrade Loc. Endocannabinoid system alterations in schizophrenia: association with cannabis use and antipsychotic medication. European archives of psychiatry and clinical neuroscience. 2024-03-19. PMID:38502208. |
we found for the first time that cannabis use and non-clozapine antipsychotic medication are potentially involved in the modulation of the ecs, specifically influencing 2-ag endocannabinoid and cb2 receptor levels. |
2024-03-19 |
2024-03-23 |
Not clear |
| Mahla Masoumi, Mohammad Amin Manavi, Razieh Mohammad Jafari, Alireza Mirzaei, Keshvad Hedayatyanfard, Mohammad Taghi Beigmohammadi, Ahmad Reza Dehpou. Cannabidiol Anticonvulsant Effects Against Lithium-Pilocarpine-Induced Status Epilepticus in Male Rats Are Mediated by Neuroinflammation Modulation and Cannabinoids 1 (CB1), But Not CB2 and GABA Cannabis and cannabinoid research. 2023-11-17. PMID:37976207. |
cannabidiol anticonvulsant effects against lithium-pilocarpine-induced status epilepticus in male rats are mediated by neuroinflammation modulation and cannabinoids 1 (cb1), but not cb2 and gaba |
2023-11-17 |
2023-11-20 |
rat |
| Alexandre C Buffon, Daiana C Salm, Ana C Heymanns, Nathalia N Donatello, Débora C Martins, Jessica Francine Wichmann, Leandro Giacomello, Verônica V Horewicz, Daniel F Martins, Anna P Pioveza. Complex Regional Pain Syndrome Type I: Evidence for the CB1 and CB2 Receptors Immunocontent and Beneficial Effect of Local Administration of Cannabidiol in Mice. Cannabis and cannabinoid research. 2023-10-30. PMID:37903029. |
complex regional pain syndrome type i: evidence for the cb1 and cb2 receptors immunocontent and beneficial effect of local administration of cannabidiol in mice. |
2023-10-30 |
2023-11-08 |
mouse |
| Michael Maes, Muanpetch Rachayon, Ketsupar Jirakran, Atapol Sughondhabirom, Abbas F Almulla, Pimpayao Sodsa. Role of T and B lymphocyte cannabinoid type 1 and 2 receptors in major depression and suicidal behaviors. Acta neuropsychiatrica. 2023-09-08. PMID:37681553. |
this study examines the number of cannabinoid type 1 (cb1) and type 2 (cb2) receptor bearing t/b lymphocytes in mdd, and the effects of in vitro cannabidiol (cbd) administration on cb1/cb2-bearing immunocytes. |
2023-09-08 |
2023-10-07 |
Not clear |
| Ziteng Wang, Eric Yu Quan Leow, Hooi Yan Moy, Eric Chun Yong Cha. Advances in urinary biomarker research of synthetic cannabinoids. Advances in clinical chemistry. vol 115. 2023-09-06. PMID:37673518. |
synthetic cannabinoids (scs) are a subclass of nps which bind to the cannabinoid receptors, cb1 and cb2, and mimic the action of cannabis. |
2023-09-06 |
2023-10-07 |
human |
| Noa Raz, Aharon M Eyal, Dana Berneman Zeitouni, Danielle Hen-Shoval, Elyad M Davidson, Aviel Danieli, Merav Tauber, Yair Ben-Chai. SELECTED CANNABIS TERPENES SYNERGIZE WITH THC TO PRODUCE INCREASED CB1 RECEPTOR ACTIVATION. Biochemical pharmacology. 2023-04-21. PMID:37084981. |
the cannabis plant exerts its pharmaceutical activity primarily by the binding of cannabinoids to two g protein-coupled cannabinoid receptors, cb1 and cb2. |
2023-04-21 |
2023-08-14 |
Not clear |
| Elham Haghparast, Vahid Sheibani, Gholamreza Komeili, Mohadeseh Chahkandi, Nahid Sepehri Ra. The Effects of Chronic Marijuana Administration on 6-OHDA-Induced Learning & Memory Impairment and Hippocampal Dopamine and Cannabinoid Receptors Interaction in Male Rats. Neurochemical research. 2023-03-09. PMID:36894794. |
marijuana consumption caused a significant decrease in cb1 mrna level and an increase in cb2 mrna level in 6-ohda + marijuana group. |
2023-03-09 |
2023-08-14 |
rat |
| Lucas Antônio Dos Santos Barbosa, Rafael Cypriano Dutra, Eduardo Luiz Gasnhar Moreira, Cristiane Ribeiro de Carvalh. β-caryophyllene, a cannabinoid receptor 2 agonist, decreases the motivational salience and conditioning place preference for palatable food in female mice. Addiction biology. vol 28. issue 1. 2022-12-28. PMID:36577722. |
β-caryophyllene (bcp) is a cannabinoid receptor cb2 agonist plant-derived terpenoid found in different essential oil plants, including rosemary, black pepper, copaiba and cannabis. |
2022-12-28 |
2023-08-14 |
mouse |
| Laura M Navarro-Saiz, Lilia J Bernal-Cepeda, Jaime E Castellano. Immune challenges upregulate the expression of cannabinoid receptors in cultured human odontoblasts and gingival fibroblasts. Acta odontologica latinoamericana : AOL. vol 35. issue 2. 2022-10-19. PMID:36260938. |
cb1 and cb2 transcription was analyzed by real-time pcr, proteins were detected by immunofluorescence, and functional cannabinoid receptors were evaluated by measuring intracellular calcium concentration after stimulation with cannabidiol (cbd) and pre-treatment with a cb1 antagonist, a cb2 inverse agonist and a trpv1 antagonist. |
2022-10-19 |
2023-08-14 |
human |
| Xiaoqin Zhan, Chris Drummond-Main, Dylan Greening, Jinjing Yao, S W R Chen, J P Appendino, P Y Billie Au, Ray W Turne. Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant. iScience. vol 25. issue 10. 2022-09-26. PMID:36157585. |
cannabidiol (1 μm) offset the effects of kv7.2mut by inducing a hyperpolarizing shift in voltage for activation independent of cb1 or cb2 receptors. |
2022-09-26 |
2023-08-14 |
Not clear |
| Jaqueline M Franzen, Felipe Vanz, Isabel Werle, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol impairs fear memory reconsolidation in female rats through dorsal hippocampus CB1 but not CB2 receptor interaction. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 64. 2022-09-01. PMID:36049316. |
cannabidiol impairs fear memory reconsolidation in female rats through dorsal hippocampus cb1 but not cb2 receptor interaction. |
2022-09-01 |
2023-08-14 |
rat |
| Hayder M Al-Kuraishy, Ali I Al-Gareeb, Athanasios Alexiou, Gaber El-Saber Batih. Cannabinoids receptors in Covid-19: Perpetrators and victims. Current medicinal chemistry. 2022-08-31. PMID:36043749. |
cannabinoids (cbs) such as tetrahydrocannabinol (thc) and cannabidiol (cbd), which act on g-protein-coupled receptors called cb1 and cb2, have anti-inflammatory effects. |
2022-08-31 |
2023-08-14 |
Not clear |
| Mahendra Kumar Trivedi, Sambhu Mondal, Snehasis Jan. Cannabidiol improves thyroid function via modulating vitamin D Journal of food science and technology. vol 59. issue 8. 2022-07-25. PMID:35872737. |
cannabidiol improves thyroid function via modulating vitamin d the study was evaluated the impact of cannabidiol (cbd) on thyroid hormones by modulation cannabinoid receptor-2 (cb2) and vitamin d receptor (vdr) in rats fed with vitamin d |
2022-07-25 |
2023-08-14 |
rat |
| Valéria de Almeida, Gabriela Seabra, Guilherme Reis-de-Oliveira, Giuliana S Zuccoli, Priscila Rumin, Mariana Fioramonte, Bradley J Smith, Antonio W Zuardi, Jaime E C Hallak, Alline C Campos, José A Crippa, Daniel Martins-de-Souz. Cannabinoids modulate proliferation, differentiation, and migration signaling pathways in oligodendrocytes. European archives of psychiatry and clinical neuroscience. 2022-05-27. PMID:35622101. |
mass spectrometry-based shotgun proteomics and in silico biology tools were used to determine which signaling pathways and molecular mechanisms are triggered in a human oligodendrocytic cell line (mo3.13) by several pharmacological stimuli: the phytocannabinoid cannabidiol (cbd); cb1 and cb2 agonists acea, hu308, and win55, 212-2; cb1 and cb2 antagonists am251 and am630; and endocannabinoids anandamide (aea) and 2-arachidonoylglycerol (2-ag). |
2022-05-27 |
2023-08-13 |
human |
| Vittoria Borgonetti, Cristina Benatti, Paolo Governa, Giovanni Isoldi, Federica Pellati, Silvia Alboni, Fabio Tascedda, Monica Montopoli, Nicoletta Galeotti, Fabrizio Manetti, Elisabetta Miraldi, Marco Biagi, Giovanna Rigill. Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids-, and NF-κB-mediated signaling. Phytotherapy research : PTR. 2022-04-08. PMID:35393641. |
non-psychotropic cannabis sativa l. phytocomplex modulates microglial inflammatory response through cb2 receptors-, endocannabinoids-, and nf-κb-mediated signaling. |
2022-04-08 |
2023-08-13 |
Not clear |
| Petr Jirasek, Alexandr Jusku, Vilim Simanek, Jana Frankova, Jan Storch, Jan Vace. Cannabidiol and periodontal inflammatory disease: A critical assessment. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 2022-03-25. PMID:35332345. |
cannabidiol (cbd), a non-psychotropic cannabinoid produced by the genus cannabis, is a phytoceutical that activates the endocannabinoid system (ecs) through binding to cb1 and cb2 receptors. |
2022-03-25 |
2023-08-13 |
Not clear |