| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C R Plata-Salamán, Y Oomur. Calcitonin as a feeding suppressant: localization of central action to the cerebral III ventricle. Physiology & behavior. vol 40. issue 4. 1987-10-13. PMID:3628547. |
the evidence suggests that the hypothalamus is a main locus for suppression of food intake by icv administered calcitonin. |
1987-10-13 |
2023-08-11 |
rat |
| R de Beaurepaire, W J Free. Regional localization of the antagonism of amphetamine-induced hyperactivity by intracerebral calcitonin injections. Pharmacology, biochemistry, and behavior. vol 27. issue 1. 1987-08-28. PMID:3615541. |
the areas where calcitonin is most effective in decreasing locomotor activity are located in the hypothalamus and nucleus accumbens, suggesting that these areas are the major sites of action of calcitonin in inhibiting amphetamine-induced locomotor activity. |
1987-08-28 |
2023-08-11 |
Not clear |
| Y Taché, E Kolve, G Kauffma. Potent CNS action of calcitonin to inhibit cysteamine-induced duodenal ulcers in rat. Life sciences. vol 41. issue 5. 1987-08-20. PMID:3600197. |
specific binding sites have been demonstrated for calcitonin in the hypothalamus, brain stem and dorsal horn of the spinal cord using homogenate and membrane preparations or in vitro autoradiography methods. |
1987-08-20 |
2023-08-11 |
rat |
| K K Pun, Z Varghese, J F Moorhea. Reduction of serum prolactin after salmon calcitonin infusion in patients with impaired renal function. Acta endocrinologica. vol 115. issue 2. 1987-08-19. PMID:3604555. |
recently human calcitonin gene-related peptide, produced by alternative rna processing from the calcitonin gene, was shown to have structural homology to salmon calcitonin and probably have a modulator function in the hypothalamus. |
1987-08-19 |
2023-08-11 |
human |
| A M Lengyel, G S Tannenbau. Mechanisms of calcitonin-induced growth hormone (GH) suppression: roles of somatostatin and GH-releasing factor. Endocrinology. vol 120. issue 4. 1987-04-27. PMID:2881773. |
calcitonin (ct) binds to specific receptors in the hypothalamus and has been localized in the pituitary, suggesting a potential neuroendocrine role for this peptide. |
1987-04-27 |
2023-08-11 |
rat |
| S Nicosia, F Guidobono, M Musanti, A Pecil. Inhibitory effects of calcitonin on adenylate cyclase activity in different rat brain areas. Life sciences. vol 39. issue 23. 1987-01-15. PMID:3023780. |
salmon calcitonin (sct) dose-dependently inhibited the enzyme activity in midbrain, hypothalamus, medulla, pons and caudate nucleus, but was ineffective in adenohypophysis. |
1987-01-15 |
2023-08-11 |
human |
| J A Fischer, W Bor. Novel peptides from the calcitonin gene: expression, receptors and biological function. Peptides. vol 6 Suppl 3. 1986-05-15. PMID:3008119. |
cgrp receptors are present in the brain and the heart, and calcitonin receptors in bone and kidney cells and in the hypothalamus. |
1986-05-15 |
2023-08-11 |
Not clear |
| S Shimada, S Shiosaka, P C Emson, C J Hillyard, S Girgis, I MacIntyre, M Tohyam. Calcitonin gene-related peptidergic projection from the parabrachial area to the forebrain and diencephalon in the rat: an immunohistochemical analysis. Neuroscience. vol 16. issue 3. 1986-03-28. PMID:3912674. |
destruction of the ventral portion of the parabrachial area resulted in a marked decrease of fibers containing calcitonin gene-related peptide in the bed nucleus of the stria terminalis, the central amygdaloid nucleus and the lateral hypothalamus just medial to the crus cerebri (the far-lateral hypothalamus), and a less marked decrease in the ventromedial thalamic nucleus. |
1986-03-28 |
2023-08-11 |
rat |
| M J Twery, R L Mos. Calcitonin and calcitonin gene-related peptide alter the excitability of neurons in rat forebrain. Peptides. vol 6. issue 3. 1986-01-03. PMID:3877916. |
individual neurons in the hypothalamus, thalamus, cortex, and other forebrain areas of urethane-anesthetized, male rats were iontophoretically tested for their membrane sensitivity to salmon calcitonin (ct), human ct, and ct gene-related peptide (cgrp). |
1986-01-03 |
2023-08-11 |
human |
| M Sakanaka, S Magari, P C Emson, C J Hillyard, S I Girgis, I MacIntyre, M Tohyam. The calcitonin gene-related peptide-containing fiber projection from the hypothalamus to the lateral septal area including its fine structures. Brain research. vol 344. issue 1. 1985-11-12. PMID:3899279. |
the calcitonin gene-related peptide-containing fiber projection from the hypothalamus to the lateral septal area including its fine structures. |
1985-11-12 |
2023-08-11 |
rat |
| T Mitsuma, T Nogimori, M Chay. Peripheral administration of eel calcitonin inhibits thyrotropin secretion in rats. European journal of pharmacology. vol 102. issue 1. 1984-11-13. PMID:6434328. |
the findings suggest that calcitonin acts on both the hypothalamus and the pituitary to inhibit trh and tsh release, and that its effects may be modified by amines of the central nervous system. |
1984-11-13 |
2023-08-12 |
rat |
| W J Freed, R de Beaurepair. Calcitonin as an anorectic agent: localization of the effect to the brain and the hypothalamus. Psychopharmacology bulletin. vol 20. issue 3. 1984-10-03. PMID:6473648. |
calcitonin as an anorectic agent: localization of the effect to the brain and the hypothalamus. |
1984-10-03 |
2023-08-12 |
Not clear |
| V R Olgiati, F Guidobono, C Netti, A Pecil. Localization of calcitonin binding sites in rat central nervous system: evidence of its neuroactivity. Brain research. vol 265. issue 2. 1983-07-15. PMID:6850324. |
the distribution of calcitonin (ct) binding sites in serial sections of the rat brain and spinal cord has been examined by an 'in vitro' autoradiographic technique using a radioisotope-sensitive sheet film and [125]salmon ct. autoradiograms of the diencephalic region had the highest grain density throughout the entire hypothalamus, with the exception of the nuclei ventromedialis, posterior and mammillaris, which were not labeled at all. |
1983-07-15 |
2023-08-12 |
rat |
| M Koida, Y Yamamoto, H Nakamuta, J Matsuo, M Okamoto, T Morimoto, J K Seyler, R C Orlowsk. A novel effect of salmon calcitonin on in vitro Ca-uptake by rat brain hypothalamus: the regional and hormonal specificities. Japanese journal of pharmacology. vol 32. issue 6. 1983-04-15. PMID:7161972. |
a novel effect of salmon calcitonin on in vitro ca-uptake by rat brain hypothalamus: the regional and hormonal specificities. |
1983-04-15 |
2023-08-12 |
rat |
| D G MacInnes, I Laszlo, I MacIntyre, G Fin. Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter. Brain research. vol 251. issue 2. 1983-01-27. PMID:7139333. |
recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence of high concentrations of calcitonin in the nerve varicosities and terminals of the hypothalamus and in particular the median eminence of the lizard lacertus muralis. |
1983-01-27 |
2023-08-12 |
Not clear |
| M van Houten, A J Rizzo, D Goltzman, B I Posne. Brain receptors for blood-borne calcitonin in rats: circumventricular localization and vasopressin-resistant deficiency in hereditary diabetes insipidus. Endocrinology. vol 111. issue 5. 1982-12-16. PMID:6290196. |
by this method, using normal long-evans rats as controls, specific binding of blood-borne calcitonin in the median eminence region of the hypothalamus was reduced by one-third in homozygous brattleboro rats, which are genetically deficient in vasopressin. |
1982-12-16 |
2023-08-12 |
rat |
| S G Amara, V Jonas, M G Rosenfeld, E S Ong, R M Evan. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature. vol 298. issue 5871. 1982-08-26. PMID:6283379. |
the calcitonin mrna predominates in the thyroid while the cgrp-specific mrna appears to predominate in the hypothalamus. |
1982-08-26 |
2023-08-12 |
Not clear |
| J A Fischer, P H Tobler, M Kaufmann, W Born, H Henke, P E Cooper, S M Sagar, J B Marti. Calcitonin: regional distribution of the hormone and its binding sites in the human brain and pituitary. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 12. 1982-05-21. PMID:6950419. |
immunoreactive calcitonin (ct), indistinguishable from human ct-(1-32) and its sulfoxide, has been identified in extracts of the hypothalamus, the pituitary, and the thyroid obtained from human subjects at autopsy. |
1982-05-21 |
2023-08-12 |
human |
| J J Flynn, D L Margules, C W Coope. Presence of immunoreactive calcitonin in the hypothalamus and pituitary lobes of rats. Brain research bulletin. vol 6. issue 6. 1981-09-15. PMID:7248819. |
presence of immunoreactive calcitonin in the hypothalamus and pituitary lobes of rats. |
1981-09-15 |
2023-08-12 |
rat |
| J J Flynn, D L Margules, C W Coope. Presence of immunoreactive calcitonin in the hypothalamus and pituitary lobes of rats. Brain research bulletin. vol 6. issue 6. 1981-09-15. PMID:7248819. |
the recent report of the occurrence of calcitonin receptors in the hypothalamus and other brain regions in conjunction with our finding of calcitonin-like immunoreactivity in the hypothalamus suggests that calcitonin-like molecules may be active within the brain. |
1981-09-15 |
2023-08-12 |
rat |