| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Roberts, M Levy, P G Chioros, B G Bartlow, J Forristal, C D West, R Habib, E J Lewi. A serum C3-activating factor: its characterization and its presence in glomerular deposits. Journal of immunology (Baltimore, Md. : 1950). vol 127. issue 3. 1981-10-29. PMID:7021675. |
normal human serums contain an alpha 2 protein that shows complete antigenic identity with the gamma protein of c3af, but this alpha 2 protein lacks c3 activating function. |
1981-10-29 |
2023-08-12 |
human |
| I Gigli, J Sorvillo, L Mecarelli-Halbwachs, J Leibowitc. Mechanism of action of the C4 nephritic factor. Deregulation of the classical pathway of C3 convertase. The Journal of experimental medicine. vol 154. issue 1. 1981-09-22. PMID:7019379. |
three mechanisms that regulate the formation and function of the classical pathway c3 convertase (c4b2a) have been elucidated: (a) an intrinsic decay of the enzyme that is temperature dependent; (b) an extrinsic decay mediated by the effect of the serum protein c4b binding protein (c4-bp); and (c) inactivation of c4b by the proteolytic action of c4b/c3b inactivator (c4b/c3bina), which cleaves that alpha' chain of c4b to yield c4d (alpha 2) and c4c (alpha 3, alpha 4, beta, and gamma chains). |
1981-09-22 |
2023-08-12 |
Not clear |
| D Y Bell, J A Haseman, A Spock, G McLennan, G E Hoo. Plasma proteins of the bronchoalveolar surface of the lungs of smokers and nonsmokers. The American review of respiratory disease. vol 124. issue 1. 1981-09-15. PMID:6789730. |
smoking did not cause a significant change in the concentration of any protein in serum, but did cause an increase in igg, c4, and c3 and a decrease in alpha 2-thioglycoprotein, alpha 1-acid glycoprotein, and gc-globulin in lavage effluents from females. |
1981-09-15 |
2023-08-12 |
Not clear |
| T Seya, S Nagasaw. Limited proteolysis of the third component of human complement, C3, by heat treatment. Journal of biochemistry. vol 89. issue 2. 1981-08-20. PMID:7240134. |
human c3 is composed of two disulfide-linked polypeptide chains, termed alpha chain (with a molecular weight of 110,000) and beta chain (with a molecular weight of 75,000). |
1981-08-20 |
2023-08-12 |
human |
| G C Angela, A Tosco, R Giannone, G Magliacani, E Raiter. [Behavior of complement factors and plasma proteins in burns]. Archivio per le scienze mediche. vol 138. issue 1. 1981-08-10. PMID:6166276. |
the behaviour of three complement components (c3, c4 and c3 activator), alpha 1, alpha 2, iga, igg, igm, total proteins, and gamma globulins was followed 114 patients at the c.t.o. |
1981-08-10 |
2023-08-12 |
Not clear |
| A Mód, G Füst, J Gergely, S R Hollán, M P Dieric. Alpha-1-antitrypsin-induced inhibition of complement-dependent phagocytosis. Immunobiology. vol 158. issue 4. 1981-08-10. PMID:7016739. |
in a previous investigation, inhibition of complement-dependent rosette formation by alpha 1-antitrypsin (alpha 1-at) was observed, and it was demonstrated that alpha 1-at interacts through its carbohydrate portion with c3 and its fragments. |
1981-08-10 |
2023-08-12 |
human |
| A Mód, G Füst, J Gergely, S R Hollán, M P Dieric. Alpha-1-antitrypsin-induced inhibition of complement-dependent phagocytosis. Immunobiology. vol 158. issue 4. 1981-08-10. PMID:7016739. |
it was demonstrated that alpha 1-at towards c3 and fragments of c3 was not mediated by its antiprotease effect, but by its carbohydrate moiety. |
1981-08-10 |
2023-08-12 |
human |
| C Y Chuang, W Y Chen, T S Yen, B S Hsieh, C S Lee, S F Luo, K T Lin, C Y Che. Simultaneous studies of serum and urinary proteins for evaluation and diagnosis of glomerular damages in proteinuric patients. Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology. vol 13. issue 4. 1981-07-23. PMID:7226987. |
in the groups of acute glomerulonephritis and lupus nephropathy, c3 was generally decreased; polyclonal gammopathy was frequently encountered and alpha 1 acid glycoprotein was markedly increased. |
1981-07-23 |
2023-08-12 |
Not clear |
| C Y Chuang, W Y Chen, T S Yen, B S Hsieh, C S Lee, S F Luo, K T Lin, C Y Che. Simultaneous studies of serum and urinary proteins for evaluation and diagnosis of glomerular damages in proteinuric patients. Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology. vol 13. issue 4. 1981-07-23. PMID:7226987. |
in the cases of chronic glomerulonephritis and diabetic nephropathy and the levels of gamma globulin, c3 and alpha 2 acid glycoprotein were usually within normal limits. |
1981-07-23 |
2023-08-12 |
Not clear |
| H Frit. Proteinase inhibitors in severe inflammatory processes (septic shock and experimental endotoxaemia): biochemical, pathophysiological and therapeutic aspects. Ciba Foundation symposium. issue 75. 1981-03-24. PMID:399895. |
a similar statistically significant reduction of the concentrations of several plasma factors (prothrombin and antithrombin iii, plasminogen and alpha 2-plasmin inhibitor, complement factor c3 and clotting factor xiii) was observed in experimental endotoxaemia. |
1981-03-24 |
2023-08-11 |
human |
| M Imbriani, G Catenacc. Immunological parameters in farmers with chronic lung disease. Broncho-pneumologie. vol 30. issue 4. 1981-03-24. PMID:7448600. |
the serum concentrations of igg, iga, ige, c3 (b1a), c4 and alpha 1 at were measured in 8 farmers with chronic pneumopathy, who showed precipitins against m. faeni or t. vulgaris in the serum. |
1981-03-24 |
2023-08-12 |
human |
| B Wüthrich, P J Grob, S Zisiadi. [Immunological study of alopecia areata]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. vol 31. issue 9. 1981-03-17. PMID:6969719. |
the mean values of igg, iga, igm, ige, complement factors c3 and c4 and of alpha 1-antitrypsin were found within the norm, of the c1-inhibitor slight diminished. |
1981-03-17 |
2023-08-12 |
Not clear |
| B F Tack, R A Harrison, J Janatova, M L Thomas, J W Prah. Evidence for presence of an internal thiolester bond in third component of human complement. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 10. 1981-02-26. PMID:6934510. |
autoradiographic analyses of [14c]methylamine-treated c3 and methylamine-inactivated [1-14c]carboxyamidomethylated c3 after nadodso4/polyacrylamide gel electrophoresis have shown a specific incorporation of each radiolabel into the alpha polypeptide chain. |
1981-02-26 |
2023-08-12 |
human |
| C L Martin, L M Pachma. Synovial fluid in seronegative juvenile rheumatoid arthritis: studies of immunoglobulins, complements, and alpha 2-macroglobulin. Arthritis and rheumatism. vol 23. issue 11. 1981-02-24. PMID:6160859. |
when adjusted for total protein, synovial levels of total hemolytic complement, c3, c4, and alpha 2-m did not differ significantly in the two groups. |
1981-02-24 |
2023-08-12 |
Not clear |
| R Anderson, I Hay, H van Wyk, R Oosthuizen, A Thero. The effect of ascorbate on cellular humoral immunity in asthmatic children. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 58. issue 24. 1981-02-19. PMID:7444701. |
humoral functions measured were secretory iga, serum immunoglobulins, alpha 1-antitrypsin, c3, c4 and total haemolytic complement, antistreptolysin o (aso) and c-reactive protein. |
1981-02-19 |
2023-08-12 |
cat |
| S K Al-Agidi, D F Robert. Serum protein levels in Iraq. Transactions of the Royal Society of Tropical Medicine and Hygiene. vol 74. issue 3. 1981-01-26. PMID:6159703. |
the sample comprised 1,031 subjects who were examined for the following: igg, m, a and e; the components c3, c4 and c3 proactivator of complement; alpha 2 globulin, albumin and total protein. |
1981-01-26 |
2023-08-12 |
human |
| J Janatova, P E Lorenz, A N Schechter, J W Prahl, B F Tac. Third component of human complement: appearance of a sulfhydryl group following chemical or enzymatic inactivation. Biochemistry. vol 19. issue 19. 1980-11-25. PMID:7407085. |
autoradiography of the electrophoretogram of separated alpha-, alpha'-, and beta-polypeptide chains of inactivated, [1-14c]carboxamidomethylated c3 samples has shown that the reactive sulfhydryl group is present in the alpha chain of c3 and in the alpha' chain of c3b, respectively. |
1980-11-25 |
2023-08-12 |
human |
| D E Isenman, J S Sundsmo, N R Coope. The effects of mild reduction on the structure and function of C3. Journal of immunology (Baltimore, Md. : 1950). vol 125. issue 4. 1980-11-25. PMID:7410856. |
the loss in lytic activity correlated with the alkylation of approximately 6 liberated sulfhydryls, all of which arose from intrachain disulfides in the alpha polypeptide chain of c3. |
1980-11-25 |
2023-08-12 |
Not clear |
| E S Zemel, C M Cartwright-Harwick, U R Nilsso. Effect of reduction on the structural, biologic, and immunologic properties of the third component of human complement. Journal of immunology (Baltimore, Md. : 1950). vol 125. issue 3. 1980-11-20. PMID:7410831. |
sulfhydryl analysis reveals that two disulfide bonds, both presumed to be situated in the c3 alpha subunit, are broken: one at 2.2 x 10(-2) m and one at 3.5 x 10(-2) m nabh4. |
1980-11-20 |
2023-08-12 |
human |
| E S Zemel, C M Cartwright-Harwick, U R Nilsso. Effect of reduction on the structural, biologic, and immunologic properties of the third component of human complement. Journal of immunology (Baltimore, Md. : 1950). vol 125. issue 3. 1980-11-20. PMID:7410831. |
sulfhydryl analysis indicates the cleavage of four disulfide bonds; three bonds within c3 alpha and beta are broken at 5.0 x 10(-4) m dtt, and one additional bond within c3 alpha at 1.0 x 10(-3) m dtt. |
1980-11-20 |
2023-08-12 |
human |