| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Di Renzo, M R De Cristofaro, A Zicari, R Viola, G Pontieri, M Lipar. IFN gamma and TNF alpha cause an increased release of C3 by murine macrophages. Immunology letters. vol 42. issue 3. 1995-04-20. PMID:7890316. |
ifn gamma and tnf alpha cause an increased release of c3 by murine macrophages. |
1995-04-20 |
2023-08-12 |
mouse |
| L Di Renzo, M R De Cristofaro, A Zicari, R Viola, G Pontieri, M Lipar. IFN gamma and TNF alpha cause an increased release of C3 by murine macrophages. Immunology letters. vol 42. issue 3. 1995-04-20. PMID:7890316. |
recombinant ifn gamma and tnf alpha were strong inducers of c3 release, while il-2 acted poorly. |
1995-04-20 |
2023-08-12 |
mouse |
| L Di Renzo, M R De Cristofaro, A Zicari, R Viola, G Pontieri, M Lipar. IFN gamma and TNF alpha cause an increased release of C3 by murine macrophages. Immunology letters. vol 42. issue 3. 1995-04-20. PMID:7890316. |
taken together, these results show that murine macrophages increase the release of c3 molecules upon treatment with ifn gamma or tnf alpha and that these cytokines released in vivo by splenocytes from tumor bearing mice may account, together with a yet unknown factor, for a humoral network causing the increased release of c3 by peritoneal macrophages. |
1995-04-20 |
2023-08-12 |
mouse |
| M R Jacquier-Sarlin, F M Gabert, M B Villiers, M G Colom. Modulation of antigen processing and presentation by covalently linked complement C3b fragment. Immunology. vol 84. issue 1. 1995-04-18. PMID:7890301. |
ligands such as complement fragments (c3, c4), igg or alpha 2-macroglobulin, which bind antigen (ag) before their uptake by antigen-presenting cells (apc), are likely to modulate the different steps of ag processing and presentation. |
1995-04-18 |
2023-08-12 |
human |
| M R Jacquier-Sarlin, F M Gabert, M B Villiers, M G Colom. Modulation of antigen processing and presentation by covalently linked complement C3b fragment. Immunology. vol 84. issue 1. 1995-04-18. PMID:7890301. |
complement protein c3 contains, like other members of the alpha 2-macroglobulin family, an intrachain thiolester bond. |
1995-04-18 |
2023-08-12 |
human |
| S Tsuji, K Kaji, S Nagasaw. Activation of the alternative pathway of human complement by apoptotic human umbilical vein endothelial cells. Journal of biochemistry. vol 116. issue 4. 1995-04-10. PMID:7883753. |
c3 contains an intrachain thioester bond in the alpha chain (110 kda) and upon activation to c3b, binds with membrane molecules by forming an ester or amide bond. |
1995-04-10 |
2023-08-12 |
human |
| D E Cummings, S Edelhoff, C M Disteche, G S McKnigh. Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms. Mammalian genome : official journal of the International Mammalian Genome Society. vol 5. issue 11. 1995-03-31. PMID:7873880. |
this is displaced from its functional homologs, c alpha and c beta, which we map to mouse chrs 8 (band c3) and 3 (band h3), respectively. |
1995-03-31 |
2023-08-12 |
mouse |
| M Mavroidis, J O Sunyer, J D Lambri. Isolation, primary structure, and evolution of the third component of chicken complement and evidence for a new member of the alpha 2-macroglobulin family. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 5. 1995-03-29. PMID:7532662. |
in this study, we present the complete cdna sequence of chicken c3, the cdna sequences of the thioester region for two chicken alpha 2-macroglobulin (alpha 2m)-related proteins, a simplified method for purifying chicken c3, and an analysis of the c3 convertase and factor i-mediated cleavages in chicken c3. |
1995-03-29 |
2023-08-12 |
mouse |
| M Mavroidis, J O Sunyer, J D Lambri. Isolation, primary structure, and evolution of the third component of chicken complement and evidence for a new member of the alpha 2-macroglobulin family. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 5. 1995-03-29. PMID:7532662. |
using the reverse-transcriptase pcr, with degenerate oligonucleotide primers derived from two conserved c3 sequences (gcgeqn/tm, twltay/fv) and liver mrna as template, we isolated three distinct 220-bp pcr products, one with a high degree of sequence similarity to c3 and two to alpha 2m and pregnancy zone protein from other species. |
1995-03-29 |
2023-08-12 |
mouse |
| M Mavroidis, J O Sunyer, J D Lambri. Isolation, primary structure, and evolution of the third component of chicken complement and evidence for a new member of the alpha 2-macroglobulin family. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 5. 1995-03-29. PMID:7532662. |
a phylogenetic tree for c3, c4, c5, and alpha 2m-related proteins was constructed based on the sequence data and is discussed. |
1995-03-29 |
2023-08-12 |
mouse |
| R T Ogata, P J Low, M Kawakam. Substrate specificities of the protease of mouse serum Ra-reactive factor. Journal of immunology (Baltimore, Md. : 1950). vol 154. issue 5. 1995-03-29. PMID:7868903. |
our results revealed that rarf preferentially cleaves the c4 alpha-chain with specific activities 20- to 100-fold greater than either human or murine c1s, and that rarf also cleaves the c3 alpha-chain, but with a lower efficiency than c4 alpha. |
1995-03-29 |
2023-08-12 |
mouse |
| B Azadeh, N Baghoumian, O T el-Bakr. Rhinosporidiosis: immunohistochemical and electron microscopic studies. The Journal of laryngology and otology. vol 108. issue 12. 1995-03-20. PMID:7861079. |
early nodular bodies were immunohistochemically positive for alpha 1-at, alpha 1-act, cea, s100, fibronectin, amyloid-p-component, igg, iga, c1q and c3. |
1995-03-20 |
2023-08-12 |
Not clear |
| C U Brand, P J Späth, T Hunziker, A Limat, L R Braathe. Complement profiles in human skin lymph during the course of irritant contact dermatitis. Archives of dermatological research. vol 286. issue 7. 1995-02-09. PMID:7818276. |
in comparison to the baseline, the mean values for c1q, c1r, c2, c5, c6, c7, c8, c9, fb, c1inh, c4bp, fh and fi exhibited a 3-5-fold increase, c3, total c4, albumin and the alpha 1-globulin fraction a 6-9-fold increase, and c1s, c4a, c4b, fb and alpha 2-, beta- and gamma-globulins a 10-20-fold increase. |
1995-02-09 |
2023-08-12 |
human |
| C A Rey-Millet, C L Villiers, F M Gabert, S Chesne, M G Colom. C3b covalently associated to tetanus toxin modulates TT processing and presentation by U937 cells. Molecular immunology. vol 31. issue 17. 1995-01-13. PMID:7997244. |
complement protein c3, like c4 and alpha 2-macroglobulin (alpha 2m), is a potentially bivalent ligand: (1) its proteolytic fragment, c3b, is able to interact covalently with antigens, and (2) this bound fragment is able to interact non-covalently with specific complement receptors of antigen presenting cells (apc). |
1995-01-13 |
2023-08-12 |
Not clear |
| Y Cahen-Kramer, I L Mårtensson, F Melcher. The structure of an alternate form of complement C3 that displays costimulatory growth factor activity for B lymphocytes. The Journal of experimental medicine. vol 180. issue 6. 1994-12-23. PMID:7964485. |
this alternate c3 message contains an open reading frame that may encode a 536-amino acid-long protein identical to the 3' part of the c3 alpha chain. |
1994-12-23 |
2023-08-12 |
mouse |
| Z Lao, Y Wang, M Mavroidis, I Kostavasili, J D Lambri. Overexpression, purification, and characterization of third component of complement. Journal of immunological methods. vol 176. issue 1. 1994-12-16. PMID:7963591. |
characterization of the recombinant c3 (rc3) by sds-page revealed that the c3 gene product was translated as a 188 kda protein comprised of two chains of 115 kda and 73 kda analogous to the alpha and beta chains of serum-derived human c3 (sc3). |
1994-12-16 |
2023-08-12 |
human |
| M T Assakura, A P Reichl, F R Mandelbau. Isolation and characterization of five fibrin(ogen)olytic enzymes from the venom of Philodryas olfersii (green snake). Toxicon : official journal of the International Society on Toxinology. vol 32. issue 7. 1994-10-27. PMID:7940589. |
pofibc1, c2, c3 and h degraded preferentially a alpha-chains while pofibs cleaved concomitantly a alpha and b beta-chains of fibrinogen. |
1994-10-27 |
2023-08-12 |
rat |
| R C Strunk, J A Fleischer, Y Katz, F S Col. Developmentally regulated effects of lipopolysaccharide on biosynthesis of the third component of complement and factor B in human fibroblasts and monocytes. Immunology. vol 82. issue 2. 1994-10-21. PMID:7927503. |
experiments with lps and cycloheximide or lps and interleukin-1 alpha (il-1 alpha) suggested that a newly synthesized protein did not participate in translational regulation and that lps induction did not alter translational activity of il-1 alpha-induced c3 and factor b transcripts. |
1994-10-21 |
2023-08-12 |
human |
| A Sahu, T R Kozel, M K Pangbur. Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation. The Biochemical journal. vol 302 ( Pt 2). 1994-10-14. PMID:8092994. |
human c4a and alpha 2-macroglobulin preferentially form amide linkages while human c3 primarily forms ester linkages with hydroxyl groups. |
1994-10-14 |
2023-08-12 |
human |
| C S Angel, M Ruzek, M K Hostette. Degradation of C3 by Streptococcus pneumoniae. The Journal of infectious diseases. vol 170. issue 3. 1994-10-06. PMID:8077717. |
after growth to exponential phase in todd-hewitt broth, clinical and laboratory isolates of streptococcus pneumoniae serotypes 3, 4, and 14 readily degraded first the beta and then the alpha chains of purified human c3 in the absence of serum or other complement proteins, as assessed by sds-page. |
1994-10-06 |
2023-08-12 |
human |