| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y B Ouyang, Y Tan, M Comb, C L Liu, M E Martone, B K Siesjö, B R H. Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 19. issue 10. 1999-10-29. PMID:10532637. |
western blot analysis showed that cyt c was increased in the cytosolic fraction in the hippocampus after 36 and 48 hours of reperfusion. |
1999-10-29 |
2023-08-12 |
rat |
| Y B Ouyang, Y Tan, M Comb, C L Liu, M E Martone, B K Siesjö, B R H. Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 19. issue 10. 1999-10-29. PMID:10532637. |
as demonstrated by western blot using phosphospecific akt antibody, phosphorylation of akt at serine-473 in the hippocampal region was highly increased during the first 24 hours but not at 48 hours of reperfusion. |
1999-10-29 |
2023-08-12 |
rat |
| E Nagata, K Tanaka, S Suzuki, T Dembo, Y Fukuuchi, A Futatsugi, K Mikoshib. Selective inhibition of inositol 1,4,5-triphosphate-induced Ca2+ release in the CA1 region of the hippocampus in the ischemic gerbil. Neuroscience. vol 93. issue 3. 1999-10-21. PMID:10473264. |
in severely ischemic gerbils, immunohistochemical analysis of the hippocampus showed loss of type 1 inositol 1,4,5-trisphosphate receptor protein with preservation of immunoreactivity for type 2 and 3 inositol 1,4,5-trisphosphate receptor proteins, which was confirmed by western blot analysis. |
1999-10-21 |
2023-08-12 |
Not clear |
| S Chen, X Huang, X J Zeng, W Sieghart, E I Tiet. Benzodiazepine-mediated regulation of alpha1, alpha2, beta1-3 and gamma2 GABA(A) receptor subunit proteins in the rat brain hippocampus and cortex. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430468. |
quantitative western blot analysis showed that beta3 subunit protein levels in crude homogenates of the hippocampal dentate region from flurazepam-treated rats, an area which showed fairly uniform decreases in beta3 subunit immunostaining (16-21%), were reduced to a similar degree (18%). |
1999-10-08 |
2023-08-12 |
rat |
| A Miyake, S Mochizuki, H Yokoi, M Kohda, K Furuich. New ether-à-go-go K(+) channel family members localized in human telencephalon. The Journal of biological chemistry. vol 274. issue 35. 1999-09-30. PMID:10455180. |
northern blot analysis indicates that bec1 is exclusively expressed in human brain, where the expression is concentrated in the telencephalic areas such as the cerebral cortex, amygdala, hippocampus, and striatum. |
1999-09-30 |
2023-08-12 |
human |
| L Shao, J R Ciallella, H Q Yan, X Ma, B M Wolfson, D W Marion, S T Dekosky, C E Dixo. Differential effects of traumatic brain injury on vesicular acetylcholine transporter and M2 muscarinic receptor mRNA and protein in rat. Journal of neurotrauma. vol 16. issue 7. 1999-09-24. PMID:10447068. |
semiquantitative measurements of vacht and m2 protein in hippocampal homogenates from injured and sham rats were assessed with western blot analysis. |
1999-09-24 |
2023-08-12 |
rat |
| L Shao, J R Ciallella, H Q Yan, X Ma, B M Wolfson, D W Marion, S T Dekosky, C E Dixo. Differential effects of traumatic brain injury on vesicular acetylcholine transporter and M2 muscarinic receptor mRNA and protein in rat. Journal of neurotrauma. vol 16. issue 7. 1999-09-24. PMID:10447068. |
at 4 weeks after injury, both immunohistochemical and western blot methods demonstrated an increase in hippocampal vacht protein. |
1999-09-24 |
2023-08-12 |
rat |
| D Fan, S Y Grooms, R C Araneda, A B Johnson, K Dobrenis, J A Kessler, R S Zuki. AMPA receptor protein expression and function in astrocytes cultured from hippocampus. Journal of neuroscience research. vol 57. issue 4. 1999-09-09. PMID:10440906. |
by northern blot analysis, glur1 mrna was highest in astrocyte cultures from cerebellum and hippocampus and moderate in astrocyte cultures from neocortex and striatum. |
1999-09-09 |
2023-08-12 |
Not clear |
| L Kuschel, A Hansel, R Schönherr, H Weissbach, N Brot, T Hoshi, S H Heineman. Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA). FEBS letters. vol 456. issue 1. 1999-09-09. PMID:10452521. |
with dot blot analyses based on rna from human tissues, expression of hmsra was found in all tissues tested, with highest mrna levels in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. |
1999-09-09 |
2023-08-12 |
human |
| C M Anderson, S A Baldwin, J D Young, C E Cass, F E Parkinso. Distribution of mRNA encoding a nitrobenzylthioinosine-insensitive nucleoside transporter (ENT2) in rat brain. Brain research. Molecular brain research. vol 70. issue 2. 1999-09-08. PMID:10407178. |
the present study used rt-pcr, northern blot and in situ hybridization and detected rent2 transcript in several brain regions including hippocampus, cortex, striatum and cerebellum. |
1999-09-08 |
2023-08-12 |
human |
| S L Chan, W S Griffin, M P Mattso. Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. Journal of neuroscience research. vol 57. issue 3. 1999-09-08. PMID:10412022. |
western blot analyses using antibodies against different subunits of 2-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) and n-methyl-d-aspartate (nmda) types of ionotropic glutamate receptors indicate that ampa receptor subunits (glur1, glur2/3, and glur4), but not nmda receptor subunits (nr1 and nr2a), are proteolytically cleaved after exposure of hippocampal neurons to apoptotic insults, including abeta, and that the caspase inhibitor zvad-fmk suppresses such cleavage. |
1999-09-08 |
2023-08-12 |
Not clear |
| K A Kimura, J Chiu, J N Reynolds, J F Brie. Effect of chronic prenatal ethanol exposure on nitric oxide synthase I and III proteins in the hippocampus of the near-term fetal guinea pig. Neurotoxicology and teratology. vol 21. issue 3. 1999-08-24. PMID:10386828. |
the nos i and nos iii protein expression and localization in the hippocampus were determined using western blot analysis and immunohistochemistry, respectively. |
1999-08-24 |
2023-08-12 |
Not clear |
| F C Zhou, T D Patel, D Swartz, Y Xu, M R Kelle. Production and characterization of an anti-serotonin 1A receptor antibody which detects functional 5-HT1A binding sites. Brain research. Molecular brain research. vol 69. issue 2. 1999-08-03. PMID:10366740. |
western blot analysis indicated that the polyclonal anti-5-ht1a-m3i antibody accurately recognized the fusion protein expressed in bacteria and labeled a prominent 67 kda protein band in the hippocampus, cortex, brainstem, cerebellum and kidney with a density profile corresponding to the relative abundance of the 5-ht1a receptor in these tissues. |
1999-08-03 |
2023-08-12 |
rat |
| J Lu, M Karadsheh, E Delpir. Developmental regulation of the neuronal-specific isoform of K-Cl cotransporter KCC2 in postnatal rat brains. Journal of neurobiology. vol 39. issue 4. 1999-07-28. PMID:10380077. |
developmental up-regulation of kcc2 expression was demonstrated in the entire rat brain by northern and western blot analyses, and in the hippocampus by immunofluorescence. |
1999-07-28 |
2023-08-12 |
rat |
| J K Newcomb, B R Pike, X Zhao, N L Banik, R L Haye. Altered calpastatin protein levels following traumatic brain injury in rat. Journal of neurotrauma. vol 16. issue 1. 1999-07-22. PMID:9989462. |
western blot analyses of cast in cortex and hippocampus detected two bands corresponding to molecular weights of 130 kda [high-molecular-weight (hmw)] and 80 kda [low-molecular-weight (lmw)]. |
1999-07-22 |
2023-08-12 |
rat |
| W Matsunaga, S Miyata, Y Hashimoto, S H Lin, T Nakashima, T Kiyohara, T Matsumot. Microtubule-associated protein-2 in the hypothalamo-neurohypophysial system: low-molecular-weight microtubule-associated protein-2 in pituitary astrocytes. Neuroscience. vol 88. issue 4. 1999-07-15. PMID:10336137. |
western blot analysis revealed expression of high-molecular-weight microtubule-associated protein-2 in the whole brain, hippocampus and whole hypothalamus. |
1999-07-15 |
2023-08-12 |
rat |
| M Waragai, C H Lammers, S Takeuchi, I Imafuku, Y Udagawa, I Kanazawa, M Kawabata, M M Mouradian, H Okazaw. PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival. Human molecular genetics. vol 8. issue 6. 1999-07-08. PMID:10332029. |
northern blot and in situ hybridization analyses revealed that pqbp-1 is a ubiquitous protein and is expressed primarily in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. |
1999-07-08 |
2023-08-12 |
Not clear |
| M Y Lee, W K Ju, J H Cha, B C Son, M H Chun, J K Kang, C K Par. Expression of vascular endothelial growth factor mRNA following transient forebrain ischemia in rats. Neuroscience letters. vol 265. issue 2. 1999-06-29. PMID:10327180. |
northern blot analysis revealed that vegf mrna of the hippocampus was increased from 12 h after reperfusion, with a peak at 1 day. |
1999-06-29 |
2023-08-12 |
rat |
| G Bregola, S Candeletti, P Romualdi, M Simonat. Limbic seizures increase pronociceptin mRNA levels in the thalamic reticular nucleus. Neuroreport. vol 10. issue 3. 1999-06-10. PMID:10208586. |
northern blot analysis revealed increased pronociceptin mrna levels in the thalamus (but not in the hippocampus) 3-24 h after kainate administration, with maximal effect (2-fold increase over basal levels) reached at 6 h. no variation in pronociceptin mrna levels was observed 1-6 h after a stimulus-evoked kindled seizure. |
1999-06-10 |
2023-08-12 |
Not clear |
| G Y Ng, T McDonald, T Bonnert, M Rigby, R Heavens, P Whiting, A Chateauneuf, N Coulombe, S Kargman, T Caskey, J Evans, G P O'neill, Q Li. Cloning of a novel G-protein-coupled receptor GPR 51 resembling GABAB receptors expressed predominantly in nervous tissues and mapped proximal to the hereditary sensory neuropathy type 1 locus on chromosome 9. Genomics. vol 56. issue 3. 1999-05-24. PMID:10087195. |
northern blot analysis and in situ hybridization revealed that gpr 51 transcripts were predominantly expressed in the central nervous system with highest abundance in the cortex, thalamus, hippocampus, amygdala, cerebellum, and spinal cord. |
1999-05-24 |
2023-08-12 |
human |