| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| So Jeong Nam, You Jin Han, Wonpyo Lee, Bitna Kang, Min-Koo Choi, Yong-Hae Han, Im-Sook Son. Effect of Red Ginseng Extract on the Pharmacokinetics and Efficacy of Metformin in Streptozotocin-Induced Diabetic Rats. Pharmaceutics. vol 10. issue 3. 2020-10-01. PMID:29970815. |
biochemical parameters such as alanine aminotransferase (alt), aspartate aminotransferase (ast), triglycerides, total cholesterol, high-density lipoprotein (hdl) cholesterol, low-density lipoprotein (ldl) cholesterol levels were not different among the three treatment groups. |
2020-10-01 |
2023-08-13 |
rat |
| Mai O Kadry, Rehab M Abdel-Megeed, Emad El-Meliegy, Abdel-Hamid Z Abdel-Hami. Crosstalk between GSK-3, c-Fos, NFκB and TNF-α signaling pathways play an ambitious role in Chitosan Nanoparticles Cancer Therapy. Toxicology reports. vol 5. 2020-10-01. PMID:30013938. |
the results elucidated that den significantly increased serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2020-10-01 |
2023-08-13 |
rat |
| Ren-Wang Chen, Meng-Jun Qiu, Yaobing Chen, Tao Zhang, Xiao-Xiao He, Ying Li, Wen-Jia Sun, Tao Xie, Sheng-Li Yang, Jian-Li H. Analysis of the clinicopathological features and prognostic factors of primary hepatic neuroendocrine tumors. Oncology letters. vol 15. issue 6. 2020-10-01. PMID:30065788. |
single-factor analysis showed that carbohydrate antigen 125 (ca125), alanine aminotransferase (alt), aspartate aminotransferase (ast), hemoglobin (hb), ki-67 positive index (pi), surgical treatment and pathological grading were correlated to phnet prognosis (p<0.05); multifactor analysis revealed that ki-67 pi was associated with the prognosis (p<0.05). |
2020-10-01 |
2023-08-13 |
Not clear |
| Laura Bona, Nienke van Staaveren, Bishwo Bandhu Pokharel, Marinus van Krimpen, Alexandra Harlander-Matausche. The Effect of Low Protein Energy-Rich Diets on Plasma Hepatic Markers, Hepatic Damage, and Discrimination Reversal Learning in Young Female Chicks. Frontiers in veterinary science. vol 5. 2020-10-01. PMID:30177972. |
all chicks had post-mortem signs of hepatic hemorrhage/increased liver color scores and aspartate aminotransferase (ast) levels above 230 u/l indicative of hepatic damage in birds. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kyawzaw Lin, Aung Naing Lin, Sandar Linn, Pwint Phyu Hlaing, Viswanath Vasudevan, Madhavi Redd. Ginseng-Related Drug-Induced Liver Injury. Case reports in gastroenterology. vol 12. issue 2. 2020-10-01. PMID:30186097. |
liver function test showed aspartate transaminase (ast) 717 u/l, alanine transaminase (alt) 343 u/l, total bilirubin 5 mg/dl, direct bilirubin 3.3 mg/dl, alkaline phosphatase 182 u/l, with international normalized ratio (inr) 1.2. |
2020-10-01 |
2023-08-13 |
Not clear |
| Lei Luo, Zhang Zhou, Juan Xue, Yao Wang, Juan Zhang, Xin Cai, Yuqing Liu, Fan Yan. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186392. |
elisa kits were used to measure the endotoxin, alanine transaminase (alt) and aspartate transaminase (ast) levels in the portal vein, while interleukin (il)-6 and tumor necrosis factor (tnf)-α expression in the ileal tissue was measured. |
2020-10-01 |
2023-08-13 |
rat |
| Xiang Dong, Hongmei Yang, Cong Li, Qi Liu, Qinglin Bai, Zhaoran Zhan. Triiodothyronine alleviates alcoholic liver disease injury through the negative regulation of the NLRP3 signaling pathway. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186412. |
alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bilirubin (tbil) levels were determined and morphological changes in the liver tissues were observed under the optical microscope. |
2020-10-01 |
2023-08-13 |
mouse |
| Qian Zhao, Qian Xiao, Xiangying Meng, Jianyang Chen, Weiwei Ye, Yong Zho. Effect of saxagliptin on the expression of HIF-1α in the liver of diabetic rats with fatty liver. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186489. |
levels of total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), aspartate aminotransferase (ast), alanine aminotransferase (alt) and γ-glutamyl transferase (ggt) in model and treatment group were significantly higher than those in control group (p<0.05), but were significantly reduced with the prolonged treatment (p<0.05). |
2020-10-01 |
2023-08-13 |
rat |
| Lijun Zhao, Xiaoqiang Zhu, Renhuai Cong, Xiangliang Yang, Yanhong Zh. The Protective Effects of Danggui-Baizhu-Tang on High-Fat Diet-Induced Obesity in Mice by Activating Thermogenesis. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30258363. |
it was indicated that concentration of triacylglycerol (tg), total cholesterol (tc), alanine aminotransferase (alt), aspartate aminotransferase (ast) in serum were reduced strikingly, as well as accumulation of lipid droplets in liver. |
2020-10-01 |
2023-08-13 |
mouse |
| Tian Hu, Jincheng Li, Chuhong Zhang, Xiu Lv, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zu. The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma. Genes & diseases. vol 4. issue 2. 2020-10-01. PMID:30258914. |
the expression of mir-4463 in the serum of hcc patients was significantly higher than that in control group (p < 0.05), and the expression level was independent of gender, tumor size, cell types, stages, alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbil) and hbsag status (p > 0.05). |
2020-10-01 |
2023-08-13 |
Not clear |
| Maedeh Hamzeh, Seyed Jalal Hosseinimehr, Ali Reza Khalatbary, Hamid Reza Mohammadi, Ayat Dashti, Fereshteh Talebpour Amir. Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model. Research in pharmaceutical sciences. vol 13. issue 5. 2020-10-01. PMID:30271446. |
the biochemical results showed that administration of cp increased hepatic biomarkers enzymes as aspartate aminotransferase (ast), alanine aminotransferase (alt) and lactate dehydrogenase (ldh) levels. |
2020-10-01 |
2023-08-13 |
rat |
| Emily A Minor, Mackenzie S Newman, Justin T Kupe. Chronic, Recreational Chloroform-Induced Liver Injury. Case reports in hepatology. vol 2018. 2020-10-01. PMID:30275992. |
an extensive work-up revealed an aspartate aminotransferase (ast) of 13,527 u/l and alanine aminotransferase (alt) of 8,745 u/l, but the cause of his liver injury could not be determined. |
2020-10-01 |
2023-08-13 |
Not clear |
| Taseen Syed, Javid Fazili, Ijlal Akbar Ali, Daniel Zhao, Diane Hughes, Sultan Mahmoo. Hepatocellular Carcinoma Occurrence and Recurrence in Hepatitis C-infected Patients Treated with Direct-acting Antivirals. Cureus. vol 10. issue 6. 2020-10-01. PMID:30280052. |
we further subdivided these patients into those who eventually were diagnosed with hcc (group 1) and those who were not (group 2). these subgroups were comparable in regards to race, gender, baseline serum aspartate aminotransferase (ast), alanine aminotransferase (alt), platelets, sodium, hcv genotypes, and pretreatment viral load. all patients completed therapy. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sinem Ilgin, Volkan Kilic, Merve Baysal, Gozde Aydogan-Kilic, Seyda Ucarcan, Begum Dermenci, Ozlem Atl. Evidence for cardiotoxicity associated with sertraline in rats. Toxicology research. vol 7. issue 5. 2020-10-01. PMID:30310659. |
in the study reported here we aimed to identify the cardiotoxic effects of sertraline by evaluating serum cardiac biomarkers, such as serum aspartate aminotransferase (ast), creatinine phosphokinase-myoglobin band (ck-mb), lactate dehydrogenase (ldh), and cardiac troponin t (ctn-t) levels as well as electrocardiographic parameters, dna damage in cardiomyocytes, and histological findings of heart tissue in rats that were administered oral doses of 5, 10, or 20 mg kg |
2020-10-01 |
2023-08-13 |
rat |
| Lenche Kostadinova, Carey L Shive, Elizabeth Zebrowski, Brianna Fuller, Kelsey Rife, Amy Hirsch, Anita Compan, Anita Moreland, Yngve Falck-Ytter, Daniel L Popkin, Donald D Anthon. Soluble Markers of Immune Activation Differentially Normalize and Selectively Associate with Improvement in AST, ALT, Albumin, and Transient Elastography During IFN-Free HCV Therapy. Pathogens & immunity. vol 3. issue 1. 2020-10-01. PMID:30370392. |
during chronic hepatitis c virus (hcv) infection, aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels mark active liver inflammation and tissue damage, while albumin reflects synthetic liver function and nutritional status. |
2020-10-01 |
2023-08-13 |
Not clear |
| Matthias Steininger, Max-Paul Winter, Thomas Reiberger, Lorenz Koller, Feras El-Hamid, Stefan Forster, Sebastian Schnaubelt, Christian Hengstenberg, Klaus Distelmaier, Georg Goliasch, Johann Wojta, Aurel Toma, Alexander Niessner, Patrick Sulzgrube. De-Ritis Ratio Improves Long-Term Risk Prediction after Acute Myocardial Infarction. Journal of clinical medicine. vol 7. issue 12. 2020-10-01. PMID:30477196. |
recent evidence suggested levels of aspartate aminotransferase (ast), alanine transaminase (alt), and ast/alt ratio (de-ritis ratio) were associated with a worse outcome after acute myocardial infarction (ami). |
2020-10-01 |
2023-08-13 |
Not clear |
| Mir Hilal Ahmad, Mahino Fatima, Mobarak Hossain, Amal Chandra Monda. Evaluation of naproxen-induced oxidative stress, hepatotoxicity and Journal of pharmaceutical analysis. vol 8. issue 6. 2020-10-01. PMID:30595947. |
the aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp) activities, and total bilirubin (tbil) levels were measured in the liver tissues. |
2020-10-01 |
2023-08-13 |
rat |
| Yuanyuan Xiao, Ming Zeng, Lirong Yin, Na Li, Fang Xia. Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes. Toxicology research. vol 8. issue 1. 2020-10-01. PMID:30713657. |
in the present study, we demonstrate cr(vi) targeted mitochondrial respiratory chain complex i (mrcc i) activity and induced reactive oxygen species (ros) accumulation, which caused mitochondrial damage that was characterized by the increase of permeability transition pore (ptp) open rate, the collapse of mitochondrial membrane potential (mmp), and the release of apoptosis-inducing factor (aif) and cytochrome c (cyt c) from mitochondria to cytoplasm, which then induced cell viability loss and increased aspartate transaminase (ast)/alanine transaminase (alt) leakage. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bihui Liu, Yuan Fang, Ruokun Yi, Xin Zha. Preventive Effect of Blueberry Extract on Liver Injury Induced by Carbon Tetrachloride in Mice. Foods (Basel, Switzerland). vol 8. issue 2. 2020-10-01. PMID:30717106. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) are important clinical liver function indicators; the changes of triglyceride (tg) and total cholesterol (tc) are observed after liver injury; interleukin-6 (il-6), tumour necrosis factor-α (tnf-α) and interferon-γ (ifn-γ) are important inflammatory indexes; superoxide dismutase (sod) activity and thiobarbituric acid reactive substances (tbars) are important changes of oxidative stress indexes. |
2020-10-01 |
2023-08-13 |
mouse |
| Hiromi Higaki, Morikazu Onji, Satoshi Takeji, Takahide Uehara, Keitaro Kawasaki, Youhei Kashimoto, Takatoshi Murakami, Tomotaka Yamaguchi, Jiro Miyaike, Masaki Oomoto, Masanori Ab. A Case of Severe Drug-induced Liver Injury Caused by Over the Counter Herb (Cinnamon): Review of Literature. Euroasian journal of hepato-gastroenterology. vol 8. issue 2. 2020-10-01. PMID:30828560. |
prothrombin time activation (pt) was 45%, aspartate transaminase (ast) was 1104 iu/l, and total bilirubin (t-bil) 14.7 mg/dl. |
2020-10-01 |
2023-08-13 |
Not clear |