| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Li, Chunyang Li, Jian Wang, Chuanwu Zhu, Li Zhu, Fang Ji, Longgen Liu, Tianmin Xu, Biao Zhang, Leyang Xue, Xiaomin Yan, Rui Huang, Chao Wu, Xuebing Ya. A case series of COVID-19 patients with chronic hepatitis B virus infection. Journal of medical virology. vol 92. issue 11. 2020-12-24. PMID:32558945. |
on admission, 1 (14.3%) patient had mildly elevated alanine aminotransferase (alt) level (>40 u/l) and 1 (14.3%) had elevated aspartate aminotransferase (ast) level (>40 u/l). |
2020-12-24 |
2023-08-13 |
Not clear |
| Anna M Kosyreva, Dzhuliia Sh Dzhalilova, Olga V Makarova, Ivan S Tsvetkov, Natalia A Zolotova, Marina A Diatroptova, Elena A Ponomarenko, Vladimir A Mkhitarov, Dmitriy N Khochanskiy, Liliya P Mikhailov. Sex differences of inflammatory and immune response in pups of Wistar rats with SIRS. Scientific reports. vol 10. issue 1. 2020-12-24. PMID:32985516. |
males demonstrate the increasing neopterin, corticosterone levels and alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity. |
2020-12-24 |
2023-08-13 |
rat |
| K E Ying-Mei, Jiang Min, Zhou Shu-Bo, Y U Hong, Wang Juan, G E Fen. [Component analysis of Ophiocordyceps lanpingensis polysaccharides and study on alleviation of hepatic fibrosis in mice by polysaccharides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 21. 2020-12-23. PMID:33350243. |
based on the hepatic fibrosis model induced by ccl_4 in mice, olp could significantly relieve the inflammation and fibrosis levels of hepatic tissues, reverse the ccl_4-induced increasing levels of alanine aminotransferase(alt) and aspartate aminotransferase(ast) in mice serum, and recover the functions of liver to a normal state. |
2020-12-23 |
2023-08-13 |
mouse |
| L I Yan-Xi, L I Xiao-Peng, G U Jian, L I Jia-Chuan, Gong Pu-Yang, Shi Zhi-Long, M A Q. [Study on protective mechanism of Tibetan medicine Ershiwuwei Songshi Pills on cholestatic liver injury in rats based on FXR signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 21. 2020-12-23. PMID:33350245. |
serum alkaline phosphatase(alp), alanine aminotransferase(alt), aspartate aminotransferase(ast), direct bilirubin(dbil), total bilirubin(tbil), and total bile acid(tba) levels were detected, and liver histopathological changes were observed. |
2020-12-23 |
2023-08-13 |
rat |
| Kenta Mizoi, Mayu Hosono, Hajime Kojima, Takuo Ogihar. Establishment of a primary human hepatocyte spheroid system for evaluating metabolic toxicity using dacarbazine under conditions of CYP1A2 induction. Drug metabolism and pharmacokinetics. vol 35. issue 2. 2020-12-22. PMID:32037158. |
albumin secretion, urea secretion, and aspartate aminotransferase (ast) leakage. |
2020-12-22 |
2023-08-13 |
human |
| Tingting Zhao, Changping Zhai, Hongmei Song, Yanhai Wu, Chuanhui Ge, Yonglin Zhang, Hongxia Xu, Zhengsuo Chi, Hui Chu, Wei Shi, Xiaodong Cheng, Xin Li, Mengdi Ma, Mengyuan Xu, Jiaqi Hu, Ya Xie, Yanan Lin, Hongxu Chen, Yiting Li, Dongliang Jia. Methamphetamine-Induced Cognitive Deficits and Psychiatric Symptoms Are Associated with Serum Markers of Liver Damage. Neurotoxicity research. vol 37. issue 1. 2020-12-21. PMID:31691188. |
liver function was assessed by serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total protein, albumin, globulin, apolipoprotein b (apob), triglyceride, total cholesterol, and glucose concentrations in 106 ma addicts and 76 controls. |
2020-12-21 |
2023-08-13 |
human |
| Huifang Zhang, Rui Liu, Qun L. Separation and Characterization of Phenolamines and Flavonoids from Rape Bee Pollen, and Comparison of Their Antioxidant Activities and Protective Effects Against Oxidative Stress. Molecules (Basel, Switzerland). vol 25. issue 6. 2020-12-21. PMID:32168811. |
furthermore, phenolamines could significantly reduce the reactive oxygen species (ros), alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, and increase the superoxide dismutase (sod) and glutathione (gsh) levels. |
2020-12-21 |
2023-08-13 |
bee |
| Chang-Hong Cheng, Hong-Ling Ma, Yi-Qin Deng, Juan Feng, Yu-Kun Jie, Zhi-Xun Gu. Oxidative stress, cell cycle arrest, DNA damage and apoptosis in the mud crab (Scylla paramamosain) induced by cadmium exposure. Chemosphere. vol 263. 2020-12-21. PMID:33297221. |
aspartate aminotransferase (ast), alanine aminotransferase (alt) and lactate dehydrogenase (ldh) activity significantly increased after cadmium exposure. |
2020-12-21 |
2023-08-13 |
cat |
| Zhi-Hua Li, Ping L. Effects of the tributyltin on the blood parameters, immune responses and thyroid hormone system in zebrafish. Environmental pollution (Barking, Essex : 1987). vol 268. issue Pt A. 2020-12-18. PMID:33007597. |
the effects of long-term exposure to tbt on blood parameters (nh3, ammonia; glu, glucose; tp, total proteins; ck, creatine kinase; alt, alanine aminotransferase; ast, aspartate aminotransferase), immune responses (lys, lysozyme; igm, immunoglobulin m) and some indexes related thyroid hormone system (t3, 3,5,3'-triiodothyronine; t4, thyroxine) were measured in zebrafish, as well as the expression of genes related to immune responses and thyroid hormone system. |
2020-12-18 |
2023-08-13 |
zebrafish |
| Meryem Sayan, Derya Karabulut, Saim Özdama. Assessment of the protective and therapeutic effect of melatonin against thioacetamide-induced acute liver damage. Journal of biochemical and molecular toxicology. vol 34. issue 4. 2020-12-16. PMID:31967703. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp) levels in blood serum samples and transforming growth factor-β (tgf-β) and tumor necrosis factor-α (tnf-α) levels were determined in liver tissue. |
2020-12-16 |
2023-08-13 |
rat |
| Yalan Dong, Haifeng Zhou, Mingyue Li, Zili Zhang, Weina Guo, Ting Yu, Yang Gui, Quansheng Wang, Lei Zhao, Shanshan Luo, Heng Fan, Desheng H. A novel simple scoring model for predicting severity of patients with SARS-CoV-2 infection. Transboundary and emerging diseases. vol 67. issue 6. 2020-12-16. PMID:32469137. |
we found that an increased level of white blood cells (wbc), neutrophils, d-dimer, fibrinogen (fib), il-6, c-reactive protein (crp), erythrocyte sedimentation rate (esr), alanine aminotransferase (alt), aspartate aminotransferase (ast), α-hydroxybutyrate dehydrogenase (hbdh), serum amyloid a (saa) and a decreased level of lymphocytes were important risk factors associated with severity. |
2020-12-16 |
2023-08-13 |
Not clear |
| Weiqiang Ju, Zhitao Chen, Qiang Zhao, Yixi Zhang, Changjun Huang, Linhe Wang, Caihui Zhu, Yinghua Chen, Zhiyong Guo, Maogen Chen, Xiaoshun H. Non-re-cooling implantation of marginal liver graft after machine perfusion: report of a case. Annals of translational medicine. vol 8. issue 21. 2020-12-16. PMID:33313210. |
the highest levels of alanine transaminase (alt) and aspartate transaminase (ast) after surgery were 235 and 1,076 u/l, respectively, on the first postoperative day (pod). |
2020-12-16 |
2023-08-13 |
Not clear |
| Gjin Ndrepepa, Stefan Holdenrieder, Salvatore Cassese, Erion Xhepa, Massimiliano Fusaro, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrat. Aspartate aminotransferase and mortality in patients with ischemic heart disease. Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 30. issue 12. 2020-12-14. PMID:32917497. |
evidence on the association between aspartate aminotransferase (ast) activity and mortality of patients with ischemic heart disease (ihd) is limited. |
2020-12-14 |
2023-08-13 |
Not clear |
| Sung-Eun Lee, Hong Koh, Dong Jin Joo, Balachandar Nedumaran, Hwang-Ju Jeon, Chul-Seung Park, Robert A Harris, Yong Deuk Ki. Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway. Journal of pineal research. vol 68. issue 3. 2020-12-07. PMID:32053237. |
levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), hepatic cyp2e1 protein, and reactive oxygen species (ros) were elevated in alcohol-fed wt mice but not in cb1r antagonist-treated, crbn null, or yy1-silenced mice. |
2020-12-07 |
2023-08-13 |
mouse |
| Geum-Hwa Lee, Cheng Peng, Seon-Ah Park, The-Hiep Hoang, Hwa-Young Lee, Junghyun Kim, Seong-Il Kang, Chi-Heon Lee, Joo-Sang Lee, Han-Jung Cha. Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling. Nutrients. vol 12. issue 3. 2020-12-07. PMID:32121602. |
the high-fat diet (hfd)-fed rats showed significant increase in total cholesterol, alanine aminotransferase (alt), triglycerides, aspartate aminotransferase (ast), and lipid peroxidation compared to the normal chow-diet (ncd) group rats; but cpew and cpef limited this effect. |
2020-12-07 |
2023-08-13 |
rat |
| Anwar E Ahmed, Bassam Dahman, Asmaa Altamimi, Donna K McClish, Hamdan Al-Jahdal. The aspartate aminotransferase/platelet count ratio index as a marker of dengue virus infection: Course of illness. Journal of infection and public health. vol 13. issue 7. 2020-12-07. PMID:32265161. |
the usefulness of laboratory tests in the decision-making process with regard to early identification of dengue virus infection has not been widely reported, particularly the aspartate aminotransferase (ast)/platelet count ratio index during a patient's days of illness. |
2020-12-07 |
2023-08-13 |
Not clear |
| Vahideh Behrouz, Naheed Aryaeian, Mohammad Javad Zahedi, Shima Jazayer. Effects of probiotic and prebiotic supplementation on metabolic parameters, liver aminotransferases, and systemic inflammation in nonalcoholic fatty liver disease: A randomized clinical trial. Journal of food science. vol 85. issue 10. 2020-12-07. PMID:32885440. |
probiotic supplementation was able to decrease triglyceride, alanine aminotransferase (alt), aspartate aminotransferase (ast), γ-glutamyltransferase (ggt), and alkaline phosphatase compared to control group. |
2020-12-07 |
2023-08-13 |
human |
| Chia-Hao Chang, Zong-Zheng Liu, Tsung-Han Le. Changes in hypothermal stress-induced hepatic mitochondrial metabolic patterns between fresh water- and seawater-acclimated milkfish, Chanos chanos. Scientific reports. vol 9. issue 1. 2020-12-04. PMID:31811227. |
therefore, the activities of the enzymes involved in mitochondrial amino acid biosynthesis (aspartate aminotransferase (ast) and glutamate dehydrogenase (gdh)) were evaluated to elucidate energy flow in milkfish livers under hypothermal stress. |
2020-12-04 |
2023-08-13 |
Not clear |
| Rui-Bo Jia, Juan Wu, Zhao-Rong Li, Zhi-Rong Ou, Qiyuan Zhu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Comparison of physicochemical properties and antidiabetic effects of polysaccharides extracted from three seaweed species. International journal of biological macromolecules. vol 149. 2020-12-04. PMID:31945436. |
the analysis of body weight, water intake, fasting blood glucose, insulin, oral glucose tolerance, blood lipid indicators (including total cholesterol (tc), triglyceride (tg), low density lipoprotein cholesterol (ldl-c) and free fatty acid (ffa)), liver function indexes (involving alanine aminotransferase (alt) and aspartate aminotransferase (ast)) and renal function profiles (comprising uric acid (ua) and urea nitrogen (bun)) showed that aps possessed obvious antidiabetic activities, and fvp showed better effects in controlling the levels of ffa, ast, alt, ua and bun. |
2020-12-04 |
2023-08-13 |
rat |
| Chengxiao Wang, Luoyao Zheng, Shengnan Liu, Xiaoxi Guo, Yuan Qu, Mingju Gao, Xiuming Cui, Ye Yan. A novel acidic polysaccharide from the residue of Panax notoginseng and its hepatoprotective effect on alcoholic liver damage in mice. International journal of biological macromolecules. vol 149. 2020-12-04. PMID:32035151. |
after administration of pnps-0.5 m, the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), and hepatic malondialdehyde (mda) were reduced to normal. |
2020-12-04 |
2023-08-13 |
mouse |