| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yujun Liu, Yuan Gao, Fenglian Ma, Mengying Sun, Guangqing Mu, Yanfeng Tu. The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet. Food & function. vol 11. issue 6. 2021-05-25. PMID:32530448. |
oral administration of l. plantarum y44 regulated lipid metabolism disorder by inhibiting the expression of fatty acid synthase (fas) and acetyl-coa carboxylase (acc) in the liver of obese mice, reducing the contents of total cholesterol (tc), triacylglycerols (tg), low density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt), and aspartate transaminase (ast) and increasing the content of high-density lipoprotein cholesterol (hdl-c) in the serum of obese mice. |
2021-05-25 |
2023-08-13 |
mouse |
| Chenchen Yu, Xixi Cai, Xuejiao Liu, Jianlong Liu, Na Zh. Betulin Alleviates Myocardial Ischemia-Reperfusion Injury in Rats via Regulating the Siti1/NLRP3/NF-κB Signaling Pathway. Inflammation. vol 44. issue 3. 2021-05-24. PMID:33392937. |
to study the effects of betulin (be) on myocardial ischemia-reperfusion (i/r) injury in rats, electrocardiogram (ecg) was detected by an electrocardiograph; myocardial infarction was evaluated by triphenyltetrazolium (ttc) staining, serum biochemical indicators myocardial enzymes creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), serum superoxide dismutase (sod), glutathione (gsh), nitric oxide (no), and malondialdehyde (mda); and inflammatory cytokines were tested by using commercial kits. |
2021-05-24 |
2023-08-13 |
rat |
| Ling Zhou, Xinlu Yang, Shuhua Shu, Sheng Wang, Fenglin Guo, Ying Yin, Weide Zhou, Han Han, Xiaoqing Cha. Sufentanil Protects the Liver from Ischemia/Reperfusion-Induced Inflammation and Apoptosis by Inhibiting ATF4-Induced TP53BP2 Expression. Inflammation. vol 44. issue 3. 2021-05-24. PMID:33751357. |
following pretreatment with sufentanil, the enzymatic activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in rat serum and the changes of hepatic histopathology were evaluated to track the extent of liver injury. |
2021-05-24 |
2023-08-13 |
rat |
| Teng Zhu, Qinqin Han, Xiaoxiao Zhang, Qiuzhong Ho. Effects of Xinnaoning combined with trimetazidine on the levels of CK and its isoenzymes, AST, ALT and LDH in patients with myocardial ischemia. American journal of translational research. vol 13. issue 4. 2021-05-23. PMID:34017451. |
to explore the effect of combin3e uw3 of xinnaoning and trimetazidine on the levels of creatine kinase (ck) and its isoenzymes (ck-mb), aspartate aminotransferase (ast), alanine aminotransferase (alt), and lactate dehydrogenase (ldh) in patients with myocardial ischemia (mi). |
2021-05-23 |
2023-08-13 |
Not clear |
| Kitson Deane, Ajay Singh, Azza Sarfraz, Zouina Sarfraz, Lyam Ciccone, Beishi Zheng, Arslan Afzal, Gulam Khan, Giovanna Rodriguez, Gul Bahtiya. Correlation of Severity of COVID-19 Disease With Gastrointestinal Manifestations and Liver Injury - A North Brooklyn Community Hospital Experience: A Retrospective Cohort Study. Cureus. vol 13. issue 4. 2021-05-23. PMID:34017658. |
conclusion elevated liver transaminases including alanine transaminase (alt) and aspartate transaminase (ast) at the time of hospital admission can predict critical care requirement and all-cause 30-day hospital mortality in patients with covid-19 infection. |
2021-05-23 |
2023-08-13 |
Not clear |
| Xinyu Toh, Jasmine Ong, Cathy Chan, Xuan Hui Teo, Steffie Toh, Charlene Judith Fernandez, Taoqi Huangf. First detection of rabbit haemorrhagic disease virus (RHDV2) in Singapore. Transboundary and emerging diseases. 2021-05-22. PMID:33892517. |
clinical pathology consistently reflected markedly elevated alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alkp). |
2021-05-22 |
2023-08-13 |
rabbit |
| Ting-Ting Zou, Yu Zhu, Chao-Min Wan, Qiong Lia. Clinical features of sodium-taurocholate cotransporting polypeptide deficiency in pediatric patients: case series and literature review. Translational pediatrics. vol 10. issue 4. 2021-05-22. PMID:34012853. |
hypercholanemia was documented in 12/12 (100%), elevated aspartate aminotransferase (ast) in 6/12 (50%), and elevated alanine aminotransferase (alt) in 1/12 (8.3%). |
2021-05-22 |
2023-08-13 |
human |
| Ann Abd-Almonem Farid, Nermin Abd-Almaksoud Afify, Aml Abd-Alhamid Alsharnoby, Eman Abdelsameea, Hanan M Bedai. Predictive Role of AURKA rs 1047972 Gene Polymorphism and the Risk of Development of Hepatocellular Carcinoma. Immunological investigations. 2021-05-21. PMID:34018460. |
afp: alpha-fetoprotein; alp: alkaline phosphatase; alt: alanine aminotransferase; ast: aspartate aminotransferase; aurka: aurora kinase a; bclc: barcelona- clinic liver cancer; cbc: complete blood count; ct: computed tomography; dm: diabetes mellitus; dna: deoxyribonucleic acid; edta: ethylene diamine tetraacetic acid; ggt: gamma-glutamyl transferase; hb: hemoglobin; hbv: hepatitis b virus; hbsag: hepatitis b surface antigen; hcc: hepatocellular carcinoma; hcv: hepatitis c virus; inr: international normalized ratio; mrna: messenger ribonucleic acid; or: odds ratio; pvt: portal vein thrombosis; rt-pcr: real-time polymerase chain reaction; snp: single nucleotide polymorphism; wbcs: white blood cells. |
2021-05-21 |
2023-08-13 |
Not clear |
| Qi Wang, Wen Xie, Ligai Liu, Peng Wang, Calvin Q Pa. Serum markers for predicting advanced fibrosis in patients with chronic hepatitis B and nonalcoholic fatty liver disease. Medicine. vol 100. issue 18. 2021-05-20. PMID:33950921. |
receiver operating characteristic curve (roc) analysis helped assess the accuracy of each marker.in patients with both diseases, 12.96% (7/54) had advanced fibrosis on biopsy and aspartate aminotransferase (ast) to platelet ratio index was the best performing marker for predicting advanced fibrosis. |
2021-05-20 |
2023-08-13 |
Not clear |
| Fu-Juan Jia, Zhuo Han, Jia-Hui Ma, Shi-Qing Jiang, Xing-Ming Zhao, Hang Ruan, Wei-Dong Xie, Xia L. Involvement of Reactive Oxygen Species in the Hepatorenal Toxicity of Actinomycin V In Vitro and In Vivo. Marine drugs. vol 18. issue 8. 2021-05-18. PMID:32824227. |
notably, act v caused less damage to both the liver and kidney than act d in vivo, indicated by organ to body weight ratios, as well as alanine aminotransferase (alt), aspartate aminotransferase (ast), and serum creatinine (scr) levels. |
2021-05-18 |
2023-08-13 |
human |
| Wen Nie, Kai Zhou, Ying Wang, Zhao-Ming Wang, Yong Xie, Hui Zhou, Bao-Cai X. Isolation and identification of bioactive peptides from Xuanwei ham that rescue oxidative stress damage induced by alcohol in HHL-5 hepatocytes. Food & function. vol 11. issue 11. 2021-05-18. PMID:33057513. |
alcohol-treated hhl-5 human hepatocytes were utilized as the alcohol-induced hepatocyte damage model to evaluate the effects of xhp on amounts of aminotransferase (alt), aspartate aminotransferase (ast) and malondialdehyde (mda). |
2021-05-18 |
2023-08-13 |
human |
| Lin-Lin Zhang, Xin-Yan Zhang, Yuan-Yuan Lu, Yi-Dan Bi, Xing-Lou Liu, Feng Fan. The Role of Autophagy in Murine Cytomegalovirus Hepatitis. Viral immunology. vol 34. issue 4. 2021-05-18. PMID:33566740. |
compared with the untreated infected group, increased transcription level of mcmv glycoprotein b (gb), increased expression levels of interleukin1-β (il-1β), aspartate aminotransferase (ast) and alanine aminotransferase (alt), decreased expression level of type i interferon α (ifn-α), as well as aggravated liver pathological injury were detected in starvation-treated infected group on days 3 and 7 p.i. |
2021-05-18 |
2023-08-13 |
mouse |
| Małgorzata Maśko, Małgorzata Domino, Tomasz Jasiński, Olga Witkowska-Piłaszewic. The Physical Activity-Dependent Hematological and Biochemical Changes in School Horses in Comparison to Blood Profiles in Endurance and Race Horses. Animals : an open access journal from MDPI. vol 11. issue 4. 2021-05-18. PMID:33920044. |
the hemogram parameters, creatine phosphokinase (cpk), aspartate aminotransferase (ast), blood lactate (lac), and total serum protein (tsp) concentrations were measured using the same protocol and equipment. |
2021-05-18 |
2023-08-13 |
Not clear |
| Mohamed A Hashem, Noura A Abd-Allah, Essam A Mahmoud, Shimaa A Amer, Mohamed Alkafaf. A Preliminary Study on the Effect of Psyllium Husk Ethanolic Extract on Hyperlipidemia, Hyperglycemia, and Oxidative Stress Induced by Triton X-100 Injection in Rats. Biology. vol 10. issue 4. 2021-05-18. PMID:33923513. |
phee administration alleviated the negative impact of triton on the serum levels of glucose, insulin, glycated hemoglobin (hba1c), homeostatic model assessment for insulin resistance (homa ir index), leptin hormone, alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transferase (ggt) and proteinogram. |
2021-05-18 |
2023-08-13 |
rat |
| Liping Cao, Zhenghong Li, Yi Ren, Mengmeng Wang, Zhizhou Yang, Wei Zhang, Xiaoqin Han, Mengya Yao, Zhaorui Sun, Shinan Ni. Xuebijing Protects Against Septic Acute Liver Injury Based on Regulation of GSK-3β Pathway. Frontiers in pharmacology. vol 12. 2021-05-18. PMID:33995024. |
results showed that xbj pretreatment reduced liver/body weight, aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities in serum, and inhibited levels of pro-inflammatory factors in serum. |
2021-05-18 |
2023-08-13 |
mouse |
| Tayyaba Bukhari, Lena Jafri, Hafsa Majid, Aysha Habib H Khan, Imran Siddiqu. Determining Bone Turnover Status in Patients With Chronic Liver Disease. Cureus. vol 13. issue 4. 2021-05-18. PMID:33996337. |
aspartate aminotransferase (ast), alanine transaminase (alt), albumin, and bilirubin, along with clinical signs of liver disease chronicity, were noted. |
2021-05-18 |
2023-08-13 |
Not clear |
| Rui-Bo Jia, Zhao-Rong Li, Zhi-Rong Ou, Juan Wu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Physicochemical Characterization of Hizikia fusiforme Polysaccharide and Its Hypoglycemic Activity via Mediating Insulin-Stimulated Blood Glucose Utilization of Skeletal Muscle in Type 2 Diabetic Rats. Chemistry & biodiversity. vol 17. issue 10. 2021-05-17. PMID:32955163. |
hfp administration at 400 mg/kg body weight/day displayed greater advantages than metformin in controlling the levels of fasting blood glucose, triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bile acid (tba) of diabetic rats. |
2021-05-17 |
2023-08-13 |
rat |
| Renchao Dong, Xiaohui Wang, Lu Wang, Changyuan Wang, Kai Huang, Ting Fu, Kexin Liu, Jingjing Wu, Huijun Sun, Qiang Men. Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. European journal of pharmacology. vol 890. 2021-05-17. PMID:33068587. |
yan improved cell viabilities via cell count kit-8 (cck-8) methods and obviously reduced aspartate aminotransferase (ast), alanine aminotransferase (alt), total cholesterol (tc) and total triglyceride (tg) levels. |
2021-05-17 |
2023-08-13 |
Not clear |
| Li-Chun Chen, Shi-Yu Zhang, Yu Zi, Hui-Min Zhao, Hong-Yu Wang, Yue Zhan. Functional coix seed protein hydrolysates as a novel agent with potential hepatoprotective effect. Food & function. vol 11. issue 11. 2021-05-17. PMID:33078805. |
cpp could significantly improve the alcohol metabolism in liver as evidenced by the enhanced activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2021-05-17 |
2023-08-13 |
mouse |
| Amany Behairy, Wafaa A M Mohamed, Lamiaa L M Ebraheim, Mohamed Mohamed Soliman, Yasmina M Abd-Elhakim, Nabela I El-Sharkawy, Taghred M Saber, Maha M El Dei. Boldenone Undecylenate-Mediated Hepatorenal Impairment by Oxidative Damage and Dysregulation of Heat Shock Protein 90 and Androgen Receptors Expressions: Vitamin C Preventive Role. Frontiers in pharmacology. vol 12. 2021-05-16. PMID:33986679. |
serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured. |
2021-05-16 |
2023-08-13 |
rat |