| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mayada M El-Gizawy, Eman N Hosny, Hagar H Mourad, Amira N Abd-El Razi. Curcumin nanoparticles ameliorate hepatotoxicity and nephrotoxicity induced by cisplatin in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 10. 2021-08-11. PMID:32447466. |
cisplatin induced significant increases in the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) and in the levels of bilirubin, urea, uric acid and creatinine. |
2021-08-11 |
2023-08-13 |
rat |
| Zhi-Bin Jiang, Jie Gao, Yi-Hui Chai, Wen Li, Yun-Feng Luo, Yun-Zhi Che. Astragaloside alleviates alcoholic fatty liver disease by suppressing oxidative stress. The Kaohsiung journal of medical sciences. vol 37. issue 8. 2021-08-10. PMID:33973356. |
reactive oxygen species (ros), triglyceride, total cholesterol, low-density lipoprotein, albumin, ferritin, bilirubin, superoxide dismutase, aspartate aminotransferase (ast), and alanine aminotransferase (alt) were examined using commercial kits. |
2021-08-10 |
2023-08-13 |
rat |
| Yu Wang, Yuan Tian, Nan Zhang, Xia Li, Xiujuan Wang, Weili Wang, Jun Zhang, Chunhong Piao, Yuhua Wang, Jingsheng Li. Food & function. vol 12. issue 15. 2021-08-09. PMID:34126631. |
the western blot results suggested that pp04 ameliorated the increase of intestinal permeability by dramatically increasing the expressions of tight junction proteins, such as occludin, claudin-1 and zo-1, which decreased hepatic lipopolysaccharides (lps), alanine aminotransferase (alt) and aspartate aminotransferase (ast) concentrations to effectively alleviate the liver injury. |
2021-08-09 |
2023-08-13 |
mouse |
| Shuxia Jiang, Taining Guo, Shihui Guo, Jiang Gao, Yingdong Ni, Wenqiang Ma, Ruqian Zha. Chronic Variable Stress Induces Hepatic Fe(II) Deposition by Up-Regulating ZIP14 Expression via miR-181 Family Pathway in Rats. Biology. vol 10. issue 7. 2021-08-09. PMID:34356508. |
the exposure of rats to cvs increased plasma aspartate aminotransferase (ast), alkaline phosphatase (alp) and hepatic malondialdehyde (mda) levels, but decreased glutathione peroxidase (gsh-px) activity, resulting in liver damage. |
2021-08-09 |
2023-08-13 |
rat |
| Amandeep Singh, Rajat Garg, Rocio Lopez, Naim Alkhour. Diabetes Liver Fibrosis Score to Detect Advanced Fibrosis in Diabetics with Nonalcoholic Fatty Liver Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021-08-06. PMID:33434655. |
recent data suggest that commonly used fibrosis scores (nafld fibrosis score [nfs], aspartate to alanine aminotransferase ratio [ast/alt], ast to platelet ratio index, and fibrosis-4) may have low sensitivity and negative predictive value to detect af in patients with diabetes. |
2021-08-06 |
2023-08-13 |
Not clear |
| Mariana Semeniuk, Lucila Inés Ceré, Nadia Ciriaci, María Bucci-Muñoz, Ariel Dario Quiroga, Marcelo Gabriel Luquita, Stella Roma, Viviana Alicia Catania, Aldo Domingo Mottino, Juan Pablo Rigalli, María Laura Rui. Protective effect of genistein pre-treatment on paraquat hepatotoxicity in rats. Toxicology and applied pharmacology. vol 426. 2021-08-06. PMID:34214573. |
hepatic glutathione levels and plasma levels of alanine transaminase (alt) and aspartate transaminase (ast) were also measured. |
2021-08-06 |
2023-08-13 |
rat |
| Cristina Oana Daciana Teodorescu, Florica Șandru, Adham Charkaoui, Andrei Teodorescu, Amorin Remus Popa, Andreea-Iuliana Miro. The dynamic changes in the pattern of liver function tests in pregnant obese women. Experimental and therapeutic medicine. vol 22. issue 3. 2021-08-06. PMID:34345268. |
demographic data taken into account included age, body mass index (bmi), provenance environment, anthropometric data: abdominal circumference and the complete set of paraclinical data from which we extracted these specific liver tests: aspartate aminotransferase (ast), alanine transferase (alt), direct bilirubin (bd), serum albumin and gamma-glutamyl transferase (ggt). |
2021-08-06 |
2023-08-13 |
Not clear |
| Huda Fatima, Deepti Avasth. Acute Severe Transaminitis as a Unique Presentation of Chronic Cholecystitis. Cureus. vol 13. issue 7. 2021-08-06. PMID:34350071. |
the hepatocellular function can be evaluated using aspartate aminotransferase (ast) and alanine aminotransferase (alt) which are biochemical markers of the liver. |
2021-08-06 |
2023-08-13 |
Not clear |
| Małgorzata Jasiewicz, Michał Siedlaczek, Michał Kasprzak, Diana A Gorog, Bernd Jilma, Jolanta Siller-Matula, Karolina Obońska, Ryszard Dobosiewicz, Krzysztof Pstrągowski, Jacek Kubic. Elevated serum transaminases in patients with acute coronary syndromes: Do we need a revision of exclusion criteria for clinical trials? Cardiology journal. 2021-08-06. PMID:34355781. |
elevations of hepatic transaminase (serum alanine transaminase [alt] and serum aspartate aminotransferase [ast]) levels in patients with acute coronary syndrome (acs), although transient, may result in exclusions from clinical efficacy trials due to suspected liver disease. |
2021-08-06 |
2023-08-13 |
Not clear |
| Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, Jose E Manautou, Xiao-Bo Zhon. Drug metabolism and disposition: the biological fate of chemicals. 2021-08-05. PMID:34348940. |
severity of liver damage was determined at 24, 48, 72, and 96 hours by plasma levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), microrna mir122, and tissue staining. |
2021-08-05 |
2023-08-13 |
mouse |
| Lucas D Ward, Ho-Chou Tu, Chelsea B Quenneville, Shira Tsour, Alexander O Flynn-Carroll, Margaret M Parker, Aimee M Deaton, Patrick A J Haslett, Luca A Lotta, Niek Verweij, Manuel A R Ferreira, Aris Baras, Gregory Hinkle, Paul Nio. GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms. Nature communications. vol 12. issue 1. 2021-08-04. PMID:34315874. |
understanding mechanisms of hepatocellular damage may lead to new treatments for liver disease, and genome-wide association studies (gwas) of alanine aminotransferase (alt) and aspartate aminotransferase (ast) serum activities have proven useful for investigating liver biology. |
2021-08-04 |
2023-08-13 |
human |
| Basma Emad Aboulhoda, Dina Adel Abdeltawab, Laila Ahmed Rashed, Marwa Fathi Abd Alla, Hanan Dawood Yass. Hepatotoxic Effect of Oral Zinc Oxide Nanoparticles and the Ameliorating Role of Selenium in Rats: A histological, immunohistochemical and molecular study. Tissue & cell. vol 67. 2021-08-03. PMID:32949962. |
zno nps disrupted the hepatic architecture, elevated the serum liver enzyme alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) levels and caused dose-dependent decrease in the activity of the antioxidant enzymes glutathione-peroxidase, superoxide dismutase and catalase along with an increase in the lipid peroxidation product malondialdehyde. |
2021-08-03 |
2023-08-13 |
rat |
| Nanik Sulistyani, - Nurkhasana. Screening of anticancer, hepatoprotective and nephroprotective effects of ethanol extract of Elephantopus scaber L. Pakistan journal of pharmaceutical sciences. vol 33. issue 3. 2021-08-03. PMID:33191211. |
at the beginning of the 16th week, blood was collected to calculate the levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), urea and creatinine. |
2021-08-03 |
2023-08-13 |
rat |
| Ming Zhao, Jungang Ha. Dose-dependent effect of aqueous extract from Dendrobium officinale on blood lipids and lipid peroxidation in hyperlipidemic rats. Pakistan journal of pharmaceutical sciences. vol 33. issue 3. 2021-08-03. PMID:33191215. |
we determined increased serum levels of total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt), aspartate transaminase (ast), reduced serum levels of hdl-c, elevated mda levels, decreased activity of gsh-px, sod and cat in liver tissues of hyperlipidemic rats. |
2021-08-03 |
2023-08-13 |
rat |
| Yi Shao, Yuancong Jiang, Hui Li, Feng Zhang, Zhenhua Hu, Shusen Zhen. Characteristics of mouse intestinal microbiota during acute liver injury and repair following 50% partial hepatectomy. Experimental and therapeutic medicine. vol 22. issue 3. 2021-08-03. PMID:34335895. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) were determined using an automatic chemical analyzer and the gut microbiota was assessed by 16s ribosomal rna gene sequencing of small intestinal contents. |
2021-08-03 |
2023-08-13 |
mouse |
| Nergis Ekmen, Çağri Akalin, Murat Akyildi. Predictive value of protein induced by absence of vitamin K absence or antagonist II, alpha-fetoprotein and gamma-glutamyltransferase/aspartate aminotransferase ratio for the diagnosis of hepatocellular carcinoma in transplantation candidates. European journal of gastroenterology & hepatology. vol 32. issue 2. 2021-08-02. PMID:32796360. |
we investigate whether combined liver function marker such as gamma-glutamyl transferase (ggt) and aspartate aminotransferase (ast) with alpha-fetoprotein (afp) and pivka-ii increase their diagnostic predictive value in diagnosis of hcc. |
2021-08-02 |
2023-08-13 |
Not clear |
| Ming-Ming He, Zhe Fang, Dong Hang, Feng Wang, Georgios Polychronidis, Liang Wang, Chun-Han Lo, Kai Wang, Rong Zhong, Markus D Knudsen, Scott G Smith, Rui-Hua Xu, Mingyang Son. Circulating liver function markers and colorectal cancer risk: A prospective cohort study in the UK Biobank. International journal of cancer. vol 148. issue 8. 2021-08-02. PMID:33091956. |
circulating levels of liver function markers (alanine transaminase [alt], aspartate transaminase [ast], total bilirubin [tbil], gamma glutamyltransferase [ggt], alkaline phosphatase [alp], total protein [tp] and albumin [alb]) were measured. |
2021-08-02 |
2023-08-13 |
human |
| b' Beng\\xc3\\xbcl G\\xc3\\xbcrsoy, Cemile D S\\xc3\\xbcrmeli, Mustafa Alkan, Celal Sat\\xc4\\xb1c\\xc4\\xb1, Elif Sarg\\xc4\\xb1n Altunok, Sadettin Kamat, Berna Demirok, Mustafa A Demirkol, Akaberk B\\xc3\\xb6r\\xc3\\xb. Cytokine storm in severe COVID-19 pneumonia. Journal of medical virology. vol 93. issue 9. 2021-07-30. PMID:33963559.' |
for the patients with confirmed covid-19 infection, after they become complicated with severe pneumonia, lymphocytopenia (55.3%), anemia (12.0%), thrombocytopenia (19.3%), hyperferritinemia (72.5%), hyperfibrinogenemia (63.7%) and elevated lactate dehydrogenase (ldh) (90.8%), aspartate aminotransaminase (ast) (31.3%), alanine aminotransaminase (alt) (20.7%) are detected. |
2021-07-30 |
2023-08-13 |
Not clear |
| Sundar Khadka, Roshan Pandit, Subhash Dhital, Jagat Bahadur Baniya, Surendra Tiwari, Bimal Shrestha, Sanjeet Pandit, Fumitaka Sato, Mitsugu Fujita, Mukunda Sharma, Ikuo Tsunoda, Shravan Kumar Mishr. Evaluation of Five International HBV Treatment Guidelines: Recommendation for Resource-Limited Developing Countries Based on the National Study in Nepal. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 27. issue 1. 2021-07-30. PMID:34321716. |
although four guidelines recommend elastography to assess liver cirrhosis, the who guideline alternatively recommends using the aspartate aminotransferase (ast)-to-platelet ratio index (apri), which is inexpensive and conducted routinely in most hospitals. |
2021-07-30 |
2023-08-13 |
Not clear |
| Eyad Gadour, Zeinab Hassan, Rajaey Gadou. A Comprehensive Review of Transaminitis and Irritable Bowel Syndrome. Cureus. vol 13. issue 7. 2021-07-30. PMID:34322359. |
the prevalence of elevated alt with other liver enzymes (γ-gt levels and aspartate aminotransferase (ast)) in patients with irritable bowel syndrome whether their body mass index (bmi) was high or not (16.9% vs. 7.7%; |
2021-07-30 |
2023-08-13 |
human |