| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S C Litin, J F O'Brien, S Pruett, R W Forsman, M F Burritt, L G Bartholomew, W P Baldu. Macroenzyme as a cause of unexplained elevation of aspartate aminotransferase. Mayo Clinic proceedings. vol 62. issue 8. 1987-08-27. PMID:3600038. |
aspartate aminotransferase (ast) can exist as a macroenzyme by forming a complex with an immunoglobulin. |
1987-08-27 |
2023-08-11 |
Not clear |
| D A Adelekan, A D Adekile, D I Thurnha. Dependence of pyridoxine metabolism on riboflavin status in sickle cell patients. The American journal of clinical nutrition. vol 46. issue 1. 1987-08-07. PMID:3604973. |
aspartate transaminase (ast) activities in scd patients were double those in control subjects. |
1987-08-07 |
2023-08-11 |
human |
| W O Young, P J Goldschmidt-Clermont, D L Emerson, W M Lee, D J Jollow, R M Galbrait. Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein). The Journal of laboratory and clinical medicine. vol 110. issue 1. 1987-07-29. PMID:3598340. |
liver damage was monitored by aspartate aminotransferase (ast) activity and by histologic examination, and serum gc was analyzed by polyacrylamide gel electrophoresis (page) and transblotting with anti-gc. |
1987-07-29 |
2023-08-11 |
Not clear |
| P R Donald, J F Schoeman, A O'Kenned. Hepatic toxicity during chemotherapy for severe tuberculosis meningitis. American journal of diseases of children (1960). vol 141. issue 7. 1987-07-22. PMID:2884866. |
of 33 children observed for at least eight weeks, only five (15%) had normal serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and gamma-glutamyl transferase levels throughout, but in only three patients were ast or alt values greater than 200 u/l, and enzyme levels tended to normalize toward the end of the period. |
1987-07-22 |
2023-08-11 |
Not clear |
| S Mizrahi, L Dolberg, W Z Jacobsoh. Alteration in aminotransferase levels in rats after acute hepatic injury. Israel journal of medical sciences. vol 23. issue 3. 1987-06-30. PMID:3583700. |
measurement of serial aspartate aminotransferase (ast) and alanine aminotransferase (alt)--formerly got and gpt--in both serum and urine, were carried out in rats with hepatocellular injury induced by ingestion of carbon tetrachloride. |
1987-06-30 |
2023-08-11 |
rat |
| M Gomez-Bautista, F A Rojo-Vazquez, J M Alund. The effect of the host's age on the pathology of Eimeria stiedai infection in rabbits. Veterinary parasitology. vol 24. issue 1-2. 1987-06-26. PMID:2884769. |
over 50 days of infection, the serum activities of aspartate (ast) and alanine (alt) aminotransferases, alkaline phosphatase (ap) and gamma-glutamyltranspeptidase (ggtp) were analyzed as indicators of hepatic lesions and total serum globulins with respect to the immune response of the host; parasite development was followed by oocyst output; weight gain, food intake and relative liver weight were analyzed to control the performance of infected animals. |
1987-06-26 |
2023-08-11 |
Not clear |
| P H Phillips, G E For. Clinical, haematological and plasma biochemical changes in specified-pathogen-free (sporozoa) lambs experimentally infected with low numbers of Sarcocystis tenella sporocysts. Veterinary parasitology. vol 24. issue 1-2. 1987-06-26. PMID:2954299. |
lactate dehydrogenase (ldh) of group 2 was elevated at 24 and 28 dpi and from 42 to 78 dpi, while aspartate aminotransferase (ast) of the same group was elevated from 45 to 66 dpi. |
1987-06-26 |
2023-08-11 |
Not clear |
| P Attali, S Prod'Homme, G Pelletier, L Papoz, O Ink, C Buffet, J P Etienn. Prognostic factors in patients with hepatocellular carcinoma. Attempts for the selection of patients with prolonged survival. Cancer. vol 59. issue 12. 1987-06-23. PMID:3032403. |
multivariate analysis found a negative relationship between a survival time longer than 60 days and five of these variables; these variables were in decreasing order: encephalopathy, alcohol consumption, aspartate amino transferase (ast), blood urea nitrogen, and total bilirubin. |
1987-06-23 |
2023-08-11 |
Not clear |
| M A Holmes, R B Weiskop. Determination of plasma volume in swine by the enzyme-dilution method. The American journal of physiology. vol 252. issue 5 Pt 2. 1987-06-17. PMID:3555120. |
plasma volume of six young swine was determined by simultaneous dilution in the plasma of two purified porcine enzymes, aspartate aminotransferase (ast) and alanine aminotransferase (alt), and evans blue dye. |
1987-06-17 |
2023-08-11 |
Not clear |
| J de Schepper, J van der Stock, E Capia. The characteristic pattern of aspartate aminotransferase and alanine aminotransferase in the bitch with the cystic hyperplasia-pyometra complex: effect of medical or surgical treatment. Veterinary research communications. vol 11. issue 1. 1987-06-16. PMID:3472412. |
in 75 clinically normal unspayed female control dogs between two and eleven years old the average plasma level of aspartate aminotransferase (ast) was 21.6 +/- 5.7 (+/- sd) iu/l, of alanine aminotransferase (alt) 40.4 +/- 13.0 iu/l and of the ast/alt ratio 0.6 +/- 0.2. |
1987-06-16 |
2023-08-11 |
Not clear |
| A A Nanji, S W French, J B Freema. Serum alanine aminotransferase to aspartate aminotransferase ratio and degree of fatty liver in morbidly obese patients. Enzyme. vol 36. issue 4. 1987-05-29. PMID:3569188. |
we evaluated the change in serum alanine aminotransferase (alt; ec 2.6.1.2) to serum aspartate aminotransferase (ast; ec 2.6.1.; alt/ast) ratio with the degree of fatty liver in morbidly obese patients. |
1987-05-29 |
2023-08-11 |
Not clear |
| T Yoshikawa, L P Ruhr, W Flory, M I Banton, D Giamalva, D F Church, W A Pryo. Toxicity of polycyclic aromatic hydrocarbons. III. Effects of beta-naphthoflavone pretreatment on hepatotoxicity of compounds produced in the ozonation or NO2-nitration of phenanthrene and pyrene in rats. Veterinary and human toxicology. vol 29. issue 2. 1987-05-27. PMID:3576942. |
no increase in the level of aspartate aminotransferase (ast), alanine aminotransferase (alt) or sorbitol dehydrogenase (sdh) was seen in the pretreated rats 48 hr after the treatment. |
1987-05-27 |
2023-08-11 |
rat |
| L Müller, M Wilhel. Uptake and distribution of aluminium in rat hepatocytes and its effect on enzyme leakage and lactate formation. Toxicology. vol 44. issue 2. 1987-05-20. PMID:3564054. |
concomitantly, the leakage of lactate dehydrogenase (ldh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) increased in the presence of al time- and concentration-dependently, but only to a moderate extent. |
1987-05-20 |
2023-08-11 |
rat |
| P E Hickman, W Silvester, A A Musk, G H McLellan, A Harri. Cardiac enzyme changes in myxedema coma. Clinical chemistry. vol 33. issue 4. 1987-05-18. PMID:3829411. |
a 74-year-old man with myxedema and hypothermia had increased activities in plasma of creatine kinase (ck; ec 2.7.3.2), aspartate aminotransferase (ast; ec 2.6.1.1), and lactate dehydrogenase (ld; ec 1.1.1.27) and increased proportions of ck-mb (up to 20% of total ck) and ld1 isoenzymes, but no clinical or investigational evidence of associated myocardial infarction. |
1987-05-18 |
2023-08-11 |
Not clear |
| V A Protsenko, V Z Kharchenko, Iu N Kolesnikov, I F Spitsyn, V E Egoryche. [Effect of kontrikal on the dynamics of proteolytic system indices in postischemic toxemia]. Farmakologiia i toksikologiia. vol 50. issue 1. 1987-05-13. PMID:2435573. |
it was shown in wistar male rats that the development of tourniquet shock was followed by an increase of proteolytic activity in the blood by 3 times, activity of aspartate aminotransferase (ast) by 3 times, that of alanine aminotransferase (alt) by 6 times, contents of urea and residual nitrogen by 2.5-3 times; level of alpha 1-protease inhibitor (alpha 1-pi) decreased by 4 times and that of alpha 2-macroglobulin (alpha 2mg) by 2.5 times. |
1987-05-13 |
2023-08-11 |
rat |
| M O Paz, F Brenes, P Karayiannis, T P Jowett, P J Scheuer, H C Thoma. Chronic hepatitis B virus infection. Viral replication and patterns of inflammatory activity: serological, clinical and histological correlations. Journal of hepatology. vol 3. issue 3. 1987-05-11. PMID:3549868. |
hbv dna positivity correlated with the presence of hepatitis b e antigen (hbeag, p less than 0.001) and aspartate transaminase (ast) levels (p less than 0.005). |
1987-05-11 |
2023-08-11 |
Not clear |
| C W Davy, P N Trennery, J G Edmunds, J F Altman, D A Eichle. Local myotoxicity of ketamine hydrochloride in the marmoset. Laboratory animals. vol 21. issue 1. 1987-04-29. PMID:3104668. |
an investigation of raised plasma aspartate aminotransferase (ast) in marmosets after intramuscular ketamine injection suggested a local myotoxicity. |
1987-04-29 |
2023-08-11 |
marmoset |
| F Okuno, M Arai, H Ishii, Y Shigeta, Y Ebihara, S Takagi, M Tsuchiy. Mild but prolonged elevation of serum angiotensin converting enzyme (ACE) activity in alcoholics. Alcohol (Fayetteville, N.Y.). vol 3. issue 6. 1987-04-22. PMID:3028446. |
in contrast to the rapid normalization of such enzymes as aspartate transaminase (ast), alanine transaminase (alt) and lactic dehydrogenase (ldh) which represent parenchymal liver cell injury, the activity of ace remained elevated over a period of 4 weeks even with abstinence. |
1987-04-22 |
2023-08-11 |
Not clear |
| G Kovác, P Mudron, M Prosbová, J Pasték. [Clinical and biochemical response in the prevention of nutritional myodystrophy in heifers]. Veterinarni medicina. vol 32. issue 2. 1987-04-14. PMID:3103311. |
sensitive indicators of the break-down of muscular tissue were the enzymes aspartate aminotransferase (ast), alanine aminotransferase (alt), and mainly creatinine kinase (cpk): the activities of these enzymes increased significantly after the heifers had been driven to pasture. |
1987-04-14 |
2023-08-11 |
cattle |
| T Yoshikawa, W Flory, L P Ruhr, D Giamalva, D F Church, W A Pryo. Toxicity of polycyclic aromatic hydrocarbons. II. Effect of NO2-nitrated phenanthrene and pyrene on blood chemistry in rats. Veterinary and human toxicology. vol 29. issue 1. 1987-04-02. PMID:3824871. |
phenanthrene produced a significant elevation of serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels relative to dmso-injected rats 24 hr after injection. |
1987-04-02 |
2023-08-11 |
rat |