Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E A Hassoun, D Bagchi, V F Roche, S J Stoh. An assessment of potential chemoprotectant activity against ricin toxicity by mechanism based glycosidase inhibitors in macrophage J744A.1 cell cultures. Toxicon : official journal of the International Society on Toxinology. vol 30. issue 12. 1993-02-24. PMID:1488763. |
of the six compounds which were tested, only n-bromoacetyl-alpha-d-galactopyranosylamine and n-bromoacetyl-beta-d-galactopyranosylamine exhibited significant activity against ricin toxicity, as indicated by the release of lactate dehydrogenase (ldh) and aspartate aminotransferase (ast). |
1993-02-24 |
2023-08-11 |
Not clear |
S Valberg, L Jönsson, A Lindholm, N Holmgre. Muscle histopathology and plasma aspartate aminotransferase, creatine kinase and myoglobin changes with exercise in horses with recurrent exertional rhabdomyolysis. Equine veterinary journal. vol 25. issue 1. 1993-02-24. PMID:8422878. |
at rest, plasma aspartate aminotransferase (ast) activities in horses with rer were above 95% confidence intervals for control horses. |
1993-02-24 |
2023-08-12 |
Not clear |
I K Quaye, P K Nyame, D Dodoo, B Gyan, A A Adje. Biochemical and haematological markers of alcohol intake in Ghanaians. West African journal of medicine. vol 11. issue 3. 1993-02-05. PMID:1362076. |
the serum gamma-glutamyltransferase (ggt), aspartate aminotransferase (ast), urate and triglyceride and mean cell volume (mcv) were determined in 60 total abstainers, 56 social drinkers and 100 alcoholics. |
1993-02-05 |
2023-08-11 |
Not clear |
I K Quaye, P K Nyame, D Dodoo, B Gyan, A A Adje. Biochemical and haematological markers of alcohol intake in Ghanaians. West African journal of medicine. vol 11. issue 3. 1993-02-05. PMID:1362076. |
gamma-glutamyltransferase (ggt), aspartate aminotransferase (ast), and urate are sensitive enough to detect people who take in alcohol regularly and yet may be regarded as normal and not alcohol dependent. |
1993-02-05 |
2023-08-11 |
Not clear |
M C Sharma, L M Tripathi, P Sagar, G P Dutta, V C Pande. Cerebral ammonia levels and enzyme changes during Plasmodium yoelii infection in mice. The Journal of tropical medicine and hygiene. vol 95. issue 6. 1993-01-13. PMID:1361009. |
ammonia, lactate and glutamate levels and the activities of glutamine synthetase (gs), glutamate dehydrogenase (gdh), glutaminase (gln), aspartate transaminase (ast), phosphofructokinase (pfk) and monoamine oxidase (mao) were compared in the brain tissue of normal and p. yoelii infected mice. |
1993-01-13 |
2023-08-11 |
mouse |
J Pedraza-Chaverri, C Cruz, E Tapia, J C Peñ. Activity of serum enzymes in puromycin aminonucleoside-induced nephrotic syndrome. Renal failure. vol 14. issue 4. 1993-01-13. PMID:1462003. |
total serum protein, serum albumin, total urine protein excretion, and the serum activity of several enzymes--aldolase (als), cholinesterase (chs), leucine aminopeptidase (lap), isocitrate dehydrogenase (icd), aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), alpha-hydroxybutyrate dehydrogenase (hbd), creatine kinase (ck), alkaline phosphatase (alp), and gamma-glutamyl transferase (ggt)--were estimated in rats with nephrotic syndrome (ns) at 2, 4, 6, 8, 10, 12, 16, 20, and 30 days after a single injection of puromycin aminonucleoside (pan). |
1993-01-13 |
2023-08-11 |
rat |
H Takenaka, K Iwase, S Ohshima, T Hiranak. A new technique for the resection of gastric cancer: modified Appleby procedure with reconstruction of hepatic artery. World journal of surgery. vol 16. issue 5. 1993-01-11. PMID:1462635. |
postoperatively, serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were determined for evaluation of liver function. |
1993-01-11 |
2023-08-11 |
Not clear |
H S Tang, O Y H. Assessment of liver function using a novel galactose single point method. Digestion. vol 52. issue 3-4. 1993-01-08. PMID:1334011. |
positive correlations were observed between gsp, gec, mgec and ast (serum aspartate aminotransferase), alt (serum alanine aminotransferase), serum bilirubin, albumin, prothrombin time and r-globulin. |
1993-01-08 |
2023-08-11 |
human |
C Bai, P J Canfield, N H Stace. Individual serum bile acids as early indicators of carbon tetrachloride- and chloroform-induced liver injury. Toxicology. vol 75. issue 3. 1993-01-07. PMID:1455431. |
serum samples were assayed for liver injury by determination of alanine aminotransferase (alt), aspartate amino-transferase (ast), alkaline phosphatase (alp), bilirubin and total bile acid (by enzymatic kit). |
1993-01-07 |
2023-08-11 |
rat |
D K Garg, R N Goya. Haematological and hepatotoxic effects of silken styles of corn in albino rats. Journal of applied toxicology : JAT. vol 12. issue 5. 1992-12-24. PMID:1447482. |
the following haematological values were significantly reduced on the 7th and 21st day following extract administration: haemoglobin (hb), red blood corpuscles (rbc), clotting time (ct), mean corpuscular volume (mcv), haematocrit (ht), serum glucose, blood urea nitrogen (bun), cholesterol, aspartate transaminase (ast), alanine transaminase (alt), calcium, total protein, total albumin and total acid phosphatase; and white blood corpuscles (wbc), mean corpuscular haemoglobin (mch), mean corpuscular haemoglobin concentration (mchc), alkaline phosphatase and creatinine increased. |
1992-12-24 |
2023-08-11 |
rat |
A Richter, C Gerdes, W Lösche. Atypical reactions to halothane in a subgroup of homozygous malignant hyperthermia(MH)-susceptible pigs: indication of a heterogenous genetic basis for the porcine syndrome. DTW. Deutsche tierarztliche Wochenschrift. vol 99. issue 10. 1992-12-23. PMID:1425316. |
the typical mh was characterized by sudden appearance of tachycardia, muscle rigidity with typical extension of the hindlimbs, increase of body temperature, acidosis-caused by rapid increase of co2 and lactate production-, hyperkalaemia and increased activity of creatine kinase (ck) and aspartate transaminase (ast). |
1992-12-23 |
2023-08-11 |
Not clear |
N P Skakun, O E Tabachu. [The comparative action of isoniazid, rifampicin and ethambutol on liver function]. Eksperimental'naia i klinicheskaia farmakologiia. vol 55. issue 2. 1992-12-22. PMID:1422454. |
this is supported by activation of aspartate and alanine aminotransferases, (alt and ast), alkaline phosphatase in blood serum and acid phosphatase in the liver, by a decrease of the activity of na(+)-, k(+)-atpase, succinate dehydrogenase and cytochromoxidase in the liver, lowering of the rate of bile secretion, excretion of bile acids, bilirubin and cholesterol with bile. |
1992-12-22 |
2023-08-11 |
rat |
K Yoneda, Y Katayama, T Koike, I Tanimiz. A homogeneous assay system of aspartate aminotransferase iso-enzymes using proteases and application for clinical evaluation of myocardial infarction. Journal of clinical laboratory analysis. vol 6. issue 6. 1992-12-22. PMID:1432361. |
we designed a rapid, homogeneous assay for human aspartate aminotransferase (ast) isoenzymes, by a selective proteolysis of soluble ast (s-ast), using chymotrypsin and protease 401. |
1992-12-22 |
2023-08-11 |
human |
S Yamini, N Carswell, O E Michaelis, B Szepes. Adaptation in enzyme (metabolic) pathways to obesity, carbohydrate diet and to the occurrence of NIDDM in male and female SHR/N-cp rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 16. issue 10. 1992-12-17. PMID:1330956. |
liver glucose-6-phosphatase (g6pase), fructose 1,6-bisphosphatase (fbpase), phosphoenolpyruvate carboxykinase (pepck), glucose-6-phosphate dehydrogenase (g6pdh), 6-phosphogluconate dehydrogenase (6pgdh), malic enzyme (me), phosphofructokinase (pfk), glucokinase (gk), aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels (per total liver capacity) were significantly affected by phenotype (obese > lean). |
1992-12-17 |
2023-08-11 |
rat |
A van der Laarse, L Hollaar, S W Kok, S van den Eijnde, J H Souverijn, P J Hoedemaeker, A V Bruschk. Myocardial creatine kinase-MB concentration in normal and explanted human hearts and released from hearts of patients with acute myocardial infarction. Clinical physiology and biochemistry. vol 9. issue 1. 1992-12-17. PMID:1424434. |
by calculation of cumulatively released amounts of ck-mb and cumulatively released activities of ck, aspartate aminotransferase (ast) and alpha-hydroxybutyrate dehydrogenase (hbdh), we obtained values of the proportions in which these quantities were released from the myocardium. |
1992-12-17 |
2023-08-11 |
human |
R J Nuviala, L Roda, M G Lapieza, B Boned, A Gine. Serum enzymes activities at rest and after a marathon race. The Journal of sports medicine and physical fitness. vol 32. issue 2. 1992-12-10. PMID:1434588. |
enzymes such as aspartate aminotransferase (ast) and lactate dehydrogenase (ldh), which are widely distributed in the tissues, were found to have undergone more marked variations and these could not be related to the changes in the volume of the plasma, while in enzymes of muscular origin such as aldolase (ald), creatine kinase (ck) and its cardiac isoenzyme (ck-mb), notable increases were observed due to the muscular injury suffered. |
1992-12-10 |
2023-08-11 |
Not clear |
M V Berezkin, E N Gratsinskiĭ, V F Kudinova, A N Batygov, L E Ponomareva, O A Prikazchikova, G N Zhukov. [Seasonal and circadian fluctuations in blood biochemical indicators in mice in natural conditions and exposed to constant light]. Biulleten' eksperimental'noi biologii i meditsiny. vol 114. issue 7. 1992-12-01. PMID:1421318. |
the fluctuations of activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt) and those of the levels of protein, glucose, cholesterol, bilirubin, creatinine, blood urea nitrogen, k+, cl-, na+ in blood plasma of mice in natural conditions (nc) and exposed to constant light (cl) were studied in different seasons of the year (in january, april, july, october) on days 18, 24, 6 (at 12 o'clock). |
1992-12-01 |
2023-08-11 |
mouse |
G A Brazeau, M Mathew, R K Entriki. Serum and organ indices of the mdx dystrophic mouse. Research communications in chemical pathology and pharmacology. vol 77. issue 2. 1992-11-27. PMID:1439189. |
increases in serum lactate dehydrogenase (ldh), alkaline phosphatase (ap), aspartate transaminase (ast), and cholesterol levels, combined with an increase in liver weight and a decrease in cytochrome p-450, suggests the possibility of hepatic dysfunction. |
1992-11-27 |
2023-08-11 |
mouse |
S N Lichtman, E E Okoruwa, J Keku, J H Schwab, R B Sarto. Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. The Journal of clinical investigation. vol 90. issue 4. 1992-11-13. PMID:1401067. |
buffer treatment, ursodeoxycholic acid, prednisone, methotrexate, and cyclosporin a failed to prevent sbbo-induced injury as demonstrated by increased plasma aspartate aminotransferase (ast) and elevated histology scores. |
1992-11-13 |
2023-08-11 |
rat |
P H Lolekha, P Nitipaichi. User-defined serum aspartate and alanine aminotransferase, cholesterol, triglycerides, urea, and uric acid for the Beckman synchron CX 4/5 using Ames Sera-Pak reagents. Journal of clinical laboratory analysis. vol 6. issue 5. 1992-11-13. PMID:1403344. |
beckman aspartate aminotransferase (ast), alanine aminotransferase (alt), cholesterol, triglycerides, urea, and uric acid liquid reagents for synchron cx 4/5 (48, 48, 25, 60, 26, and 30 cents us/test, respectively) are expensive. |
1992-11-13 |
2023-08-11 |
Not clear |