| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S K Kim, Y C Kim, Y C Ki. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 36. issue 8. 1998-09-17. PMID:9734716. |
administration of betaine (1000 mg/kg, ip) 1 to 7 hr prior to a chloroform challenge (0.25 ml/kg, ip) resulted in remarkable enhancement of hepatotoxicity as indicated by increases in serum sorbitol dehydrogenase (sdh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities. |
1998-09-17 |
2023-08-12 |
mouse |
| L A Kotkoskie, C Freema. Subchronic oral toxicity study of Aquacoat ECD ethylcellulose aqueous dispersion in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 36. issue 8. 1998-09-17. PMID:9734721. |
significantly decreased total protein and globulin levels and increases in alanine aminotransferase (alt) and aspartate aminotransferase (ast) in male rats receiving 2709 and 4515 mg aquacoat ecd/kg/day were considered to be treatment related. |
1998-09-17 |
2023-08-12 |
rat |
| b' S Dobri\\xc4\\x87, V Dragojevi\\xc4\\x87-Simi\\xc4\\x87, D Bokonji\\xc4\\x87, S Milovanovi\\xc4\\x87, D Marinci\\xc4\\x87, P Jovi\\xc4\\x8. The efficacy of selenium, WR-2721, and their combination in the prevention of adriamycin-induced cardiotoxicity in rats. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 17. issue 3-4. 1998-09-11. PMID:9726805.' |
and (2) the serum activity of creatine kinase (ck), aspartate aminotransferase-(ast), lactate dehydrogenase (ldh), and its isoenzyme alpha-hydroxybutyrate dehydrogenase (alpha-hbdh). |
1998-09-11 |
2023-08-12 |
rat |
| B L Schneider, A K Kiupakis, L J Reitze. Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli. Journal of bacteriology. vol 180. issue 16. 1998-09-04. PMID:9696779. |
overproduction of ast enzymes resulted in faster growth with arginine and aspartate. |
1998-09-04 |
2023-08-12 |
Not clear |
| S Yokochi, Y Ishiwata, H Hashimoto, F Ninomiya, T Suzuk. Hepatoprotective effect of propagermanium on Corynebacterium parvum and lipopolysaccharide-induced liver injury in mice. Scandinavian journal of immunology. vol 48. issue 2. 1998-09-04. PMID:9716110. |
oral pretreatment with propagermanium decreased alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity in a dose-dependent manner. |
1998-09-04 |
2023-08-12 |
mouse |
| G Fortunato, R Iorio, P Esposito, M M Lofrano, A Vegnente, P Vajr. Macroenzyme investigation and monitoring in children with persistent increase of aspartate aminotransferase of unexplained origin. The Journal of pediatrics. vol 133. issue 2. 1998-09-03. PMID:9709724. |
ten children with asymptomatic persistent cryptogenic increased serum levels of aspartate aminotransferase (ast) were screened for detection and monitoring of ast macroenzyme (macroast). |
1998-09-03 |
2023-08-12 |
Not clear |
| J Kobayashi, I Takeyoshi, S Ohwada, K Iwanami, K Matsumoto, M Muramoto, Y Morishit. The effects of FR167653 in extended liver resection with ischemia in dogs. Hepatology (Baltimore, Md.). vol 28. issue 2. 1998-08-31. PMID:9696012. |
hepatic venous blood was collected to measure alanine transaminase (alt), aspartate transaminase (ast), lactate dehydrogenase (ldh), purine nucleoside phosphorylase (pnp), and hyaluronic acid (ha) levels, and il-1beta expression was also measured by reverse-transcriptase polymerase chain reaction (rt-pcr). |
1998-08-31 |
2023-08-12 |
dog |
| M Iwai, T Yamauchi, T Shimaz. Endothelin 1 aggravates acute liver injury in perfused livers of rats after treatment with D-galactosamine. Hepatology (Baltimore, Md.). vol 28. issue 2. 1998-08-31. PMID:9696017. |
in control liver perfused in situ with constant pressure, infusion of et-1 into the portal vein at a concentration of 0.1 nmol/l decreased the flow rate without a significant leakage of lactate dehydrogenase (ldh) or aspartate transaminase (ast) into the effluent. |
1998-08-31 |
2023-08-12 |
rat |
| N Rakba, F Aouad, C Henry, C Caris, I Morel, P Baret, J L Pierre, P Brissot, R J Ward, G Lescoat, R R Crichto. Iron mobilisation and cellular protection by a new synthetic chelator O-Trensox. Biochemical pharmacology. vol 55. issue 11. 1998-08-31. PMID:9714298. |
the protective effect of o-trensox against iron toxicity induced in hepatocyte cultures by ferric citrate was shown by decreased release of the enzymes lactate dehydrogenase (ldh), aspartate aminotransferase (ast), and alanine aminotranferase (alt) from the cultures and, using electron paramagnetic resonance (epr) measurements, decreased production of lipid radicals. |
1998-08-31 |
2023-08-12 |
rat |
| F L Altice, F Mostashari, P A Selwyn, P J Checko, R Singh, S Tanguay, E A Blanchett. Predictors of HIV infection among newly sentenced male prisoners. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. vol 18. issue 5. 1998-08-31. PMID:9715840. |
laboratory markers such as hypoalbuminemia, an elevated aspartate aminotransferase (ast) level, leukopenia, anemia, and thrombocytopenia suggest increased risk for hiv among prisoners, particularly in settings where hiv testing resources are scarce. |
1998-08-31 |
2023-08-12 |
Not clear |
| M Y Wong, C L Lu, C M Liu, L T Hou, W K Chan. Clinical response of localized recurrent periodontitis treated with scaling, root planing, and tetracycline fiber. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 97. issue 7. 1998-08-27. PMID:9700247. |
thirty patients who were receiving supportive treatment and had at least two nonadjacent periodontitis sites with a probing depth of between 4 and 8 mm and bleeding on probing, or had aspartate aminotransferase (ast) levels above 800 microiu in the gingival crevicular fluid in separate quadrants participated in this study. |
1998-08-27 |
2023-08-12 |
human |
| T Nishiyama, K Hanaok. Inorganic fluoride kinetics and renal and hepatic function after repeated sevoflurane anesthesia. Anesthesia and analgesia. vol 87. issue 2. 1998-08-26. PMID:9706952. |
blood urea nitrogen, serum creatinine, serum and urine beta2-microglobulin, urine n-acetyl-beta-d-glucosaminidase, serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and total bilirubin concentrations were measured up to 7 days after anesthesia. |
1998-08-26 |
2023-08-12 |
Not clear |
| b' V Karan, S Vitorovi\\xc4\\x87, V Tutundzi\\xc4\\x87, V Poleksi\\xc4\\x8. Functional enzymes activity and gill histology of carp after copper sulfate exposure and recovery. Ecotoxicology and environmental safety. vol 40. issue 1-2. 1998-08-21. PMID:9626535.' |
after a 14-day period of exposure to five concentrations of copper sulfate (0.25-4.0 mg/l cuso4, values ranging from approximately 5 to 70% of the 96-h lc-50) and a recovery period of the same duration, activities of the functional enzymes alkaline phosphatase (ap), aspartate aminotransferase (ast), and alanine aminotransferase (alt) in the blood serum and gills were determined. |
1998-08-21 |
2023-08-12 |
Not clear |
| Y C Kim, S J Le. Temporal variation in hepatotoxicity and metabolism of acetaminophen in mice. Toxicology. vol 128. issue 1. 1998-08-20. PMID:9704905. |
at 08:00, 14:00 or 20:00 h. apap at this dose was markedly hepatotoxic to mice when administered at 20:00 h as determined by increases in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, and by decreases in hepatic glucose-6-phosphatase (g-6-pase) activity. |
1998-08-20 |
2023-08-12 |
mouse |
| M L Queiroz, C Bincoletto, R C Perlingeiro, M R Quadros, C A Souz. Immunoglobulin levels in workers exposed to hexachlorobenzene. Human & experimental toxicology. vol 17. issue 3. 1998-08-19. PMID:9587786. |
hepatic function was evaluated by serum aspartate (ast) and alanine aminotransferase (alt) activities, as well as by bilirubin levels. |
1998-08-19 |
2023-08-12 |
Not clear |
| S C Kim, J T Hong, S J Jang, W S Kang, H S Yoo, Y P Yu. Formation of 8-oxodeoxyguanosine in liver DNA and hepatic injury by peroxisome proliferator clofibrate and perfluorodecanoic acid in rats. The Journal of toxicological sciences. vol 23. issue 2. 1998-08-11. PMID:9644651. |
hepatic injury was evidenced by liver enlargement and by levels of serum enzymes, aspartate aminotransferase (ast) and alanine aminotransferase (alt), and hepatic gamma-glutamylpeptidase (gamma-gt) activity. |
1998-08-11 |
2023-08-12 |
rat |
| T Katayama, S Yokoyama, T Mitomi, K Watanab. Alterations in glutathione peroxidase activity following reperfusion injury to rat liver. The Tokai journal of experimental and clinical medicine. vol 22. issue 2. 1998-08-06. PMID:9608629. |
in addition, necrosis of the hepatic periportal area accompanied with remarkable rises in serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) were observed. |
1998-08-06 |
2023-08-12 |
rat |
| G D Marty, E F Freiberg, T R Meyers, J Wilcock, T B Farver, D E Hinto. Viral hemorrhagic septicemia virus, Ichthyophonus hoferi, and other causes of morbidity in Pacific herring Clupea pallasi spawning in Prince William Sound, Alaska, USA. Diseases of aquatic organisms. vol 32. issue 1. 1998-08-06. PMID:9676259. |
i. hoferi infections were associated with severe, disseminated, granulomatous inflammation and with increased levels of plasma creatine phosphokinase (cpk) and aspartate aminotransferase (ast). |
1998-08-06 |
2023-08-12 |
Not clear |
| J S Bagia, D S Perera, D L Morri. Renal impairment in hepatic cryotherapy. Cryobiology. vol 36. issue 4. 1998-08-03. PMID:9654730. |
patients in the renal impairment group had a greater number of lesions than those of the nonrenal impairment group (3.4 vs 2.1, p < 0.01), as well as larger lesion diameter (2.9 vs 1.9, p < 0.01), increased freezing time (74.7 vs 44.3, p < 0.01), and a higher aspartate transaminase (ast) (2254 vs 1157, p < 0.01). |
1998-08-03 |
2023-08-12 |
Not clear |
| V L Vega, M Maldonado, L Mardones, V Manríquez, E Vivaldi, J Roa, P H War. Inhibition of nitric oxide synthesis aggravates hepatic oxidative stress and enhances superoxide dismutase inactivation in rats subjected to tourniquet shock. Shock (Augusta, Ga.). vol 9. issue 5. 1998-07-31. PMID:9617880. |
liver oxidative stress becomes evident after hind limb reperfusion, as evidenced by the loss of total tissue thiols; by increases in tissue oxidized glutathione (gssg), lipid peroxidation (lpo), plasma aminotransferases (alanine aminotransferase (alt) and (aspartate aminotransferase (ast)), and plasma nitrites; and by a 36% loss in total superoxide dismutase (sod) activity. |
1998-07-31 |
2023-08-12 |
rat |