| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Kashif R Zaidi, Tariq M Al-Qirim, Naheed Ban. Effects of antioxidant vitamins on glutathione depletion and lipid peroxidation induced by restraint stress in the rat liver. Drugs in R&D. vol 6. issue 3. 2005-09-14. PMID:15869319. |
these effects were determined by measuring changes in hepatic levels of free radical scavenging enzymes such as superoxide dismutase (sod), glutathione-s-transferase (gst) and catalase, as well as levels of total glutathione (gsh), malondialdehyde (mda), aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2005-09-14 |
2023-08-12 |
rat |
| Marco Bongiovanni, Paola Cicconi, Simona Landonio, Paola Meraviglia, Letizia Testa, Antonio Di Biagio, Elisabetta Chiesa, Federica Tordato, Teresa Bini, Antonella d'Arminio Monfort. Predictive factors of lopinavir/ritonavir discontinuation for drug-related toxicity: results from a cohort of 416 multi-experienced HIV-infected individuals. International journal of antimicrobial agents. vol 26. issue 1. 2005-09-13. PMID:15878262. |
adverse events leading to lpv/r discontinuation were gastrointestinal symptoms in 40 cases, hyperlipidaemia in 27 and increase of aspartate aminotransferase (ast)/alanine aminotransferase (alt) in 10 patients. |
2005-09-13 |
2023-08-12 |
human |
| Masuhiro Nishimura, Mari Yamaguchi, Aiko Yamauchi, Nobuhiko Ueda, Shinsaku Nait. Role of soybean oil fat emulsion in the prevention of hepatic xenobiotic transporter mRNA up- and down-regulation induced by overdose of fat-free total parenteral nutrition in infant rats. Drug metabolism and pharmacokinetics. vol 20. issue 1. 2005-09-09. PMID:15770074. |
after tpn administration for 4 days, both serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels, which are indicators of hepatic dysfunction, in group 2 were significantly higher (p<0.001) than those in the other groups, whereas there were no differences between groups 1 and 3 in either serum ast or alt levels. |
2005-09-09 |
2023-08-12 |
human |
| Pardeep Sidhu, M L Garg, D K Dhawa. Time dependent study to evaluate the efficacy of zinc on hepatic marker enzymes and elemental profile in serum and liver of protein deficient rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 18. issue 1. 2005-09-08. PMID:15865415. |
the effects of different treatments were studied on enzymes like alkaline phosphatase (alp), aspartate aminotransferases (ast) and alanine aminotransferases (alt) in rat serum at different time intervals of 1, 2, 4 and 8 weeks and in the rat liver at the end of study. |
2005-09-08 |
2023-08-12 |
rat |
| Sebnem Atici, Ismail Cinel, Leyla Cinel, Nurcan Doruk, Gulcin Eskandari, Ugur Ora. Liver and kidney toxicity in chronic use of opioids: an experimental long term treatment model. Journal of biosciences. vol 30. issue 2. 2005-09-01. PMID:15886461. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), creatinin, blood urea nitrogen (bun) and malondialdehyde (mda) levels were measured in the serum. |
2005-09-01 |
2023-08-12 |
rat |
| J M Burke, J E Miller, D K Braue. The effectiveness of copper oxide wire particles as an anthelmintic in pregnant ewes and safety to offspring. Veterinary parasitology. vol 131. issue 3-4. 2005-09-01. PMID:15970388. |
blood was collected from lambs within 24h after birth and at 30 days of age for determination of the activity of the liver enzyme, aspartate aminotransferase (ast) in plasma. |
2005-09-01 |
2023-08-12 |
Not clear |
| Francis F Fountain, Elizabeth Tolley, Cary R Chrisman, Timothy H Sel. Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: a 7-year evaluation from a public health tuberculosis clinic. Chest. vol 128. issue 1. 2005-09-01. PMID:16002924. |
to determine the overall incidence of isoniazid (inh) hepatotoxicity in a public health tuberculosis clinic over a 7-year period, and to determine if systematic, limited aspartate aminotransferase (ast) monitoring would be of benefit in detecting inh hepatotoxicity. |
2005-09-01 |
2023-08-12 |
Not clear |
| Xu-Lin Chen, Zhao-Fan Xia, You-Xin Yu, Duo Wei, Chang-Rong Wang, Dao-Feng Be. p38 mitogen-activated protein kinase inhibition attenuates burn-induced liver injury in rats. Burns : journal of the International Society for Burn Injuries. vol 31. issue 3. 2005-08-25. PMID:15774288. |
hepatocellular injury (measured by serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt)) and hepatocellular function (determined by the indocyanine green dye retention rate (icg r15)) were assessed at 24 h post-burn. |
2005-08-25 |
2023-08-12 |
rat |
| Narasimhanaidu Kamalakkannan, Rajagopalan Rukkumani, Penumathsa Suresh Varma, Periyasamy Viswanathan, Kallikat Narayanan Rajasekharan, Venugopal Padmanabhan Meno. Comparative effects of curcumin and an analogue of curcumin in carbon tetrachloride-induced hepatotoxicity in rats. Basic & clinical pharmacology & toxicology. vol 97. issue 1. 2005-08-25. PMID:15943754. |
administration of carbon tetrachloride (3 ml/kg/week) for three months significantly (p<0.05) increased the levels of marker enzymes such as aspartate transaminase (ast), alkaline phosphatase (alp) and gamma-glutamyl transferase (ggt). |
2005-08-25 |
2023-08-12 |
rat |
| Isabelle Boutet, Anne-Leila Meistertzheim, Arnaud Tanguy, Marie-Thérèse Thébault, Dario Morag. Molecular characterization and expression of the gene encoding aspartate aminotransferase from the Pacific oyster Crassostrea gigas exposed to environmental stressors. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 140. issue 1. 2005-08-23. PMID:15792625. |
a partial cdna encoding cytosolic aspartate aminotransferase (ast) (ec 2.6.1.1) was isolated from a crassostrea gigas digestive gland library. |
2005-08-23 |
2023-08-12 |
Not clear |
| Ming-Yie Liu, Yu-Jung Cheng, Cheng-Kuang Chen, Bei-Chang Yan. Coexposure of lead- and lipopolysaccharide-induced liver injury in rats: involvement of nitric oxide-initiated oxidative stress and TNF-alpha. Shock (Augusta, Ga.). vol 23. issue 4. 2005-08-22. PMID:15803060. |
serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), tnf-alpha, nitric oxide (no), and lipid peroxidation (lpo) were determined in rats treated with pb and/or lps. |
2005-08-22 |
2023-08-12 |
rat |
| Einar Björnsson, Rolf Olsso. Outcome and prognostic markers in severe drug-induced liver disease. Hepatology (Baltimore, Md.). vol 42. issue 2. 2005-08-18. PMID:16025496. |
using logistic regression analysis, age, aspartate aminotransferase (ast) and bilirubin were found to independently predict death or liver transplantation in the hepatocellular group, whereas among patients with cholestatic/mixed liver injury, bilirubin was the only independent predictor. |
2005-08-18 |
2023-08-12 |
Not clear |
| Gamze Kökdil, Lülüfer Tamer, Bahadir Ercan, Ahmet Ilcim, Nurcan Aras, Uğur Ati. Effects of Nigella unguicularis fixed oil on blood biochemistry and oxidant/antioxidant balance in rats. Journal of ethnopharmacology. vol 99. issue 1. 2005-08-17. PMID:15848032. |
the serum transaminases ( aspartate transaminase (ast), alanine transaminase (alt)), alkaline phosphatase, bilirubin, blood urea nitrogen, urea, mean corpuscular haemoglobin concentration decreased significantly while albumin, mean corpuscular volume and fibrinogen levels increased significantly compared to control values. |
2005-08-17 |
2023-08-12 |
rat |
| Alexander Choukér, André Martignoni, Rolf J Schauer, Martin Dugas, Thomas Schachtner, Ines Kaufmann, Florian Setzer, Horst G Rau, Florian Löhe, Karl W Jauch, Klaus Peter, Manfred Thie. Alpha-gluthathione S-transferase as an early marker of hepatic ischemia/reperfusion injury after liver resection. World journal of surgery. vol 29. issue 4. 2005-08-16. PMID:15776301. |
routinely, hepatocellular damage is diagnosed by, for example, abnormal aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels and the prothrombin time (pt). |
2005-08-16 |
2023-08-12 |
Not clear |
| G Marchesini, S Avagnina, E G Barantani, A M Ciccarone, F Corica, E Dall'Aglio, R Dalle Grave, P S Morpurgo, F Tomasi, E Vitacolonn. Aminotransferase and gamma-glutamyltranspeptidase levels in obesity are associated with insulin resistance and the metabolic syndrome. Journal of endocrinological investigation. vol 28. issue 4. 2005-08-16. PMID:15966506. |
alanine and aspartate aminotransferases (alt and ast; no.=799) and gamma-glutamyltranspeptidase (ggt; no.=459) were analyzed in a group of treatment-seeking obese patients recruited in 12 italian medical centers. |
2005-08-16 |
2023-08-12 |
human |
| Niksa Turk, Rajko Kusec, Branimir Jaksic, Zdenka Tur. Humoral SPARC/osteonectin protein in plasma cell dyscrasias. Annals of hematology. vol 84. issue 5. 2005-08-11. PMID:15645230. |
a sparc showed a significant positive correlation with platelet count (r=0.72, p=0.000000, n=42), hemoglobin (r=0.52, p=0.00037, n=42), and igg level (r=0.43, p=0.0085, n=42) and negative correlation with beta(2)-microglobulin (r=-0.46, p=0.0023, n=42), aspartate aminotransferase (ast) (r=-0.42, p=0.0061, n=41), interleukin (il)-6 (r=-0.41, p=0.008, n=42), lactate dehydrogenase (ldh) (r=-0.36, p=0.02, n=41), and percentage of plasma cells in bone marrow aspirate (r=-0.34, p=0.029, n=42). |
2005-08-11 |
2023-08-12 |
Not clear |
| Wolfgang Dichtl, Wolfgang Vogel, Karin M Dunst, Wilhelm Grander, Hannes F Alber, Matthias Frick, Herwig Antretter, Günther Laufer, Otmar Pachinger, Gerhard Pölz. Cardiac hepatopathy before and after heart transplantation. Transplant international : official journal of the European Society for Organ Transplantation. vol 18. issue 6. 2005-08-11. PMID:15910296. |
plasma levels of gamma-glutamyl transferase (gamma-gt), alkaline phosphatase (ap), bilirubin, aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and total plasma protein. |
2005-08-11 |
2023-08-12 |
Not clear |
| Georges Férard, Françoise Imbert-Bismut, Djamila Messous, Annie Piton, Shigeru Ueda, Thierry Poynard, Jean-Marc Lessinge. A reference material for traceability of aspartate aminotransferase (AST) results. Clinical chemistry and laboratory medicine. vol 43. issue 5. 2005-08-08. PMID:15899678. |
a reference material for traceability of aspartate aminotransferase (ast) results. |
2005-08-08 |
2023-08-12 |
Not clear |
| Georges Férard, Françoise Imbert-Bismut, Djamila Messous, Annie Piton, Shigeru Ueda, Thierry Poynard, Jean-Marc Lessinge. A reference material for traceability of aspartate aminotransferase (AST) results. Clinical chemistry and laboratory medicine. vol 43. issue 5. 2005-08-08. PMID:15899678. |
standardization of aspartate aminotransferase (ast) determination is highly desirable for inter-laboratory comparison. |
2005-08-08 |
2023-08-12 |
Not clear |
| Ilter Kus, Murat Ogeturk, Hakan Oner, Semsettin Sahin, Hayrettin Yekeler, Mustafa Sarsilma. Protective effects of melatonin against carbon tetrachloride-induced hepatotoxicity in rats: a light microscopic and biochemical study. Cell biochemistry and function. vol 23. issue 3. 2005-08-04. PMID:15386534. |
serum aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), total and conjugated bilirubin levels were determined. |
2005-08-04 |
2023-08-12 |
rat |