| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xi Meng, Guoqi Yu, Tingyu Luo, Ruiyuan Zhang, Jun Zhang, Yongjie Li. Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring. Chemosphere. 2023-09-11. PMID:37696479. |
although the biochemical index difference including total cholesterol (tc), triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), alanine amino transaminase (alt), aspartate amino transferase (ast), and fasting blood glucose between exposed groups and the control group was not significant, transcriptome analyses showed that the differentially expressed genes (degs) in the 50 mg/kg/day pfbs exposure group were significantly related to protein digestion and absorption, peroxisome proliferator activated-receptor (ppar) signaling pathway, xenobiotic metabolism by cytochrome p450, glycine, serine and threonine metabolism, β-alanine metabolism, bile secretion, unsaturated fatty acid (fa) biosynthesis, and alanine, aspartate and glutamate metabolism. |
2023-09-11 |
2023-10-07 |
rat |
| Manaswita Tappata, Marina Farah, Chimaobi Anugwom, Eden Bisrat, Amir S Seid, Jose D Debe. Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up. The American journal of tropical medicine and hygiene. 2023-09-11. PMID:37696510. |
individuals on treatment had higher median aspartate aminotransferase (ast), alanine aminotransferase (alt), hbv dna, and median aminotransferase-to-platelet ratio index and fibrosis-4 scores. |
2023-09-11 |
2023-10-07 |
Not clear |
| D Giannuzzi, F Piccioli-Cappelli, S Pegolo, V Bisutti, S Schiavon, L Gallo, A Toscano, P Ajmone Marsan, L Cattaneo, E Trevisi, A Cecchinat. Observational study on the associations between milk yield, composition and coagulation properties with blood biomarkers of health in Holstein cows. Journal of dairy science. 2023-09-10. PMID:37690724. |
our findings revealed that milk yield and dmeo are positively and linearly associated with total cholesterol, nonesterified fatty acids (nefa), urea, aspartate aminotransferase (ast), γ-glutamyl transferase (ggt), total bilirubin, albumin, and ferric-reducing antioxidant power (frap), whereas they are negatively associated with glucose, creatinine, alkaline phosphatase, total reactive oxygen metabolites (romt), and proinflammatory proteins (i.e., ceruloplasmin, haptoglobin, and myeloperoxidase). |
2023-09-10 |
2023-10-07 |
Not clear |
| Tae-Geom Lee, Pil-Gyu Park, Yong-Beom Park, Ji-Hye Huh, Sang-Won Le. Clinical Link between the BARD Score at Diagnosis and Mortality during Follow-Up in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Journal of clinical medicine. vol 12. issue 17. 2023-09-09. PMID:37685746. |
the bard score was calculated by the sum of aspartate transaminase (ast)/alanine transaminase (alt) ratio ≥ 0.8 (+2 points), body mass index (bmi) ≥ 28 kg/m |
2023-09-09 |
2023-10-07 |
Not clear |
| Stamatina Vogli, Androniki Naska, Georgios Marinos, Maria-Iosifina Kasdagli, Philippos Orfano. The Effect of Vitamin E Supplementation on Serum Aminotransferases in Non-Alcoholic Fatty Liver Disease (NAFLD): A Systematic Review and Meta-Analysis. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686767. |
regarding aspartate aminotransferase (ast), patients in the experimental group experienced a reduction in serum levels, though smaller in absolute values [ast md = -4.65 iu/l, 95% ci (-7.44, -1.86) in studies conducted in asian populations] and of lower precision in non-asian studies [md = -5.60 iu/l, 95% ci (-11.48, 0.28)]. |
2023-09-09 |
2023-10-07 |
Not clear |
| Weikun Huang, Cong Xie, Nicolai J Wewer Albrechtsen, Miaomiao Sang, Zilin Sun, Karen L Jones, Michael Horowitz, Christopher K Rayner, Tongzhi W. Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes. Peptides. 2023-09-06. PMID:37673303. |
serum liver enzyme levels, including alanine transaminase (alt), aspartate transaminase (ast) and gamma-glutamyl transferase (ggt), are reportedly predictive of the risk of t2d. |
2023-09-06 |
2023-10-07 |
human |
| Noura S Abouzeinab, Nour Kahil, Najla Fakhruddin, Ramadan Awad, Mahmoud I Khali. Intraperitoneal hepato-renal toxicity of zinc oxide and nickel oxide nanoparticles in male rats: biochemical, hematological and histopathological studies. EXCLI journal. vol 22. 2023-09-04. PMID:37662710. |
the experimental groups exhibited elevated levels of aspartate aminotransferase (ast), alanine transaminase (alt), creatinine (crea), urea, lipid profile, glucose (glu), total protein (tp), albumin (alb) and malondialdehyde (mda), and decreased uric acid (ua), superoxide dismutase (sod), and glutathione (gsh). |
2023-09-04 |
2023-09-07 |
human |
| Mahmoud H Hatab, Aml M M Badran, Mahmoud A Elaroussi, Eman Rashad, Adel M Abu Taleb, Abdelmotaleb A Eloki. Effect of Zinc Oxide Nanoparticles as Feed Additive on Blood Indices, Physiological, Immunological Responses, and Histological Changes in Broiler Chicks. Biological trace element research. 2023-09-04. PMID:37667095. |
a significant increase in the concentrations of hemoglobin (hb), hematocrit (pcv%), red and white blood cell counts, total protein (tp), globulin (glob), aspartate transferase (ast), alanine transferase (alt), alkaline phosphatase (alp), superoxide dismutase (sod), glutathione peroxidase (gpx), and total antioxidant capacity (tac) and a significant decrease in malonaldehyde (mda), uric acid, and creatinine concentration were observed. |
2023-09-04 |
2023-09-07 |
Not clear |
| Qian Du, Mengmeng Teng, Luting Yang, Chao Meng, Yulan Qiu, Chuhui Wang, Jiaojiao Chen, Taotao Wang, Siying Chen, Yu Luo, Jinyao Sun, Yalin Don. Metabolic characteristics of voriconazole - Induced liver injury in rats. Chemico-biological interactions. 2023-09-02. PMID:37659626. |
vor - induced liver injury in rats was characterized by plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) elevation, the lipid droplets accumulation in liver, as well as inflammation and fibrosis. |
2023-09-02 |
2023-09-07 |
rat |
| Yuping Ding, Zuoyu Wang, Haiyan Niu, Quanjun Deng, Yanan Wang, Shihai Xi. FIB-4 is closer to FibroScan screen results to detecting advanced liver fibrosis and maybe facilitates NAFLD warning. Medicine. vol 102. issue 34. 2023-09-01. PMID:37653822. |
the magnitude of liver stiffness measured using fibroscan was positively correlated with aspartate transaminase/alanine aminotransferase (ast/alt) ratio (r = 0.419, p = .000), ast to platelet ratio index (apri) score (r = 0.309, p = .000), and fibrosis-4 score (fib-4) (r = 0.507, p = .000). |
2023-09-01 |
2023-09-07 |
Not clear |
| Samira Rastgoo, Sahand Tehrani Fateh, Mahlagha Nikbaf-Shandiz, Niloufar Rasaei, Yasaman Aali, Mohammad Zamani, Farideh Shiraseb, Omid Asbagh. The effects of L-carnitine supplementation on inflammatory and anti-inflammatory markers in adults: a systematic review and dose-response meta-analysis. Inflammopharmacology. 2023-09-01. PMID:37656233. |
l-carnitine supplementation had a significant effect on c-reactive protein (crp) (p < 0.001), interleukin-6 (il-6) (p = 0.001), tumor necrosis factor-α (tnf-α) (p = 0.002), malondialdehyde (mda) (p = 0.001), total antioxidant capacity (tac) (p = 0.029), alanine transaminase (alt) (p < 0.001), and aspartate transaminase (ast) (p < 0.001) in intervention, compared to the placebo group. |
2023-09-01 |
2023-09-07 |
Not clear |
| Liang-Gang Wang, Meng-Qian Liu, Xiao-Dong Xie, Yu-Bo Sun, Ming-Lin Zhang, Yi Zhao, Qi Chen, Yi-Qu Ding, Mei-Ling Yu, Zheng-Min Liang, Ting-Jun Hu, Wan-Wen Liang, Ying-Yi We. Effects of different water quality regulators on growth performance, immunologic function, and domestic water quality of GIFT tilapia. PloS one. vol 18. issue 8. 2023-08-30. PMID:37647293. |
however, the kmps and thps groups of gift tilapia exhibited significantly higher serum levels of aspartate aminotransferase (ast), alanine transaminase (alt), creatinine (cre) and blood urea nitrogen (bun) (p < 0.05), whereas they exhibited significantly decreased hsi (p < 0.05). |
2023-08-30 |
2023-09-07 |
Not clear |
| Pan Hu, Zhuo Zhang, Xiaolin Yu, Yinglin Wan. 5-Hydroxymethylfurfural Ameliorates Allergic Inflammation in HMC-1 Cells by Inactivating NF-κB and MAPK Signaling Pathways. Biochemical genetics. 2023-08-30. PMID:37648883. |
the bronchoalveolar lavage fluid (balf) and blood samples were collected for the detection of total and differential cell count as well as aspartate aminotransferase (ast), alanine aminotransferase (alt), ova-immunoglobulin e (ova-ige), ova-immunoglobulin g1 (ova-igg1), and pro-inflammatory cytokine levels. |
2023-08-30 |
2023-09-07 |
mouse |
| Chenchen Zhao, Jinxia Li, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Lin Lei, Xinwei L. Inhibition of cluster antigen 36 protects against fatty acids-induced lipid accumulation, oxidative stress, and inflammation in bovine hepatocytes. Journal of dairy science. 2023-08-29. PMID:37641277. |
in addition, hepatocytes isolated from healthy calves were treated with 0, 0.6, 1.2, or 2.4 mm nefa for 12 h; or infected with cd36 expressing adenovirus or cd36 silencing small interfering rna for 48 h and then treated with 1.2 mm nefa for 12 h. compared with healthy cows, clinically ketotic cows had greater concentrations of serum nefa and β-hydroxybutyrate (bhb) and activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) but lower serum glucose. |
2023-08-29 |
2023-09-07 |
cattle |
| Takeshi Ninchoji, Yuya Aoto, Natsuki Momo, Jun Maruyama, Hiroaki Ioi, Hayato Uchid. Management of children with obesity at local hospital and impact of COVID-19 pandemic. Frontiers in pediatrics. vol 11. 2023-08-28. PMID:37635787. |
there were no differences in body weight, obesity index (oi), blood pressure, or alanine transaminase (alt) levels between the groups; however, aspartate transaminase (ast) level was the highest in group c. in group c, only oi increased between the primary and secondary screenings; however, oi and body mass index (bmi) improved during the second screening and more children in the weight loss group followed lifestyle guidance. |
2023-08-28 |
2023-09-07 |
Not clear |
| Siriphan Bunsri, Nutnichawan Muenchamnan, Warangkana Naksen, Parichat Ong-Artborira. The Hematological and Biochemical Effects from Pesticide Exposure on Thai Vegetable Farmers. Toxics. vol 11. issue 8. 2023-08-25. PMID:37624212. |
in the male farmers, the activities of aspartate aminotransferase (ast), mean corpuscular hemoglobin (mch), and mean corpuscular hemoglobin concentration (mchc) were significantly higher in the pesticide users compared to the non-pesticide users, while the estimated glomerular filtration rate (egfr), hematocrit (hct), and red blood cells (rbc) were significantly lower ( |
2023-08-25 |
2023-09-07 |
Not clear |
| Junya Matsumi, Tetsufumi Sat. Protective effect of propofol compared with sevoflurane on liver function after hepatectomy with Pringle maneuver: A randomized clinical trial. PloS one. vol 18. issue 8. 2023-08-24. PMID:37616308. |
the primary and secondary outcomes were the postoperative peak levels of aspartate transaminase (ast) and alanine transaminase (alt), respectively. |
2023-08-24 |
2023-09-07 |
Not clear |
| Metin Özaslan, Dilek Peke. Evaluation of Laboratory Follow-up in Acne Patients Treated With Isotretinoin. Cutis. vol 112. issue 1. 2023-08-23. PMID:37611311. |
patient demographic data; cumulative isotretinoin doses; alanin transaminase (alt), aspartate transaminase (ast), γ-glutamyltransferase (ggt), creatinine kinase (ck), low-density lipoprotein cholesterol (ldl-c), and triglyceride (tg) levels during treatment were recorded. |
2023-08-23 |
2023-09-07 |
Not clear |
| Qingyuan He, Zekun Zeng, Man Zhao, Banjun Ruan, Pu Che. Association between thyroid function and diabetes peripheral neuropathy in euthyroid type 2 diabetes mellitus patients. Scientific reports. vol 13. issue 1. 2023-08-21. PMID:37596396. |
t2dm patients with dpn had obviously lower levels of aspartate aminotransferase (ast), alpha-hydroxybutyric dehydrogenase (α-hbdh), superoxide dismutase (sod), calcium (ca), creatinine (cr), uric acid (ua), retinol binding protein (rbp), total protein (tp), albumin (alb), alanine aminotransferase (alt) and ft4 than the t2dm patients without dpn (p < 0.05). |
2023-08-21 |
2023-09-07 |
human |
| Omnia A Basal, Rasha F Zahran, Entsar A Saa. Rifampicin efficacy against doxorubicin-induced cardiotoxicity in mice. The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology. vol 75. issue 1. 2023-08-21. PMID:37603165. |
heart histopathology and biochemical assays for heart function tests [creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), cardiac troponin i (ctni), atrial natriuretic peptide (anp), and vascular endothelial growth factor (vegf)], oxidative stress [malondialdehyde (mda) and superoxide dismutase (sod)], and minerals [phosphorus, sodium, potassium, and calcium] were done. |
2023-08-21 |
2023-09-07 |
mouse |