| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Sakai, S I Strasser, H M Shulman, S J McDonald, H G Schoch, G B McDonal. Severe hepatocellular injury after hematopoietic cell transplant: incidence, etiology and outcome. Bone marrow transplantation. vol 44. issue 7. 2010-01-12. PMID:19308033. |
although mild elevations of serum aminotransferase enzymes (aspartate and alanine (ast, alt)) do not carry an adverse prognosis, this is not the case with severe hepatocellular injury. |
2010-01-12 |
2023-08-12 |
Not clear |
| Gudrun Høiseth, Luca Morini, Aldo Polettini, Asbjørg Christophersen, Jørg Mørlan. Ethyl glucuronide in hair compared with traditional alcohol biomarkers--a pilot study of heavy drinkers referred to an alcohol detoxification unit. Alcoholism, clinical and experimental research. vol 33. issue 5. 2010-01-11. PMID:19298326. |
traditional biomarkers for heavy alcohol use include serum carbohydrate-deficient transferrin (cdt), the enzymes aspartate aminotransferase (ast), and alanine aminotransferase (alt) as well as gamma-glutamyl transferase (ggt). |
2010-01-11 |
2023-08-12 |
Not clear |
| Kamil K Hozyasz, Halina Gryglicka, Barbara Radomysk. [Benign acute childhood myositis (BACM)--cases report]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 27. issue 158. 2010-01-11. PMID:19856879. |
in all cases, creatine phosphokinase (cpk; the highest value at 8988 u/l) and aspartate aminotransferase (ast; the highest value at 329 u/l) values were elevated. |
2010-01-11 |
2023-08-12 |
Not clear |
| Xing-hua Gao, Xian-xiang Xu, Rong Pan, Ying Li, Yu-bin Luo, Yu-feng Xia, Kazuya Murata, Hideaki Matsuda, Yue Da. Saponin fraction from Astragalus membranaceus roots protects mice against polymicrobial sepsis induced by cecal ligation and puncture by inhibiting inflammation and upregulating protein C pathway. Journal of natural medicines. vol 63. issue 4. 2010-01-07. PMID:19548065. |
sam attenuated both inflammatory factors and their abilities to induce tissue dysfunction, which was mainly evidenced by decreased infiltration of polymorphonuclear leukocytes, tissue edema, and lung wet-to-dry weight ratio, lowered levels of myeloperoxidase (mpo), nitric oxide (no), lactate dehydrogenase (ldh), alanine aminotransferase (alt), and aspartate aminotransferase (ast) in serum, as well as downregulated expressions of inos and il-1beta mrna in livers. |
2010-01-07 |
2023-08-12 |
mouse |
| José A Mata-Marín, José L Fuentes-Allen, Jesús Gaytán-Martínez, Bulmaro Manjarrez-Téllez, Alberto Chaparro-Sánchez, Carla I Arroyo-Anduiz. APRI as a predictor of early viral response in chronic hepatitis C patients. World journal of gastroenterology. vol 15. issue 39. 2010-01-07. PMID:19842223. |
to evaluate the aspartate aminotransferase (ast) to platelet ratio index (apri) as a predictive factor of early viral response in chronic hepatitis c naive patients. |
2010-01-07 |
2023-08-12 |
Not clear |
| Mahmut Açikel, Sadik Sunay, Mustafa Koplay, Fuat Gündoğdu, Sule Karakelleoğl. Evaluation of ultrasonographic fatty liver and severity of coronary atherosclerosis, and obesity in patients undergoing coronary angiography. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology. vol 9. issue 4. 2010-01-04. PMID:19666428. |
aims were to examine associations (1) between non-alcoholic fatty liver disease (nafld) and the presence and severity of coronary artery disease (cad) and obesity, (2) between cad and nafld with aspartate aminotransferase (ast), alanine aminotransferase (alt) and gamma glutamiltransferase (ggt) levels. |
2010-01-04 |
2023-08-12 |
Not clear |
| Atsushi Kawasaki, Kenji Mimatsu, Youichi Kuboi, Hisao Kano, Takatsugu Oida, Sadao Aman. [Drug-induced liver injury associated with uracil/tegafur + folinate therapy]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 36. issue 11. 2009-12-29. PMID:19920397. |
laboratory data showed elevation of aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp). |
2009-12-29 |
2023-08-12 |
Not clear |
| A J Afolayan, M T Yakub. Effect of Bulbine natalensis Baker stem extract on the functional indices and histology of the liver and kidney of male Wistar rats. Journal of medicinal food. vol 12. issue 4. 2009-12-22. PMID:19735182. |
while the extract increased the activities of liver gamma-glutamyl transferase (ggt), alkaline phosphatase (alp), alanine and aspartate aminotransferase (alt and ast, respectively), and total bilirubin, globulin, and urea, the levels of albumin, conjugated bilirubin, inorganic phosphorus, and kidney alp and ggt decreased. |
2009-12-22 |
2023-08-12 |
rat |
| Amy G Shah, Alison Lydecker, Karen Murray, Brent N Tetri, Melissa J Contos, Arun J Sanya. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. vol 7. issue 10. 2009-12-16. PMID:19523535. |
we compared the performance of the fib4 index (based on age, aspartate aminotransferase [ast] and alanine aminotransferase [alt] levels, and platelet counts) with 6 other non-invasive markers of fibrosis in patients with nafld. |
2009-12-16 |
2023-08-12 |
Not clear |
| Veronika Butterweck, Immo Zdrojewski, Cheryl Galloway, Reginald Frye, Hartmut Derendor. Toxicological and Pharmacokinetic Evaluation of Concomitant Intake of Grapefruit Juice and Simvastatin in Rats after Repeated Treatment over 28 Days. Planta medica. vol 75. issue 11. 2009-12-15. PMID:19350484. |
no significant differences were detected for alanine (alt) and aspartate (ast) aminotranferases in all groups. |
2009-12-15 |
2023-08-12 |
rat |
| Virginie Messier, Antony D Karelis, Marie-Eve Robillard, Philippe Bellefeuille, Martin Brochu, Jean-Marc Lavoie, Rémi Rabasa-Lhore. Metabolically healthy but obese individuals: relationship with hepatic enzymes. Metabolism: clinical and experimental. vol 59. issue 1. 2009-12-15. PMID:19709695. |
outcome measures were hepatic enzymes (aspartate aminotransferase [ast], alanine aminotransferase [alt], alkaline phosphatase, and gamma-glutamyltransferase [ggt]], high-density lipoprotein cholesterol, triglycerides, triglycerides to high-density lipoprotein cholesterol ratio, apolipoprotein b, fatty liver index, body composition (dual-energy x-ray absorptiometry), and visceral adipose tissue (computed tomography). |
2009-12-15 |
2023-08-12 |
human |
| Anabela Pinto Rolo, João Soeiro Teodoro, Carmen Peralta, Joan Rosello-Catafau, Carlos M Palmeir. Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition. Transplant international : official journal of the European Society for Organ Transplantation. vol 22. issue 11. 2009-12-14. PMID:19619169. |
after reperfusion, serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were measured. |
2009-12-14 |
2023-08-12 |
Not clear |
| Maryam Tohidi, Hadi Harati, Farzad Hadaegh, Yadolladh Mehrabi, Fereidoun Aziz. Association of liver enzymes with incident type 2 diabetes: A nested case control study in an Iranian population. BMC endocrine disorders. vol 8. 2009-12-11. PMID:18533046. |
to investigate the association of aspartate aminotransferase (ast), alanin aminotranferase (alt) and gamma glutamyl transferase (ggt) with incident type 2 diabetes. |
2009-12-11 |
2023-08-12 |
Not clear |
| D R Griger, J B Higgs, D W Roan. Azathioprine hepatotoxicity is uncommon in patients with Rheumatic diseases. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 5. issue 2. 2009-12-11. PMID:19078358. |
information available from individual dmard charts included aza data (dates initiated, dose, indication for changing dose or stopping aza), co-administered dmards, and aspartate aminotransferase (ast) serum values. |
2009-12-11 |
2023-08-12 |
Not clear |
| Yutaka Tonomura, Yoko Mori, Mikinori Torii, Takeki Uehar. Evaluation of the usefulness of biomarkers for cardiac and skeletal myotoxicity in rats. Toxicology. vol 266. issue 1-3. 2009-12-11. PMID:19854236. |
the biomarkers assayed were fatty acid binding protein 3 (fabp3), myosin light chain 1 (mlc1), cardiac troponin i (ctni), cardiac troponin t (ctnt), aspartate transaminase (ast), lactate dehydrogenase (ldh) and creatine kinase (ck). |
2009-12-11 |
2023-08-12 |
rat |
| Omar M E Abdel Salam, Amany A Sleem, Enayat A Omara, Nabila S Hassa. Hepatoprotective effects of misoprostol and silymarin on carbon tetrachloride-induced hepatic damage in rats. Fundamental & clinical pharmacology. vol 23. issue 2. 2009-12-03. PMID:19298238. |
misoprostol, given at 100 or 1000 microg/kg, decreased aspartate aminotransferase (ast) by 28 and 43.6% and alkaline phosphatase (alp) by 19.3% and 53.4% respectively. |
2009-12-03 |
2023-08-12 |
rat |
| Neal D Freedman, James E Everhart, Karen L Lindsay, Marc G Ghany, Teresa M Curto, Mitchell L Shiffman, William M Lee, Anna S Lok, Adrian M Di Bisceglie, Herbert L Bonkovsky, John C Hoefs, Jules L Dienstag, Chihiro Morishima, Christian C Abnet, Rashmi Sinh. Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. Hepatology (Baltimore, Md.). vol 50. issue 5. 2009-12-03. PMID:19676128. |
at baseline, higher coffee consumption was associated with less severe steatosis on biopsy, lower serum aspartate aminotransferase (ast)/alanine aminotransferase (alt) ratio, alpha-fetoprotein, insulin, and homeostatic model assessment (homa2) score, and higher albumin (p < 0.05 for all). |
2009-12-03 |
2023-08-12 |
human |
| Yilmaz Cigremis, Huseyin Turel, Kevser Adiguzel, Muslum Akgoz, Asim Kart, Musa Karaman, Hasan Oze. The effects of acute acetaminophen toxicity on hepatic mRNA expression of SOD, CAT, GSH-Px, and levels of peroxynitrite, nitric oxide, reduced glutathione, and malondialdehyde in rabbit. Molecular and cellular biochemistry. vol 323. issue 1-2. 2009-12-01. PMID:19039654. |
hepatocellular damage was evaluated by aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels as well as histopathological examinations and immunohistochemical analysis. |
2009-12-01 |
2023-08-12 |
rabbit |
| Hui Guo, Jie Sun, Hui He, Guo-Cai Yu, Jing D. Antihepatotoxic effect of corn peptides against Bacillus Calmette-Guerin/lipopolysaccharide-induced liver injury in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 10. 2009-12-01. PMID:19577609. |
results showed that ili was manifested by a significant increase in levels of serum aspartate aminotransferase (ast)/alanine aminotransferase (alt) and liver malondialdehyde (mda)/nitric oxide (no) levels (p<0.01), and by a significant decrease in levels of superoxide dismutase (sod)/glutathione peroxidase (gpx) and glutathione (gsh) in liver (p<0.01). |
2009-12-01 |
2023-08-12 |
mouse |
| Shams Tabrez, Masood Ahma. Effect of wastewater intake on antioxidant and marker enzymes of tissue damage in rat tissues: implications for the use of biochemical markers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 10. 2009-12-01. PMID:19596398. |
in the present study, alteration in antioxidant enzymes superoxide dismutase (sod), catalase (cat), glutathione reductase (gr), glutathione-s-transferase (gst) and glutathione peroxidase (gpx) and marker enzymes of tissue damage alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) with laboratory exposure to wastewaters from aligarh (aww) and saharanpur (sww) were investigated in rat liver and kidney. |
2009-12-01 |
2023-08-12 |
rat |