| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Sun, Qing-Ming Che, Xin Zhao, Xiao-Ping P. Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats. European journal of pharmacology. vol 631. issue 1-3. 2010-05-17. PMID:20079350. |
the antifibrotic effects of baicalein were assessed directly by hepatic histology and indirectly by measuring levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), hepatic hyaluronic acid, laminin and procollagen type iii (pciii) in serum, as well as hydroxyproline and matrix metalloproteinases (mmps) in liver. |
2010-05-17 |
2023-08-12 |
rat |
| A A Oyagbemi, A A Odetol. Hepatoprotective effects of ethanolic extract of Cnidoscolus aconitifolius on paracetamol-induced hepatic damage in rats. Pakistan journal of biological sciences : PJBS. vol 13. issue 4. 2010-05-17. PMID:20437682. |
paracetamol overdose caused significant (p<0.05) increase in the plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), blood urea nitrogen (bun), triglycerides (tag) with total cholesterol (tc) and low density lipoprotein (ldl-cholesterol) and significant (p<0.05) decrease total protein (tp) and high density lipoprotein (hdl-cholesterol) in rats treated with paracetamol alone when compared with rats pre-treated with extract of cnidoscolus aconitifolius. |
2010-05-17 |
2023-08-12 |
rat |
| Kailash Prasa. Effects of vitamin E on serum enzymes and electrolytes in hypercholesterolemia. Molecular and cellular biochemistry. vol 335. issue 1-2. 2010-05-13. PMID:19730989. |
measurements of serum total cholesterol (tc), glucose, aspartate aminotransferase (ast), alkaline phosphatase (alp), alanine aminotransferase (alt), gamma-glutamyltransferase (ggt), albumin, creatinine, electrolytes [sodium (na), potassium (k), chloride (cl), and carbon dioxide (co2)] were made. |
2010-05-13 |
2023-08-12 |
Not clear |
| J Renugadevi, S Milton Prab. Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 62. issue 2. 2010-05-11. PMID:19409769. |
liver damage induced by cadmium was clearly shown by the increased activities of serum hepatic marker enzymes namely aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), gamma glutamyl transferase (ggt) and serum total bilirubin (tb) along with the increased level of lipid peroxidation indices (thiobarbituric acid reactive substances (tbars) and lipid hydroperoxides) and protein carbonyl contents in liver. |
2010-05-11 |
2023-08-12 |
rat |
| R Loomba, R Bettencourt, E Barrett-Conno. Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: the Rancho Bernardo Study. Alimentary pharmacology & therapeutics. vol 30. issue 11-12. 2010-05-11. PMID:19737152. |
the association between body-mass-index (bmi), alcohol consumption and their joint effect in increasing the risk of elevated serum alanine (alt) and aspartate (ast) is unclear in older community-dwelling adults. |
2010-05-11 |
2023-08-12 |
Not clear |
| Arthur Kenji Akimoto, Ana Luisa Miranda-Vilela, Penha Cristina Zaidan Alves, Luiz Carlos da Silva Pereira, Graciana Souza Lordelo, Cassia de Oliveira Hiragi, Izabel Cristina Rodrigues da Silva, Cesar Koppe Grisolia, Maria de Nazaré Klautau-Guimarãe. Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage. Free radical research. vol 44. issue 3. 2010-05-11. PMID:20109103. |
blood samples taken immediately after a race were submitted to genotyping, comet and tbars assays, biochemical analyses of creatine kinase (ck), aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2010-05-11 |
2023-08-12 |
human |
| Liliana Foia, Vasilica Toma, Didona Ungureanu, Mihaela Zlei, Anca Indrei, Doriana Forna, Danisia Habas, Sonia Nanesc. [Evaluation of oral injuries in experimental induced diabetes mellitus by analysis of some gingival fluid markers]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 112. issue 4. 2010-05-10. PMID:20209788. |
the objective of this study was to determine the relationship between the activity of the enzyme aspartate aminotransferase (ast) and il1-beta in gingival crevicular fluid (gcf) on animal model with experimentally induced diabetes mellitus and periodontal disease. |
2010-05-10 |
2023-08-12 |
Not clear |
| Yu Ou, Shan Zheng, Lin Lin, Qizhou Jiang, Xuegan Yan. Protective effect of C-phycocyanin against carbon tetrachloride-induced hepatocyte damage in vitro and in vivo. Chemico-biological interactions. vol 185. issue 2. 2010-05-10. PMID:20227401. |
in vivo, c-pc showed its capability to decrease serum alt and aspartate transaminase (ast) levels in ccl(4)-induced liver damage in mice. |
2010-05-10 |
2023-08-12 |
mouse |
| Olufunsho Awodele, Alade Akintonwa, Vincent O Osunkalu, Herbert A B Coke. Modulatory activity of antioxidants against the toxicity of Rifampicin in vivo. Revista do Instituto de Medicina Tropical de Sao Paulo. vol 52. issue 1. 2010-05-10. PMID:20305954. |
results showed rifampicin alone to raise (p < 0.05) liver function enzymes (aspartate amino transferase [ast], serum alanine amino transferase [alt] and total bilirubin) when compared with controls. |
2010-05-10 |
2023-08-12 |
rat |
| George A Asare, Bicky Ntombini, Michael C Kew, Christina P Kahler-Venter, Ezekiel N Norte. Possible adverse effect of high delta-alpha-tocopherol intake on hepatic iron overload: enhanced production of vitamin C and the genotoxin, 8-hydroxy-2'- deoxyguanosine. Toxicology mechanisms and methods. vol 20. issue 2. 2010-05-06. PMID:20100038. |
after 12 months, serum iron, reduced glutathione, catalase, vitamin c, oxygen radical absorbance capacity, lipid peroxidation, 8-hydroxy-2'-deoxyguanosine (8-ohdg), aspartate transaminase (ast), and alanine transaminase (alt) were measured. |
2010-05-06 |
2023-08-12 |
rat |
| Cristobal Pérez, Ignacio Munilla, Marta López-Alonso, Alberto Veland. Sublethal effects on seabirds after the Prestige oil-spill are mirrored in sexual signals. Biology letters. vol 6. issue 1. 2010-04-30. PMID:19726443. |
we measured the size of the red bill spot area and analysed plasma biochemical parameters indicative of sublethal effects of oil contamination in gulls, including glucose, total protein, creatinine, inorganic phosphorus, aspartate aminotransferase (ast) and gamma-glutamyl transferase. |
2010-04-30 |
2023-08-12 |
Not clear |
| C Allen Pinkham, Kenneth J Kraus. Liver function tests and mortality in a cohort of life insurance applicants. Journal of insurance medicine (New York, N.Y.). vol 41. issue 3. 2010-04-28. PMID:20377096. |
elevated aspartate aminotransferase (ast) and alanine aminotransferase (alt) have been shown to be associated with primary liver diseases, as well as increased all-cause mortality. |
2010-04-28 |
2023-08-12 |
Not clear |
| Jun Fang, Takahiro Seki, Haibo Qin, Gahininath Y Bharate, Arun K Iyer, Hiroshi Maed. Tissue protective effect of xanthine oxidase inhibitor, polymer conjugate of (styrene-maleic acid copolymer) and (4-amino-6-hydroxypyrazolo[3,4-d]pyrimidine), on hepatic ischemia-reperfusion injury. Experimental biology and medicine (Maywood, N.J.). vol 235. issue 4. 2010-04-28. PMID:20407081. |
a remarkable increase of liver enzymes in plasma (aspartate aminotransferase, ast; alanine aminotransferase, alt and lactate dehydrogenase, ldh) was detected three hours after reperfusion, whereas prior injection of sma-ahpp greatly suppressed this increase of ast, alt and ldh. |
2010-04-28 |
2023-08-12 |
rat |
| H Wedemeyer, W P Hofmann, S Lueth, P Malinski, R Thimme, F Tacke, J Wiegan. [ALT screening for chronic liver diseases: scrutinizing the evidence]. Zeitschrift fur Gastroenterologie. vol 48. issue 1. 2010-04-22. PMID:20072996. |
testing for aspartate aminotransferase (ast) or alanine aminotransferase (alt) is part of many routine screening approaches. |
2010-04-22 |
2023-08-12 |
Not clear |
| Suna Kalender, Fatma Gokce Uzun, Dilek Durak, Filiz Demir, Yusuf Kalende. Malathion-induced hepatotoxicity in rats: the effects of vitamins C and E. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 2. 2010-04-21. PMID:19941925. |
compared to the control group, the two groups also had significantly higher serum total cholesterol, alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) levels, and significantly lower triglyceride and very low density lipoprotein (vldl) levels. |
2010-04-21 |
2023-08-12 |
rat |
| C Hannig, B Spitzmüller, M Hanni. Transaminases in the acquired pellicle. Archives of oral biology. vol 54. issue 5. 2010-04-15. PMID:19321161. |
transaminases (ast, aspartate amino transferase; alt, alanine amino transferase) are relevant enzymes in physiology and pathology of the human organism. |
2010-04-15 |
2023-08-12 |
human |
| Johan Friso Lock, Eugen Schwabauer, Peter Martus, Nikolay Videv, Johann Pratschke, Maciej Malinowski, Peter Neuhaus, Martin Stockman. Early diagnosis of primary nonfunction and indication for reoperation after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 16. issue 2. 2010-04-13. PMID:20104485. |
in addition, the diagnosis of primary nonfunction (n = 3) was evaluated with limax and aspartate aminotransferase (ast) activity on the first postoperative day. |
2010-04-13 |
2023-08-12 |
Not clear |
| Nagao Totani, Akira Morita, Maki Nishinaka, Sayuri Tateishi, Haruyasu Kid. A novel body weight-loss promoting oil prepared with vegetable protein. Journal of oleo science. vol 59. issue 1. 2010-04-09. PMID:20032598. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), and histological analysis supported the safety of the improved oil. |
2010-04-09 |
2023-08-12 |
rat |
| Gregory Marslin, Caroline J Sheeba, V K Kalaichelvan, R Manavalan, P Neelakanta Reddy, G Frankli. Poly(D,L-lactic-co-glycolic acid) nanoencapsulation reduces Erlotinib-induced subacute toxicity in rat. Journal of biomedical nanotechnology. vol 5. issue 5. 2010-04-09. PMID:20201419. |
moreover, aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were significantly increased in the animals administered with free drug. |
2010-04-09 |
2023-08-12 |
rat |
| Jung Chao, Meng-Shiou Lee, Sakae Amagaya, Jiunn-Wang Liao, Jin-Bin Wu, Li-Kang Ho, Wen-Huang Pen. Hepatoprotective effect of shidagonglao on acute liver injury induced by carbon tetrachloride. The American journal of Chinese medicine. vol 37. issue 6. 2010-04-08. PMID:19938218. |
rats pretreated orally with sdgl(etoh) (100 and 500 mg/kg) and silymarin (200 mg/kg) for 3 consecutive days prior to the administration of a single dose of 50% ccl(4) (0.10 ml/100 g of bw, ip) significantly prevented the increases in the activities of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) in ccl(4)-treated rats. |
2010-04-08 |
2023-08-12 |
rat |