| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D T Maheshwari, M S Yogendra Kumar, Saroj K Verma, Vijay K Singh, Som Nath Sing. Antioxidant and hepatoprotective activities of phenolic rich fraction of Seabuckthorn (Hippophae rhamnoides L.) leaves. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 9. 2011-12-07. PMID:21723907. |
oral administration of prf at dose of 25-75 mg/kg body weight significantly protected from ccl(4) induced elevation in aspartate aminotransferase (ast), alanine aminotransferase (alt), γ-glutamyl transpeptidase (ggt) and bilirubin in serum, elevation in hepatic lipid peroxidation, hydroperoxides, protein carbonyls, depletion of hepatic reduced glutathione (gsh) and decrease in the activities of hepatic antioxidant enzymes; superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), glutathione reductase (gr) and glutathione-s-transferase (gst). |
2011-12-07 |
2023-08-12 |
rat |
| Sevcan Altaş, Göksel Kızıl, Murat Kızıl, Aydın Ketani, Parvez I Hari. Protective effect of Diyarbakır watermelon juice on carbon tetrachloride-induced toxicity in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 9. 2011-12-07. PMID:21740951. |
in vivo administration of carbon tetrachloride (ccl(4)) once a week for 28 days caused a significant elevation of serum markers of liver damage, aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tb) and decrease in albumin when compared to the control group. |
2011-12-07 |
2023-08-12 |
rat |
| D Djuricic, T Dobranic, J Grizelj, D Gracner, I Harapin, D Stanin, I Folnozic, I Getz, D Cvitkovic, M Samardzij. Concentrations of total proteins and albumins, and AST, AP, CK and GGT activities in the blood serum Boer and Saanen goats during puerperium. Reproduction in domestic animals = Zuchthygiene. vol 46. issue 4. 2011-12-05. PMID:21114794. |
in the obtained blood serum, the concentration of total proteins (pt) and albumin (alb), and the activity of enzymes aspartate aminotransferase (ast) [the enzyme commission number (ec number) 2. |
2011-12-05 |
2023-08-12 |
Not clear |
| Hiroyuki Fukuda, Ryu Ito, Masao Ohto, Akio Sakamoto, Eii Karasawa, Taketo Yamaguchi, Norihiro Shinozuka, Hui Zhu, Zhi-Biao Wang. Treatment of small hepatocellular carcinomas with US-guided high-intensity focused ultrasound. Ultrasound in medicine & biology. vol 37. issue 8. 2011-12-05. PMID:21645963. |
after treatment, serum alanine aminotransferase (alt) and serum aspartate aminotransferase (ast) levels were significantly higher than the baseline values; these levels recovered within 1 week. |
2011-12-05 |
2023-08-12 |
Not clear |
| Tao Wang, Maria Papoutsi, Marion Wiesmann, Marc DeCristofaro, M Craig Keselica, Elizabeth Skuba, Robert Spaet, Judit Markovits, Armin Wolf, Pierre Moulin, Francois Pognan, Paul Vancutsem, Lew Petryk, James Sutton, Salah-Dine Chibout, William Kluw. Investigation of correlation among safety biomarkers in serum, histopathological examination, and toxicogenomics. International journal of toxicology. vol 30. issue 3. 2011-12-05. PMID:21653914. |
treatment of blz945 in rats and monkeys increased serum alanine aminotransferase (alt) and aspartate transaminase (ast). |
2011-12-05 |
2023-08-12 |
rat |
| Felix Diaz González, Rodrigo Muiño, Víctor Pereira, Rómulo Campos, José Luis Benedit. Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. Journal of veterinary science. vol 12. issue 3. 2011-12-05. PMID:21897097. |
blood samples were obtained to measure beta-hydroxybutyrate (bhb), non-esterified fatty acids (nefa), triglycerides (tg), and the activity of aspartate transaminase (ast) and gamma-glutamyl transferase. |
2011-12-05 |
2023-08-12 |
Not clear |
| G B Silva Júnior, A B Libório, R M S Mota, K L S Abreu, A E B Silva, S M H A Araújo, E F Dahe. Acute kidney injury in AIDS: frequency, RIFLE classification and outcome. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 11. 2011-12-02. PMID:20922270. |
independent risk factors for aki were thrombocytopenia (or = 2.9, 95%ci = 1.5-5.6, p < 0.001) and elevation of aspartate aminotransferase (ast) (or = 3.5, 95%ci = 1.8-6.6, p < 0.001). |
2011-12-02 |
2023-08-12 |
Not clear |
| Raquel Villegas, Yong-Bing Xiang, Tom Elasy, Qiuyin Cai, Wanghong Xu, Honglan Li, Sergio Fazio, Macrae F Linton, David Raiford, Wei Zheng, Xiao Ou Sh. Liver enzymes, type 2 diabetes, and metabolic syndrome in middle-aged, urban Chinese men. Metabolic syndrome and related disorders. vol 9. issue 4. 2011-12-02. PMID:21495862. |
we examined associations between elevated aspartate aminotransferase (ast) and alanine aminotransferase (alt) with physical activity and obesity measures in middle-aged urban chinese men. |
2011-12-02 |
2023-08-12 |
Not clear |
| Sorimuthu P Subramanian, Subramanian Bhuvaneshwari, Gopalan S Prasat. Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats. General physiology and biophysics. vol 30. issue 3. 2011-11-28. PMID:21952437. |
assay of enzymes such as serum aspartate transaminase (ast), serum alanine transaminase (alt) and serum alkaline phosphatase (alp) revealed the non-toxic nature of e. hirta leaves. |
2011-11-28 |
2023-08-12 |
rat |
| Chen-Nen Chang, Yin-Cheng Huang, Den-Mei Yang, Kenichiro Kikuta, Kuo-Jen Wei, Toshihiko Kubota, Wen-Kuang Yan. A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 8. 2011-11-23. PMID:21715171. |
of the 17 treated patients (16 with world health organization grade iv and one with grade iii glioma), eight (47.1%) had an initial transient elevation in aspartate aminotransferase (ast)/alanine aminotransferase (alt). |
2011-11-23 |
2023-08-12 |
Not clear |
| Yusuf Yilmaz, Oya Yonal, Ramazan Kurt, Muharrem Bayrak, Bilge Aktas, Osman Ozdoga. Noninvasive assessment of liver fibrosis with the aspartate transaminase to platelet ratio index (APRI): Usefulness in patients with chronic liver disease: APRI in chronic liver disease. Hepatitis monthly. vol 11. issue 2. 2011-11-23. PMID:22087126. |
the aspartate aminotransferases (ast) to platelet ratio index (apri) may serve as a noninvasive marker to assess liver fibrosis. |
2011-11-23 |
2023-08-12 |
Not clear |
| Somaye Khosravi, Seyed Moayed Alavian, Ali Zare, Nasser Ebrahimi Daryani, Seyed-Mohammad Fereshtehnejad, Narges Ebrahimi Daryani, Mohammad Reza Keramati, Sina Abdollahzade, Sahar Taba Taba Vakil. Non-alcoholic fatty liver disease and correlation of serum alanin aminotransferase level with histopathologic findings. Hepatitis monthly. vol 11. issue 6. 2011-11-23. PMID:22087177. |
alanine aminotranferase (alt) and aspartate aminotransferase (ast) are indicators of hepatocellular injury. |
2011-11-23 |
2023-08-12 |
Not clear |
| Yu-Tang Tung, Chi-Chang Huang, Shang-Tse Ho, Yueh-Hsiung Kuo, Chi-Chen Lin, Chien-Tsong Lin, Jyh-Horng W. Bioactive phytochemicals of leaf essential oils of Cinnamomum osmophloeum prevent lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute hepatitis in mice. Journal of agricultural and food chemistry. vol 59. issue 15. 2011-11-22. PMID:21699244. |
the results revealed that post-treatment with 100 μmol/kg trans-cinnamaldehyde, (-)-aromadendrene, t-cadinol, or α-cadinol significantly decreased the aspartate aminotransferase (ast), alanine aminotransferase (alt), tumor necrosis factor-α (tnf-α), and interleukin 6 (il-6) levels in serum. |
2011-11-22 |
2023-08-12 |
mouse |
| Paul C Adams, James C Barto. A diagnostic approach to hyperferritinemia with a non-elevated transferrin saturation. Journal of hepatology. vol 55. issue 2. 2011-11-21. PMID:21354228. |
in this review, we provide an approach to interpreting the serum ferritin elevation in relationship to other clinical parameters including the patient history, transferrin saturation, serum concentrations of alanine, and aspartate aminotransferases (alt, ast), testing for hfe mutations, liver imaging, liver biopsy, and liver iron concentration. |
2011-11-21 |
2023-08-12 |
Not clear |
| Ivan Kristo, Julia Wilflingseder, Alexander Kainz, Julian Marschalek, Thomas Wekerle, Ferdinand Mühlbacher, Rainer Oberbauer, Martin Bodingbaue. Effect of intraportal infusion of tacrolimus on ischaemic reperfusion injury in orthotopic liver transplantation: a randomized controlled trial. Transplant international : official journal of the European Society for Organ Transplantation. vol 24. issue 9. 2011-11-21. PMID:21672049. |
the primary end point was liver function as assessed by aspartate transaminase (ast) or alanine transaminase (alt) levels 6 days after transplantation. |
2011-11-21 |
2023-08-12 |
Not clear |
| Khadiga G Adham, Nadia A Al-Eisa, Manal H Farhoo. Impact of heavy metal pollution on the hemogram and serum biochemistry of the Libyan jird, Meriones libycus. Chemosphere. vol 84. issue 10. 2011-11-18. PMID:21601906. |
in polluted jirds, the elevated activities of pseudocholinesterase (pche) and serum marker enzymes (alanine aminotransferase alt, aspartate aminotransferase ast and creatine kinase ck) strongly suggest functional damage of the liver and/or heart. |
2011-11-18 |
2023-08-12 |
human |
| Mohammad Ahmad, Yasser Elnakady, Muhammad Farooq, Muhammad Wadaa. Lithium induced toxicity in rats: blood serum chemistry, antioxidative enzymes in red blood cells and histopathological studies. Biological & pharmaceutical bulletin. vol 34. issue 2. 2011-11-15. PMID:21415540. |
furthermore, a marked inhibition in the levels of serum alanine and aspartate transaminases (alt and ast) reflected a stimulating transamination reaction in hepatic and renal tissues. |
2011-11-15 |
2023-08-12 |
rat |
| Steven P O'Hara, Pamela S Tietz Bogert, Christy E Trussoni, Xianming Chen, Nicholas F LaRuss. TLR4 promotes Cryptosporidium parvum clearance in a mouse model of biliary cryptosporidiosis. The Journal of parasitology. vol 97. issue 5. 2011-11-15. PMID:21506806. |
the liver enzymes alanine transaminase (alt) and aspartate transaminase (ast), and the proinflammatory cytokines tumor necrosis factor (tnf)-α, interferon (ifn)-γ, and interleukin (il)-6 peaked at 1 to 2 wk pi and normalized by 4 wk in infected c57bl mice. |
2011-11-15 |
2023-08-12 |
mouse |
| Dalila Bachir-Cherif, Denise Blum, Annamaria Braendli-Baiocco, Evelyne Chaput, Gonzalo Christiano Duran Pacheco, Nicholas Flint, Monika Haiker, Jean-Christophe Hoflack, Nicole Justies, Rachel Neff, Volkmar Starke, Guido Steiner, Charles Alexandre Tournillac, Thomas Singer, Geneviève Ubeaud-Séquier, Franz Schule. Characterization of post-surgical alterations in the bile duct-cannulated rat. Xenobiotica; the fate of foreign compounds in biological systems. vol 41. issue 8. 2011-11-15. PMID:21521079. |
in bdc animals, aspartate aminotransferase (ast) levels in plasma were transiently elevated and total bile acid levels were reduced. |
2011-11-15 |
2023-08-12 |
rat |
| Nirmal K Bairwa, Neeraj K Sethiya, S H Mishr. Protective effect of stem bark of Ceiba pentandra linn. against paracetamol-induced hepatotoxicity in rats. Pharmacognosy research. vol 2. issue 1. 2011-11-10. PMID:21808535. |
a significant (p < 0.05) reduction in serum enzymes got (alt), aspartate aminotransferase (ast), gpt alkaline phosphatase (alp), total bilirubin content and histopathological screening in the rats treated gave indication that ethyl acetate fraction of methanolic extract of ceiba pentandra possesses hepatoprotective potential against paracetamol-induced hepatotoxicity in rats. |
2011-11-10 |
2023-08-12 |
rat |