| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuai Zhang, Binan Lu, Xu Han, Lina Xu, Yan Qi, Lianhong Yin, Youwei Xu, Yanyan Zhao, Kexin Liu, Jinyong Pen. Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 55. 2013-09-23. PMID:23279844. |
pretreatment with tfs significantly decreased ccl4-induced elevation of serum aspartate transaminase (ast) and alanine transaminase (alt) activities as well as the relative liver weight. |
2013-09-23 |
2023-08-12 |
mouse |
| Setor K Kunutsor, Tanefa A Apekey, John Walle. Liver aminotransferases and risk of incident type 2 diabetes: a systematic review and meta-analysis. American journal of epidemiology. vol 178. issue 2. 2013-09-23. PMID:23729682. |
nine studies evaluated associations between aspartate aminotransferase (ast) levels and t2d risk, with a corresponding relative risk of 1.02 (95% ci: 0.99, 1.04). |
2013-09-23 |
2023-08-12 |
human |
| Hamidah Mohd Yusof, Norlaily Mohd Ali, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Kamariah Long, Suraini Abdul Aziz, Noorjahan Banu Alithee. Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-09-23. PMID:24058369. |
the evaluation of histological sections, serum biochemical markers (aspartate aminotransferase (ast), alanine aminotransferase (alt), and cholesterol and triglycerides (tg)), liver immune response level (nitric oxide (no)) and liver antioxidant level (superoxide dismutase (sod), ferric reducing antioxidant power (frap), and malondialdehyde (mda)) was conducted in order to compare the effects of nonfermented soybean extract (sbe) and fermented soybean extract (neste) on alcohol-induced liver damage in mice. |
2013-09-23 |
2023-08-12 |
mouse |
| Zhu Chen, Xiang-Pei Li, Zhi-Jun Li, Liang Xu, Xiao-Mei L. Reduced hepatotoxicity by total glucosides of paeony in combination treatment with leflunomide and methotrexate for patients with active rheumatoid arthritis. International immunopharmacology. vol 15. issue 3. 2013-09-20. PMID:23415907. |
hepatotoxicity was defined as an increase of at least 1.5-fold the upper limits of normal (uln) of alanine aminotransferase (alt) or aspartate aminotransferase (ast). |
2013-09-20 |
2023-08-12 |
Not clear |
| Asli Feride Kaptanoglu, Murat Uncu, Selcuk Ozyurt, Evren Hinca. Effect of isotretinoin on prothrombin time (PT), international normalized ratio (INR), and activated partial thromboplastin time (aPTT). The Journal of dermatological treatment. vol 24. issue 4. 2013-09-19. PMID:22188511. |
there were no statistically significant change in mean alanine aminotranferease (alt), aspartate aminotransferase (ast), pt, and inr values after treatment. |
2013-09-19 |
2023-08-12 |
Not clear |
| Huan Shen, Guo Tang, Guang Zeng, Yongjin Yang, Xingwei Cai, Dongli Li, Hongchen Liu, Ningxin Zho. Purification and characterization of an antitumor polysaccharide from Portulaca oleracea L. Carbohydrate polymers. vol 93. issue 2. 2013-09-19. PMID:23499074. |
furthermore the serum aspartate transanimase (ast), alanine transaminase (alt), urea nitrogen (bun), and creatinine levels in s180-bearing mice were significantly reversed by pop. |
2013-09-19 |
2023-08-12 |
mouse |
| Fang Yu, Huali Li, Yu Meng, Di Yan. Extraction optimization of Angelica sinensis polysaccharides and its antioxidant activity in vivo. Carbohydrate polymers. vol 94. issue 1. 2013-09-18. PMID:23544518. |
serum aspartate aminotransferase (ast), alanine aminotransfere (alt) and alkaline phosphatase (alp) levels were significantly restored toward normalization by the extracts (150 and 300 mg/kg body weight). |
2013-09-18 |
2023-08-12 |
Not clear |
| Tao Han, Diancai Zhang, Zan Fu, Yueming Sun, Wei Yang, Cuimei Yua. Retinol-binding protein 4 as a risk factor for cholesterol gallstone formation. Molecular and cellular biochemistry. vol 377. issue 1-2. 2013-09-13. PMID:23420326. |
part 2 metabolism indices, including serum rbp4, fg, tc, tg, hdl-c, low-density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt), and aspartate aminotransferase (ast) of 110 human cholesterol gallstone patients and 73 healthy controls were collected for further analysis. |
2013-09-13 |
2023-08-12 |
mouse |
| Ting Bai, Li-Hua Lian, Yan-Ling Wu, Ying Wan, Ji-Xing Na. Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells. International immunopharmacology. vol 15. issue 2. 2013-09-12. PMID:23318601. |
furthermore, tq significantly increased the survival against lps challenge in d-galactosamine (d-glan)-sensitized mice, and decreased the levels of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast), which were in line with in vitro results. |
2013-09-12 |
2023-08-12 |
mouse |
| K K Kuo, B N Wu, E Y Chiu, C J Tseng, J L Yeh, C P Liu, C Y Chai, I J Che. NO donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling. International journal of immunopathology and pharmacology. vol 26. issue 1. 2013-09-10. PMID:23527712. |
reperfusion was allowed for 4 h. serum was used for analysis of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2013-09-10 |
2023-08-12 |
rat |
| Hua-Zhong Ying, Yue-Huan Liu, Bing Yu, Zhi-Yuan Wang, Jia-Na Zang, Chen-Huan Y. Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 52. 2013-09-06. PMID:23123425. |
the results showed that oral administration of quercetin at doses of 30-60 mg/kg to hyperlipidemia rats for 14 days were highly effective in decreasing the levels of serum total cholesterol (tc), triglycerides (tg), low-density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2013-09-06 |
2023-08-12 |
rat |
| Rong Li, Lingyuan Xu, Tao Liang, Yongwen Li, Shijun Zhang, Xiaoqun Dua. Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 52. 2013-09-06. PMID:23146695. |
compared to model control, pr treatment effectively lowered the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), albumin (alb), total protein (tp) in hf rats. |
2013-09-06 |
2023-08-12 |
rat |
| Tung-Yuan Shih, Chien-Yi Pai, Ping Yang, Wen-Liang Chang, Ning-Chi Wang, Oliver Yoa-Pu H. A novel mechanism underlies the hepatotoxicity of pyrazinamide. Antimicrobial agents and chemotherapy. vol 57. issue 4. 2013-09-06. PMID:23357778. |
electron microscopy showed that pza and pa treatment of rats significantly increases aspartate transaminase (ast) and alanine aminotransferase (alt) activity and galactose single-point (gsp) levels (p < 0.005). |
2013-09-06 |
2023-08-12 |
rat |
| Noha Ahmed El-Boghdad. Increased cardiac endothelin-1 and nitric oxide in adriamycin-induced acute cardiotoxicity: protective effect of Ginkgo biloba extract. Indian journal of biochemistry & biophysics. vol 50. issue 3. 2013-09-05. PMID:23898483. |
caused a significant increase in the cardiac enzyme activities of aspartate transaminases (ast), lactate dehydrogenase (ldh) and creatine phosphokinase isoenzyme (ck-mb) in the serum of animals. |
2013-09-05 |
2023-08-12 |
rat |
| Nageh A El-Mahdy, Alaa E El-Sisi, Bedair I Dewidar, Karima I El-Desouk. Histamine protects against the acute phase of experimentally-induced hepatic ischemia/re-perfusion. Journal of immunotoxicology. vol 10. issue 1. 2013-09-04. PMID:22793375. |
rats in the control i/r group showed significant increases in hepatic malondialdehyde (mda), tnfα, and il-12 contents, and in plasma alanine transaminase (alt) and aspartate transaminase (ast) levels, along with significant decreases in hepatic reduced glutathione (gsh) content and marked diffuse histopathologic damage. |
2013-09-04 |
2023-08-12 |
rat |
| Norlaily Mohd Ali, Hamidah Mohd Yusof, Kamariah Long, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Mohd Puad Abdullah, Noorjahan Banu Alithee. Antioxidant and hepatoprotective effect of aqueous extract of germinated and fermented mung bean on ethanol-mediated liver damage. BioMed research international. vol 2013. 2013-09-03. PMID:23484140. |
liver superoxide dismutase (sod), malondialdehyde (mda), ferric reducing antioxidant power (frap), nitric oxide (no) levels, and serum biochemical profile such as aspartate transaminase (ast), alanine transaminase (alt), triglycerides (tg), and cholesterol and histopathological changes were examined for the antioxidant and hepatoprotective effects of these treatments. |
2013-09-03 |
2023-08-12 |
Not clear |
| Byung-Keun Yang, Guk-Nam Kim, Yong-Tae Jeong, Hun Jeong, Pradeep Mehta, Chi-Hyun Son. Hypoglycemic Effects of Exo-biopolymers Produced by Five Different Medicinal Mushrooms in STZ-induced Diabetic Rats. Mycobiology. vol 36. issue 1. 2013-09-02. PMID:23997607. |
it also reduced the plasma total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast) and, alanine aminotransferase (alt) levels by 9.22, 23.83, 16.93, and 27.31%, respectively. |
2013-09-02 |
2023-08-12 |
rat |
| A S Ozturk, M Guzel, T K Askar, I Ayteki. Evaluation of the hormones responsible for the gastrointestinal motility in cattle with displacement of the abomasum; ghrelin, motilin and gastrin. The Veterinary record. vol 172. issue 24. 2013-08-29. PMID:23723101. |
serum alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transferase (ggt), na, k, cl, ca and p concentrations were measured by spectrophotometer. |
2013-08-29 |
2023-08-12 |
cattle |
| T Wakiya, Y Sanada, K Mizuta, T Urahashi, Y Ihara, N Yamada, N Okada, S Egami, M Nakata, K Hakamada, Y Yasud. A comparison of open surgery and endovascular intervention for hepatic artery complications after pediatric liver transplantation. Transplantation proceedings. vol 45. issue 1. 2013-08-28. PMID:23375320. |
there were significant differences in the mean length of the operation for the first treatment of hepatic artery complications (open surgery, 428 minutes vs endovascular intervention, 160 minutes; p = .01) and in the mean value of the posttreatment aspartate aminotransferase (ast)/alanine aminotransferase (alt) (open surgery > endovascular intervention; p = .04/.05). |
2013-08-28 |
2023-08-12 |
Not clear |
| H Wang, L Xue, R Yan, Y Zhou, M S Wang, M J Cheng, H J Huan. Comparison of FIB-4 and APRI in Chinese HBV-infected patients with persistently normal ALT and mildly elevated ALT. Journal of viral hepatitis. vol 20. issue 4. 2013-08-28. PMID:23490387. |
fib-4 and aspartate aminotransferase (ast)-to-platelet ratio index (apri) were calculated for patients with chronic hbv infection undergoing biopsy. |
2013-08-28 |
2023-08-12 |
Not clear |