| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maogen Zhang, Sushma Karra, Waldemar Gorsk. Electrochemical coupled-enzyme assays at carbon nanotubes. Analytical chemistry. vol 86. issue 18. 2015-08-28. PMID:25180617. |
in the present work, its relevance to more challenging coupled-enzyme measurements was investigated by using a model enzyme pair comprising aspartate transaminase (ast) and malic dehydrogenase. |
2015-08-28 |
2023-08-13 |
Not clear |
| Yutaka Tonomura, Yuki Kato, Hiroyuki Hanafusa, Yuji Morikawa, Keigo Matsuyama, Takeki Uehara, Motonobu Ueno, Mikinori Tori. Diagnostic and predictive performance and standardized threshold of traditional biomarkers for drug-induced liver injury in rats. Journal of applied toxicology : JAT. vol 35. issue 2. 2015-08-28. PMID:25186495. |
traditional biomarkers such as alanine and aspartate aminotransferase (alt, ast) and total bilirubin (tbil) have been widely used for detecting drug-induced liver injury (dili). |
2015-08-28 |
2023-08-13 |
human |
| Young-Ah Cho, Kwantae Noh, Seong-Suk Jue, So-Youn Lee, Eun-Cheol Ki. Melatonin promotes hepatic differentiation of human dental pulp stem cells: clinical implications for the prevention of liver fibrosis. Journal of pineal research. vol 58. issue 1. 2015-08-28. PMID:25431168. |
in vivo therapeutic effects were evaluated by histopathology and by means of liver function tests including measurement of alanine transaminase (alt), aspartate transaminase (ast), and ammonia levels. |
2015-08-28 |
2023-08-13 |
mouse |
| Yu-Hsiu Tien, Bing-Huei Chen, Guoo-Shyng Wang Hsu, Wan-Teng Lin, Jui-Hua Huang, Yi-Fa L. Hepatoprotective and anti-oxidant activities of Glossogyne tenuifolia against acetaminophen-induced hepatotoxicity in mice. The American journal of Chinese medicine. vol 42. issue 6. 2015-08-27. PMID:25384447. |
the results showed that mice treated with gt had significantly decreased serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2015-08-27 |
2023-08-13 |
mouse |
| Hong He, Hongmei Wang, Mei Han, Yuguo Jiao, Congli Ma, Han Zhang, Zhou Zho. Study on changes of clinical indicators and key proteins from fluoride exposure. Biological trace element research. vol 160. issue 1. 2015-08-24. PMID:24907160. |
meanwhile, levels of alanine aminotransaminase (alt), aspartate aminotransaminase (ast), and alt/ast in groups 5 and 6 decreased significantly compared to those in control group (p < 0.05), as well as the concentration of uric acid (ua) in groups 3, 4, 5, and 6 exhibited the same trends (p < 0.05). |
2015-08-24 |
2023-08-13 |
rat |
| Lei Yu, Shaolong Yang, Lei Sun, Yan-Fang Jiang, Li-Ying Zh. Effects of selenium-enriched Agaricus blazei Murill on liver metabolic dysfunction in mice, a comparison with selenium-deficient Agaricus blazei Murill and sodium selenite. Biological trace element research. vol 160. issue 1. 2015-08-24. PMID:24908110. |
subsequent serum alanine aminotransferase (alt) level, aspartate aminotransaminase (ast) level, maleic dialdehyde (mda) level, hepatic total antioxidant status (taos), nuclear factor kappa b (nf-κb) level, polymorphonuclear cells (pmn) level, interleukin-1β (il-1β) level, inducible nitric oxide synthase (inos) level, tumor necrosis factor-α (tnf-α) level, intercellular adhesion molecule 1 (icam-1), and cyclooxygenase-2 (cox-2) were determined by elisa and immunohistochemistry, respectively. |
2015-08-24 |
2023-08-13 |
mouse |
| Walter R Taylor, Annette Fox, Khuong Thi Pham, Hoa Nguyen Minh Le, Ninh Thi Hai Tran, Giang Van Tran, Binh Thanh Nguyen, My Van Nguyen, Lien Thi Nguyen, Sophie Yacoub, Hoai Thi Thu Nguyen, Ha Hong Nguyen, Hien Duc Nguyen, Heiman Wertheim, Peter Horby, Jeremy Farrar, Lien Thi Minh Trinh, Kinh Van Nguye. Dengue in adults admitted to a referral hospital in Hanoi, Vietnam. The American journal of tropical medicine and hygiene. vol 92. issue 6. 2015-08-24. PMID:25918201. |
four (2.8%) patients had severe dengue: 1) d10 shock (n = 1) and 2) aspartate aminotransferase (ast) ≥ 1,000 iu/l (n = 3, d5 and d7). |
2015-08-24 |
2023-08-13 |
Not clear |
| Gokhan Bayramoglu, Hulyam Kurt, Aysegul Bayramoglu, Hasan Veysi Gunes, İrfan Degirmenci, Suat Cola. Preventive role of gallic acid on hepatic ischemia and reperfusion injury in rats. Cytotechnology. vol 67. issue 5. 2015-08-22. PMID:24811129. |
at the same time alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) were assayed in serum samples and compared statistically. |
2015-08-22 |
2023-08-13 |
rat |
| Ibrahim Sehitoglu, Levent Tumkaya, Recep Bedir, Ender Ozer, Medine Cumhur Cure, Yildiray Kalkan, Suleyman Yuce, Erkan Cur. Protective Effect of Infliximab Against Carbon Tetrachloride-Induced Hepatotoxicity. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 34. issue 2. 2015-08-20. PMID:26081035. |
in the ccl4 group, the serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt), and the liver tissue levels of transforming growth factor beta 1 (tgf-β1), interleukin 1 beta (il-1β), and adenosine deaminase (ada) were significantly higher than the levels of these same substances in the control and ccl4 + ib groups. |
2015-08-20 |
2023-08-13 |
rat |
| Nasser A Al-Asgah, Abdel-Wahab A Abdel-Warith, El-Sayed M Younis, Hassan Y Alla. Haematological and biochemical parameters and tissue accumulations of cadmium in Oreochromis niloticus exposed to various concentrations of cadmium chloride. Saudi journal of biological sciences. vol 22. issue 5. 2015-08-20. PMID:26288556. |
finally, the activities of aspartate aminotransferase (ast iu/l) and alanine aminotransferase (alt iu/l) showed a significant increase (p < 0.05) with increasing time and concentrations. |
2015-08-20 |
2023-08-13 |
Not clear |
| Jeonggeun Moon, WoongChol Kang, Pyung Chun Oh, Soon Yong Seo, Kyounghoon Lee, Seung Hwan Han, Taehoon Ahn, EakKyun Shi. Serum transaminase determined in the emergency room predicts outcomes in patients with acute ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention. International journal of cardiology. vol 177. issue 2. 2015-08-17. PMID:25442979. |
elevated serum aspartate and alanine aminotransferase (ast and alt) are often observed in patients with acute st-segment elevation myocardial infarction (stemi) and the condition is ascribed to liver hypoperfusion. |
2015-08-17 |
2023-08-13 |
Not clear |
| Liangjun Zhang, Ying Cheng, Xiaohuang Du, Sheng Chen, Xinchan Feng, Yu Gao, Shaoxue Li, Li Liu, Mei Yang, Lei Chen, Zhihong Peng, Yong Yang, Weizao Luo, Rongquan Wang, Wensheng Chen, Jin Cha. Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-08-14. PMID:26273316. |
serum alanine aminotransferase (atl) and aspartate aminotransferase (ast) levels were significantly decreased in bdl rats treated with swertianlarin for 14 days (p < 0.05). |
2015-08-14 |
2023-08-13 |
rat |
| Fashui Hong, Ling Wang, Xiaohong Yu, Yingjun Zhou, Jie Hong, Lei Shen. Toxicological effect of TiO2 nanoparticle-induced myocarditis in mice. Nanoscale research letters. vol 10. issue 1. 2015-08-13. PMID:26269254. |
the results showed that tio2 np exposure resulted in cardiac lesions coupling with pulmonary inflammation; increases of aspartate aminotransferase (ast), creatine kinase (ck), c-reaction protein (crp), lactate dehydrogenase (ldh), alpha-hydroxybutyrate dehydrogenase (hbdh), adhesion molecule-1 (icam-1), and monocyte chemoattractant protein-1 (mcp-1) levels; and a reduction of nitric oxide (nox) level in the serum. |
2015-08-13 |
2023-08-13 |
mouse |
| Nour El-Hoda A Zida. Hepato- and nephrotoxicity in male albino rats exposed to malathion and spinosad in stored wheat grains. Acta biologica Hungarica. vol 66. issue 2. 2015-08-12. PMID:26081270. |
biochemical parameters of liver functions [i.e., aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), acid phosphatase (acp) activity, as well as total protein, albumin, bilirubin and cholesterol levels] were severely affected especially at higher concentration. |
2015-08-12 |
2023-08-13 |
rat |
| Wedad Refaiea Al-Otaibi, Promy Virk, Mai Elobei. Ameliorative potential of stem bromelain on lead-induced toxicity in Wistar rats. Acta biologica Hungarica. vol 66. issue 2. 2015-08-12. PMID:26081271. |
the end points evaluated were, lead accumulation in kidney, liver and spleen, alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity, serum malonaldehyde (mda) cholesterol and triglycerides levels. |
2015-08-12 |
2023-08-13 |
rat |
| Bo-Kang Cui, Su Liu, Shu-Hong Li, Jun Wang, Qi-Bo Wang, Sheng-Ping Li, Xiao-Jun Li. Effect of tea polyphenol on oxidative injury in S180 cells induced hepatocarcinoma mice. International journal of molecular sciences. vol 13. issue 5. 2015-08-11. PMID:22754316. |
results showed that a significant increase in serum aspartate transaminase (ast), alkaline phosphatase (alp), alanine aminotransfere (alt), malondialdehyde (mda) level, decrease in serum white blood cells (wbc), serum total protein (tp), albumin (alb), a/g, tumor necrosis factor-α (tnf-α) and interferon-gamma (ifn-γ), liver reduced glutathione (gsh) levels were observed. |
2015-08-11 |
2023-08-12 |
mouse |
| F Tagliaro, F Bortolotti, F Crivellente, F Cittadin. Objective Diagnosis of Chronic Alcohol Abuse - Determination of Carbohydrate-Deficient Transferrin (CDT) with Capillary Electrophoresis. Forensic science review. vol 12. issue 1-2. 2015-08-11. PMID:26256030. |
the present paper reviews briefly in terms of diagnostic sensitivity and specificity the most important conventional markers of chronic alcohol abuse - e.g., γ-glutamyl transferase (ggt), erythrocyte mean corpuscular volume (mcv), aspartate aminotransferase (ast) and alanine aminotransferase (alt) - as well as those more recently proposed, namely aldehyde dehydrogenase (aldh), high density lipoprotein cholesterol, serum triglycerides, urate, fatty acid ethyl and methyl esters, phosphatidylethanol, dolichols, β-hexosaminidase and protein acetaldehyde adducts. |
2015-08-11 |
2023-08-13 |
Not clear |
| Hai-yan Tang, Qing-gui Xiao, Hong-bin Xu, Yi Zhan. Hypoglycemic activity and acute oral toxicity of chromium methionine complexes in mice. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 29. 2015-08-05. PMID:25081494. |
the anti-diabetic activity of crmet was explored in detail from the aspects of body weight (bw), blood glucose, triglyceride, total cholesterol, liver glycogen levels, aspartate transaminase (ast) and alanine transaminase (alt) levels. |
2015-08-05 |
2023-08-13 |
mouse |
| G L Araujo, A E D Vieira, E J Barreiro, L M Lima, C N Cardoso, N F Emiliano, M T Martins, S S Souza, A M De Souza, C Berto, M L Costa, L M Campos, F D França, C A Tagliat. Toxicological in vitro and subchronic evaluation of LASSBio-596. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 73. 2015-08-03. PMID:25139121. |
however, subchronic toxicity study results revealed changes in the blood parameters of amylase, alanine aminotransferase (alt), aspartate aminotransferase (ast), glucose and creatine kinase (ck) which is used for cardiotoxicity evaluation, although, did not identify any histopathological alterations. |
2015-08-03 |
2023-08-13 |
rat |
| W Qu, H Huang, K Li, C Qi. Danshensu-mediated protective effect against hepatic fibrosis induced by carbon tetrachloride in rats. Pathologie-biologie. vol 62. issue 6. 2015-08-03. PMID:25201143. |
the results showed that dss-administrated rats resulted in decreasing in hepatosomatic indexes, and lowering serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2015-08-03 |
2023-08-13 |
rat |