| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhaoyu Han, Baokui Yang, Zhen Yang, Yumeng X. Effects of 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester on growth and blood components in growing Holstein steers. Animal science journal = Nihon chikusan Gakkaiho. vol 88. issue 2. 2017-03-16. PMID:27311325. |
the concentration of alanine aminotransferase (alt) in tg2 increased (p < 0.05), but concentrations of aspartate aminotransferase (ast) in the treatment groups decreased (p < 0.05). |
2017-03-16 |
2023-08-13 |
Not clear |
| Miao Long, Shu-Hua Yang, Jian-Xin Han, Peng Li, Yi Zhang, Shuang Dong, Xinliang Chen, Jiayi Guo, Jun Wang, Jian-Bin H. The Protective Effect of Grape-Seed Proanthocyanidin Extract on Oxidative Damage Induced by Zearalenone in Kunming Mice Liver. International journal of molecular sciences. vol 17. issue 6. 2017-03-15. PMID:27231898. |
the results indicated that gspe could greatly reduce the zen-induced increase of serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities. |
2017-03-15 |
2023-08-13 |
mouse |
| Wei Li, Mengzhou Zhou, Ning Xu, Yong Hu, Chao Wang, Deyuan Li, Liegang Liu, Dongsheng L. Comparative analysis of protective effects of curcumin, curcumin-β-cyclodextrin nanoparticle and nanoliposomal curcumin on unsymmetrical dimethyl hydrazine poisoning in mice. Bioengineered. vol 7. issue 5. 2017-03-14. PMID:27710431. |
enzyme activities of serum alanine transaminase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) were analyzed by fully-automatic analyzer and neurotransmitter levels were determined with high performance liquid chromatography (hplc). |
2017-03-14 |
2023-08-13 |
mouse |
| Qi-Rui Bi, Jin-Jun Hou, Peng Qi, Chun-Hua Ma, Rui-Hong Feng, Bing-Peng Yan, Jian-Wei Wang, Xiao-Jian Shi, Yuan-Yuan Zheng, Wan-Ying Wu, De-An Gu. TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats. Scientific reports. vol 6. 2017-03-13. PMID:26961717. |
in the present study, sprague dawley (sd) rats, were administered vb (100, 200, and 400 mg/kg) intragastrically, experienced disturbed ecgs (lowered heart rate and elevated st-segment), increased levels of serum indicators (creatine kinase (ck), creatine kinase isoenzyme-mb (ck-mb), alanine aminotransferase (alt), aspartate aminotransferase (ast)) and serum interleukin (il-6, il-1β, tnf-α) at 2 h, 4 h, 6 h, 8 h, 24 h, and 48 h, which reflected that an inflammatory response, together with cardiotoxicity, were involved in vb-treated rats. |
2017-03-13 |
2023-08-13 |
rat |
| Hariprasath Lakshmanan, Jegadeesh Raman, Arjun Pandian, Kumaresan Kuppamuthu, Raaman Nanjian, Vikineswary Sabaratam, Murali Naid. Aqueous extract of Senecio candicans DC induce liver and kidney damage in a sub-chronic oral toxicity study in Wistar rats. Regulatory toxicology and pharmacology : RTP. vol 79. 2017-03-13. PMID:27177820. |
the results of sub-chronic study showed significant increase (p < 0.05) in serum uric acid, creatinine, aspartate transaminase (ast) and alanine transaminase (alp) levels. |
2017-03-13 |
2023-08-13 |
rat |
| Xufeng Tao, Xiance Sun, Lina Xu, Lianhong Yin, Xu Han, Yan Qi, Youwei Xu, Yanyan Zhao, Changyuan Wang, Jinyong Pen. Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats. Nutrients. vol 8. issue 7. 2017-03-13. PMID:27399769. |
the results demonstrated tfs decreased serum aspartate transaminase (ast), alanine aminotransferase (alt), myeloperoxidase (mpo), and lactate dehydrogenase (ldh) activities, improved liver histopathology and ultrastructure through hematoxylin-eosin (he) staining and electron microscope observation. |
2017-03-13 |
2023-08-13 |
rat |
| Ghada S El-Tanbouly, Mohammed S El-Awady, Nermeen A Megahed, Hatem A Salem, Hassan A El-Kashe. The NF-κB inhibitor celastrol attenuates acute hepatic dysfunction induced by cecal ligation and puncture in rats. Environmental toxicology and pharmacology. vol 50. 2017-03-13. PMID:28189063. |
protective effect of celastrol (1mg/kg, i.p., 1h before clp) was illustrated after 24h by preventing clp-induced hepatic histopathological changes and elevation in serum hepatic biomarkers [alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tb) and gamma aminotransferase (γ-gt)] without affecting mortality. |
2017-03-13 |
2023-08-13 |
rat |
| Iman Shirdel, Mohammad Reza Kalbassi, Milad Shokri, Roya Olyaei, Issa Sharifpou. The response of thyroid hormones, biochemical and enzymological biomarkers to pyrene exposure in common carp (Cyprinus carpio). Ecotoxicology and environmental safety. vol 130. 2017-03-10. PMID:27123973. |
the results revealed that pyrene at these concentrations significantly altered plasma levels of glucose, cholesterol, triglyceride, total protein, albumin, alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp). |
2017-03-10 |
2023-08-13 |
Not clear |
| Chaolun An, Jiajun Zhang, Hongjun Chu, Chunyan Gu, Feng Xiao, Fengwei Zhu, Rujian Lu, Hai Shi, Hongfei Zhang, Xin Y. Study of Gefitinib and Pemetrexed as First-Line Treatment in Patients with Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation. Pathology oncology research : POR. vol 22. issue 4. 2017-03-10. PMID:27126186. |
the main grade 3 or 4 non-hematological toxicities were infection, increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, fatigue, diarrhea and pneumonitis. |
2017-03-10 |
2023-08-13 |
human |
| Kuo-Chin Huang, Yi-Han Chiu, Kuang-Wen Liao, Chun-Yen Ke, Chung-Jen Lee, Yann-Fen C Chao, Ru-Ping Le. Prophylactic acetylsalicylic acid attenuates the inflammatory response but fails to protect exercise-induced liver damage in exercised rats. European journal of pharmacology. vol 786. 2017-03-10. PMID:27262381. |
moreover, aspartate aminotransferase (ast), alanine aminotransferase (alt) levels and histological hepatic damage increased significantly in the e+100mg asa group compared with the corresponding changes in the e group. |
2017-03-10 |
2023-08-13 |
rat |
| Ganping Bai, Guohe Yan, Guojian Wang, Ping Wan, Ronghua Zhan. Anti-hepatic fibrosis effects of a novel turtle shell decoction by inhibiting hepatic stellate cell proliferation and blocking TGF-β1/Smad signaling pathway in rats. Oncology reports. vol 36. issue 5. 2017-03-10. PMID:27633729. |
in a carbon tetrachloride (ccl4)-induced hf rat model, we observed that ntsd and tsp had similar effects on the improvement of liver functions in rats, including a decrease in serum alanine amino transferase (alt) and aspartate amino transferase (ast) serum concentrations and increased albumin content in addition to a marked attenuation of ccl4-induced liver damage and fibrosis. |
2017-03-10 |
2023-08-13 |
rat |
| E P S Conceição, E G Moura, P N Soares, X X Ai, M S Figueiredo, E Oliveira, P C Lisbo. High calcium diet improves the liver oxidative stress and microsteatosis in adult obese rats that were overfed during lactation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 92. 2017-03-09. PMID:27108106. |
at pn180, dietary calcium normalized food consumption, visceral fat, plasma aspartate aminotransferase (ast) and glycaemia. |
2017-03-09 |
2023-08-13 |
rat |
| Prarabdh C Badgujar, Gauri A Chandratre, Nitin N Pawar, A G Telang, N P Kurad. Fipronil induced oxidative stress involves alterations in SOD1 and catalase gene expression in male mice liver: Protection by vitamins E and C. Environmental toxicology. vol 31. issue 9. 2017-03-08. PMID:25721553. |
all three doses of fipronil caused a significant increase in the serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) level with concomitant increase in the absolute and relative weight of liver. |
2017-03-08 |
2023-08-13 |
mouse |
| Yuan-Zheng Gao, Lian-Feng Zhao, Jun Ma, Wei-Hong Xue, Hui Zha. Protective mechanisms of wogonoside against Lipopolysaccharide/D-galactosamine-induced acute liver injury in mice. European journal of pharmacology. vol 780. 2017-03-06. PMID:26921756. |
the results showed that wogonoside inhibited the production of serum alanine transaminase (alt), aspartate aminotransferase (ast), il-1β, tnf-α, and hepatic malondialdehyde (mda) content induced by lps/galn. |
2017-03-06 |
2023-08-13 |
mouse |
| Youngmin Kim, Mi-Jin Kwon, Jeong-Wook Choi, Min-Kyeong Lee, Chorong Kim, Jaehun Jung, Heny Aprianita, Heesop Nam, Taek-Jeong Na. Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet. International journal of molecular medicine. vol 38. issue 4. 2017-03-06. PMID:27498820. |
moreover, the consumption of boiled tuna extract restored the levels of superoxide dismutase (sod), catalase (cat), glutamic oxaloacetic transaminase (got), glutamic-pyruvate transaminase (gpt), aspartate transaminase (ast) and alanine transaminase (alt) to those of the control group. |
2017-03-06 |
2023-08-13 |
mouse |
| Thirssa H Grando, Matheus D Baldissera, Lucas T Gressler, Mariângela Facco de Sá, Bruna N Bortoluzzi, Andressa S Schafer, Rafael C Ebling, Renata P Raffin, Roberto C V Santos, Lenita M Stefani, Rodrigo Vaucher, Marta L R Leal, Silvia G Monteir. Melaleuca alternifolia anthelmintic activity in gerbils experimentally infected by Haemonchus contortus. Experimental parasitology. vol 170. 2017-03-06. PMID:27646626. |
h. contortus increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, as demonstrated by liver injury. |
2017-03-06 |
2023-08-13 |
Not clear |
| Enrico Fiore, Laura Perillo, Giuseppe Piccione, Matteo Gianesella, Silvia Bedin, Leonardo Armato, Elisabetta Giudice, Massimo Morgant. Effect of combined acetylmethionine, cyanocobalamin and α-lipoic acid on hepatic metabolism in high-yielding dairy cow. The Journal of dairy research. vol 83. issue 4. 2017-03-06. PMID:27845016. |
glucose, β-hydroxybutyrate (bhb), nonesterified fatty acids (nefa), triglycerides, total cholesterol (tc), alanine aminotransferase (alt), aspartate aminotransferase (ast), γ-glutamiltransferase (ggt), total bilirubin (tb), conjugated bilirubin (cb), total proteins (tp), globulins, albumin and urea concentrations were determined. |
2017-03-06 |
2023-08-13 |
Not clear |
| M Z El Azzouni, R F Mady, M R Gaafar, F M Arafa, A Elhadid. Protective capacity of cercarial transformation fluid alone or in combination with crude cercarial antigen against challenge infections of Schistosoma mansoni in mice. Journal of helminthology. vol 91. issue 1. 2017-02-27. PMID:26817577. |
moreover, there was a significant decrease in liver enzymes (alanine transaminase (alt) and aspartate transaminase (ast)) compared to infected control mice. |
2017-02-27 |
2023-08-13 |
mouse |
| F X Han, J H Gao, J H Ga. Clinical significance of combined liver function and high-sensitivity C-reactive protein measurement in children with hand-foot-mouth disease. Genetics and molecular research : GMR. vol 15. issue 3. 2017-02-27. PMID:27706779. |
the liver function [aspartate aminotransferase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) levels] and hs-crp expression were evaluated using standardized tests, and the clinical value of combined detection of these indices (in parallel and serially) was determined. |
2017-02-27 |
2023-08-13 |
Not clear |
| Ayman Yosry, Rabab Fouad, Shereen A Alem, Aisha Elsharkawy, Mohammad El-Sayed, Noha Asem, Ehsan Hassan, Ahmed Ismail, Gamal Esma. FibroScan, APRI, FIB4, and GUCI: Role in prediction of fibrosis and response to therapy in Egyptian patients with HCV infection. Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology. vol 17. issue 2. 2017-02-24. PMID:27353055. |
the aim of this study was to validate and compare the diagnostic performance of fibroscan, apri (aspartate aminotransferase (ast)-to-platelet ratio index), fib4, and guci (göteborg university cirrhosis index) for the prediction of hepatic fibrosis and treatment outcome in hcv-infected patients receiving pegylated interferon and ribavirin (peg-ifn/ribavirin). |
2017-02-24 |
2023-08-13 |
Not clear |