| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Qin Wang, Jin-Ge Wei, Meng-Jue Tu, Jian-Guo Gu, Wei Zhan. Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation. International journal of molecular sciences. vol 19. issue 12. 2019-03-26. PMID:30558169. |
the indexes evaluated included liver pathological changes, levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the serum, levels of reactive oxygen species (ros), malondialdehyde (mda), superoxide dismutase (sod), glutathione (gsh) and catalase (cat) in the liver, and related proteins levels (cyp2e1, pjnk and bax). |
2019-03-26 |
2023-08-13 |
mouse |
| Yongxia Yin, Yanguo Zhang, Haijun Li, Yan Zhao, Enbo Cai, Hongyan Zhu, Pingya Li, Jinping Li. Triterpenoids from fruits of Sorbus pohuashanensis inhibit acetaminophen-induced acute liver injury in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-03-25. PMID:30399585. |
the results showed that trds treatment significantly restrained the increase of serum aspartate transaminase (ast), alanine aminotransferase (alt), tumor necrosis factor (tnf-α), interleukin-1β (il-1β) and interleukin-6 (il-6), and hepatic malondialdehyde (mda) levels, as well as evidently reversed the decrease of hepatic superoxide dismutase (sod), glutathione (gsh) and catalase (cat) levels induced by apap. |
2019-03-25 |
2023-08-13 |
mouse |
| Rim Timoumi, Ines Amara, Fadwa Neffati, Mohamed Fadhel Najjar, Emna El Golli-Bennour, Hassen Bacha, Salwa Abid-Essef. Acute triflumuron exposure induces oxidative stress responses in liver and kidney of Balb/C mice. Environmental science and pollution research international. vol 26. issue 4. 2019-03-25. PMID:30539393. |
however, tfm caused an increase in the liver enzyme activities as aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), g-glutamyltranspeptidase (gtt), and total bilirubin (bilt) in a dose-dependent manner. |
2019-03-25 |
2023-08-13 |
mouse |
| Diego A Calvopina, Mark D Chatfield, Anna Weis, Miranda A Coleman, Manuel A Fernandez-Rojo, Charlton Noble, Louise E Ramm, Daniel H Leung, Peter J Lewindon, Grant A Ram. MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis. Hepatology (Baltimore, Md.). vol 68. issue 6. 2019-03-22. PMID:30014495. |
we investigated the combined use of serum mirnas and aspartate aminotransferase (ast) to platelet ratio (apri) to diagnose and assess cfld severity. |
2019-03-22 |
2023-08-13 |
Not clear |
| Yun-Dong Xie, Zi-Zhang Chen, Li-Hua Shao, Qiu-Tang Wang, Na Li, Wen-Fang Lu, Yan-Hong Xu, Yu-Qiong Gao, Li-Ying Guo, Hao-Le Liu, Yi-Ping Li, Guang-De Yang, Xiao-Li Bia. A new multifunctional hydroxytyrosol-clofibrate with hypolipidemic, antioxidant, and hepatoprotective effects. Bioorganic & medicinal chemistry letters. vol 28. issue 18. 2019-03-21. PMID:30119959. |
aspartate and lactate transaminases (ast and alt) activities, alkalines phosphatases (alp), and total bilirubin (tbil) levels. |
2019-03-21 |
2023-08-13 |
mouse |
| T Amirabadi Farahani, H Amanlou, N E Farsuni, M Kazemi-Bonchenar. Interactions of protein levels fed to Holstein cows pre- and postpartum on productive and metabolic responses. Journal of dairy science. vol 102. issue 1. 2019-03-21. PMID:30391172. |
however, a reduction in serum aspartate aminotransferase (ast) concentration was observed in 19post cows compared with 16post cows (68.30 vs. 98.24 u/l) when cows were fed 12pre. |
2019-03-21 |
2023-08-13 |
Not clear |
| Yu-Hong Liu, Qiong-Hui Huang, Xue Wu, Jia-Zhen Wu, Jia-Li Liang, Guo-Sheng Lin, Lie-Qiang Xu, Xiao-Ping Lai, Zi-Ren Su, Jian-Nan Che. Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities. Food & function. vol 9. issue 11. 2019-03-20. PMID:30375606. |
the results indicate that pd effectively improves the survival of mice with apap-induced hepatotoxicity, significantly alleviating histopathologic alterations in the liver, and decreasing the serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2019-03-20 |
2023-08-13 |
mouse |
| Fatma Sm Moawed, Sawsan M El-Sonbaty, Somaya Z Mansou. Gallium nanoparticles along with low-dose gamma radiation modulate TGF-β/MMP-9 expression in hepatocellular carcinogenesis in rats. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 41. issue 3. 2019-03-20. PMID:30859905. |
5 times per week for 6 weeks) significantly reduced serum levels of alpha-fetoprotein (afp), aspartate transferase (ast), alanine transferase (alt), and gamma-glutamyltransferase (ggt). |
2019-03-20 |
2023-08-13 |
rat |
| Kun Liu, Xiu-Mei Ren, Qing-Sheng You, Ming-Ming Gu, Fei Wang, Shuo Wang, Chun-Hui Ma, Wei-Nan Li, Qing Y. Ameliorative Effect of Dangguibuxue Decoction against Cyclophosphamide-Induced Heart Injury in Mice. BioMed research international. vol 2018. 2019-03-19. PMID:30515415. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), creatine kinase (ck), and lactic dehydrogenase (ldh) in serum were detected by commercial kits. |
2019-03-19 |
2023-08-13 |
mouse |
| Gülay Çiftci, Özkan Yiğit, Alper Çiftc. The effects of the conjunctival Brucella vaccine on some biochemical parameters in sheep. Tropical animal health and production. vol 51. issue 2. 2019-03-18. PMID:30145690. |
alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), glucose, total protein, and albumin levels were measured using commercial autoanalyzer in sera. |
2019-03-18 |
2023-08-13 |
Not clear |
| Pimpisid Koonyosying, Sarawut Kongkarnka, Chairat Uthaipibull, Saovaros Svasti, Suthat Fucharoen, Somdet Srichairatanakoo. Green tea extract modulates oxidative tissue injury in beta-thalassemic mice by chelation of redox iron and inhibition of lipid peroxidation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-18. PMID:30372872. |
plasma non-transferrin bound iron (ntbi), malondialdehyde (mda), alanine aminotransferase (alt), aspartate aminotransferase (ast), hepcidin and insulin; tissue iron and mda were measured. |
2019-03-18 |
2023-08-13 |
mouse |
| Josko Ivica, Stephen Hil. The potential of reducing AST testing in hospital settings. Clinical biochemistry. vol 64. 2019-03-15. PMID:30543792. |
aspartate aminotransferase (ast) is regularly ordered with alanine aminotransferase (alt) to assess liver integrity. |
2019-03-15 |
2023-08-13 |
Not clear |
| Afef Nahdi, Imen Hammami, Ridha Ben Ali, Olfa Kallech-Ziri, Ahmed El May, Michèle Véronique El Ma. Effect of Hypericum humifusum aqueous and methanolic leaf extracts on biochemical and histological parameters in adult rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-14. PMID:30218859. |
at the same time, alanine transaminase (alt), aspartate transaminase (ast) and lactate dehydrogenase (ldh) were assayed in plasma samples. |
2019-03-14 |
2023-08-13 |
rat |
| Arturo González Raya, Ramón Coca Zúñiga, Eva Martín Salid. Isolated elevation of aspartate aminotransferase (AST) in an asymptomatic patient due to macro-AST. Journal of clinical laboratory analysis. vol 33. issue 2. 2019-03-11. PMID:30320474. |
isolated elevation of aspartate aminotransferase (ast) in an asymptomatic patient due to macro-ast. |
2019-03-11 |
2023-08-13 |
Not clear |
| Arturo González Raya, Ramón Coca Zúñiga, Eva Martín Salid. Isolated elevation of aspartate aminotransferase (AST) in an asymptomatic patient due to macro-AST. Journal of clinical laboratory analysis. vol 33. issue 2. 2019-03-11. PMID:30320474. |
a rare and benign cause of isolated aspartate aminotransferase (ast) increase is due to the presence of macro aspartate aminotransferase (macro-ast). |
2019-03-11 |
2023-08-13 |
Not clear |
| Sarah Bussler, Mandy Vogel, Diana Pietzner, Kristian Harms, Theresa Buzek, Melanie Penke, Norman Händel, Antje Körner, Ulrich Baumann, Wieland Kiess, Gunter Flemmin. New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase): Effects of age, sex, body mass index, and pubertal stage. Hepatology (Baltimore, Md.). vol 68. issue 4. 2019-03-07. PMID:28926121. |
the present study aims to clarify the effects of sex, age, body mass index (bmi), and puberty on transaminase serum levels in children and adolescents and to provide new age- and sex-related percentiles for alanine aminotransferase (alt), aspartate aminotransferase (ast), and γ-glutamyltransferase (ggt). |
2019-03-07 |
2023-08-13 |
human |
| O Atli, V Kilic, M Baysal, G Kilic, G Gormus, S Ucarcan, B Korkut, S Ilgi. Assessment of trazodone-induced cardiotoxicity after repeated doses in rats. Human & experimental toxicology. vol 38. issue 1. 2019-03-07. PMID:29774748. |
electrocardiogram records, serum aspartate aminotransferase (ast), lactate dehydrogenase, creatine kinase-myoglobin band, cardiac troponin-t (ctn-t) levels, dna damage in cardiomyocytes, and histologic view of heart tissues were evaluated. |
2019-03-07 |
2023-08-13 |
rat |
| Cong Zhang, Qian Zhang, Yangyang Pang, Xiaozhe Song, Nan Zhou, Jiang Wang, Long He, Jiahuan Lv, Yameng Song, Yongxu Cheng, Xiaozhen Yan. The protective effects of melatonin on oxidative damage and the immune system of the Chinese mitten crab (Eriocheir sinensis) exposed to deltamethrin. The Science of the total environment. vol 653. 2019-03-07. PMID:30759581. |
moreover, del exposure significantly induced functional damage of the hepatopancreas and mitochondria, with a significant increase in alanine aminotransferase (alt), aspartate aminotransferase (ast), acid phosphatase (acp) and alkaline phosphatase (akp) activities in the hepatopancreas and the ratio of albumin/globulin (alb/glb) in serum, which indicated the permeability and integrity of the membranes were damaged and had caused cell damage. |
2019-03-07 |
2023-08-13 |
Not clear |
| Zhenhui Wu, Yingyu Wang, Xian Meng, Xinjie Wang, Zhenlin Li, Shihui Qian, Yingjie Wei, Luan Shu, Yongfang Ding, Peijuan Wang, Yunru Pen. Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells. International journal of molecular medicine. vol 42. issue 6. 2019-03-06. PMID:30272289. |
the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh) and nitric oxide (no) were measured using colorimetric assays. |
2019-03-06 |
2023-08-13 |
human |
| Mehmet Akif Yesilipek, Gulsun Karasu, Zuhre Kaya, Baris B Kuskonmaz, Vedat Uygun, Ilkiz Dag, Onur Ozudogru, Mehmet Erte. A Phase II, Multicenter, Single-Arm Study to Evaluate the Safety and Efficacy of Deferasirox after Hematopoietic Stem Cell Transplantation in Children with β-Thalassemia Major. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. vol 24. issue 3. 2019-03-05. PMID:29155313. |
from baseline to week 52, there were decreases in median concentrations of alanine aminotransferase (alt), from 30.0 to 17.0 iu/l, and aspartate aminotransferase (ast), from 35.5 to 26.0 iu/l. |
2019-03-05 |
2023-08-13 |
Not clear |